Mingzhen Zhang

Also affiliated with Jiangsu Province Hospital, Nanjing Medical University, Xi'an Jiaotong University

Biochemistry, Genetics and Molecular BiologyMedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 28 papers. Top paper: “PI3K inhibitors: review and new strategies”.

PI3K inhibitors: review and new strategies

Chemical Science(2020)10.1039/d0sc01676d

N/A

0.787DataRank · unranked

189 citations

Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK

Biophysical Reviews(2023)10.1007/s12551-023-01054-9

N/A

0.596DataRank · unranked

52 citations

Bengi Ruken Yavuz, M. Kaan Arici, Habibe Cansu Demirel, Mingzhen Zhang, Yonglan Liu +4 more

Structural Features that Distinguish Inactive and Active PI3K Lipid Kinases

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.09.002

N/A

0.581DataRank · unranked

47 citations

Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

The mechanism of activation of MEK1 by B-Raf and KSR1

Cellular and Molecular Life Sciences(2022)10.1007/s00018-022-04296-0

N/A

0.553DataRank · unranked

39 citations

Mingzhen Zhang, Yonglan Liu, Hyunbum Jang, Ruth Nussinov, Ryan Maloney

Nuclear Exportin 1 (XPO1) Binds to the Nuclear Localization/Export Signal of the Turnip Mosaic Virus NIb to Promote Viral Infection

Frontiers in Microbiology(2022)10.3389/fmicb.2021.780724

N/A

0.483DataRank · unranked

11 citations

Pan Gong, Linhao Ge, Yinzi Li, Zhaoyang Chang, Rui Qiao +4 more

The structural basis of BCR-ABL recruitment of GRB2 in chronic myelogenous leukemia

Biophysical Journal(2022)10.1016/j.bpj.2022.05.030

N/A

0.477DataRank · unranked

23 citations

Hyunbum Jang, Mingzhen Zhang, Chung‐Jung Tsai, Ryan Maloney, Ruth Nussinov +1 more

Spatial Mechano‐Signaling Regulation of GTPases through Non‐Degradative Ubiquitination

Advanced Science(2023)10.1002/advs.202303367

N/A

0.464DataRank · unranked

21 citations

Paolo Carai, Tonči Ivanišević, Mingzhen Zhang, Hyunbum Jang, Benoit Lechat +6 more

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins

The EMBO Journal(2024)10.1038/s44318-024-00146-w

N/A

0.434DataRank · unranked

17 citations

Mikhail Steklov, Hyunbum Jang, Raj Nayan Sewduth, Amir Florentin, Benoit Lechat +7 more

Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family

Familial Cancer(2021)10.1007/s10689-021-00267-9

N/A

0.241DataRank · unranked

4 citations

Mai Xu, Michael R. Sargen, Hyunbum Jang, Mingzhen Zhang, Tongwu Zhang +24 more

Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family

medRxiv(2021)10.1101/2021.04.20.21254596

N/A

0.104DataRank · unranked

1 citations

Mai Xu, Michael R. Sargen, Hyunbum Jang, Mingzhen Zhang, Tongwu Zhang +24 more

Ras isoform-specific expression, chromatin accessibility, and signaling

Biophysical Reviews(2021)10.1007/s12551-021-00817-6

N/A

0DataRank · unranked

26 citations

Mingzhen Zhang, Ryan Maloney, Hyunbum Jang, Ruth Nussinov

Drugging multiple same-allele driver mutations in cancer

Expert Opinion on Drug Discovery(2021)10.1080/17460441.2021.1905628

N/A

0DataRank · unranked

14 citations

Mingzhen Zhang, Ryan Maloney, Hyunbum Jang, Ruth Nussinov

Allostery: Allosteric Cancer Drivers and Innovative Allosteric Drugs

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167569

N/A

0DataRank · unranked

69 citations

Mingzhen Zhang, Ryan Maloney, Yonglan Liu, Chung‐Jung Tsai, Hyunbum Jang +1 more

PI3K Driver Mutations: A Biophysical Membrane-Centric Perspective

Cancer Research(2020)10.1158/0008-5472.can-20-0911

N/A

0DataRank · unranked

42 citations

Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

Allosteric regulation of autoinhibition and activation of c-Abl

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.08.014

N/A

0DataRank · unranked

32 citations

Mingzhen Zhang, Chung‐Jung Tsai, Hyunbum Jang, Ruth Nussinov, Yonglan Liu

Higher‐order interactions of Bcr‐Abl can broaden chronic myeloid leukemia (CML) drug repertoire

Protein Science(2022)10.1002/pro.4504

N/A

0DataRank · unranked

20 citations

Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov, Yonglan Liu

Activation mechanisms of clinically distinct B‐Raf V600E and V600K mutants

Cancer Communications(2022)10.1002/cac2.12395

N/A

0DataRank · unranked

13 citations

Ryan Maloney, Yonglan Liu, Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

The Mechanism of Activation of MEK1 by B-Raf and KSR1

Research Square(2022)10.21203/rs.3.rs-1412459/v1

N/A

0DataRank · unranked

0 citations

Mingzhen Zhang, Yonglan Liu, Hyunbum Jang, Ruth Nussinov, Ryan Maloney

AlphaFold, allosteric, and orthosteric drug discovery: Ways forward

Drug Discovery Today(2023)10.1016/j.drudis.2023.103551

N/A

0DataRank · unranked

93 citations

Mingzhen Zhang, Yonglan Liu, Hyunbum Jang, Ruth Nussinov

Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0818

N/A

0DataRank · unranked

45 citations

Mingzhen Zhang, Chung‐Jung Tsai, Hyunbum Jang, Ruth Nussinov

Strategy toward Kinase-Selective Drug Discovery

Journal of Chemical Theory and Computation(2023)10.1021/acs.jctc.2c01171

N/A

0DataRank · unranked

32 citations

Yonglan Liu, Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

The allosteric mechanism of mTOR activation can inform bitopic inhibitor optimization

Chemical Science(2023)10.1039/d3sc04690g

N/A

0DataRank · unranked

24 citations

Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov, Yonglan Liu

The Mystery of Rap1 Suppression of Oncogenic Ras

Trends in cancer(2020)10.1016/j.trecan.2020.02.002

N/A

0DataRank · unranked

39 citations

Hyunbum Jang, Mingzhen Zhang, Chung‐Jung Tsai, Anna Sablina, Ruth Nussinov

RAS Signaling in the PI3K/AKT/MTOR Pathway

Biophysical Journal(2020)10.1016/j.bpj.2019.11.458

N/A

0DataRank · unranked

5 citations

Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov

The mechanism of activation of monomeric B-Raf V600E

Computational and Structural Biotechnology Journal(2021)10.1016/j.csbj.2021.06.007

N/A

0DataRank · unranked

83 citations

Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov, Ryan Maloney

The mechanism of Raf activation through dimerization

Chemical Science(2021)10.1039/d1sc03444h

N/A

0DataRank · unranked

57 citations

Ryan Maloney, Hyunbum Jang, Ruth Nussinov, Mingzhen Zhang

B-Raf autoinhibition in the presence and absence of 14-3-3

Structure(2021)10.1016/j.str.2021.02.005

N/A

0DataRank · unranked

54 citations

Hyunbum Jang, Zhigang Li, David B. Sacks, Ruth Nussinov, Mingzhen Zhang

Mechanism of activation and the rewired network: New drug design concepts

Medicinal Research Reviews(2021)10.1002/med.21863

N/A

0DataRank · unranked

30 citations

Mingzhen Zhang, Ryan Maloney, Chung‐Jung Tsai, Bengi Ruken Yavuz, Nurcan Tunçbağ +2 more