William R. Jacobs

Also affiliated with University of Sheffield

MedicineEnvironmental ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 37 papers. Top paper: “Mycobacterium smegmatis: The Vanguard of Mycobacterial Research”.

Mycobacterium smegmatis: The Vanguard of Mycobacterial Research

Journal of Bacteriology(2023)10.1128/jb.00337-22

N/A

2.4DataRank · unranked

146 citations

Keith M. Derbyshire, William R. Jacobs, Yasu S Morita, Ian L. Sparks

3-(Phenethylamino)demethyl(oxy)aaptamine as an anti-dormant mycobacterial substance: Isolation, evaluation and total synthesis

Tetrahedron Letters(2020)10.1016/j.tetlet.2020.151924

N/A

0.817DataRank · unranked

18 citations

Naoyuki Kotoku, Chisu Han, Kentaro Kamiya, Andi Setiawan, Catherine Vilchèze +3 more

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

Molecular Microbiology(2002)10.1046/j.1365-2958.2002.03162.x

N/A

0.797DataRank · unranked

202 citations

Catherine Vilchèze, Laurent Kremer, Gurdyal S. Besra, Linda Parsons, Max Salfinger +6 more

Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates

Vaccine(2009)10.1016/j.vaccine.2009.05.050

N/A

0.704DataRank · unranked

108 citations

Karolin Biermann, Bing Chen, Tsungda Hsu, Vasan K. Sambandamurthy, Andrew A. Lackner +11 more

Vaccine Efficacy of a Lysine Auxotroph of Mycobacterium tuberculosis

Infection and Immunity(2003)10.1128/iai.71.7.4190-4192.2003

N/A

0.661DataRank · unranked

81 citations

Bing Chen, Cynthia L. Kelley, Frank M. Collins, William R. Jacobs, Martin S. Pavelka

Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis

Microbes and Infection(2005)10.1016/j.micinf.2005.04.001

N/A

0.631DataRank · unranked

66 citations

William R. Jacobs, Vasan K. Sambandamurthy

The Promises and Limitations of N -Acetylcysteine as a Potentiator of First-Line and Second-Line Tuberculosis Drugs

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.01703-20

N/A

0.464DataRank · unranked

21 citations

William R. Jacobs, Catherine Vilchèze

Capturing Structural Variants of Herpes Simplex Virus Genome in Full Length by Oxford Nanopore Sequencing

Microbiology Spectrum(2022)10.1128/spectrum.02285-22

N/A

0.330DataRank · unranked

8 citations

Emmanuel Asare, Lawrence W. Leung, Anna Paula de Oliveira, Katherine E. Kaugars, Claire V. Mulholland +4 more

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00644

N/A

0.269DataRank · unranked

5 citations

Hilda A. Namanja-Magliano, Rajagopalan Saranathan, Tanmay Mishra, Rodrigo G. Ducati, Brett M. Hirsch +8 more

Characterization of Large Deletion Mutants of Mycobacterium tuberculosis Selected for Isoniazid Resistance

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00792-20

N/A

0.269DataRank · unranked

5 citations

Rajagopalan Saranathan, Brian Weinrick, William R. Jacobs, Catherine Vilchèze

Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking of Mycobacterium leprae

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2508271122

N/A

0.169DataRank · unranked

2 citations

Bing Chen, Rajagopalan Saranathan, Catherine Vilchèze, Claire V. Mulholland, Michael Berney +5 more

Increased disease burden in Interleukin-3 deficient mice after Mycobacterium tuberculosis and herpes simplex virus infections

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.07.434271

N/A

0DataRank · unranked

0 citations

Tony W. Ng, Neeraj K. Saini, Michael F. Goldberg, Pooja Arora, Jiayong Xu +6 more

Commonalities of Mycobacterium tuberculosis Transcriptomes in Response to Defined Persisting Macrophage Stresses

