Michael S. Rafii

ORCID: 0000-0003-2640-2094

MedicineEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.6Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease (TRC-PAD) Project: An Overview

The Journal of Prevention of Alzheimer s Disease(2020)10.14283/jpad.2020.45

Top 15%

1.4DataRank

Top 15%43 citations

Reisa A. Sperling, Jeffrey L. Cummings, Michael Donohue, Oliver Langford, Gustavo Jimenez‐Maggiora +6 more

Papers

Driven by 59 papers — median percentile 74. Top paper: “Trial of Solanezumab in Preclinical Alzheimer’s Disease”.

Trial of Solanezumab in Preclinical Alzheimer’s Disease

New England Journal of Medicine(2023)10.1056/nejmoa2305032

N/A

4.9DataRank · unranked

390 citations

Michael Donohue, Rema Raman, Michael S. Rafii, Keith Johnson, Colin L. Masters +10 more

Revised criteria for the diagnosis and staging of Alzheimer’s disease

Nature Medicine(2024)10.1038/s41591-024-02988-7

N/A

3.5DataRank · unranked

167 citations

Scott J. Andrews, Thomas G. Beach, Teresa Buracchio, Billy Dunn, Ana Graf +15 more

Plasma Aβ42/Aβ40 and phospho‐tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease

Alzheimer s & Dementia(2023)10.1002/alz.13542

N/A

3.4DataRank · unranked

149 citations

Oliver Langford, Rema Raman, Michael Donohue, Sara Abdel‐Latif, Matthew R. Meyer +16 more

Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains

Brain(2023)10.1093/brain/awad398

N/A

1.8DataRank · unranked

20 citations

Anne Labonté, Cynthia Picard, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm +84 more

The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease (TRC-PAD) Project: An Overview

The Journal of Prevention of Alzheimer s Disease(2020)10.14283/jpad.2020.45

Top 15%

1.4DataRank

Top 15%43 citations

Reisa A. Sperling, Jeffrey L. Cummings, Michael Donohue, Oliver Langford, Gustavo Jimenez‐Maggiora +6 more

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

Alzheimer s & Dementia(2024)10.1002/alz.13859

N/A

1.2DataRank · unranked

2424 citations

J. Scott Andrews, Thomas G. Beach, Teresa Buracchio, Billy Dunn, Ana Graf +15 more

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

N/A

1.1DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Down syndrome

Nature Reviews Disease Primers(2020)10.1038/s41572-019-0143-7

N/A

1.0DataRank · unranked

914 citations

Brian G. Skotko, Michael S. Rafii, André Strydom, Sarah E. Pape, Diana W. Bianchi +3 more

The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores

Communications Biology(2022)10.1038/s42003-022-03795-x

Top 22%

0.924DataRank

Top 22%16 citations

Elizabeth Vance, Matthew Cloward, Ed Ringger, Louisa Dayton, Mark Ebbert +94 more

Alzheimer's disease associated with Down syndrome: a genetic form of dementia

The Lancet Neurology(2021)10.1016/s1474-4422(21)00245-3

N/A

0.885DataRank · unranked

363 citations

Shahid Zaman, Sigan L. Hartley, Michael S. Rafii, Elizabeth Head, María Carmona‐Iragui +1 more

The AHEAD 3‐45 Study: Design of a prevention trial for Alzheimer's disease

Alzheimer s & Dementia(2022)10.1002/alz.12748

N/A

0.847DataRank · unranked

282 citations

Reisa A. Sperling, Michael Donohue, Jin Zhou, Claire Roberts, Michael C. Irizarry +12 more

Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2214634120

N/A

0.725DataRank · unranked

125 citations

Phoebe Imms, Mingxi Cheng, Anar Amgalan, Nahian F. Chowdhury, Roy J Massett +83 more

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

The Alzheimer's Disease Neuroimaging Initiative Clinical Core

Alzheimer s & Dementia(2024)10.1002/alz.14167

Top 31%

0.638DataRank

Top 31%19 citations

Michael Donohue, Rema Raman, Michael S. Rafii, Ronald C. Petersen, for the Alzheimer's Disease Neuroimaging Initiative +1 more

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Translational Psychiatry(2021)10.1038/s41398-021-01602-5

