Christos Fountzilas

Roswell Park Comprehensive Cancer Center

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 11 papers. Top paper: “A multicentre phase 1b/2 study of tivozanib in patients with advanced inoperable hepatocellular carcinoma”.

A multicentre phase 1b/2 study of tivozanib in patients with advanced inoperable hepatocellular carcinoma

British Journal of Cancer(2020)10.1038/s41416-020-0737-6

N/A

1.1DataRank · unranked

31 citations

Medhavi Gupta, Sunyoung Lee, Smitha Krishnamurthi, Bassam Estfan, Katy Wang +6 more

Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair

Communications Biology(2021)10.1038/s42003-021-02370-0

N/A

0.385DataRank · unranked

12 citations

Moyi Wang, Mohammed Alruwaili, Brandon E. Smith, Megan Melnick, Kevin H. Eng +6 more

Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer

Journal of Pharmaceutical Analysis(2024)10.1016/j.jpha.2024.101001

N/A

0.312DataRank · unranked

7 citations

Wenjie Wu, Li Yan, Leslie Curtin, Melanie M. Farrauto, Sandra Sexton +6 more

Design, synthesis and investigation of biological activity and mechanism of fluoroaryl-substituted derivatives at the FL118 position 7

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.117143

N/A

0.312DataRank · unranked

7 citations

Ruojiong Wang, Lianhao An, Lei Li, Haonan Xiong, Fan Dong +9 more

Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence

Journal of Experimental & Clinical Cancer Research(2023)10.1186/s13046-023-02787-x

N/A

0DataRank · unranked

44 citations

Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze +4 more

Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-0547

N/A

0DataRank · unranked

43 citations

Arwen A. Tisdale, Swati Venkat, Kathryn E. Maraszek, Abdulrahman A. Alahmari, Anthony George +12 more

A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101434

N/A

0DataRank · unranked

16 citations

Justin Zonneville, Maricris N. Naranjo, Hannah Serio, Thomas Melendy, Robert M. Straubinger +9 more

FL118, acting as a ‘molecular glue degrader’, binds to, dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Clinical and Translational Medicine(2022)10.1002/ctm2.881

N/A

0DataRank · unranked

40 citations

Wenjie Wu, Ieman Aljahdali, Jianqun Liao, Sreevidya Santha, Christos Fountzilas +3 more

Sensitivity of colorectal or pancreatic cancers with high DDX5 and mutations in Kras and p53 genes to FL118 treatment.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e16102

N/A

0DataRank · unranked

2 citations

Wenjie Wu, Jianqun Liao, Sreevidya Santha, Leman Aljahdali, Jue Wang +5 more

Role of mutant KRAS as a biomarker in FL118-induced apoptosis, reactive oxygen species (ROS) production and inhibition of survivin, Mcl-1 and XIAP in human bladder cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e15651

N/A

0DataRank · unranked

0 citations

Ieman Aljahdali, Sailee Rasam, Xue Wang, Xiang Ling, Jianqun Liao +6 more

Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer

Cancers(2020)10.3390/cancers12113413

N/A

0DataRank · unranked

22 citations

Xiang Ling, Ieman Aljahdali, Sailee Rasam, Xue Wang, Jianqun Liao +6 more