Frontiers in Immunology(2022)10.3389/fimmu.2022.909904

N/A

0DataRank · unranked

26 citations

Bo Yan, Rosalyn Casey, Suzie Hingley‐Wilson, Laurence Ettwiller, William R. Jacobs +1 more

Loss of phenotypic inheritance associated with ydcI mutation leads to increased frequency of small, slow persisters in Escherichia coli

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1914741117

N/A

0DataRank · unranked

22 citations

Nan Ma, Yin Hu, Rosalyn Casey, Anders Bramming, Richard J. Curry +7 more

Mycobacterium tuberculosis Central Metabolism Is Key Regulator of Macrophage Pyroptosis and Host Immunity

Pathogens(2023)10.3390/pathogens12091109

N/A

0DataRank · unranked

3 citations

Lahari Das, Michael F. Goldberg, Steven A. Porcelli, John Chan, William R. Jacobs +1 more

The PDIM paradox of Mycobacterium tuberculosis : new solutions to a persistent problem

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.16.562559

N/A

0DataRank · unranked

7 citations

Thomas J. Wiggins, Jinhua Cui, Catherine Vilchèze, Rajagopalan Saranathan, Michael W. Shultis +4 more

Boosting bactericidal immunity of a recombinant Mycobacterium smegmatis strain via zinc-dependent ribosomal proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.11.571163

N/A

0DataRank · unranked

0 citations

David Kanzin, Sarah Chavez, Noemí Alejandra Saavedra-Ávila, Tony W. Ng, Regy Lukose +8 more

Propionate prevents loss of the PDIM virulence lipid in Mycobacterium tuberculosis

Nature Microbiology(2024)10.1038/s41564-024-01697-8

N/A

0DataRank · unranked

51 citations

Thomas J. Wiggins, Jinhua Cui, Catherine Vilchèze, Rajagopalan Saranathan, Michael W. Shultis +4 more

Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae438

N/A

0DataRank · unranked

9 citations

Amy K. Rourke, Emmanuel Asare, Donna Kohlerschmidt, Lahari Das, Senamile L. Ngema +14 more

A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus

Frontiers in Immunology(2024)10.3389/fimmu.2024.1429909

N/A

0DataRank · unranked

4 citations

Wakako Furuyama, Ariel S. Wirchnianski, Noemí Alejandra Saavedra-Ávila, Christopher T. Johndrow, Kartik Chandran +4 more

A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.28.595735

N/A

0DataRank · unranked

0 citations

Wakako Furuyama, Ariel S. Wirchnianski, Noemí Alejandra Saavedra-Ávila, Christopher T. Johndrow, Kartik Chandran +4 more

Boosting Immunogenicity of a Recombinant Mycobacterium smegmatis Strain via Zinc-Dependent Ribosomal Proteins

Biomedicines(2024)10.3390/biomedicines12071571

N/A

0DataRank · unranked

0 citations

David Kanzin, Sarah Chavez, Noemí Alejandra Saavedra-Ávila, Tony W. Ng, Regy Lukose +8 more

Loss of the ESX-5 secretion locus in Mycobacterium tuberculosis reshapes the mycomembrane and enhances ESX-1 substrate secretion

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2509997122

N/A

0DataRank · unranked

4 citations

Rajagopalan Saranathan, Courtney Schill, Shichun Lun, Catherine Vilchèze, Lahari Das +5 more

Luciferase reporter mycobacteriophage (TM4:: GeNL ) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex

Journal of Clinical Microbiology(2025)10.1128/jcm.00841-25

N/A

0DataRank · unranked

3 citations

Lahari Das, Donna Kohlerschmidt, Amy K. Rourke, Salika M. Shakir, Michelle H. Larsen +6 more

Loss of the PPE71-esxX-esxY-PPE38 locus drives adaptive transcriptional responses and hypervirulence of Mycobacterium tuberculosis Lineage 2

