David W. Hein

Biochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 31 papers. Top paper: “Identification and Characterization of Functional Rat Arylamine N-Acetyltransferase 3: Comparisons with Rat Arylamine N-Acetyltransferases 1 and 2”.

Identification and Characterization of Functional Rat Arylamine N-Acetyltransferase 3: Comparisons with Rat Arylamine N-Acetyltransferases 1 and 2

The Journal of Pharmacology and Experimental Therapeutics(2006)10.1124/jpet.106.108399

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1.5DataRank · unranked

34 citations

Mark A. Doll, David W. Hein, Jason M. Walraven

Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase

Carcinogenesis(1987)10.1093/carcin/8.12.1767

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1.4DataRank · unranked

31 citations

Thomas J. Flammang, Ward G. Kirlin, Alma Trinidad, Fredrick Ogolla, David W. Hein

Genetic polymorphism and cancer susceptibility: Evidence concerning acetyltransferases and cancer of the urinary bladder

BioEssays(1988)10.1002/bies.950090605

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1.1DataRank · unranked

11 citations

David W. Hein

Rabbit N-acetyltransferase 2 genotyping method to investigate role of acetylation polymorphism on N- and O-acetylation of aromatic and heterocyclic amine carcinogens

Archives of Toxicology(2017)10.1007/s00204-017-1997-7

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0.418DataRank · unranked

6 citations

Mark A. Doll, David W. Hein

Human Arylamine N-Acetyltransferase 1 (NAT1) Knockout in MDA-MB-231 Breast Cancer Cell Lines Leads to Transcription of NAT2

Frontiers in Pharmacology(2022)10.3389/fphar.2021.803254

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0.406DataRank · unranked

14 citations

Patrick J. Trainor, Mark A. Doll, David W. Hein, Samantha M. Carlisle

Proteomic analysis of arylamine N-acetyltransferase 1 knockout breast cancer cells: Implications in immune evasion and mitochondrial biogenesis

Toxicology Reports(2022)10.1016/j.toxrep.2022.07.010

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0.360DataRank · unranked

10 citations

Jonathan Q. Gardner, Mark A. Doll, Marcus W. Stepp, Daniel W. Wilkey, Frederick W. Benz +4 more

Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy

Clinical Pharmacology & Therapeutics(2025)10.1002/cpt.70071

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0.269DataRank · unranked

5 citations

David W. Hein, Michael Asger Andersen, Arlene B. Chapman, Rhonda M. Cooper‐DeHoff, Zeruesenay Desta +14 more

Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells

Genes(2023)10.3390/genes14040843

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0.241DataRank · unranked

4 citations

Xinmin Yin, Xipeng Ma, Xiang Zhang, David W. Hein, J. Wise

Influence of N ‐acetyltransferase polymorphism in the N ‐acetylation of asparagine and putrescine

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4723

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0.165DataRank · unranked

2 citations

David W. Hein, Raúl A. Salazar‐González

Acetyl coenzyme A kinetic studies on N-acetylation of environmental carcinogens by human N-acetyltransferase 1 and its NAT1*14B variant

Frontiers in Pharmacology(2022)10.3389/fphar.2022.931323

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0.165DataRank · unranked

2 citations

Mark A. Doll, David W. Hein, Mariam R. Habil

PharmVar GeneFocus : NAT2 — Genetic Variation and Updated Nomenclature

Clinical Pharmacology & Therapeutics(2025)10.1002/cpt.70168

N/A

0.165DataRank · unranked

2 citations

Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos +10 more

Changes in Insulin Signaling and Gluconeogenic Gene Expression in Human Hepatocytes Following Exposure to Heterocyclic Amines

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.02168

N/A

0.104DataRank · unranked

1 citations

Kyung U. Hong, David W. Hein, Kennedy M. Walls

Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells

Toxicology and Applied Pharmacology(2022)10.1016/j.taap.2022.115993

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0DataRank · unranked

3 citations

Raúl A. Salazar‐González, Mariam R. Habil, Mark A. Doll, David W. Hein, J. Wise

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

Archives of Toxicology(2023)10.1007/s00204-023-03508-1

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0DataRank · unranked

9 citations

Raúl A. Salazar‐González, Mark A. Doll, David W. Hein, Mariam R. Habil

Non-coding and intergenic genetic variants of human arylamine N-acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1091976

