Ajith Karunarathne

ORCID: 0000-0003-3136-2015

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Subtype-dependent regulation of Gβγ signalling”.

Subtype-dependent regulation of Gβγ signalling

Cellular Signalling(2021)10.1016/j.cellsig.2021.109947

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53 citations

Kanishka Senarath, Dinesh Kankanamge, Kasun Ratnayake, Dhanushan Wijayaratna, Koshala Olupothage +5 more

Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100702

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43 citations

Sithurandi Ubeysinghe, Mithila Tennakoon, Priyanka D. Pantula, Kishalay Mitra, Lopamudra Giri +2 more

Molecular basis of sequence‐dependent differential prenylation inhibition and statin sensitivity of G proteins

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r6146

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0 citations

Ajith Karunarathne, Mithila Tennakoon

Molecular regulation of PLCβ signaling

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.01.001

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20 citations

Dhanushan Wijayaratna, Dinesh Kankanamge, Ajith Karunarathne, Sithurandi Ubeysinghe

The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics

Scientific Reports(2023)10.1038/s41598-023-29639-0

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11 citations

Kasun Ratnayake, Sithurandi Ubeysinghe, Dinesh Kankanamge, Mithila Tennakoon, Ajith Karunarathne +1 more

Spatiotemporal Optical Control of Gαq-PLCβ Interactions

ACS Synthetic Biology(2023)10.1021/acssynbio.3c00490

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9 citations

Dinesh Kankanamge, Waruna Thotamune, Dhanushan Wijayaratna, Thomas M. Mohan, Ajith Karunarathne +1 more

CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105269

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8 citations

Waruna Thotamune, John L. Payton, Ajith Karunarathne, Mithila Tennakoon

Engineered blue-shifted melanopsins for subcellular optogenetics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.07.561352

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1 citations

Filippo Sacchetta, Laura Pedraza‐González, Francesca Fanelli, Tomohiro Sugihara, Mitsumasa Koyanagi +7 more

Subcellular Optogenetic Inhibition of PLCβ-GαqGTP Interaction Sheds Light on the Molecular Regulation of Gαq-Governed Directional Cell Migration

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.544610

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0 citations

Dinesh Kankanamge, Ajith Karunarathne, Sithurand Ubeysinghe

Molecular regulation of G protein prenylation under sub-optimal conditions

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.558790

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0 citations

Mithila Tennakoon, Waruna Thotamune, John L. Payton, Ajith Karunarathne

Novel GαGTP Sensors to probe Subcellular signaling of Endogenous heterotrimeric G proteins

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.548930

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0 citations

Ajith Karunarathne, Dhanushan Wijayaratna

Spatiotemporal optical control of Gαq-PLCβ interactions

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.10.552801

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0 citations

Dinesh Kankanamge, Waruna Thotamune, Dhanushan Wijayaratna, Thomas M. Mohan, Ajith Karunarathne +1 more

In-silico predicted mouse melanopsins with blue spectral shifts deliver efficient subcellular signaling

Cell Communication and Signaling(2024)10.1186/s12964-024-01753-0

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5 citations

Filippo Sacchetta, Laura Pedraza‐González, Francesca Fanelli, Tomohiro Sugihara, Mitsumasa Koyanagi +7 more

A new light on PLCβ!

Cell chemical biology(2024)10.1016/j.chembiol.2024.06.007

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0 citations

Waruna Thotamune, Ajith Karunarathne, Sithurandi Ubeysinghe

3D Printed Transwell Microfluidic Devices for Epithelial Cell Culture with Shear Stress

ACS Measurement Science Au(2025)10.1021/acsmeasuresciau.5c00045

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2 citations

Cody Leasor, Waruna Thotamune, Ajith Karunarathne, Lane A. Baker, R. Scott Martin +1 more

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signalling and macrophage migration

Open Biology(2025)10.1098/rsob.240181

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1 citations

Sithurandi Ubeysinghe, Chathuri Rajarathna, Dinesh Kankanamge, Koshala Olupothage, Aditya Chandu +3 more

Recombinant–Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells

Chemical & Biomedical Imaging(2025)10.1021/cbmi.4c00067

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0 citations

Chloé Olayinka Sebilleau, Waruna Thotamune, Chathuri Rajarathna, Samuel Azibere, Mithila Tennakoon +6 more