Brian T. Chait

ChemistryImmunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 62 papers. Top paper: “Comprehensive structure and functional adaptations of the yeast nuclear pore complex”.

Comprehensive structure and functional adaptations of the yeast nuclear pore complex

Cell(2022)10.1016/j.cell.2021.12.015

N/A

4.2DataRank · unranked

191 citations

Digvijay Singh, Christna Ouch, Ignacia Echeverria, Ilona Nudelman, Joseph M. Varberg +18 more

Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0313

N/A

1.7DataRank · unranked

85 citations

Connie Wu, Peter C. Fridy, Stephanie J. Zhang, Yasmeen Senussi, Justina C. Wolters +54 more

The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity

Science(1998)10.1126/science.280.5360.69

N/A

1.3DataRank · unranked

6799 citations

João Morais Cabral, Richard A. Pfuetzner, Anling Kuo, Jacqueline M. Gulbis, Steven L. Cohen +5 more

Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex

The Journal of Cell Biology(2001)10.1083/jcb.153.7.1465

N/A

0.772DataRank · unranked

171 citations

Adisetyantari Suprapto, Julio C. Padovan, Brian T. Chait, Richard W. Wozniak, Michael P. Rout +2 more

Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.08.194084

N/A

0.581DataRank · unranked

47 citations

Brandon Malone, Eliza Llewellyn, Michael Grasso, Patrick M. M. Shelton, Paul Dominic B. Olinares +8 more

Shelterin is a dimeric complex with extensive structural heterogeneity

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2201662119

N/A

0.578DataRank · unranked

46 citations

Paul Dominic B. Olinares, Vladimir Svetlov, Martin Bush, Evgeny Nudler, Brian T. Chait +3 more

Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function

The Journal of Cell Biology(2021)10.1083/jcb.202009146

N/A

0.546DataRank · unranked

37 citations

Shih-Chieh Ti, L. Urnavicius, Kelly R. Molloy, Amol Aher, Brian T. Chait +2 more

Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM

Structure(2020)10.1016/j.str.2020.11.001

N/A

0.529DataRank · unranked

33 citations

Jin Young Kang, Eliza Llewellyn, Courtney Chiu, James Chen, Brandon Malone +5 more

Affinity proteomic dissection of the human nuclear cap-binding complex interactome

Nucleic Acids Research(2020)10.1093/nar/gkaa743

N/A

0.524DataRank · unranked

32 citations

Svetlana Kalmykova, Maria Pashkova, Mehrnoosh Oghbaie, Hua Jiang, Kelly R. Molloy +7 more

KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid

Nature Microbiology(2025)10.1038/s41564-024-01915-3

N/A

0.406DataRank · unranked

14 citations

Francisco de Asís Balaguer, Joshua Chandanani, Christopher M. Thomas, Clara Aicart-Ramos, Sophia Burick +10 more

Comprehensive Structure and Functional Adaptations of the Yeast Nuclear Pore Complex

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.29.466335

N/A

0.406DataRank · unranked

14 citations

Digvijay Singh, Christna Ouch, Ignacia Echeverria, Ilona Nudelman, Joseph M. Varberg +18 more

A new generation of nanobody research tools using improved mass spectrometry-based discovery methods

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107623

N/A

0.385DataRank · unranked

12 citations

Ryan Farrell, Kelly R. Molloy, Sarah Keegan, Junjie Wang, Erica Y. Jacobs +8 more

Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.16.579611

N/A

0.344DataRank · unranked

6 citations

Francisco de Asís Balaguer, Joshua Chandanani, Christopher M. Thomas, Clara Aicart-Ramos, Sophia Burick +10 more

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.09.593355

N/A

0.312DataRank · unranked

7 citations

Donna Garvey Brickner, Kara Zehr, Jake VanBelzen, Wenzhu Zhang, Christopher A. Caffalette +6 more

Structural study on human microbiome-derived polyketide synthases that assemble genotoxic colibactin

Structure(2025)10.1016/j.str.2025.04.017

N/A

0.269DataRank · unranked

5 citations

Jinwoo Kim, Gyu Sung Lee, Paul Dominic B. Olinares, Yougant Airan, Jasmine L. Chow +8 more

