Cassandra N. Spracklen

Also affiliated with University of Massachusetts Amherst

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.899Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multi-omics characterization of type 2 diabetes associated genetic variation

medRxiv(2024)10.1101/2024.07.15.24310282

Top 41%

0.470DataRank

Top 41%12 citations

Kimberly Lorenz, Xianyong Yin, Ozvan Bocher, Alicia Huerta‐Chagoya, Ana Luiza Arruda +27 more

Papers

Driven by 39 papers — median percentile 58. Top paper: “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations”.

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Cell(2020)10.1016/j.cell.2020.06.045

N/A

8.3DataRank · unranked

739 citations

Laura M. Raffield, Abdou Mousas, Saori Sakaue, Jennifer E. Huffman, Arden Moscati +95 more

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Nature Genetics(2022)10.1038/s41588-021-00997-7

N/A

7.2DataRank · unranked

363 citations

Deepti Jain, Zhili Zheng, TOPMed Anthropometry Working Group, Stella Aslibekyan, Diane M. Becker +95 more

Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

Communications Biology(2022)10.1038/s42003-022-03248-5

N/A

1.5DataRank · unranked

62 citations

Weihua Zhang, Hong Kiat Ng, Katharina T. Schmid, Amel Lamri, Tong Lin +42 more

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

Diabetes(2020)10.2337/db20-0070

N/A

1.5DataRank · unranked

57 citations

Yiying Zhang, Cassandra N. Spracklen, Tugce Karaderi, Lam Opal Huang, Jonathan P. Bradfield +95 more

A saturated map of common genetic variants associated with human height

Nature(2022)10.1038/s41586-022-05275-y

N/A

1.0DataRank · unranked

911 citations

Sailaja Vedantam, Eirini Marouli, Julia Sidorenko, Eric Bartell, Saori Sakaue +95 more

The trans-ancestral genomic architecture of glycemic traits

Nature Genetics(2021)10.1038/s41588-021-00852-9

N/A

1.0DataRank · unranked

907 citations

Cassandra N. Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J. Corbin, Jian’an Luan +95 more

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Nature Genetics(2022)10.1038/s41588-022-01058-3

N/A

0.994DataRank · unranked

754 citations

Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng, Lauren E. Petty, Hidetoshi Kitajima +95 more

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Cell(2020)10.1016/j.cell.2020.08.008

N/A

0.988DataRank · unranked

722 citations

Erik L. Bao, Parsa Akbari, Caleb A. Lareau, Abdou Mousas, Tao Jiang +95 more

Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH

Diabetologia(2023)10.1007/s00125-023-05922-7

N/A

0.676DataRank · unranked

16 citations

Laura Brenner, Varinderpal Kaur, Katherine Figueroa, Philip Schroeder, Alicia Huerta‐Chagoya +95 more

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Nature Medicine(2025)10.1038/s41591-025-03827-z

N/A

0.665DataRank · unranked

34 citations

Kaitlin H Wade, Qin Hui, Joshua Arias, Xianyong Yin, Malene R. Christiansen +95 more

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Communications Biology(2022)10.1038/s42003-022-03448-z

N/A

0.553DataRank · unranked

39 citations

Humaira Rasheed, Alexander Teumer, Mathias Gorski, Bryce Rowan, Kira J. Stanzick +94 more

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

PLoS Genetics(2020)10.1371/journal.pgen.1009019

N/A

0.470DataRank · unranked

22 citations

Apoorva K. Iyengar, Swarooparani Vadlamudi, Chelsea K. Raulerson, Anne Jackson, Sarah M. Brotman +20 more

Multi-omics characterization of type 2 diabetes associated genetic variation

medRxiv(2024)10.1101/2024.07.15.24310282

Top 41%

0.470DataRank

Top 41%12 citations

Kimberly Lorenz, Xianyong Yin, Ozvan Bocher, Alicia Huerta‐Chagoya, Ana Luiza Arruda +27 more

Additive Value of Polygenic Risk Score to Family History for Type 2 Diabetes Prediction: Results From the All of Us Research Database

Diabetes Care(2025)10.2337/dc24-1537

Top 43%

0.429DataRank

Top 43%4 citations

Laura M. Raffield, Katherine Kolor, Alain K. Koyama, Ramal Moonesinghe, Meda E. Pavkov +3 more

Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.27.630525

N/A

0.312DataRank · unranked

7 citations

Byungchang Jin, Olivia Sun, Edwin De Jesus Lopez Gonzalez, Min-Hsuan Chen, Xiwei Wu +7 more

Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in citrin deficiency

Nature Metabolism(2025)10.1038/s42255-025-01399-3

N/A

0.292DataRank · unranked

6 citations

Byungchang Jin, Olivia Sun, Edwin D. J. Lopez Gonzalez, Min-Hsuan Chen, Xiwei Wu +7 more

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities

Nature Communications(2025)10.1038/s41467-025-64927-5

N/A

0.292DataRank · unranked

6 citations

Ozvan Bocher, Henry J. Taylor, Davis Cammann, Satoshi Yoshiji, Xianyong Yin +14 more

Associations of maternal preterm birth with subsequent risk for type 2 diabetes in women from the women’s health initiative

Journal of Developmental Origins of Health and Disease(2023)10.1017/s2040174423000089

N/A

0.292DataRank · unranked

6 citations

Brian Monahan, Erin S. LeBlanc, Simin Liu, Rami Nassir, Nazmus Saquib +9 more

Preterm birth, birthweight, and subsequent risk for depression

Journal of Developmental Origins of Health and Disease(2023)10.1017/s2040174423000296

N/A

0.241DataRank · unranked

4 citations

Aaron Holman-Vittone, Christian Daniele, Rachel Wacks, Autumn Gagnon, Amy L. D’Agata +6 more

Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease

Genome Medicine(2025)10.1186/s13073-025-01522-9

N/A

0.241DataRank · unranked

4 citations

Heather M. Highland, Roelof A. J. Smit, Micah R. Hysong, Victoria L. Buchanan, Kristin L. Young +27 more

Association of maternal birth weight and maternal preterm birth with subsequent risk for adverse reproductive outcomes: The Women's Health Initiative

Early Human Development(2023)10.1016/j.earlhumdev.2023.105839

N/A

0.229DataRank · unranked

3 citations

Leslie V. Farland, Ki Park, Peter F. Schnatz, Aladdin H. Shadyab, Marcia L. Stefanick +4 more

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries

The Lancet Diabetes & Endocrinology(2026)10.1016/s2213-8587(25)00405-x

N/A

0.208DataRank · unranked

3 citations

Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E Petty +255 more

Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissues

medRxiv(2025)10.1101/2025.05.05.25326880

N/A

0.104DataRank · unranked

1 citations

Ana Luiza Arruda, Satoshi Yoshiji, Chi Zhao, Chen‐Yang Su, Xianyong Yin +19 more

Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs

Frontiers in Genetics(2020)10.3389/fgene.2020.00008

N/A

0DataRank · unranked

17 citations

Dong Li, Taylor B. Poston, Toni Darville, Cassandra N. Spracklen, Di Wu +5 more

Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity

(2020)10.2337/figshare.12933737.v1

N/A

0DataRank · unranked

0 citations

Hanieh Yaghootkar, Yiying Zhang, Cassandra N. Spracklen, Tugce Karaderi, Lam Opal Huang +95 more

Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia

UNC Libraries(2020)10.17615/908a-6231

N/A

0DataRank · unranked

0 citations

Audrey F. Saftlas, Patrick Breheny, Brendan J. Keating, Andrew Bjonnes, Cassandra N. Spracklen +7 more

Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights

Cell Metabolism(2024)10.1016/j.cmet.2024.09.006

N/A

0DataRank · unranked

24 citations

Romy Kursawe, Vijay Selvam, Redwan M. Bhuiyan, Asa Thibodeau, Chi Zhao +4 more

Associations between birthweight and preterm birth and the ages at menarche and menopause

BMC Women s Health(2024)10.1186/s12905-024-03384-6

N/A

0DataRank · unranked

2 citations

Rachel Wacks, Leslie V. Farland, JoAnn E. Manson, Lihong Qi, Aladdin H. Shadyab +3 more

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

UNC Libraries(2021)10.17615/4xxe-xj37

N/A

0DataRank · unranked

0 citations

Samantha Brotman, F.S. Collins, N. Narisu, A.K. Iyengar, A.T. Crain +20 more

Multi-SNP mediation intersection-union test

UNC Libraries(2021)10.17615/vtwp-4751

N/A

0DataRank · unranked

0 citations

Xuwei Zheng, Cassandra N. Spracklen, Karen L. Mohlke, Jeremiah Fine, Y. Li +1 more

Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs

UNC Libraries(2021)10.17615/awe1-qk20

N/A

0DataRank · unranked

1 citations

Quanpeng Li, Yanwei Li, Daipeng Wu, T.B. Poston, Karen L. Mohlke +5 more

Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women

Journal of Developmental Origins of Health and Disease(2021)10.1017/s204017442100057x

N/A

0DataRank · unranked

10 citations

Leslie V. Farland, Aladdin H. Shadyab, Susan E. Hankinson, JoAnn E. Manson, Cassandra N. Spracklen +1 more

Low Birth Weight and Risk of Later-Life Physical Disability in Women

UNC Libraries(2020)10.17615/kckq-y236

N/A

0DataRank · unranked

0 citations

Kelli K. Ryckman, Jennifer G. Robinson, Robert B. Wallace, Marcia L. Stefanick, Gloria E. Sarto +2 more

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

UNC Libraries(2020)10.17615/4t9n-sj07

N/A

0DataRank · unranked

0 citations

Yonghong Zhang, Yun Kyoung Kim, Wen‐Harn Pan, Woon‐Puay Koh, E. Shyong Tai +95 more

Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study

UNC Libraries(2020)10.17615/b58m-hz03

N/A

0DataRank · unranked

0 citations

Audrey F. Saftlas, Kelli K. Ryckman, Elizabeth W. Triche, Cassandra N. Spracklen

Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven β-cell gene expression defects

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.17.633590

N/A

0DataRank · unranked

14 citations

Efthymios Motakis, Siddhi Nargund, Romy Kursawe, Vijay Selvam, Redwan M. Bhuiyan +6 more

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities

medRxiv(2025)10.1101/2025.05.05.25326966

N/A

0DataRank · unranked

0 citations

Ozvan Bocher, Henry J. Taylor, Davis Cammann, Satoshi Yoshiji, Xianyong Yin +13 more

Validation of birth certificate and maternal recall of events in labor and delivery with medical records in the Iowa health in pregnancy study

BMC Pregnancy and Childbirth(2022)10.1186/s12884-022-04581-7

N/A

0DataRank · unranked

23 citations

Jenna Hillyer, Audrey F. Saftlas, Cassandra N. Spracklen, Christina Ziogas

A retrospective study of administration of vaccination for hepatitis B among newborn infants prior to hospital discharge at a midwestern tertiary care center

UNC Libraries(2020)10.17615/hth9-2649

N/A

0DataRank · unranked

0 citations

Cassandra N. Spracklen, Helen I. Myers, Jeffrey C. Murray, Kelli K. Ryckman

Cassandra N. Spracklen

Indexed papers

Top data-sharing exemplar

Papers