N/A

0.637DataRank · unranked

69 citations

Jiaying Lu, Hong‐Qi Li, Yuxiang Yang, Jiehui Jiang, Mei Cui +94 more

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Journal of Alzheimer s Disease(2020)10.3233/jad-201167

N/A

0.598DataRank · unranked

53 citations

Michael S. Rafii, Fan Zhang, James Hall, David Julovich, Beau M. Ances +20 more

Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment

Brain(2024)10.1093/brain/awae315

N/A

0.597DataRank · unranked

21 citations

Mirthe Coenen, Charles DeCarli, Alberto De Luca, Ewoud van der Lelij, Alzheimer’s Disease Neuroimaging Initiative +81 more

Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis

Brain(2023)10.1093/brain/awad100

N/A

0.593DataRank · unranked

51 citations

Anna L. Svenningsson, Anna C. van Loenhoud, Colin Groot, Frederik Barkhof, Olof Strandberg +84 more

Increased Medial Temporal Tau Positron Emission Tomography Uptake in the Absence of Amyloid-β Positivity

JAMA Neurology(2023)10.1001/jamaneurol.2023.2560

N/A

0.581DataRank · unranked

47 citations

Alexis Moscoso, Jesús Silva‐Rodríguez, Michael J. Pontecorvo, Michael D. Devous, Pablo Aguiar +95 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

N/A

0.542DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

N/A

0.510DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Immunotherapy responsiveness and risk of relapse in Down syndrome regression disorder

Translational Psychiatry(2023)10.1038/s41398-023-02579-z

N/A

0.464DataRank · unranked

21 citations

Noemi Alice Spinazzi, Robyn A. Filipink, Panteha Hayati-Rezvan, Ryan Kammeyer, Lina Patel +21 more

Current advances and unmet needs in Alzheimer's disease trials for individuals with Down syndrome: Navigating new therapeutic frontiers

Alzheimer s & Dementia(2025)10.1002/alz.70258

N/A

0.416DataRank · unranked

15 citations

Laura Videla, María Carmona‐Iragui, Juan Fortea, Michael S. Rafii, Isabel Barroeta

Deep learning to quantify the pace of brain aging in relation to neurocognitive changes

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2413442122

N/A

0.406DataRank · unranked

14 citations

Phoebe Imms, Nahian F. Chowdhury, Nikhil N. Chaudhari, Heng Ping, Haoqing Wang +86 more

The history of Down syndrome–associated Alzheimer's disease; past, present, and future

Alzheimer s & Dementia(2025)10.1002/alz.70158

N/A

0.385DataRank · unranked

12 citations

María Carmona‐Iragui, Ira T. Lott, Elizabeth Head, Thomas Wisniewski, Michael S. Rafii +8 more

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives

Alzheimer s & Dementia(2025)10.1002/alz.70536

N/A

0.345DataRank · unranked

9 citations

Reisa A. Sperling, Alicia Algeciras‐Schimnich, Hidenori Arai, Anna M. Barron, Tammie L.S. Benzinger +39 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

N/A

0.312DataRank · unranked

7 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [18F]-fluoroethoxybenzovesamicol positron emission tomography imaging

Neurobiology of Aging(2025)10.1016/j.neurobiolaging.2025.01.008

N/A

0.312DataRank · unranked

7 citations

Alexander C. Conley, Brian D. Boyd, John P. Begnoche, Rachel Schlossberg, Allison Stranick +10 more

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome

EBioMedicine(2024)10.1016/j.ebiom.2024.105433

N/A

0.299DataRank · unranked

6 citations

Lam‐Ha T. Dang, Alice Lee, Sharon J. Krinsky‐McHale, Deborah Pang, Lisa Melilli +72 more

Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference

Alzheimer s & Dementia(2025)10.1002/alz.70309

N/A

0.269DataRank · unranked

5 citations

Lucía Maure-Blesa, Beau M. Ances, Lisi Flores Aguilar, Sigan L. Hartley, Jason Hassenstab +54 more

Characteristics of discordance between amyloid positron emission tomography and plasma amyloid-β 42/40 positivity

Translational Psychiatry(2024)10.1038/s41398-024-02766-6

N/A

0.241DataRank · unranked

4 citations

Young Ho Park, Young Chul Youn, Min Ju Kang, Kyu Hwan Shim, Jae‐Won Jang +73 more

