Alex Sparreboom

MedicineBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 35 papers. Top paper: “Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy”.

Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy

Clinical and Translational Science(2020)10.1111/cts.12915

N/A

0.971DataRank · unranked

35 citations

Shuiying Hu, Alex Sparreboom, Deanna L. Kroetz, Tore Bjerregaard Stage

Preclinical pharmacokinetics of paclitaxel and docetaxel

Anti-Cancer Drugs(1998)10.1097/00001813-199801000-00001

N/A

0.751DataRank · unranked

148 citations

Olaf van Tellingen, Willem J. Nooijen, Jos H. Beijnen, Alex Sparreboom

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2

Pharmacogenomics(2005)10.1517/14622416.6.2.115

N/A

0.723DataRank · unranked

123 citations

Kees Nooter, Jaap Verweij, Milin R Acharya, William D Figg, Alex Sparreboom +1 more

DPYD Testing: Time to Put Patient Safety First

Journal of Clinical Oncology(2023)10.1200/jco.22.02364

N/A

0.561DataRank · unranked

41 citations

Susan E. Bates, Gabriel A. Brooks, William L. Dahut, Robert B. Diasio, Wafik S. El‐Deiry +17 more

Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition

Kidney International(2021)10.1016/j.kint.2021.08.022

N/A

0.515DataRank · unranked

30 citations

JY Kim, Bijay Bisunke, Laura A. Jayne, Josie A. Silvaroli, Michael S. Balzer +12 more

Gilteritinib-induced upregulation of S100A9 is mediated through BCL6 in acute myeloid leukemia

Blood Advances(2021)10.1182/bloodadvances.2021005614

N/A

0.471DataRank · unranked

11 citations

Jae Yoon Jeon, Zahra Talebi, Daelynn R. Buelow, Josie A. Silvaroli, Moray J. Campbell +4 more

Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy

JCI Insight(2023)10.1172/jci.insight.164646

N/A

0.416DataRank · unranked

15 citations

Thomas Drabison, Mahesh R. Nepal, Richard H. Ho, Alix F. Leblanc, Alice A. Gibson +20 more

Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies

Journal of Chromatography B(2021)10.1016/j.jchromb.2021.122591

N/A

0.406DataRank · unranked

14 citations

Yang Li, Muhammad Erfan Uddin, Alex Sparreboom, Shuiying Hu, Yan Jin

Targeting OCT2 with Duloxetine to Prevent Oxaliplatin-induced Peripheral Neurotoxicity

Cancer Research Communications(2022)10.1158/2767-9764.crc-22-0172

N/A

0.385DataRank · unranked

12 citations

Hanieh Taheri, Yang Li, Zahra Talebi, Muhammad Erfan Uddin, Yan Jin +6 more

MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia

International Journal of Molecular Sciences(2022)10.3390/ijms23158607

N/A

0.360DataRank · unranked

10 citations

Eric D. Eisenmann, Yang Li, Kevin M. Huang, Dominique A. Garrison, Zahra Talebi +21 more

Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method

Journal of Chromatography B(2022)10.1016/j.jchromb.2022.123437

N/A

0.360DataRank · unranked

10 citations

Yang Li, Eric D. Eisenmann, William D. Figg, Sharyn D. Baker, Alex Sparreboom +2 more

Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0332

N/A

0.345DataRank · unranked

9 citations

Mike Boeckman, Yan Yang, Kevin M. Huang, Peter de Bruijn, Mahesh R. Nepal +11 more

Resazurin dye is an in vivo sensor of kidney tubular function

Kidney International(2024)10.1016/j.kint.2024.12.008

N/A

0.165DataRank · unranked

2 citations

Isaac Z. Karel, Josie A. Silvaroli, Eman Ahmed, JY Kim, Amanda Stayton +31 more

Determination and Disposition of the Aromatase Inhibitor Exemestane in CYP3A-Deficient Mice

Molecules(2025)10.3390/molecules30071440

N/A

0.108DataRank · unranked

1 citations

Eman Ahmed, Peng Hu, Alex Sparreboom, Shuiying Hu, Hanieh Taheri

Determination and disposition of meta-iodobenzylguanidine in plasma and heart of transporter-deficient mice by UPLC-MS/MS

Journal of Chromatography B(2023)10.1016/j.jchromb.2023.123699

N/A

0DataRank · unranked

2 citations

Yan Jin, Sharyn D. Baker, Daniel Addison, Alex Sparreboom, Zahra Talebi

Data from Impact of ABCB1 Allelic Variants on QTc Interval Prolongation

(2023)10.1158/1078-0432.c.6518514

N/A

0DataRank · unranked

0 citations

Erin R. Gardner, Richard Piekarz, Reuben Howden, Xiaohong Chen, Sukyung Woo +14 more

Data from Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation

(2023)10.1158/1078-0432.c.6530622

N/A

0DataRank · unranked

0 citations

Mingqing Chen, Kyle Z. Pasquariello, Alice A. Gibson, James J. Petti, Shichen Shen +11 more

