Nicholas C. Zachos

Also affiliated with Johns Hopkins Medicine

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Optimizing Human Intestinal Enteroids for Environmental Monitoring of Human Norovirus”.

Optimizing Human Intestinal Enteroids for Environmental Monitoring of Human Norovirus

Food and Environmental Virology(2021)10.1007/s12560-021-09486-w

N/A

0.869DataRank · unranked

19 citations

Nicholas C. Zachos, Caroline Coulter, Kellogg J. Schwab, Katie Overbey

Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli

Scientific Reports(2020)10.1038/s41598-020-67104-4

N/A

0.619DataRank · unranked

61 citations

Waleska Saitz-Rojas, Rachel Smith, Laura A. Gonyar, Julie In, Olga Kovbasnjuk +5 more

Flagellin-specific human CAR Tregs for immune regulation in IBD

Journal of Autoimmunity(2022)10.1016/j.jaut.2022.102961

N/A

0.593DataRank · unranked

51 citations

May Q. Wong, William D. Rees, Dan Wu, Megan E. Himmel, Paul C. Orban +5 more

Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin‐induced colon epithelial cell signaling

The FASEB Journal(2020)10.1096/fj.202001669r

N/A

0.524DataRank · unranked

32 citations

Jawara Allen, Isabella Posey, Jeremy J.P. Shaw, Pedro Costa‐Pinheiro, Susan J. Walker +8 more

Aggregative Adherence Fimbriae II of Enteroaggregative Escherichia coli Are Required for Adherence and Barrier Disruption during Infection of Human Colonoids

Infection and Immunity(2020)10.1128/iai.00176-20

N/A

0.500DataRank · unranked

27 citations

Rachel M. Smith, Jorge A. Girón, Nicholas C. Zachos, Fernando Ruı́z-Pérez, James P. Nataro +1 more

An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers

Cell Reports(2022)10.1016/j.celrep.2021.110283

N/A

0.434DataRank · unranked

17 citations

Nikita Telkar, David T. S. Lin, May Q. Wong, Chad Poloni, Ayda Fathi +4 more

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function

Cellular and Molecular Gastroenterology and Hepatology(2021)10.1016/j.jcmgh.2021.08.010

N/A

0DataRank · unranked

82 citations

Kelli Johnson, Jianyi Yin, Sun Lee, Ruxian Lin, Huimin Yu +6 more

Recovery of Infectious Human Norovirus GII.4 Sydney From Fomites via Replication in Human Intestinal Enteroids

Frontiers in Cellular and Infection Microbiology(2021)10.3389/fcimb.2021.693090

N/A

0DataRank · unranked

6 citations

Nicholas C. Zachos, Caroline Coulter, Joseph G. Jacangelo, Kellogg J. Schwab, Katie Overbey

Chronic inflammation in ulcerative colitis causes long term changes in gobletcell function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.17.435871

N/A

0DataRank · unranked

8 citations

Kelli Johnson, Jianyi Yin, Sunny Lee, Ruxian Lin, Helen Yu +4 more

SARS-COV-2 induced Diarrhea is inflammatory, Ca 2+ Dependent and involves activation of calcium activated Cl channels

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.27.441695

N/A

0DataRank · unranked

1 citations

Chung-Ming Tse, Karol Dokładny, Manmeet Rawat, Ivy Horwitz, Chunyan Ye +12 more

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.23.457340

N/A

0DataRank · unranked

0 citations

Gaya S. Dasanayake, Mary K. Estes, Nicholas C. Zachos, David T. Breault, Ralph R. Isberg +3 more

Epithelial and Neutrophil Interactions and Coordinated Response toShigellain a Human Intestinal Enteroid-Neutrophil Coculture Model

mBio(2022)10.1128/mbio.00944-22

N/A

0DataRank · unranked

28 citations

Michèle Doucet, Nicholas C. Zachos, Marcela F. Pasetti, Jose M. Lemme‐Dumit

In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice

Nature Biotechnology(2023)10.1038/s41587-022-01558-x

N/A

0DataRank · unranked

119 citations

Kathryn A. Wikenheiser‐Brokamp, Praneet Chaturvedi, Nambirajan Sundaram, Gillian R. Goddard, Mark Wunderlich +15 more

Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis

Science Immunology(2023)10.1126/sciimmunol.abp9940

N/A

0DataRank · unranked

35 citations

Jessica L. Kinard, Jenny Min Li, Ian N. Moore, Justin Lack, Elizabeth R. Fischer +11 more

Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids

STAR Protocols(2023)10.1016/j.xpro.2023.102335

N/A

0DataRank · unranked

3 citations

Katlynn Bugda Gwilt, Stefanie S. Schmieder, Nicholas C. Zachos, Wayne I. Lencer, Keiko Maeda

A Novel Peptide Prevents Enterotoxin- and Inflammation-Induced Intestinal Fluid Secretion by Stimulating Sodium-Hydrogen Exchanger 3 Activity

Gastroenterology(2023)10.1053/j.gastro.2023.06.028

N/A

0DataRank · unranked

3 citations

Hannah J. Vaughan, Ruxian Lin, Rafiquel Sarker, Savannah Est‐Witte, Molee Chakraborty +8 more

COVID-19 Diarrhea Is Inflammatory, Caused by Direct Viral Effects Plus Major Role of Virus-induced Cytokines

Cellular and Molecular Gastroenterology and Hepatology(2024)10.1016/j.jcmgh.2024.101383

N/A

0DataRank · unranked

1 citations

Chung-Ming Tse, Rafiq Sarker, Ruxian Lin, Karol Dokładny, Manmeet Rawat +18 more

Current and potential future applications of human stem cell models in drug development

Journal of Clinical Investigation(2020)10.1172/jci138645

N/A

0DataRank · unranked

20 citations

Jerrold R. Turner, A.S. Verkman, Nicholas C. Zachos, Mark Donowitz

Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

Molecular Metabolism(2020)10.1016/j.molmet.2020.101129

N/A

0DataRank · unranked

34 citations

Kelli Johnson, Jianyi Yin, Nicholas W. Baetz, Lea Fayad, Vadim Sherman +6 more

Coronin-1 is necessary for enteric pathogen-induced transcytosis across human ileal enteroid monolayers expressing M cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.12.305565

N/A

0DataRank · unranked

4 citations

Michèle Doucet, Rachel Latanich, Sun Lee, Mary K. Estes, James B. Kaper +2 more

Epithelial and neutrophil interactions and coordinated response to Shigella in a human intestinal enteroid-neutrophil co-culture model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.03.281535

N/A

0DataRank · unranked

2 citations

Michele Doucet, Nicholas C. Zachos, Marcela F. Pasetti, Jose M. Lemme-Dumit

Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism

UNC Libraries(2020)10.17615/4dvc-1y89

N/A

0DataRank · unranked

0 citations

Boyoung Cha, William R. Thelin, Xuhang Li, Nicholas C. Zachos, Caleb A. Hodson +3 more