George M. Church

ORCID: 0000-0003-3535-2076

Also affiliated with Harvard University, Harvard University Press

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.5Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

Nature Communications(2021)10.1038/s41467-021-23576-0

Top 5%

4.1DataRank

Top 5%207 citations

Giulia I. Corsi, Christian Anthon, Kunli Qu, Xiaoguang Pan, Xue Liang +19 more

Papers

Driven by 55 papers — median percentile 85. Top paper: “Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning”.

Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

Nature Communications(2021)10.1038/s41467-021-23576-0

Top 5%

4.1DataRank

Top 5%207 citations

Giulia I. Corsi, Christian Anthon, Kunli Qu, Xiaoguang Pan, Xue Liang +19 more

The whale shark genome reveals how genomic and physiological properties scale with body size

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1922576117

Top 15%

1.3DataRank

Top 15%53 citations

Seung Gu Park, Victor Luria, Sungwon Jeon, Hak‐Min Kim, Yeonsu Jeon +15 more

Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight

Nature Microbiology(2024)10.1038/s41564-024-01635-8

N/A

1.2DataRank · unranked

74 citations

JangKeun Kim, Eliah Overbey, Krista Ryon, Jonathan Foox, Maria A. Sierra +32 more

Codon usage of highly expressed genes affects proteome-wide translation efficiency

Proceedings of the National Academy of Sciences(2018)10.1073/pnas.1719375115

N/A

0.852DataRank · unranked

291 citations

Marc J. Lajoie, Christopher J. Gregg, Gil Hornung, George M. Church, Yitzhak Pilpel +1 more

The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing

Nature Biotechnology(2020)10.1038/s41587-020-0655-4

N/A

0.700DataRank · unranked

105 citations

Anna C. Hooker, Ebrahim Afshinnekoo, Marc Salit, Jason M. Kelly, Jonathan V. Feldstein +15 more

Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses

Nucleic Acids Research(2021)10.1093/nar/gkab120

N/A

0.637DataRank · unranked

69 citations

Sukanya Punthambaker, Eswar Prasad R. Iyer, Thomas C. Ferrante, Daniel R. Goodwin, Daniel Fürth +20 more

Characterizing the portability of phage-encoded homologous recombination proteins

Nature Chemical Biology(2021)10.1038/s41589-020-00710-5

N/A

0.633DataRank · unranked

67 citations

Timothy M. Wannier, Felix Boel Pedersen, Isaac D. Lutz, Julie Zhang, Devon A. Stork +13 more

Gain-of-function RHOA mutations promote focal adhesion kinase activation and dependency in diffuse gastric cancer

UNC Libraries(2021)10.17615/1nrz-k190

N/A

0.416DataRank · unranked

15 citations

J. Zhou, Devon R Blake, S. Derks, M. Pierobon, Richard G. Hodge +19 more

Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer’s Disease and Autoimmune Diseases

Cells(2024)10.3390/cells13231978

N/A

0.362DataRank · unranked

8 citations

Emma Vanderleeden, Nathaniel Barton, Sambra D. Redick, Pepper Dawes, Liam F. Murray +13 more

Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1

mBio(2025)10.1128/mbio.01871-25

N/A

0.334DataRank · unranked

8 citations

Shu-Fan Chou, Priya Raja, Jaehoon Shim, Biswajit Das, Jean M. Pesola +9 more

Impaired neural stress resistance and loss of REST in bipolar disorder

Molecular Psychiatry(2023)10.1038/s41380-023-02313-7

N/A

0.330DataRank · unranked

8 citations

King‐Hwa Ling, Pei-Ling Yeo, Angeliki Spathopoulou, Derek Drake, Jaejoon Choi +10 more

The inherent challenges of classifying senescence—Response

Science(2020)10.1126/science.abb4073

N/A

0.311DataRank · unranked

5 citations

Barry L. Bentley, Claire E. Stewart, Graham Pawelec, Angelo Scuteri, Manlio Vinciguerra +20 more

Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation

Research Square(2023)10.21203/rs.3.rs-2493867/v1

N/A

0.172DataRank · unranked

2 citations

Braden Tierney, JangKeun Kim, Eliah Overbey, Krista Ryon, Jonathan Foox +32 more

EditABLE: A Simple Web Application for Designing Genome Editing Experiments

Research Square(2024)10.21203/rs.3.rs-4775705/v1

N/A

0.104DataRank · unranked

1 citations

David Wu, Najani Shanee Johnson, Vivek Charu, Jennefer N. Carter, Shuchi Anand +3 more

Geospatially-resolved public-health surveillance via wastewater sequencing

medRxiv(2023)10.1101/2023.05.31.23290781

N/A

0.104DataRank · unranked

1 citations

Jonathan Foox, Krista Ryon, Daniel Butler, Namita Damle, B. G. Young +30 more

A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules

Nature Cell Biology(2022)10.1038/s41556-022-01005-8

N/A

0DataRank · unranked

16 citations

Qingxuan Zhou, Kurt J. Cox, Benjamin K. Law, Miseon Lee, Praveen Kokkonda +17 more

Expanding Homogeneous Culture of Human Primordial Germ Cell–Like Cells Maintaining Germline Features Without Serum or Feeder Layers

Obstetrical & Gynecological Survey(2022)10.1097/01.ogx.0000827980.67713.d1

N/A

0DataRank · unranked

3 citations

Misato Kobayashi, Junko Odajima, Keiko Shioda, Young Sun Hwang, Kotaro Sasaki +11 more

Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.03.494617

N/A

0DataRank · unranked

8 citations

Li Li, Fan Zhang, Björn van Sambeek, Evan Appleton, Alex H. M. Ng +13 more

Massively Targeted Evaluation of Therapeutic CRISPR Off-Targets in Cells

Research Square(2022)10.21203/rs.3.rs-1427273/v1

N/A

0DataRank · unranked

3 citations

Kunli Qu, Hao Yuan, Xi Xiang, Christian Anthon, Liubov Pashkova +20 more

Reliable multiplex generation of pooled induced pluripotent stem cells for genetic testing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.10.500520

N/A

0DataRank · unranked

3 citations

Julia Reichert, Pepper Dawes, Qi Wang, Benjamin Readhead, George M. Church +3 more

Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.31.502046

N/A

0DataRank · unranked

2 citations

Alex Vaughan, Daniel Leible, Shahar Alon, Gilbert L. Henry, A. H. Cheng +13 more

oFlowSeq: A multiplexed quantitative approach to identify genes affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids

Research Square(2022)10.21203/rs.3.rs-1825493/v1

N/A

0DataRank · unranked

0 citations

Molly Smullen, Aria Fernandez-Fontaine, Yucheng Zhang, ChangHui Pak, Mohammed Uddin +4 more

Design and testing of a humanized porcine donor for xenotransplantation

Nature(2023)10.1038/s41586-023-06594-4

N/A

0DataRank · unranked

268 citations

Jacob V. Layer, Dávid Héja, Takayuki Hirose, Grace Lassiter, Daniel J. Firl +55 more

A swapped genetic code prevents viral infections and gene transfer

Nature(2023)10.1038/s41586-023-05824-z

N/A

0DataRank · unranked

96 citations

Svenja Vinke, Regan Flynn, Siân V. Owen, Eleanor A. Rand, Bogdan Budnik +11 more

Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability

Materials Today Bio(2023)10.1016/j.mtbio.2023.100560

N/A

0DataRank · unranked

95 citations

Jing Zhang, Jenny M. Tam, George M. Church, Ahmad S. Khalil, Daniel Segrè +2 more

PAM-flexible genome editing with an engineered chimeric Cas9

Nature Communications(2023)10.1038/s41467-023-41829-y

N/A

0DataRank · unranked

57 citations

Sabrina Koseki, Rachel A. Silverstein, Nadia Amrani, Christina Peng, Christian Kramme +17 more

