Eric O. Freed

Also affiliated with National Cancer Institute, Center for Cancer Research

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 36 papers. Top paper: “Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle”.

Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle

Virologica Sinica(2019)10.1007/s12250-019-00095-3

N/A

2.8DataRank · unranked

92 citations

Yulan Zhang, Eric O. Freed, Ke Peng, Mariia Novikova

S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101112

N/A

2.1DataRank · unranked

58 citations

Cheng Man Lun, R. Elliot Murphy, Liam B. Healy, Géraldine Vilmen, Eric T. Christenson +3 more

HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly

Nature Structural & Molecular Biology(2023)10.1038/s41594-022-00887-4

N/A

1.4DataRank · unranked

60 citations

Alex B. Kleinpeter, Donna L. Mallery, Anna Albecka, K. M. Rifat Faysal, Till Böcking +4 more

Neutral sphingomyelinase 2 is required for HIV-1 maturation

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219475120

N/A

0.599DataRank · unranked

17 citations

Yanan Zhu, Eva L. Agostino, Lwar Naing, Yuta Hikichi, Ferri Soheilian +7 more

SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways

Science Signaling(2021)10.1126/scisignal.abc7611

N/A

0.464DataRank · unranked

21 citations

Abdül Waheed, Tianliang Li, Jingyou Yu, Yi-Min Zheng, Jacob S. Yount +3 more

Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity

Science Advances(2025)10.1126/sciadv.adv4356

N/A

0.312DataRank · unranked

6 citations

Yuta Hikichi, Juan S. Rey, Caner Akıl, Yanan Zhu, Hana Veler +5 more

Structural Basis of HIV-1 Maturation Inhibitor Binding and Activity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.22.481470

N/A

0.104DataRank · unranked

1 citations

Kaneil K. Zadrozny, Roman Zadorozhnyi, Ryan W. Russell, Caitlin M. Quinn, Alex B. Kleinpeter +9 more

The Vpu-interacting protein ATP6V0C regulates expression of tetherin and HIV-1 release

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.01.972125

N/A

0DataRank · unranked

0 citations

Maya Swiderski, Ali S. Khan, Ariana Gitzen, Ahlam Majadly, Eric O. Freed +1 more

Generation and validation of a highly sensitive bioluminescent HIV-1 reporter vector that simplifies measurement of virus release

Research Square(2020)10.21203/rs.3.rs-16277/v2

N/A

0DataRank · unranked

0 citations

Eric O. Freed, James Kirui

Generation and validation of a highly sensitive bioluminescent HIV-1 reporter vector that simplifies measurement of virus release

Research Square(2020)10.21203/rs.3.rs-16277/v3

N/A

0DataRank · unranked

0 citations

Eric O. Freed, James Kirui

Elucidation of the Molecular Consequences of Two Unique p6Gag Mutations Derived from HIV-1 CRF07_BC-infected Patients

Research Square (Research Square)(2020)10.21203/rs.2.21304/v1

N/A

0DataRank · unranked

0 citations

Sherimay D. Ablan, Eric O. Freed, Haiying Wang, Shixing Tang, Zetao Cheng

CryoET structures of immature HIV Gag reveal six-helix bundle

Communications Biology(2021)10.1038/s42003-021-01999-1

N/A

0DataRank · unranked

58 citations

Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek +9 more

Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

mBio(2021)10.1128/mbio.00219-21

N/A

0DataRank · unranked

50 citations

Abdul Waheed, Ahlam Majadly, Nicole Powell, Eric O. Freed, Cheng Man Lun

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

mBio(2021)10.1128/mbio.03134-20

N/A

0DataRank · unranked

40 citations

Rachel Van Duyne, Phuong Pham, Jennifer L. Groebner, Ann Wiegand, John W. Mellors +3 more

Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging

mBio(2021)10.1128/mbio.03254-21

N/A

0DataRank · unranked

25 citations

Steven Santos, Jian Chen, Matthew Brown, Olga A. Nikolaitchik, Sheldon Tai +5 more

Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.25.428025

N/A

0DataRank · unranked

4 citations

Abdül Waheed, Alhlam Majadly, Nicole Powell, Eric O. Freed, Cheng Man Lun

Rab11-FIP1C Is Dispensable for HIV-1 Replication in Primary CD4+T Cells, but Its Role Is Cell Type Dependent in Immortalized Human T-Cell Lines

Journal of Virology(2022)10.1128/jvi.00876-22

N/A

0DataRank · unranked

6 citations

Huxley K. Hoffman, Hannah M. Carter, Lacy M. Simons, Lwar Naing, Sherimay D. Ablan +5 more

Rab11-FIP1C is dispensable for HIV-1 replication in primary CD4 + T cells but its role is cell-type-dependent in immortalized human T-cell lines