Deep learning enhanced ALPS reveals genetic and environmental factors of brain glymphatic function

eBioMedicine(2026)10.1016/j.ebiom.2026.106133

N/A

0.208DataRank · unranked

3 citations

Hao Wu, Wenbiao Xian, Yifan Zheng, Wenxuan Du, Xinyi Chen +1916 more

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

N/A

0.165DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Multi-organ AI endophenotypes chart the heterogeneity of brain, eye and heart pan-disease

Nature Mental Health(2026)10.1038/s44220-025-00560-x

N/A

0.165DataRank · unranked

2 citations

Junhao Wen, Christos Davatzikos, Ye Ella Tian, Michael S. Rafii, Keenan A. Walker +12 more

Integrating individualized connectome with amyloid pathology improves predictive modeling of future cognitive decline

Communications Medicine(2025)10.1038/s43856-025-01170-5

N/A

0.165DataRank · unranked

2 citations

Qolamreza Razlighi, Yunglin Gazes, Christian Habeck, Yaakov Stern, for the Alzheimer’s Disease Neuroimaging Initiative +95 more

Multi-organ MRI digitizes biological aging clocks across proteomics, metabolomics, and genetics

medRxiv(2025)10.1101/2025.07.10.25331263

N/A

0.104DataRank · unranked

1 citations

Zhiyuan Song, Michael R. Duggan, Guray Erus, Dhivya Srinivasan, Ye Ella Tian +10 more

“Being brave, being seen, and having your voice heard”: Perspectives of self‐advocates and families toward accessible and impactful research of Alzheimer's disease in down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70999

N/A

0.104DataRank · unranked

1 citations

Lauren Ptomey, Elizabeth Head, Ann Cohen, Joseph Mike Briones, Henry Shaw +16 more

Interpretable discriminant analysis for functional data supported on random nonlinear domains with an application to Alzheimer’s disease

Journal of the Royal Statistical Society Series B (Statistical Methodology)(2024)10.1093/jrsssb/qkae023

N/A

0.104DataRank · unranked

1 citations

Wenbo Zhang, Swati Rane Levendovszky, Alzheimer’s Disease Neuroimaging Initiative, Michael W Weiner, Paul Aisen +86 more

Clinical and neuropathological analysis of Down syndrome over 7 decades of life

Journal of Neuropathology & Experimental Neurology(2024)10.1093/jnen/nlae110

N/A

0DataRank · unranked

1 citations

Vanessa Goodwill, Jennifer Ngolab, H Kim, Solana Leisher, Sahar Salehi +4 more

Estimating Socio-Economic Status for Alzheimer's Disease Trials

The Journal of Prevention of Alzheimer s Disease(2024)10.14283/jpad.2024.88

N/A

0DataRank · unranked

1 citations

J D Grill, Doris P. Molina‐Henry, Gregory A. Jicha, Michael S. Rafii, Aiyi Liu +4 more

Safety Profile of a Cognitively Unimpaired Older Population with Elevated Cerebral Amyloid in a 4.5-Year Clinical Trial

The Journal of Prevention of Alzheimer s Disease(2024)10.14283/jpad.2024.138

N/A

0DataRank · unranked

0 citations

K.C. Holdridge, Michele Mancini, Michael S. Rafii, M. Case, Chakib Battioui +4 more

Immunotherapy Responsiveness and Risk of Relapse in Down Syndrome Regression Disorder

Research Square(2023)10.21203/rs.3.rs-2521595/v1

N/A

0DataRank · unranked

2 citations

Noemi Alice Spinazzi, Robyn A. Filipink, Panteha Hayati-Rezvan, Ryan Kammeyer, Lina Patel +21 more

Safety and tolerability of lumbar puncture for the evaluation of Alzheimer's disease

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2023)10.1002/dad2.12431

N/A

0DataRank · unranked

12 citations

Victoria García, Garrett Miller, Michael Donohue, Leslie M. Shaw, Mike Weiner +5 more

Detection and treatment of Alzheimer’s disease in its preclinical stage

Nature Aging(2023)10.1038/s43587-023-00410-4

N/A

0DataRank · unranked

149 citations

Paul Aisen, Michael S. Rafii

Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group

Journal of Neurodevelopmental Disorders(2022)10.1186/s11689-022-09435-z

N/A

0DataRank · unranked

40 citations

Mara L. Becker, George T. Capone, Kathleen M. Egan, Juan Fortea, Benjamin L. Handen +7 more