Distinct Quaternary States, Intermediates, and Autoinhibition During Loading of the DnaB-Replicative Helicase by the Phage λP Helicase Loader

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.30.522210

N/A

0.165DataRank · unranked

2 citations

Dhanjai Brown, Paul Dominic B. Olinares, Jillian Chase, Eta A. Isiorho, Brian T. Chait +2 more

Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

eLife(2023)10.7554/elife.89423

N/A

0.165DataRank · unranked

2 citations

Fred D. Mast, Peter C. Fridy, Jean Paul Olivier, Tanmoy Sanyal, Andrej Săli +4 more

Measuring in vivo protein turnover and exchange in yeast macromolecular assemblies

STAR Protocols(2021)10.1016/j.xpro.2021.100800

N/A

0DataRank · unranked

6 citations

Kelly R. Molloy, Roman I. Subbotin, Javier Fernández-Martı́nez, Brian T. Chait, Michael P. Rout +1 more

Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.13.435256

N/A

0DataRank · unranked

27 citations

James Chen, Qi Wang, Eliza Llewellyn, Young Joo Choi, Paul Dominic B. Olinares +9 more

Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape

eLife(2021)10.7554/elife.73027

N/A

0DataRank · unranked

71 citations

Peter C. Fridy, Natalia E. Ketaren, Junjie Wang, Erica Y. Jacobs, Jean Paul Olivier +24 more

Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.08.438911

N/A

0DataRank · unranked

10 citations

Peter C. Fridy, Natalia E. Ketaren, Junjie Wang, Erica Y. Jacobs, Jean Paul Olivier +23 more

The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.30.458255

N/A

0DataRank · unranked

0 citations

Paul Dominic B. Olinares, Brian T. Chait, Shixin Liu, Tarun M. Kapoor, Keith J. Mickolajczyk

Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2102516118

N/A

0DataRank · unranked

127 citations

James Chen, Qi Wang, Eliza Llewellyn, Young Joo Choi, Paul Dominic B. Olinares +9 more

Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA

UNC Libraries(2020)10.17615/68de-g186

N/A

0DataRank · unranked

0 citations

Thomas Shenk, Nathaniel J. Moorman, Brian T. Chait, Christian Cuevas, Scott S. Terhune +3 more

Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101882

N/A

0DataRank · unranked

27 citations

Yael Udi, Milana E. Stein, Valay Patel, Peter C. Fridy, Charles M. Rice +5 more

Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA

Nature Communications(2022)10.1038/s41467-022-32315-y

N/A

0DataRank · unranked

18 citations

Paul Dominic B. Olinares, Jimin Lee, Jinwoo Kim, Brian T. Chait, Rodney A. King +2 more

Structural basis for substrate selection by the SARS-CoV-2 replicase

Nature(2023)10.1038/s41586-022-05664-3

N/A

0DataRank · unranked

87 citations

Jason K. Perry, Paul Dominic B. Olinares, Hery W. Lee, James Chen, T.C. Appleby +14 more

Affinity proteomic dissection of the human nuclear cap-binding complex interactome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.048470

N/A

0DataRank · unranked

2 citations

Svetlana Kalmykova, Maria Pashkova, Mehrnoosh Oghbaie, Hua Jiang, Kelly R. Molloy +7 more

Implications of a multiscale structure of the yeast nuclear pore complex

Molecular Cell(2023)10.1016/j.molcel.2023.08.025

N/A

0DataRank · unranked

26 citations

Ignacia Echeverria, Christna Ouch, Ilona Nudelman, Yi Shi, Junjie Wang +5 more

Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102954

N/A

0DataRank · unranked

23 citations

Peter C. Fridy, Natalia E. Ketaren, Fred D. Mast, Song Li, Jean Paul Olivier +5 more

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain

Molecular Cell(2023)10.1016/j.molcel.2023.10.001

N/A

0DataRank · unranked

22 citations

Olga Fedorova, Paul Dominic B. Olinares, Joshua Chandanani, Anoosha Banerjee, Young Joo Choi +5 more

