George‐Lucian Moldovan

Also affiliated with Penn State Milton S. Hershey Medical Center

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 31 papers. Top paper: “Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR”.

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR

Nucleic Acids Research(2020)10.1093/nar/gkaa508

N/A

1.1DataRank · unranked

30 citations

Emily M. Schleicher, Kristen E. Clements, Claudia M. Nicolae, George‐Lucian Moldovan, Ashna Dhoonmoon

Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly

Nature Communications(2020)10.1038/s41467-020-16096-w

N/A

0.740DataRank · unranked

138 citations

Wendy Leung, Claudia M. Nicolae, Kristen E. Clements, Binghui Shen, Anja‐Katrin Bielinsky +2 more

The emerging determinants of replication fork stability

Nucleic Acids Research(2021)10.1093/nar/gkab344

N/A

0.644DataRank · unranked

72 citations

George‐Lucian Moldovan, Tanay Thakar

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors

PLoS Genetics(2020)10.1371/journal.pgen.1009176

N/A

0.505DataRank · unranked

28 citations

Ashna Dhoonmoon, Lindsey M. Jackson, Kristen E. Clements, Coryn L. Stump, Claudia M. Nicolae +2 more

FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links

Nucleic Acids Research(2020)10.1093/nar/gkaa660

N/A

0.360DataRank · unranked

10 citations

Joshua A. Sommers, Arindam Datta, Sumeet U. Nayak, Marina A. Bellani, Olivia Yang +7 more

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival

Oncotarget(2022)10.18632/oncotarget.28277

N/A

0.292DataRank · unranked

6 citations

Emily M. Schleicher, Lindsey M. Jackson, Ashna Dhoonmoon, George‐Lucian Moldovan, Claudia M. Nicolae +1 more

Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells

Nucleic Acids Research(2021)10.1093/nar/gkab1184

N/A

0DataRank · unranked

26 citations

Ashna Dhoonmoon, Anastasia Hale, Kady A. Dennis, Emily M. Schleicher, Claudia M. Nicolae +2 more

CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery

FEBS Journal(2021)10.1111/febs.16217

N/A

0DataRank · unranked

12 citations

George‐Lucian Moldovan, Emily M. Schleicher

Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment

NAR Cancer(2022)10.1093/narcan/zcac042

N/A

0DataRank · unranked

62 citations

George‐Lucian Moldovan, Lindsey M. Jackson

The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1

Nature Communications(2022)10.1038/s41467-022-32756-5

N/A

0DataRank · unranked

47 citations

Claudia M. Nicolae, George‐Lucian Moldovan, Ashna Dhoonmoon

Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling

Nature Communications(2022)10.1038/s41467-022-33028-y

N/A

0DataRank · unranked

34 citations

Ashna Dhoonmoon, Joshua Straka, Emily M. Schleicher, Claudia M. Nicolae, George‐Lucian Moldovan +1 more

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

Journal of Clinical Investigation(2022)10.1172/jci147301

N/A

0DataRank · unranked

42 citations

Satpal S. Jhujh, Srijita Dhar, Joshua A. Sommers, Arindam Datta, Gabriel M. C. Longo +19 more

The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1

Scientific Reports(2022)10.1038/s41598-022-10385-8

N/A

0DataRank · unranked

17 citations

Fernanda Festa, Suming Huang, George‐Lucian Moldovan, Claudia M. Nicolae, Ashna Dhoonmoon +7 more

The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells

Oncogenesis(2022)10.1038/s41389-022-00410-w

N/A

0DataRank · unranked

16 citations

Ashna Dhoonmoon, Lindsey M. Jackson, Jude B. Khatib, Claudia M. Nicolae, George‐Lucian Moldovan +1 more

Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases

Nature Communications(2023)10.1038/s41467-023-42011-0

N/A

0DataRank · unranked

49 citations

Ashna Dhoonmoon, Joshua Straka, Claudia M. Nicolae, George‐Lucian Moldovan, Anastasia Hale

Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168275

N/A

0DataRank · unranked

25 citations

Claudia M. Nicolae, George‐Lucian Moldovan, Jude B. Khatib

FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination

Cell Reports(2023)10.1016/j.celrep.2023.113523

N/A

0DataRank · unranked

18 citations

Ryan M. Baxley, Emma L. Traband, Ya‐Chu Chang, Colette B. Rogers, Liangjun Wang +11 more

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

Cell Reports(2023)10.1016/j.celrep.2023.112296

N/A

0DataRank · unranked

8 citations

Andrew A. Kelso, Adak Karamafrooz, Yi‐Hsuan Chen, Wei‐Kai Chen, Chun‐Ting Cheng +10 more

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.526362

N/A

0DataRank · unranked

0 citations

Andrew A. Kelso, Adak Karamafrooz, Yi‐Hsuan Chen, Wei‐Kai Chen, Chun‐Ting Cheng +9 more

USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress

Nucleic Acids Research(2024)10.1093/nar/gkad1237

N/A

0DataRank · unranked

28 citations

Lindsey M Pale, Claudia M. Nicolae, George‐Lucian Moldovan, Alexandra Nusawardhana

PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis

Nature Communications(2024)10.1038/s41467-024-50429-3

N/A

0DataRank · unranked

22 citations

Ashna Dhoonmoon, George‐Lucian Moldovan, Claudia M. Nicolae, Jude B. Khatib

Novel insights into the role of bisphenol A (BPA) in genomic instability

NAR Cancer(2024)10.1093/narcan/zcae038

N/A

0DataRank · unranked

10 citations

George‐Lucian Moldovan, Anastasia Hale

CAF-1 promotes efficient PrimPol recruitment to nascent DNA for single-stranded DNA gap formation

Nucleic Acids Research(2024)10.1093/nar/gkae1068

N/A

0DataRank · unranked

3 citations

Jude B. Khatib, Lindsey M Pale, Claudia M. Nicolae, George‐Lucian Moldovan, Joshua Straka

CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single-stranded DNA gaps

Nucleic Acids Research(2024)10.1093/nar/gkae998

N/A

0DataRank · unranked

3 citations

Jude B. Khatib, Alexandra Nusawardhana, Joshua Straka, Claudia M. Nicolae, George‐Lucian Moldovan +1 more

CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single stranded DNA gaps

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.17.589988

N/A

0DataRank · unranked

1 citations

Jude B. Khatib, Claudia M. Nicolae, George‐Lucian Moldovan, Lindsey M Pale

Translesion-synthesis-mediated bypass of DNA lesions occurs predominantly behind replication forks restarted by PrimPol

Cell Reports(2025)10.1016/j.celrep.2025.115360

N/A

0DataRank · unranked

4 citations

Julia R. Ambrose, Sonal Garg, Cynthia Lascarez-Espana, Abbey Rebok, Thomas E. Spratt +3 more

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens

Nature Communications(2020)10.1038/s41467-020-19961-w

N/A

0DataRank · unranked

54 citations

Emily M. Schleicher, Tanay Thakar, Anastasia Hale, Ashna Dhoonmoon, Nathanial J. Tolman +8 more

Dual genome-wide CRISPR knockout and CRISPR activation screens identify common mechanisms that regulate the resistance to multiple ATR inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.08.032854

N/A

0DataRank · unranked

1 citations

Ashna Dhoonmoon, Kristen E. Clements, Lindsey M. Jackson, Coryn L. Stump, Claudia M. Nicolae +2 more

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in replication fork stability controlled by ATR

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.08.032847

N/A

0DataRank · unranked

0 citations

Emily M. Schleicher, Claudia M. Nicolae, Kristen E. Clements, George‐Lucian Moldovan, Ashna Dhoonmoon

ADP‐ribosyltransferases, an update on function and nomenclature

FEBS Journal(2021)10.1111/febs.16142

N/A

0DataRank · unranked

330 citations

Ivan Ahel, Matthias Altmeyer, Alan Ashworth, Péter Bai, Paul Chang +42 more

WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells

Nature Communications(2021)10.1038/s41467-021-26811-w

N/A

0DataRank · unranked

51 citations

Kajal Biswas, Joshua A. Sommers, Haley Thompson, Sanket Awate, Claudia M. Nicolae +6 more