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0DataRank · unranked

9 citations

Kennedy M. Walls, David W. Hein, Kyung U. Hong

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

Toxicology Letters(2023)10.1016/j.toxlet.2023.07.002

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0DataRank · unranked

5 citations

Kyung U. Hong, David W. Hein, Kennedy M. Walls

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

Frontiers in Pharmacology(2024)10.3389/fphar.2024.1488367

N/A

0DataRank · unranked

2 citations

Anthony P. Aureliano, Kennedy M. Walls, David W. Hein, Kyung U. Hong

N-acetyltransferase metabolism and DNA damage following exposure to 4,4’-oxydianiline in human bronchial epithelial cells

Toxicology Letters(2024)10.1016/j.toxlet.2024.06.005

N/A

0DataRank · unranked

2 citations

David W. Hein, J. Wise

Metabolism and genotoxicity of 4,4’-oxydianiline is dependent on N-acetyltransferase 2 genetic polymorphism

Environmental Toxicology and Pharmacology(2025)10.1016/j.etap.2025.104699

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0DataRank · unranked

2 citations

J. Wise, Mark A. Doll, David W. Hein, Raúl A. Salazar‐González

Arylamine N-acetyltransferase 1 knockout in immortalized human bronchial cells results in a reduction of cellular growth

Gene Reports(2025)10.1016/j.genrep.2025.102332

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0DataRank · unranked

0 citations

Kate Tarvestad-Laise, David W. Hein, J. Wise, Sandra S Diven

Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2

Toxicology Reports(2020)10.1016/j.toxrep.2020.09.011

N/A

0DataRank · unranked

10 citations

Mark A. Doll, Angeliki Lykoudi, Raúl A. Salazar‐González, Mariam R. Habil, Kennedy M. Walls +6 more

Association between cigarette smoking and ovarian reserve among women seeking fertility care

PLoS ONE(2022)10.1371/journal.pone.0278998

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0DataRank · unranked

26 citations

T’shura Ali, David W. Hein, Kelly Pagidas, Henry Bohler, Mark A. Doll +8 more

Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT24, NAT25B or NAT2*7B N-acetyltransferase 2 haplotypes

Archives of Toxicology(2022)10.1007/s00204-022-03367-2

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0DataRank · unranked

16 citations

Raúl A. Salazar‐González, Mark A. Doll, David W. Hein, Mariam R. Habil

Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines

Toxicological Sciences(2022)10.1093/toxsci/kfac103

N/A

0DataRank · unranked

11 citations

Raúl A. Salazar‐González, Kennedy M. Walls, David W. Hein, Kyung U. Hong

N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

Archives of Toxicology(2022)10.1007/s00204-022-03383-2

N/A

0DataRank · unranked

9 citations

Mark A. Doll, David W. Hein, Raúl A. Salazar‐González

Arylamine N-Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status

Frontiers in Pharmacology(2022)10.3389/fphar.2022.797469

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0DataRank · unranked

9 citations

Mark A. Doll, David W. Hein, Raúl A. Salazar‐González

Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens

Frontiers in Pharmacology(2022)10.3389/fphar.2022.821133

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0DataRank · unranked

8 citations

Mark A. Doll, Mariam R. Habil, David W. Hein

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells

Journal of Cancer Research and Clinical Oncology(2022)10.1007/s00432-022-04436-w

N/A

0DataRank · unranked

7 citations

Afi Henriette Tagnedji, Mark A. Doll, Kennedy M. Walls, David W. Hein, Kyung U. Hong

Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells

Toxicology and Applied Pharmacology(2022)10.1016/j.taap.2022.116095

N/A

0DataRank · unranked

6 citations

Raúl A. Salazar‐González, Kennedy M. Walls, Mark A. Doll, Mariam R. Habil, David W. Hein +1 more

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes

Archives of Toxicology(2022)10.1007/s00204-022-03381-4

N/A

0DataRank · unranked

5 citations

Raúl A. Salazar‐González, Mark A. Doll, David W. Hein, Mariam R. Habil

560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment

Frontiers in Pharmacology(2022)10.3389/fphar.2022.820082

N/A

0DataRank · unranked

3 citations

David W. Hein, Mark A. Doll