Immunodominant surface epitopes power immune evasion in the African trypanosome

Cell Reports(2023)10.1016/j.celrep.2023.112262

N/A

0DataRank · unranked

14 citations

Francisco Aresta‐Branco, Gianna Triller, Evi P. Vlachou, Monique van Straaten, Mirjana Lilić +9 more

A nucleotide binding–independent role for γ-tubulin in microtubule capping and cell division

The Journal of Cell Biology(2023)10.1083/jcb.202204102

N/A

0DataRank · unranked

14 citations

Michał W. Wieczorek, Amol Aher, Paul Dominic B. Olinares, Brian T. Chait, Tarun M. Kapoor +1 more

A general method for quantitative fractionation of mammalian cells

The Journal of Cell Biology(2023)10.1083/jcb.202209062

N/A

0DataRank · unranked

10 citations

Wenzhu Zhang, Milana E. Stein, Inna Ricardo-Lax, H. Amalia Pasolli, Brian T. Chait +2 more

Dynamic molecular mechanism of the nuclear pore complex permeability barrier

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.31.535055

N/A

0DataRank · unranked

26 citations

Javier Fernández-Martı́nez, Trevor van Eeuwen, Paola Gallardo, Larisa E. Kapinos, Artur Mazur +11 more

Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.02.543478

N/A

0DataRank · unranked

3 citations

John W. Watters, Paul Dominic B. Olinares, Joshua A. Luo, Brian T. Chait, Shixin Liu +1 more

Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

(2023)10.7554/elife.89423.1

N/A

0DataRank · unranked

2 citations

Fred D. Mast, Peter C. Fridy, Jean Paul Olivier, Tanmoy Sanyal, Andrej Săli +4 more

Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.14.549041

N/A

0DataRank · unranked

1 citations

Fred D. Mast, Peter C. Fridy, Jean Paul Olivier, Tanmoy Sanyal, Andrej Săli +4 more

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.25.558837

N/A

0DataRank · unranked

1 citations

Olga Fedorova, Paul Dominic B. Olinares, Joshua Chandanani, Anoosha Banerjee, Young Joo Choi +5 more

Using a function-first ‘scout fragment’-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.25.559391

N/A

0DataRank · unranked

1 citations

Patrick M. M. Shelton, Tyler K. Heiss, Paul Dominic B. Olinares, Lauren E. Vostal, Heather Soileau +11 more

The molecular architecture of the nuclear basket

Cell(2024)10.1016/j.cell.2024.07.020

N/A

0DataRank · unranked

86 citations

Neelesh Soni, Joshua Hutchings, Ignacia Echeverria, Farhaz Shaikh, Madeleine Duquette +13 more

Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA

Nature Structural & Molecular Biology(2024)10.1038/s41594-024-01373-9

N/A

0DataRank · unranked

13 citations

John W. Watters, Paul Dominic B. Olinares, Masuda Begum, Lauren E. Vostal, Joshua A. Luo +3 more

Structural basis for transcription complex disruption by the Mfd translocase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.12.248500

N/A

0DataRank · unranked

6 citations

Eliza Llewellyn, James Chen, Paul Dominic B. Olinares, Joshua J. Brewer, Brian T. Chait +3 more

A lineage-specific protein network at the trypanosome nuclear envelope

Nucleus(2024)10.1080/19491034.2024.2310452

N/A

0DataRank · unranked

10 citations

Samson O. Obado, Simon R. Scutts, Wenzhu Zhang, Brian T. Chait, Michael P. Rout +2 more

Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

eLife(2024)10.7554/elife.89423.3

N/A

0DataRank · unranked

5 citations

Fred D. Mast, Peter C. Fridy, Jean Paul Olivier, Tanmoy Sanyal, Andrej Săli +4 more

Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality

The Journal of Cell Biology(2020)10.1083/jcb.202006159

N/A

0DataRank · unranked

28 citations

Arti T. Navare, Almer M. van der Sloot, Jasmin Coulombe‐Huntington, Michael P. Rout, Nitin S. Baliga +8 more

Structural basis of substrate recognition by a polypeptide processing and secretion transporter

eLife(2020)10.7554/elife.51492

N/A

0DataRank · unranked

37 citations

Paul Dominic B. Olinares, Anthony Palillo, Michael L. Oldham, Brian T. Chait, Jue Chen +1 more

