Dennie T. Frederick

Also affiliated with Massachusetts General Hospital

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

UNC Libraries(2020)10.17615/a8zp-dq08

Top 100%

0DataRank

Top 100%0 citations

Andrew E. Aplin, Yiling Lu, Sébastien Jeay, Carol L. Shields, Michal Barzily-Rokni +49 more

Papers

Driven by 38 papers — median percentile 0. Top paper: “Targeting TBK1 to overcome resistance to cancer immunotherapy”.

Targeting TBK1 to overcome resistance to cancer immunotherapy

Nature(2023)10.1038/s41586-023-05704-6

N/A

4.0DataRank · unranked

171 citations

Or‐Yam Revach, Seth Anderson, Emily Kessler, Clara Wolfe, Anne Jenney +54 more

Evolution of delayed resistance to immunotherapy in a melanoma responder

Nature Medicine(2021)10.1038/s41591-021-01331-8

N/A

3.6DataRank · unranked

137 citations

Jia‐Ren Lin, Emily Robitschek, Gyulnara G. Kasumova, Alex Heyde, Alvin Shi +35 more

Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

Nature Medicine(2024)10.1038/s41591-024-03040-4

N/A

2.1DataRank · unranked

107 citations

Minita Shah, Amanda Frydendahl, Daniel Halmos, Cole C. Khamnei, Nadia Øgaard +56 more

Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Science Advances(2020)10.1126/sciadv.abb3461

N/A

2.0DataRank · unranked

60 citations

Gyulnara G. Kasumova, William A. Michaud, Jessica Cintolo-Gonzalez, Marta Díaz-Martínez, Jacqueline Ohmura +13 more

Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition

Cancer Immunology Research(2022)10.1158/2326-6066.cir-21-0870

N/A

1.6DataRank · unranked

53 citations

Samuel C. Markson, Jackson H. Stocking, Naema Nayyar, Matt Lastrapes, Matthew R. Strickland +40 more

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Science(2016)10.1126/science.aad0501

N/A

1.3DataRank · unranked

5121 citations

Benjamin Izar, Sanjay M. Prakadan, Marc H. Wadsworth, Daniel Treacy, John J. Trombetta +39 more

Spatially organized multicellular immune hubs in human colorectal cancer

Cell(2021)10.1016/j.cell.2021.08.003

N/A

1.0DataRank · unranked

787 citations

Matan Hofree, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji, Alborz Bejnood +73 more

Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

Cell Reports Medicine(2022)10.1016/j.xcrm.2021.100500

N/A

0.972DataRank · unranked

35 citations

Moshe Sade-Feldman, Jaegil Kim, Chip Stewart, Anna Gonye, Arvind Ravi +34 more

Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma

Nature(2021)10.1038/s41586-021-03704-y

N/A

0.951DataRank · unranked

566 citations

Kari Stromhaug, Susan Klaeger, Tomasz Kula, Dennie T. Frederick, Phuong M. Le +21 more

Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses

Science Translational Medicine(2021)10.1126/scitranslmed.abd8636

N/A

0.691DataRank · unranked

99 citations

Masayoshi Kawakubo, Vikram R. Juneja, Mack Y. Su, Tal Hadad Erlich, Martin W. LaFleur +32 more

HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors

Nature Communications(2022)10.1038/s41467-022-31713-6

N/A

0.668DataRank · unranked

85 citations

Bin Wu, Ting Li, Lynn A. Beer, Gaurav Sharma, Mingyue Li +23 more

Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma

Nature Communications(2021)10.1038/s41467-021-26299-4

N/A

0.593DataRank · unranked

51 citations

Shiyou Wei, Zhi Wei, Dennie T. Frederick, Benchun Miao, Tabea Moll +10 more

Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-2773

N/A

0.574DataRank · unranked

45 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

Cancer Research(2021)10.1158/0008-5472.can-20-1496

N/A

0.489DataRank · unranked

25 citations

Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez +43 more

SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0291

N/A

0.457DataRank · unranked

20 citations

Bertrand Fabre, Yongmei Feng, Ali Khateb, Patrick Turko, Julia M. Martínez Gómez +19 more

Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma

Nature Communications(2025)10.1038/s41467-025-62878-5

N/A

0.438DataRank · unranked

13 citations

Cassia Wang, Doris Fu, Marcus Ho, Kyriakitsa Galani, Lee Chen +21 more

Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.17.476508

N/A

0.434DataRank · unranked

17 citations

Minita Shah, Nadia Øgaard, Cole C. Khamnei, Amanda Frydendahl, Aditya Deshpande +37 more

Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.03.450733

N/A

0.358DataRank · unranked

7 citations

Moshe Sade-Feldman, Jaegil Kim, Chip Stewart, Anna Gonye, Arvind Ravi +34 more

Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.17.516904

N/A

0.345DataRank · unranked

9 citations

Adam J. Widman, Anushri Arora, Itai Rusinek, William F. Hooper, Rebecca L. Murray +30 more

Characterizing the tumor and immune landscape of melanoma patients treated with combined checkpoint blockade and MAPK targeted therapy.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.9522

N/A

0.326DataRank · unranked

3 citations

Donald P. Lawrence, David F. McDermott, Mofei Liu, Elizabeth I. Buchbinder, Irena Gushterova +14 more

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.30.426796

N/A

0.297DataRank · unranked

4 citations

Matan Hofree, Jonathan Chen, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji +71 more

Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.02.478819

N/A

0.269DataRank · unranked

5 citations

Marijana Ručević, Emmett Sprecher, Milan Parikh, Jiajia Chen, Dennie T. Frederick +23 more

Plasma-derived exosomal analysis and deconvolution enables prediction and tracking of melanoma checkpoint blockade response

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/809699

N/A

0.219DataRank · unranked

2 citations

Gyulnara G. Kasumova, William A. Michaud, Jessica Cintolo-Gonzales, Marta Díaz Martínez, Jacqueline Ohmura +12 more

Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.20.599945

N/A

0.208DataRank · unranked

3 citations

Cassia Wang, Doris Fu, Marcus Ho, Kyriakitsa Galani, Lee Chen +14 more

Phylogenetic analysis of longitudinal melanoma samples to reveal convergent evolution and markers of immunotherapy resistance.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.9581

N/A

0.104DataRank · unranked

1 citations

Gao Zhang, Alvin Shi, Benjamin Izar, Alexander Heyde, Gyulnara G. Kasumova +14 more

Data from Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

(2023)10.1158/1078-0432.c.6529614

N/A

0DataRank · unranked

0 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Data from Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation

(2023)10.1158/1078-0432.c.6527784.v1

N/A

0DataRank · unranked

0 citations

Jenny Y. Xue, Dennie T. Frederick, Yi Cao, Eva Lin, Catherine Wilson +8 more

Data from Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

(2023)10.1158/1078-0432.c.6529614.v1

N/A

0DataRank · unranked

0 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0329

N/A

0DataRank · unranked

153 citations

Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera +17 more

Investigating the tumor immune infiltrate for populations that predict immune-related adverse events (irAEs) in patients receiving PD-1 inhibitors.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.3116

N/A

0DataRank · unranked

0 citations

Neal P. Smith, Moshe Sade-Feldman, Dennie T. Frederick, Russell W. Jenkins, Justine V. Cohen +13 more

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity

medRxiv(2025)10.1101/2025.09.19.25334095

N/A

0DataRank · unranked

0 citations

Pritha Sen, Christopher V. Cosgriff, Jessica Tantivit, Thomas Eisenhaure, Thomas J. LaSalle +61 more

Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2111173118

N/A

0DataRank · unranked

52 citations

Aaron S. Gajadhar, Bhavin Patel, Sébastien Gallien, Dennie T. Frederick, Genevieve M. Boland +3 more

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

UNC Libraries(2020)10.17615/a8zp-dq08

Top 100%

0DataRank

Top 100%0 citations

Andrew E. Aplin, Yiling Lu, Sébastien Jeay, Carol L. Shields, Michal Barzily-Rokni +49 more

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.25.456956

N/A

0DataRank · unranked

0 citations

Samuel C. Markson, Jackson H. Stocking, Naema Nayyar, Matthew Lastrapes, Matthew R. Strickland +39 more

Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth

Nature Metabolism(2022)10.1038/s42255-022-00676-9

N/A

0DataRank · unranked

165 citations

Da Teng, Lifeng Yang, Xincheng Xu, Jiajia Chen, Teng‐Jia Jiang +14 more

Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy

(2025)10.1101/2025.10.31.25338685

N/A

0DataRank · unranked

0 citations

Dennie T. Frederick, Alvin Shi, Ana B. Larque, Benchun Miao, Tatyana Sharova +16 more

STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming

Nature Communications(2022)10.1038/s41467-022-29541-9

N/A

0DataRank · unranked

45 citations

Lei Gu, Yeguang Hu, Xiaoyang Zhang, Man Li, Jiajia Chen +20 more

MAESTRO-Pool Enables Highly Parallel and Specific Mutation-Enrichment Sequencing for Minimal Residual Disease Detection in Cohort Studies

Clinical Chemistry(2023)10.1093/clinchem/hvad203

N/A

0DataRank · unranked

11 citations

Justin Rhoades, Ruolin Liu, Kan Xiong, Sainetra Sridhar, Andjela Crnjac +7 more

Dennie T. Frederick

Indexed papers

Top data-sharing exemplar

Papers