🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Christina A. Castellani

Western University

ORCID: 0000-0003-2737-0549

Also affiliated with Children’s Health Research Institute

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs”.

Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

Genome Medicine(2020)10.1186/s13073-020-00778-7
N/A
3.0DataRank · unranked
123 citations

Ryan J. Longchamps, Jason A. Sumpter, Charles Newcomb, John Lane, Megan L. Grove +19 more

Evaluation of mitochondrial DNA copy number estimation techniques

PLoS ONE(2020)10.1371/journal.pone.0228166
N/A
0.760DataRank · unranked
158 citations

Christina A. Castellani, Stephanie Yang, Charles Newcomb, Jason A. Sumpter, John Lane +8 more

Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease

Genome Research(2021)10.1101/gr.269381.120
N/A
0.704DataRank · unranked
108 citations

Christina A. Castellani, Ryan J. Longchamps, Vamsee Pillalamarri, Brian O’Rourke, Eliseo Güallar +2 more

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

Human Genetics(2021)10.1007/s00439-021-02394-w
N/A
0.648DataRank · unranked
74 citations

Stephanie Yang, Christina A. Castellani, Wen Shi, Jon D. Lane, Megan L. Grove +47 more

Mitochondrial DNA copy number and incident atrial fibrillation

BMC Medicine(2020)10.1186/s12916-020-01715-6
N/A
0.557DataRank · unranked
40 citations

Traci M. Bartz, Nona Sotoodehnia, Wendy S. Post, Susan R. Heckbert, Álvaro Alonso +12 more

Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.17.209023
N/A
0.396DataRank · unranked
13 citations

Christina A. Castellani, Ryan J. Longchamps, Vamsee Pillalamarri, Brian O’Rourke, Eliseo Güallar +2 more

Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy

Nature Communications(2025)10.1038/s41467-025-65845-2
N/A
0.104DataRank · unranked
1 citations

Kyeezu Kim, Yinan Zheng, Christina A. Castellani, Scott M. Ratliff, Mengyao Wang +41 more

Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study

UNC Libraries(2024)10.17615/jcyb-0507
N/A
0DataRank · unranked
0 citations

L.R Loehr, Di Zhao, D.E Arking, Eliseo Güallar, E Boerwinkle +6 more

Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.10.687605
N/A
0DataRank · unranked
0 citations

Phyo W. Win, Charles Newcomb, Shaopeng Zeng, Christina A. Castellani, Dan E. Arking +1 more

Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

Epigenomics(2025)10.1080/17501911.2025.2603883
N/A
0DataRank · unranked
0 citations

Julia Nguyen, Elly H. Shin, Tyler Shin Nagano, Brent Selimi, Katie E. Hong +9 more

Thinking outside the nucleus: Mitochondrial DNA copy number in health and disease

Mitochondrion(2020)10.1016/j.mito.2020.06.004
N/A
0DataRank · unranked
367 citations

Ryan J. Longchamps, Jing Sun, Eliseo Güallar, Dan E. Arking, Christina A. Castellani

Genetic analysis of mitochondrial DNA copy number and associated traits identifies loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, and reveals a causal association of mitochondrial function with mortality

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.25.428086
N/A
0DataRank · unranked
8 citations

Stephanie Yang, Christina A. Castellani, Wen Shi, John Lane, ML Grove +47 more

Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.29.577835
N/A
0DataRank · unranked
2 citations

Phyo W. Win, Tyler Shin Nagano, Elly H. Shin, Charles Newcomb, Dan E. Arking +2 more