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.16.649112

N/A

0DataRank · unranked

2 citations

Courtney Schill, Rajagopalan Saranathan, Somnath Shee, Yazmin B. Martinez-Martinez, Manish Gupta +4 more

The unique role of nucS -mediated noncanonical mismatch repair in Mycobacterium tuberculosis resistance evolution

mBio(2025)10.1128/mbio.03310-25

N/A

0DataRank · unranked

0 citations

Jorge Sastre-Domínguez, José Ramón Valverde, Pablo García-Bravo, Ángel Ruiz-Enamorado, Rafael Prados-Rosales +6 more

The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions

Journal of Clinical Investigation(2023)10.1172/jci173156

N/A

0DataRank · unranked

27 citations

William R. Jacobs, William R. Bishai, Benjamin Koleske

A Single-Cycle Glycoprotein D Deletion Viral Vaccine Candidate, ΔgD-2, Elicits Polyfunctional Antibodies That Protect against Ocular Herpes Simplex Virus

Journal of Virology(2020)10.1128/jvi.00335-20

N/A

0DataRank · unranked

16 citations

Maria Luisa Visciano, Richard Hunte, Lip Nam Loh, Clare Burn Aschner, William R. Jacobs +2 more

Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette–Guérin Vaccination to Improve Antiviral Antibody Responses

The Journal of Immunology(2020)10.4049/jimmunol.2000191

N/A

0DataRank · unranked

10 citations

Ariel S. Wirchnianski, Anna Z. Wec, J. Maximilian Fels, Christopher T. Johndrow, Kevin O. Saunders +6 more

HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

Science Immunology(2020)10.1126/sciimmunol.aax2454

N/A

0DataRank · unranked

25 citations

Lip Nam Loh, Benjamin Galen, Isabel Delwel, Rohit K. Jangra, S. Garforth +6 more

BCG-Prime and boost with Esx-5 secretion system deletion mutant leads to better protection against clinical strains of Mycobacterium tuberculosis

Vaccine(2020)10.1016/j.vaccine.2020.08.004

N/A

0DataRank · unranked

23 citations

Taru S. Dutt, Bing Chen, Mei Chen, John Kim, Annie Z. Dai +12 more

Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated with Reduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques

UNC Libraries(2020)10.17615/r8wm-ak69

N/A

0DataRank · unranked

0 citations

Michael G. Hudgens, Koen K. A. Van Rompay, Kara Jensen, Kristina De Paris, Katie R. Mollan +10 more

A Recombinant Attenuated Mycobacterium tuberculosis Vaccine Strain Is Safe in Immunosuppressed Simian Immunodeficiency Virus-Infected Infant Macaques

UNC Libraries(2020)10.17615/7bh7-0t36

N/A

0DataRank · unranked

0 citations

Glenn J. Fennelly, Uma Devi Ranganathan, Kristina Abel, Paul A. Luciw, Resmi Ravindran +6 more

Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis

UNC Libraries(2020)10.17615/57ve-cf32

N/A

0DataRank · unranked

0 citations

Sunhee Lee, Randall J. Basaraba, Bing Chen, Manjunatha M. Venkataswamy, Steven A. Porcelli +8 more

A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis

Computational and Structural Biotechnology Journal(2021)10.1016/j.csbj.2021.06.006

N/A

0DataRank · unranked

26 citations

S.E. Thomas, Shaymaa A. Zaidan, Maria A. Pasillas, J. Cory-Wright, Víctor Sebastián-Pérez +10 more

Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

The Cell Surface(2021)10.1016/j.tcsw.2021.100060

N/A

0DataRank · unranked

12 citations

Luis Querales, Carlos Aranaga, Gustavo J. Lopez, Elba Guerrero, Laurent Kremer +12 more

Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis

mBio(2021)10.1128/mbio.02391-20

N/A

0DataRank · unranked

5 citations

Steven A. Porcelli, John Chan, William R. Jacobs, Catherine Vilchèze