Data from Impact of ABCB1 Allelic Variants on QTc Interval Prolongation

(2023)10.1158/1078-0432.c.6518514.v1

N/A

0DataRank · unranked

0 citations

Erin R. Gardner, Richard Piekarz, Reuben Howden, Xiaohong Chen, Sukyung Woo +14 more

Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis

Journal of Chromatography B(2024)10.1016/j.jchromb.2024.124209

N/A

0DataRank · unranked

0 citations

Thomas Drabison, Yan Jin, Eric D. Eisenmann, Alex Sparreboom, Rajgopal Govindarajan +3 more

Drug–Drug Interaction Liabilities with BTK Inhibitor TL-895

Cancer Research Communications(2025)10.1158/2767-9764.crc-25-0265

N/A

0DataRank · unranked

1 citations

Eman Ahmed, Thomas Drabison, Mahesh R. Nepal, Anika T. Chowdhury, Shelley Orwick +6 more

Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors

Expert Review of Clinical Pharmacology(2025)10.1080/17512433.2025.2606258

N/A

0DataRank · unranked

0 citations

Anika T. Chowdhury, Kevin M. Huang, Shuiying Hu, Alex Sparreboom, Sharyn D. Baker +2 more

Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B

Molecules(2022)10.3390/molecules27206815

N/A

0DataRank · unranked

10 citations

Yan Jin, Zahra Talebi, Shuiying Hu, Alex Sparreboom, Sharyn D. Baker +2 more

Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice

Journal of Clinical Investigation(2020)10.1172/jci136796

N/A

0DataRank · unranked

69 citations

Alix F. Leblanc, Muhammad Erfan Uddin, JY Kim, Mingqing Chen, Eric D. Eisenmann +19 more

DNA Methylation‐Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia

Clinical and Translational Science(2020)10.1111/cts.12861

N/A

0DataRank · unranked

26 citations

Jason T. Anderson, Stanley Pounds, Lei Shi, Jatinder K. Lamba, Shuiying Hu +5 more

Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

Pharmaceutics(2020)10.3390/pharmaceutics12090856

N/A

0DataRank · unranked

48 citations

Zahra Talebi, Eric D. Eisenmann, Alex Sparreboom, Sharyn D. Baker, Dominique A. Garrison

A phase Ib study of the safety and pharmacology of nilotinib to prevent paclitaxel-induced peripheral neuropathy in patients with breast cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.tps12128

N/A

0DataRank · unranked

2 citations

Maryam B. Lustberg, Yan Jin, Yang Li, Alex Sparreboom, Shuiying Hu +1 more

Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-21-0071

N/A

0DataRank · unranked

45 citations

Xiyuan Lu, Zahra Talebi, Jae Yoon Jeon, Daelynn R. Buelow, Alice A. Gibson +13 more

Endogenous Biomarkers for SLC Transporter-Mediated Drug-Drug Interaction Evaluation

Molecules(2021)10.3390/molecules26185500

N/A

0DataRank · unranked

29 citations

Zahra Talebi, Xihui Chen, Alex Sparreboom, Shuiying Hu, Yang Li

In Vitro and In Vivo Inhibition of MATE1 by Tyrosine Kinase Inhibitors

Pharmaceutics(2021)10.3390/pharmaceutics13122004

N/A

0DataRank · unranked

23 citations

Zahra Talebi, Sijie Chen, Yan Jin, Alice A. Gibson, Anne M. Noonan +4 more

Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1

Frontiers in Pharmacology(2021)10.3389/fphar.2021.644342

N/A

0DataRank · unranked

22 citations

Dominique A. Garrison, Kyeongmin Kim, Yan Jin, Eric D. Eisenmann, Kevin M. Huang +5 more

Development, validation, and application of an LC-MS/MS method for the determination of the AXL/FLT3 inhibitor gilteritinib in mouse plasma

Journal of Chromatography B(2021)10.1016/j.jchromb.2021.122882

N/A

0DataRank · unranked

6 citations

Yan Jin, Muhammad Erfan Uddin, Alex Sparreboom, Sharyn D. Baker, Dominique A. Garrison

Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy

Nature Communications(2020)10.1038/s41467-020-14780-5

N/A

0DataRank · unranked

162 citations

Mario Vieweger, Kaiming Zhang, Hongran Yin, Hongzhi Wang, Xin Li +8 more

A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

Pharmaceutics(2022)10.3390/pharmaceutics14091933

N/A

0DataRank · unranked

7 citations

Yan Jin, Hanieh Taheri, Keith T. Schmidt, Alice A. Gibson, Stefan A.J. Buck +7 more

Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001466

N/A

0DataRank · unranked

8 citations

Yasuhiro Kazuki, Thomas Drabison, Kaoru Kobayashi, Ken‐ichi Fujita, Yue Xu +9 more

Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method

Heliyon(2023)10.1016/j.heliyon.2023.e20972

N/A

0DataRank · unranked

3 citations

Dominique A. Garrison, Eric D. Eisenmann, Kalindi Parmar, Geoffrey I. Shapiro, Michelle A. Rudek +3 more