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.03.494784

N/A

0DataRank · unranked

0 citations

Huxley K. Hoffman, Hannah Carter, Lacy M. Simons, Lwar Naing, Sherimay D. Ablan +4 more

Structural basis of HIV-1 maturation inhibitor binding and activity

Nature Communications(2023)10.1038/s41467-023-36569-y

N/A

0DataRank · unranked

30 citations

Kaneil K. Zadrozny, Roman Zadorozhnyi, Ryan W. Russell, Caitlin M. Quinn, Alex B. Kleinpeter +9 more

Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219543120

N/A

0DataRank · unranked

18 citations

Abdül Waheed, Pragney Deme, Şehmus Tohumeken, Rana Rais, Matthew D. Smith +7 more

The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168037

N/A

0DataRank · unranked

17 citations

Yanan Zhu, Donna L. Mallery, Sherimay D. Ablan, Long Chen, Nathan Hardenbrook +5 more

Guanylate-binding protein 5 antagonizes viral glycoproteins independently of furin processing

mBio(2024)10.1128/mbio.02086-24

N/A

0DataRank · unranked

15 citations

Cheng Man Lun, Abdul Waheed, Eric O. Freed, Hana Veler

Exploring HIV-1 Maturation: A New Frontier in Antiviral Development

Viruses(2024)10.3390/v16091423

N/A

0DataRank · unranked

14 citations

Grace Hillmer, Stefania M. Medehincu, Yuta Hikichi, Sophia Gagliardi, Kedhar Narayan +13 more

HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly

Nature Communications(2024)10.1038/s41467-024-51971-w

N/A

0DataRank · unranked

13 citations

Donna L. Mallery, Nadine Renner, Anna Albecka, J Ole Klarhof, Eric O. Freed +2 more

PSGL-1 excludes HIV Env from virion surface through spatial hindrance involving structural folding of the decameric repeats (DR)

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.28.630612

N/A

0DataRank · unranked

1 citations

Bryan M. Delfing, Han Yang, Christopher Lockhart, Amrita Haikerwal, Abdül Waheed +5 more

Structural Basis for HIV-1 Maturation Inhibition by PF-46396 Determined by MAS NMR

Journal of the American Chemical Society(2025)10.1021/jacs.5c08455

N/A

0DataRank · unranked

5 citations

Caitlin M. Quinn, Kaneil K. Zadrozny, Sherimay D. Ablan, Brandon J. Kennedy, Glenn P. A. Yap +8 more

IFN-inducible human phospholipid scramblase 1 (PLSCR1) protein restricts HIV-1 infection by inhibiting membrane fusion

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2516527122

N/A

0DataRank · unranked

4 citations

Pei Li, Yi-Min Zheng, Yuta Hikichi, Sherimay D. Ablan, Eric O. Freed +2 more

Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging

Nature Communications(2025)10.1038/s41467-025-63363-9

N/A

0DataRank · unranked

3 citations

Alex B. Kleinpeter, Juan S. Rey, Juan Shen, Y. Shen, Jialu Xu +7 more

Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.17.654662

N/A

0DataRank · unranked

1 citations

Ryan C. Burdick, Sean C. Patro, Si-Yuan Ding, Brian T. Luke, Erin Clark +5 more

Structural Basis for HIV-1 Maturation Inhibition by PF-46396 Determined by MAS NMR

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.15.664917

N/A

0DataRank · unranked

0 citations

Caitlin M. Quinn, Kaneil K. Zadrozny, Sherimay D. Ablan, Brandon J. Kennedy, Glenn P. A. Yap +8 more

HIV-1 Maturation: Lessons Learned from Inhibitors

Viruses(2020)10.3390/v12090940

N/A

0DataRank · unranked

101 citations

Eric O. Freed, Alex B. Kleinpeter

Generation and validation of a highly sensitive bioluminescent HIV-1 reporter vector that simplifies measurement of virus release

Retrovirology(2020)10.1186/s12977-020-00521-5

N/A

0DataRank · unranked

12 citations

Eric O. Freed, James Kirui

Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.05.008

N/A

0DataRank · unranked

4 citations

Holly Summers, Lola A. Brown, Jan Marchant, Paige N Canova, Colin O’Hern +10 more

PSGL-1 inhibits the virion incorporation of SARS-CoV and SARS-CoV-2 spike glycoproteins and impairs virus attachment and infectivity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.01.073387

N/A

0DataRank · unranked

12 citations

Abdül Waheed, Brian Hetrick, Deemah Dabbagh, Ivan Akhrymuk, Kylene Kehn-Hall +3 more

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.06.239350

N/A

0DataRank · unranked

2 citations

Rachel Van Duyne, Phuong Pham, Jennifer L. Groebner, Ann Wiegand, John W. Mellors +3 more

CryoET structures of immature HIV Gag reveal a complete six-helix bundle and stabilizing small molecules distinct from IP6

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.31.363382

N/A

0DataRank · unranked

1 citations

Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek +9 more