Core commitments for field trials of gene drive organisms

Science(2020)10.1126/science.abd1908

N/A

0DataRank · unranked

111 citations

Luke Alphey, George J. Annas, Cinnamon S. Bloss, Karl J. Campbell, Jackson Champer +39 more

oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids

Human Genetics(2023)10.1007/s00439-023-02534-4

N/A

0DataRank · unranked

10 citations

Liam F. Murray, Meagan N. Olson, Nathaniel Barton, Molly Smullen, Madhusoodhanan Suresh +9 more

Reliable multiplex generation of pooled induced pluripotent stem cells

Cell Reports Methods(2023)10.1016/j.crmeth.2023.100570

N/A

0DataRank · unranked

5 citations

Meagan N. Olson, Julia Reichert, Pepper Dawes, Liam F. Murray, Christina E. Baer +6 more

Engineering Ca 2+ -Dependent DNA Polymerase Activity

ACS Synthetic Biology(2023)10.1021/acssynbio.3c00302

N/A

0DataRank · unranked

1 citations

Alexandra M. de Paz, Namita Bhan, Thaddeus R. Cybulski, George M. Church, Keith E. J. Tyo +1 more

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.13.544841

N/A

0DataRank · unranked

4 citations

Douglas G. Paton, George M. Church, Kevin M. Esvelt, W. Robert Shaw, Flaminia Catteruccia +1 more

Cryptography in the DNA of living cells enabled by multi-site base editing

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.15.567131

N/A

0DataRank · unranked

1 citations

Simon Zhang, Karen M. Song, Sharon Qian, Fei Chen, George M. Church +1 more

Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer

Cancer Cell(2024)10.1016/j.ccell.2024.08.002

N/A

0DataRank · unranked

66 citations

Adrien Grimont, Jiwoon Park, Yinuo Meng, Whitney J. Sisso, Kenneth Seier +26 more

Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions

Nucleic Acids Research(2024)10.1093/nar/gkae592

N/A

0DataRank · unranked

33 citations

Xiaoyu Liu, Yitian Zeng, Sinem K. Saka, Wenxin Xie, Isabel Goldaracena +4 more

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males

Scientific Reports(2024)10.1038/s41598-024-54498-8

N/A

0DataRank · unranked

23 citations

Eryney Marrogi, Jamie Kauffman, Douglas G. Paton, Kathleen A. Westervelt, George M. Church +4 more

Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.21.585957

N/A

0DataRank · unranked

4 citations

Pepper Dawes, Liam F. Murray, Nathaniel Barton, Jonathan Sundstrom, Adrian R. Orszulak +20 more

Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Transcripts Associated with Alzheimer’s Disease and Autoimmune Diseases

Preprints.org(2024)10.20944/preprints202407.1267.v1

N/A

0DataRank · unranked

2 citations

Emma Vanderleeden, Nathaniel Barton, Sambra D. Redick, Pepper Dawes, Liam F. Murray +13 more

DNA-PAINT Imaging with Hydrogel Imprinting and Clearing

ACS Sensors(2025)10.1021/acssensors.5c00616

N/A

0DataRank · unranked

4 citations

Lorenzo Magni, George M. Church, Johannes Stein

Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2504578122

N/A

0DataRank · unranked

2 citations

Maria Ericsson, Michel Nofal, Lorenzo Magni, Sarah Aufmkolk, Ryan B. McMillan +11 more

Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae

Scientific Reports(2025)10.1038/s41598-025-18484-y

N/A

0DataRank · unranked

0 citations

Eryney Marrogi, Sean Scott, Enzo Mameli, Daniel G. Abernathy, Omar S. Akbari +4 more

Mitigating age-related somatic mutation burden

Trends in Molecular Medicine(2023)10.1016/j.molmed.2023.04.002

N/A

0DataRank · unranked

24 citations

Björn Schumacher, Abdulkadir Abakir, Michael Antonov, Chris Bradley, Alex Cagan +9 more

Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology

ACS Nano(2020)10.1021/acsnano.0c04753

N/A

0DataRank · unranked

100 citations

Marina A. Dobrovolskaia, George M. Church, Mark Bathe, Kirill A. Afonin

A machine learning toolkit for genetic engineering attribution to facilitate biosecurity

Nature Communications(2020)10.1038/s41467-020-19612-0

N/A

0DataRank · unranked

33 citations

Miles Turpin, Andrew Bo Liu, Taylor Kulp-McDowall, Jacob Swett, Rey Edison +4 more

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.02.973289

N/A

0DataRank · unranked

10 citations

Ruei‐Zeng Lin, Xuechong Hong, Alex H. M. Ng, Chin Nien Lee, Joseph Neumeyer +7 more

An orthogonal differentiation platform for genomically programming stem cells, organoids, and bioprinted tissues

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.11.198671

N/A

0DataRank · unranked

10 citations

Jeremy Huang, Aric Lu, Alex H. M. Ng, Tomoya Duenki, Lucy Nam +4 more

Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.20.103614

N/A

0DataRank · unranked

4 citations

Kunli Qu, Xue Liang, Xiaoguang Pan, Jun Wang, Peng Han +24 more

Characterizing the portability of RecT-mediated oligonucleotide recombination

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.14.041095

N/A

0DataRank · unranked

3 citations

Timothy M. Wannier, Felix Boel Pedersen, Isaac D. Lutz, Julie Zhang, Devon A. Stork +13 more

Data integration of bulk and single-cell transcriptomics from cerebral organoids and post-mortem brains to identify cell types and cell type specific driver genes in autism

Research Square(2020)10.21203/rs.3.rs-113869/v1

Top 100%

0DataRank

Top 100%0 citations

Yingleong Chan, Mannix J. Burns, Xiaoge Guo, Serkan Erdin, Derek J.C. Tai +13 more

Lineage barcoding in mice with homing CRISPR

Nature Protocols(2021)10.1038/s41596-020-00485-y

N/A

0DataRank · unranked

34 citations

Kian Kalhor, Andyna Vernet, Amanda Graveline, George M. Church, Prashant Mali +2 more

Designing efficient genetic code expansion in Bacillus subtilis to gain biological insights

Nature Communications(2021)10.1038/s41467-021-25691-4

N/A

0DataRank · unranked

28 citations

Georgia R. Squyres, Erkin Kuru, Katarzyna A. Gromek, Jonathan Rittichier, Aditya Jog +5 more

Recording Temporal Signals with Minutes Resolution Using Enzymatic DNA Synthesis

Journal of the American Chemical Society(2021)10.1021/jacs.1c07331

N/A

0DataRank · unranked

26 citations

Alec Callisto, Jonathan Strutz, Joshua I. Glaser, Reza Kalhor, Edward S. Boyden +4 more

Recording Temporal Signals with Minutes Resolution Using Enzymatic DNA Synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.14.452380

N/A

0DataRank · unranked

1 citations

Alec Callisto, Jonathan Strutz, Joshua I. Glaser, Reza Kalhor, Edward S. Boyden +4 more

One-Seq: A Highly Scalable Sequencing-Based Diagnostic for SARS-CoV-2 and Other Single-Stranded Viruses

medRxiv(2021)10.1101/2021.04.12.21253357

N/A

0DataRank · unranked

0 citations

Wenzhe Ma, Hong Mo Kang, Matthew Sonnett, George M. Church, Marc W. Kirschner +1 more

Massively targeted evaluation of therapeutic CRISPR off-targets in cells

Nature Communications(2022)10.1038/s41467-022-31543-6

N/A

0DataRank · unranked

38 citations

Kunli Qu, Hao Yuan, Xi Xiang, Christian Anthon, Liubov Pashkova +20 more

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

Nature Communications(2022)10.1038/s41467-022-30968-3

N/A

0DataRank · unranked

27 citations

Yingleong Chan, Pepper Dawes, Xiaoge Guo, Serkan Erdin, Derek J.C. Tai +15 more

George M. Church

Indexed papers

Top data-sharing exemplar

Papers