Jan H.J. Hoeijmakers

Also affiliated with Erasmus MC, Oncode Institute, Princess Máxima Center, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Erasmus MC Cancer Institute, Max Planck Institute for Biology of Ageing

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “ARDD 2020: from aging mechanisms to interventions”.

ARDD 2020: from aging mechanisms to interventions

Aging(2020)10.18632/aging.202454

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0.609DataRank · unranked

57 citations

Kotb Abdelmohsen, Pénélope A. Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak +61 more

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Nature Communications(2024)10.1038/s41467-024-50584-7

N/A

0.529DataRank · unranked

16 citations

Shun-Hsiao Lee, Katarzyna W. Kliza, Arjan F. Theil, Masaki Akita, Angela Helfricht +15 more

Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

Frontiers in Aging Neuroscience(2023)10.3389/fnagi.2022.1095801

N/A

0.373DataRank · unranked

11 citations

Lisanne J. van’t Sant, Renata M. C. Brandt, Sander Barnhoorn, Jan H.J. Hoeijmakers, Wilbert P. Vermeij +2 more

Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice

Journal of Cachexia Sarcopenia and Muscle(2024)10.1002/jcsm.13433

N/A

0.373DataRank · unranked

11 citations

Wei Yang, Luojiao Huang, Marlien Admiraal‐van Mever, Rawi Ramautar, Amy C. Harms +10 more

Gene expression changes in cerebellum induced by dietary restriction

Frontiers in Molecular Neuroscience(2023)10.3389/fnmol.2023.1185665

N/A

0.165DataRank · unranked

2 citations

María B. Birkisdóttir, Rutger A. Ozinga, Ákos Gyenis, Jan H.J. Hoeijmakers, Wilbert P. Vermeij +2 more

Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice

Frontiers in Immunology(2022)10.3389/fimmu.2022.800606

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0DataRank · unranked

24 citations

Carolina Quayle, Camila García, Wesley Luzetti Fotoran, Juliana F. R. dos Santos, Gijsbertus T. J. van der Horst +3 more

The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

Frontiers in Aging(2022)10.3389/fragi.2022.1005322

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0DataRank · unranked

13 citations

Ivar van Galen, Renata M. C. Brandt, Sander Barnhoorn, Nicole van Vliet, Claire van Dijk +12 more

Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity

Frontiers in Pediatrics(2022)10.3389/fped.2022.828615

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0DataRank · unranked

4 citations

Winnie M. C. van den Boogaard, Daphne S. J. Komninos, Emma J. Verwaaijen, Hanneke M. van Santen, Marc R. Liliën +5 more

The regulatory landscapes of human ovarian ageing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.18.492547

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0DataRank · unranked

11 citations

Xizhe Wang, Adam D. Hudgins, Amir Gamliel, Mingzhuo Pei, Seung-Soo Kim +8 more

The regulatory landscapes of human ovarian ageing

Research Square(2022)10.21203/rs.3.rs-1661835/v1

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0DataRank · unranked

0 citations

Chen Jin, Xizhe Wang, Adam D. Hudgins, Amir Gamliel, Mingzhuo Pei +8 more

Genome-wide RNA polymerase stalling shapes the transcriptome during aging

Nature Genetics(2023)10.1038/s41588-022-01279-6

N/A

0DataRank · unranked

139 citations

Jiang Chang, Joris Demmers, Serena T. Bruens, Sander Barnhoorn, Renata M. C. Brandt +6 more

DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice

Aging Cell(2023)10.1111/acel.13768

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0DataRank · unranked

34 citations

Maaike te Lintel Hekkert, Jiang Chang, Bibi S. van Thiel, Leonie Martens, Maxime M. Bos +26 more

Trichothiodystrophy‐associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation

EMBO Molecular Medicine(2023)10.15252/emmm.202317973

N/A

0DataRank · unranked

12 citations

Alex Pines, Tuğba Kalaycı, José María Heredia‐Genestar, Anja Raams, Marion Rietveld +15 more

Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice

European Thyroid Journal(2023)10.1530/etj-22-0231

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0DataRank · unranked

7 citations

Marcel E. Meima, Robin P. Peeters, Veerle Darras, Selmar Leeuwenburgh, Jan H.J. Hoeijmakers +3 more

DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II

Research Square(2023)10.21203/rs.3.rs-3385435/v1

N/A

0DataRank · unranked

3 citations

Diana A. Llerena Schiffmacher, Shun-Hsiao Lee, Katarzyna W. Kliza, Arjan F. Theil, Masaki Akita +15 more

Reduced frequency of clonal hematopoiesis in Parkinson’s disease patients

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.04.539397

N/A

0DataRank · unranked

2 citations

Daisy Sproviero, César Payán‐Gómez, Zhenqiu Huang, Jan H.J. Hoeijmakers, Alexander Y. Maslov +3 more

Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses

Nature Aging(2024)10.1038/s43587-024-00762-5

N/A

0DataRank · unranked

78 citations

Xizhe Wang, Jiping Yang, Seung-Soo Kim, Adam D. Hudgins, Amir Gamliel +13 more

Time is ticking faster for long genes in aging

Trends in Genetics(2024)10.1016/j.tig.2024.01.009

N/A

0DataRank · unranked

34 citations

Olga Ibáñez-Solé, Ander Izeta, Jan H.J. Hoeijmakers, Thomas Stoeger, Sourena Soheili‐Nezhad

Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice

Molecular Imaging and Biology(2024)10.1007/s11307-024-01902-4

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0DataRank · unranked

2 citations

Martine de Boer, Yanto Ridwan, Marion G. J. de Kleijnen, Nicole van Vliet, Janette van der Linden +10 more

Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.04.592535

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0DataRank · unranked

1 citations

Moonsook Lee, Xiaoxiao Hao, Joseph Ehlert, Zhongxuan Chi, Bo Jin +7 more

High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice

npj Metabolic Health and Disease(2025)10.1038/s44324-025-00064-3

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0DataRank · unranked

6 citations

María B. Birkisdóttir, Rutger A. Ozinga, Renata M. C. Brandt, Sander Barnhoorn, Sandra Imholz +10 more

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS ‐ STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA ‐Repair‐Deficient Ercc1 Δ /− Mice

Aging Cell(2025)10.1111/acel.70062

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0DataRank · unranked

3 citations

Janette van der Linden, José María Heredia‐Genestar, Renata M. C. Brandt, Sander Barnhoorn, Ingeborg Nieuwenhuizen‐Bakker +10 more

Divergent accumulation patterns of SNVs and INDELs reveal negative selection in noncancerous cells

The Innovation(2025)10.1016/j.xinn.2025.101008

N/A

0DataRank · unranked

1 citations

Moonsook Lee, Xiaoxiao Hao, Xiao Ma, Chuwei Xia, Yiwei Zhao +11 more

Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction

Clinical Science(2020)10.1042/cs20190124

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0DataRank · unranked

43 citations

Eliana Portilla-Fernández, Eloísa Rubio‐Beltrán, Janette J. van der Linden, René de Vries, Richard van Veghel +20 more

Preoperative short-term fasting in paediatric cancer care is safe, feasible and activates protective responses

EJC Paediatric Oncology(2025)10.1016/j.ejcped.2025.100309

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0DataRank · unranked

0 citations

Christiaan A. J. Oudmaijer, Rutger A. Ozinga, Kevin Smit, Jan N.M. IJzermans, Jan H.J. Hoeijmakers +4 more

Protein and calorie restriction may improve outcomes in living kidney donors and kidney transplant recipients

Aging(2020)10.18632/aging.103619

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0DataRank · unranked

29 citations

Ron W.F. de Bruin, Harry van Steeg, Piet Beekhof, Paul Wackers, Dennis A. Hesselink +4 more

Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy

Human Molecular Genetics(2021)10.1093/hmg/ddab123

N/A

0DataRank · unranked

49 citations

Arjan F. Theil, Anja Raams, Giuseppina Caligiuri, Sarah Giachetti, Silvia Bione +15 more

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01200-y

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0DataRank · unranked

20 citations

Joshua J. White, Jan H.J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma, Lisanne J. van’t Sant

Different responses to DNA damage determine ageing differences between organs

Aging Cell(2022)10.1111/acel.13562

N/A

0DataRank · unranked

29 citations

Joris Demmers, Wilbert P. Vermeij, Marjolein P. Baar, Serena T. Bruens, Aristea Magaraki +10 more