The Molecular Architecture of the Nuclear Basket

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.27.587068

N/A

0DataRank · unranked

5 citations

Neelesh Soni, Joshua Hutchings, Ignacia Echeverria, Farhaz Shaikh, Madeleine Duquette +13 more

Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.08.611915

N/A

0DataRank · unranked

1 citations

Noa E. Dahan, Wenzhu Zhang, Matthew J. Reynolds, Brian T. Chait, Tarun M. Kapoor +1 more

Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies

Structure(2025)10.1016/j.str.2025.01.019

N/A

0DataRank · unranked

16 citations

Peter C. Fridy, V.N. Malashkevich, Tanmoy Sanyal, Marc Brillantes, Mary Kay Thompson +7 more

Integrative structure and function of the yeast exocyst complex

Protein Science(2020)10.1002/pro.3863

N/A

0DataRank · unranked

52 citations

Michael Feyder, Ilan E. Chemmama, Fei Fang, Michael P. Rout, Brian T. Chait +4 more

Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2519643122

N/A

0DataRank · unranked

8 citations

A. Chakravarti, Zhiying Zhang, Josephine L. Ramirez, Alba Herrero del Valle, Paul Dominic B. Olinares +8 more

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex

Molecular Cell(2025)10.1016/j.molcel.2025.02.013

N/A

0DataRank · unranked

11 citations

Donna Garvey Brickner, Kara Zehr, Wenzhu Zhang, Christopher A. Caffalette, Gavin C. Moeller +8 more

Targeted detection of endogenous LINE-1 proteins and ORF2p interactions

Mobile DNA(2025)10.1186/s13100-024-00339-4

N/A

0DataRank · unranked

7 citations

Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie +11 more

DnaB and DciA: mechanisms of helicase loading and translocation on ssDNA

Nucleic Acids Research(2025)10.1093/nar/gkaf521

N/A

0DataRank · unranked

4 citations

Daniele Mazzoletti, Adele Peng, Paul Dominic B. Olinares, Castrese Morrone, Andrea Garavaglia +12 more

A Nature-Inspired Ion Trap for Parallel Manipulation of Ions on a Massive Scale

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.21.671534

N/A

0DataRank · unranked

0 citations

Brian T. Chait, Andrew N. Krutchinsky

Distinct quaternary states, intermediates, and autoinhibition during loading of the DnaB-replicative helicase by the phage λP helicase loader

Nucleic Acids Research(2025)10.1093/nar/gkaf1139

N/A

0DataRank · unranked

0 citations

Dhanjai Brown, Paul Dominic B. Olinares, Jillian Chase, Eta A. Isiorho, Brian T. Chait +2 more

Division of labor in trypanosome RNA processing and export through expanded Mex67 paralogs

Nucleic Acids Research(2025)10.1093/nar/gkaf1443

N/A

0DataRank · unranked

0 citations

Peter C. Fridy, Eva Hegedűsová, Trevor van Eeuwen, Milana E. Stein, Wenzhu Zhang +9 more

A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Nucleic Acids Research(2021)10.1093/nar/gkaa1262

N/A

0DataRank · unranked

44 citations

Xiaolu Zhao, Fengbiao Mao, Venkatesha Basrur, Beatrix Ueberheide, Brian T. Chait +6 more

Dissecting the Structural Dynamics of the Nuclear Pore Complex

Molecular Cell(2020)10.1016/j.molcel.2020.11.032

N/A

0DataRank · unranked

60 citations

Kelly R. Molloy, Sarah Keegan, Thurston Herricks, Dante Lepore, Mary Munson +7 more

Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

eLife(2021)10.7554/elife.65282

N/A

0DataRank · unranked

55 citations

Joseph E. Darling, Alan Merk, Jinfeng Shao, Geervani Daggupati, Prakash Srinivasan +7 more

Analysis of the mechanosensor channel functionality of TACAN

eLife(2021)10.7554/elife.71188

N/A

0DataRank · unranked

37 citations

Xiao Tao, George Vaisey, Paul Dominic B. Olinares, Hanan Alwaseem, Brian T. Chait +2 more