Alzheimer’s Disease in Down Syndrome: Progress in the Design and Conduct of Drug Prevention Trials

CNS Drugs(2020)10.1007/s40263-020-00740-6

N/A

0DataRank · unranked

25 citations

Michael S. Rafii

Recruitment into the Alzheimer Prevention Trials (APT) Webstudy for a Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD)

The Journal of Prevention of Alzheimer s Disease(2020)10.14283/jpad.2020.46

N/A

0DataRank · unranked

40 citations

Taylor Clanton, Oliver Langford, Michael S. Rafii, Elizabeth Shaffer, Joshua D. Grill +5 more

Brain cholinergic terminal density utilizing [18F]‐fluoroethoxybenzovesamicol PET in adults with Down's syndrome: Relationship to amyloid PET and cognitive performance

Alzheimer s & Dementia(2025)10.1002/alz.70134

N/A

0DataRank · unranked

3 citations

Alexander C. Conley, Brian D. Boyd, John P. Begnoche, Rachel Schlossberg, Allison Stranick +8 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

N/A

0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Imaging and plasma biomarkers for pathological accumulation in Down syndrome

Brain(2025)10.1093/brain/awaf418

N/A

0DataRank · unranked

2 citations

Ziqiao Jiao, James T. Kennedy, Ann D. Cohen, Zinayida Schlachetzki, Melissa Petersen +21 more

Relationship between use of anti‐platelet agents, oral anti‐coagulants, and Aβ burden with cerebral microhemorrhages in cognitively asymptomatic adults

Alzheimer s & Dementia(2025)10.1002/alz.70167

N/A

0DataRank · unranked

0 citations

Dobri Baldaranov, Michael Donohue, Clifford R. Jack, Reisa A. Sperling, Paul Aisen +2 more

The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD): Experience from the First 3 Years

The Journal of Prevention of Alzheimer s Disease(2020)10.14283/jpad.2020.47

N/A

0DataRank · unranked

22 citations

Oliver Langford, Taylor Clanton, Gustavo Jimenez‐Maggiora, Rema Raman, Michael S. Rafii +5 more

Sleep chart of biological aging clocks in middle and late life

medRxiv(2025)10.1101/2025.08.08.25333313

N/A

0DataRank · unranked

0 citations

Zhiyuan Song, Filippos Anagnostakis, Zhijian Yang, Ye Ella Tian, Michael R. Duggan +21 more

A head-to-head comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

medRxiv(2025)10.1101/2025.03.18.25324200

N/A

0DataRank · unranked

1 citations

Julie C. Price, Bradley Christian, Michael S. Rafii, Matthew Zammit

From understanding to action: Exploring molecular connections of Down syndrome to Alzheimer's disease for targeted therapeutic approach

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12580

N/A

0DataRank · unranked

13 citations

Michael S. Rafii, Robert A. Rissman, Sonal Sukreet

De novo variants in immune regulatory genes in Down syndrome regression disorder

Journal of Neurology(2024)10.1007/s00415-024-12521-y

N/A

0DataRank · unranked

7 citations

Abhik K. Banerjee, Mellad Khoshnood, Benjamin N. Vogel, Natalie K. Boyd, Lina Nguyen +10 more

Greater White Matter Hyperintensity Volume Is Associated with the Number of Microhemorrhages in Preclinical Alzheimer's Disease

The Journal of Prevention of Alzheimer s Disease(2024)10.14283/jpad.2024.139

N/A

0DataRank · unranked

11 citations

Aaron P. Schultz, Michael J Properzi, R. Yaari, W-Y W Yau, Adam M. Brickman +11 more

Addressing challenges in health care and research for people with Down syndrome

The Lancet(2024)10.1016/s0140-6736(24)00478-1

N/A

0DataRank · unranked

14 citations

Eimear McGlinchey, Joaquı́n M. Espinosa, Michael S. Rafii, Juan Fortea

Assessing amyloid PET positivity and cognitive function in Down syndrome to guide clinical trials targeting amyloid

Alzheimer s & Dementia(2024)10.1002/alz.14068

N/A

0DataRank · unranked

17 citations

Caihong Yan, Sigan L. Hartley, Ben L. Handen, Julie K. Wisch, Anna H. Boehrwinkle +3 more

Michael S. Rafii

Indexed papers

Top data-sharing exemplar

Papers