🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

David L. Spector

Brigham and Women's Hospital

ORCID: 0000-0003-3614-4965

Also affiliated with Cold Spring Harbor Laboratory, Stony Brook University

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile
2.5Author DataRank

Indexed papers

4in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Cancer Research(2022)10.1158/0008-5472.can-21-2807
Top 10%
2.1DataRank
Top 10%91 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

Papers

Driven by 20 papers — median percentile 27. Top paper: “Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics”.

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Cancer Research(2022)10.1158/0008-5472.can-21-2807
Top 10%
2.1DataRank
Top 10%91 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing

Genome Research(2020)10.1101/gr.260497.119
N/A
0.706DataRank · unranked
110 citations

Sara Goodwin, Rachel M. Sherman, Fritz J. Sedlazeck, Gayatri Arun, Sonam Bhatia +10 more

MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer

Cancer Discovery(2024)10.1158/2159-8290.cd-23-1529
N/A
0.500DataRank · unranked
27 citations

Damianos Skopelitis, Claudia Tonelli, Toyoki Yoshimoto, Aktan Alpsoy, Maria C. Panepinto +14 more

Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.09.455691
Top 46%
0.395DataRank
Top 46%8 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.04.614143
N/A
0.181DataRank · unranked
2 citations

Robert W. Sprung, Denis O. Okumu, José F. Olivares-Quintero, Chinmaya U. Joisa, Xin Chen +21 more

Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data

Journal of Computational Biology(2022)10.1089/cmb.2022.0357
N/A
0DataRank · unranked
9 citations

Robert Lanfear, David L. Spector, Sarah D. Diermeier, Alex Gavryushkin, Jiří C. Moravec

Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA sequencing datasets

Stem Cell Reports(2023)10.1016/j.stemcr.2023.10.004
N/A
0DataRank · unranked
8 citations

Raditya Utama, Payal Naik, Alexander Dobin, David L. Spector, Rasmani Hazra

Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.20.524887
N/A
0DataRank · unranked
1 citations

Raditya Utama, Payal Naik, Alexander Dobin, David L. Spector, Rasmani Hazra

Data from Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

(2023)10.1158/0008-5472.c.6513885.v1
Top 100%
0DataRank
Top 100%0 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.28.564411
N/A
0DataRank · unranked
0 citations

Payal Naik, Tse-Luen Wee, David L. Spector, Gayan I. Balasooriya

Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment

Cancer Cell(2024)10.1016/j.ccell.2024.01.013
N/A
0DataRank · unranked
261 citations

Yuan Gao, David Ng, Evdokia Michalopoulou, Shanu George, José M. Adrover +15 more

The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Nature Metabolism(2024)10.1038/s42255-024-01104-w
N/A
0DataRank · unranked
25 citations

Olivia T. Stamatatos, Qingting Hu, Jed Ruiter Swain, Suzanne Russo, Ava Sann +6 more

Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma

Nature Genetics(2024)10.1038/s41588-024-01790-y
N/A
0DataRank · unranked
15 citations

Patrick J. Cunniff, Allison C. Schier, Damianos Skopelitis, Marygrace C. Trousdell, Philip Moresco +15 more

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

UNC Libraries(2024)10.17615/m6mq-tz16
Top 100%
0DataRank
Top 100%0 citations

W. Richard McCombie, Jonathan Preall, G. Arun, Melissa Kramer, Karen Kostroff +13 more

MALAT1 Long Non-Coding RNA: Functional Implications

Non-Coding RNA(2020)10.3390/ncrna6020022
N/A
0DataRank · unranked
278 citations

Disha Aggarwal, David L. Spector, Gayatri Arun

Longitudinal tracking of MALAT1 level over a breast cancer patient’s course of treatment and disease progression

Molecular Therapy Oncology(2025)10.1016/j.omton.2025.201070
N/A
0DataRank · unranked
0 citations

Tse-Luen Wee, Shuchismita R. Satpathy, Suzanne Russo, David L. Spector, Disha Aggarwal

Activating a collaborative innate-adaptive immune response to control metastasis

Cancer Cell(2021)10.1016/j.ccell.2021.08.005
N/A
0DataRank · unranked
281 citations

Tim Kees, Ana S. Almeida, Bodu Liu, Xue‐Yan He, David Ng +7 more

Platr4 is an ESC-specific lncRNA that exhibits its function downstream on meso/endoderm lineage commitment

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.20.473435
N/A
0DataRank · unranked
1 citations

Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M. Shen +4 more

Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment

Developmental Cell(2022)10.1016/j.devcel.2022.10.002
N/A
0DataRank · unranked
17 citations

Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M. Shen +4 more

Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage

Nature Communications(2022)10.1038/s41467-022-33722-x
N/A
0DataRank · unranked
11 citations

David L. Spector, Gayan I. Balasooriya