Leena Haataja

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “Integration of ER protein quality control mechanisms defines β cell function and ER architecture”.

Integration of ER protein quality control mechanisms defines β cell function and ER architecture

Journal of Clinical Investigation(2022)10.1172/jci163584

N/A

0.590DataRank · unranked

50 citations

Mauricio Torres, Jason Zhang, You Lu, Leena Haataja, Rachel B. Reinert +8 more

Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size

JCI Insight(2021)10.1172/jci.insight.141553

N/A

0.571DataRank · unranked

44 citations

Yurong Xin, Qian Du, Daniela Georgieva, Giacomo Diedenhofen, Leena Haataja +15 more

“Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011389

N/A

0.494DataRank · unranked

15 citations

Ming Liu, Balamurugan Dhayalan, Yen‐Shan Chen, Nicholas A. Smith, Leili Rahimi +11 more

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

Diabetes(2021)10.2337/db21-0422

N/A

0.464DataRank · unranked

13 citations

Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John W. Kappler +3 more

A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data

EMBO Molecular Medicine(2026)10.1038/s44321-025-00362-9

N/A

0.104DataRank · unranked

1 citations

Marianne Becker, Ulrike Schierloh, Flávia Natividade da Silva, Leena Haataja, Ying Cai +27 more

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

Diabetes(2020)10.2337/db19-1106

N/A

0DataRank · unranked

31 citations

Yi Xiong, Xin Li, Leena Haataja, Wei Chen, Saiful A. Mir +14 more

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.25.007286

N/A

0DataRank · unranked

0 citations

Elizabeth Haythorne, Alejandra Tomás, Leena Haataja, Andreas Müller, Peter Arvan +26 more

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

Journal of Clinical Investigation(2021)10.1172/jci142240

N/A

0DataRank · unranked

68 citations

Yumeng Huang, Xiaoxi Xu, Xin Li, Maroof Alam, Anoop Arunagiri +9 more

PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones

Nature Communications(2021)10.1038/s41467-021-26225-8

N/A

0DataRank · unranked

51 citations

Jeffrey Knupp, Anoop Arunagiri, Leena Haataja, Peter Arvan, Billy Tsai +1 more

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

Molecular Metabolism(2020)10.1016/j.molmet.2020.101015

N/A

0DataRank · unranked

32 citations

Elizabeth Haythorne, Alejandra Tomás, Leena Haataja, Andreas Müller, Peter Arvan +26 more

Distinct states of proinsulin misfolding in MIDY

Cellular and Molecular Life Sciences(2021)10.1007/s00018-021-03871-1

N/A

0DataRank · unranked

34 citations

Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan +4 more

Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations

Molecular and Cellular Endocrinology(2020)10.1016/j.mce.2020.111025

N/A

0DataRank · unranked

18 citations

Cécile Saint‐Martin, Jialu Xu, Li Ding, Ruodan Wang, Wenli Feng +9 more

The ER transmembrane protein PGRMC1 recruits misfolded proteins for reticulophagic clearance

Autophagy(2021)10.1080/15548627.2021.1997062

N/A

0DataRank · unranked

8 citations

Yu-Jie Chen, Anoop Arunagiri, Leena Haataja, Peter Arvan, Billy Tsai +1 more

Distinct states of proinsulin misfolding in MIDY

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.10.442447

N/A

0DataRank · unranked

0 citations

Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan +4 more

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.01.446633

N/A

0DataRank · unranked

0 citations

Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John W. Kappler +3 more

Evolution of insulin at the edge of foldability and its medical implications

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2010908117

N/A

0DataRank · unranked

39 citations

Ming Liu, Yanwu Yang, Balamurugan Dhayalan, Nalinda P. Wickramasinghe, Yen‐Shan Chen +9 more

Proteasomal degradation of WT proinsulin in pancreatic beta cells

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102406

N/A

0DataRank · unranked

7 citations

Anoop Arunagiri, Leena Haataja, Maroof Alam, Shuhui Ji, Ling Qi +4 more

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.02.502357

N/A

0DataRank · unranked

4 citations

Emily M. Walker, Nathan Lawlor, Anne Lietzke, Vaibhav Sidarala, Jie Zhu +24 more

Nutrient-dependent regulation of β-cell proinsulin content

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104836

N/A

0DataRank · unranked

6 citations

Anoop Arunagiri, Maroof Alam, Leena Haataja, Charles R. Evans, Ivy Yan Zhao +8 more

Permanent Neonatal diabetes-causing Insulin mutations have dominant negative effects on beta cell identity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.01.555839

N/A

0DataRank · unranked

1 citations

Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola +7 more

Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity

Molecular Metabolism(2024)10.1016/j.molmet.2024.101879

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0DataRank · unranked

14 citations

Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola +7 more

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

Science(2025)10.1126/science.adf2034

N/A

0DataRank · unranked

61 citations

Gemma L. Pearson, Nathan Lawlor, Ava M. Stendahl, Anne Lietzke, Vaibhav Sidarala +25 more

Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis

Journal of Clinical Investigation(2025)10.1172/jci187341

N/A

0DataRank · unranked

0 citations

Leena Haataja, Maroof Alam, Noah Gleason, Emma Mastroianni, Chen Cheng +10 more