Nabeel Bardeesy

Also affiliated with Harvard University, Massachusetts General Hospital, Center for Cancer Research

MedicineBiochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery”.

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery

Nature Communications(2021)10.1038/s41467-021-25468-9

N/A

1.1DataRank · unranked

41 citations

Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero +63 more

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

UNC Libraries(2021)10.17615/d9z4-0943

N/A

0.881DataRank · unranked

26 citations

Chun-Xiao Xu, Michael D. Cameron, D. Neil Hayes, Lucian R. Chirieac, Jing Ouyang +38 more

Immunology and immunotherapy of cholangiocarcinoma

Nature Reviews Gastroenterology & Hepatology(2023)10.1038/s41575-022-00741-4

N/A

0.787DataRank · unranked

189 citations

Robert F. Schwabe, Nabeel Bardeesy, Lichun Ma, Lipika Goyal, Robin Kate Kelley +2 more

Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway

Cell(2023)10.1016/j.cell.2023.04.026

N/A

0.748DataRank · unranked

145 citations

Claire Simpson, Jacqueline Berner, Harrison B. Chong, Jiafeng Fang, Zehra Ordulu +33 more

Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms

eLife(2023)10.7554/elife.69521

N/A

0.725DataRank · unranked

32 citations

Samantha Maisel, Yeonjoo Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu +15 more

FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1669

N/A

0.705DataRank · unranked

109 citations

Srivatsan Raghavan, Qibiao Wu, Yvonne Y. Li, Liam F. Spurr, Hersh Gupta +35 more

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

Cell(2024)10.1016/j.cell.2024.03.027

N/A

0.686DataRank · unranked

96 citations

Harrison B. Chong, Siwen Zhang, Tzu-Yi Yang, Matthew J. Lazarov, Stefan Harry +66 more

Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and Is Measurable with Collagen-Targeted Molecular MRI

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-18-1359

N/A

0.621DataRank · unranked

62 citations

Mozhdeh Sojoodi, Martin S. Taylor, Veronica Clavijo Jordan, Christian T. Farrar, Andrea L. Axtell +21 more

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2

Angewandte Chemie International Edition(2021)10.1002/anie.202101328

N/A

0.612DataRank · unranked

58 citations

Jie Jiang, Qibiao Wu, Nathaniel J. Henning, Katherine A. Donovan, Hong Yue +7 more

DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0634

N/A

0.596DataRank · unranked

16 citations

Jinkai Wan, Vajira Weeresekara, Joel Markus Vaz, Giuseppe Tarantino, Tenna Holgersen Bryde +19 more

TBK1 Targeting Is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids

Cancer Immunology Research(2025)10.1158/2326-6066.cir-23-1011

N/A

0.530DataRank · unranked

15 citations

Luke Maggs, Apekshya Panda, Samuel J. Wright, Angelina M. Cicerchia, Anne Jenney +23 more

Oxidation of retromer complex controls mitochondrial translation

Nature(2025)10.1038/s41586-025-08756-y

N/A

0.515DataRank · unranked

30 citations

Md Yousuf Ali, Harrison B. Chong, Pei-Chieh Tien, James Woods, Carolina Noble +30 more

SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers

Nature Cancer(2023)10.1038/s43018-023-00523-0

N/A

0.489DataRank · unranked

25 citations

William Shen, Mindy I. Davis, Ke Kong, Phuong Vu, Supriya K. Saha +34 more

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

UNC Libraries(2020)10.17615/ge7q-0q17

N/A

0.442DataRank · unranked

18 citations

Sean T. Bailey, David J. Kwiatkowski, Pasi A. Jänne, Jeffrey A. Engelman, Julián Carretero +35 more

Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC

Journal of Thoracic Oncology(2023)10.1016/j.jtho.2023.03.014

N/A

0.385DataRank · unranked

12 citations

Christopher S. Nabel, Dezhi Li, Ruth Í. O’Connor, Caroline R. Crosby, Sarah Chang +27 more

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.20.563287

N/A

0.330DataRank · unranked

8 citations

Harrison B. Chong, Siwen Zhang, Matthew J. Lazarov, Stefan Harry, Michelle Maynard +64 more

Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.26.525680

N/A

0.165DataRank · unranked

2 citations

Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Zelong Liu, Sarah M. Shin +17 more

In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1 -mutant lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.18.537350

N/A

0.104DataRank · unranked

1 citations

David H. Peng, David Fenyö, Hao Yuan, Alfonso Lopez, Daniel Levin +26 more

Molecular MRI of Dysregulated Zinc Secretion Detects Pancreatic Ductal Adenocarcinoma and Response to KRAS G12D Inhibitor Treatment

Cancer Research(2025)10.1158/0008-5472.can-24-3384

N/A

0.104DataRank · unranked

1 citations

Mozhdeh Sojoodi, Farzad Moloudi, Patricia Gonzalez Pagan, Manyu Jin, Pamela Pantazopoulos +15 more

Discovery of Chirally-dependent Protein O-2-Hydroxyglutarylation by D2HG and L2HG

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.24.634716

N/A

0.104DataRank · unranked

1 citations

Yi‐Kai Liu, Zhuojun Luo, Meng-Ju Wu, Claudia N. Evans, Zihan Qu +6 more

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

npj Precision Oncology(2022)10.1038/s41698-022-00304-5

N/A

0DataRank · unranked

81 citations

Betty Rouaisnel, Antoine Daina, Srivatsan Raghavan, Lauren A. Roller, Brandon M. Huffman +7 more

NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer

Cell Metabolism(2023)10.1016/j.cmet.2023.01.012

N/A

0DataRank · unranked

145 citations

Maolin Ge, Makiko Hayashi, Magdy Gohar, Cong-Hui Yao, Adriaan de Groot +22 more

EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1168

N/A

0DataRank · unranked

99 citations

Yuanli Zhen, Lei Shi, Phuong Vu, Patricia Greninger, Ramzi Adil +18 more

Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-1317

N/A

0DataRank · unranked

80 citations

Haley Ellis, Giulia Siravegna, Alexa Michel, Bryanna L. Norden, Ferran Fece de la Cruz +7 more

The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer

Annals of Oncology(2022)10.1016/j.annonc.2022.09.150

N/A

0DataRank · unranked

143 citations

Francesco Facchinetti, Daniel DiToro, Islam Baiev, Umair Majeed, Sylvia A. Reyes +24 more

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2

Angewandte Chemie(2021)10.1002/ange.202101328

N/A

0DataRank · unranked

6 citations

Jie Jiang, Qibiao Wu, Nathaniel J. Henning, Katherine A. Donovan, Hong Yue +7 more

Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer

Cell Cycle(2023)10.1080/15384101.2023.2278945

N/A

0DataRank · unranked

18 citations

Xavier Deschênes‐Simard, Stéphane Lopes‐Paciencia, Benjamin Le Calvé, Paloma Kalegari, Lian Mignacca +13 more

Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma

Gut(2021)10.1136/gutjnl-2020-322493

N/A

0DataRank · unranked

81 citations

Koetsu Inoue, Sebastian Klein, Stefan Halvorsen, Jiang Chen, Aya Matsui +28 more

KRAS Wild-Type Pancreatic Cancer: Decoding Genomics, Unlocking Therapeutic Potential

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-2221

N/A

0DataRank · unranked

1 citations

Haley Ellis, Nabeel Bardeesy, Hiroyuki Kato

Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model

UNC Libraries(2020)10.17615/kd0y-5g22

N/A

0DataRank · unranked

0 citations

David B. Darr, Diego H. Castrillón, Jessica A. Sorrentino, Janakiraman Krishnamurthy, Allison M. Deal +5 more

Somatic LKB1 Mutations Promote Cervical Cancer Progression

UNC Libraries(2020)10.17615/f657-sz21

N/A

0DataRank · unranked

0 citations

Esra A. Akbay, David J. Kwiatkowski, Takeshi Shimamura, Shana N. Wingo, Todd Boren +9 more

The LKB1 Tumor Suppressor as a Biomarker in Mouse and Human Tissues

UNC Libraries(2020)10.17615/cbam-0z89

N/A

0DataRank · unranked

0 citations

Diego H. Castrillón, D. Neil Hayes, Nabeel Bardeesy, Song Zhang, Thomas G. Stewart +5 more

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.11.532189

N/A

0DataRank · unranked

0 citations

Claire Simpson, Jacqueline Berner, Harrison B. Chong, Jiafeng Fang, Zehra Ordulu +31 more

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

UNC Libraries(2020)10.17615/wp1b-x790

N/A

0DataRank · unranked

0 citations

Filippos Kottakis, Yvonne Y. Li, Rahul Karnik, Peter S. Hammerman, Alexander Meissner +14 more

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

Science(2024)10.1126/science.adl6173

N/A

0DataRank · unranked

93 citations

Hiroshi Kondo, Ashwin V. Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab +33 more

Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression

Nature Communications(2024)10.1038/s41467-024-48441-8

N/A

0DataRank · unranked

42 citations

Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin +9 more

Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti–PD-1 Therapy

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-0486

N/A

0DataRank · unranked

28 citations

Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Zelong Liu, Sarah M. Shin +20 more

FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma

Nature Communications(2024)10.1038/s41467-024-47514-y

N/A

0DataRank · unranked

28 citations

Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis +8 more

Cholangiocarcinoma Targeted Therapies

American Journal Of Pathology(2024)10.1016/j.ajpath.2024.11.005

N/A

0DataRank · unranked

15 citations

Chiara Braconi, Juan W. Valle, Nabeel Bardeesy, Haley Ellis

The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-3588

N/A

0DataRank · unranked

16 citations

Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L. Norden, Ryan B. Corcoran +11 more

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH -Mutant Molecular Profiles

UNC Libraries(2020)10.17615/7ms0-1a34

N/A

0DataRank · unranked

0 citations

Umadevi Veluvolu, Mario Berríos, David E. Kleiner, Donghui Tan, Johanna Gardner +95 more

Interplay between B7–H3 and HLA class I in the clinical course of pancreatic ductal adenocarcinoma

Cancer Letters(2024)10.1016/j.canlet.2024.216713

N/A

0DataRank · unranked

6 citations

Marco Ventin, Shahrzad Arya, Filippos Kontos, Theodoros Michelakos, Yurie Sekigami +13 more

Genetics and biology of pancreatic ductal adenocarcinoma

Genes & Development(2024)10.1101/gad.351863.124

N/A

0DataRank · unranked

24 citations

Alec C. Kimmelman, Nabeel Bardeesy, Raghu Kalluri, Anirban Maitra, Ronald A. DePinho +1 more

Metformin inhibits nuclear egress of chromatin fragments in senescence and aging

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.16.628669

N/A

0DataRank · unranked

1 citations

Yanxin Xu, Tara C. O’Brien, Ji‐Won Lee, Lu Wang, Murat Çetinbaş +6 more

FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma

UNC Libraries(2024)10.17615/5f1d-kh05

N/A

0DataRank · unranked

0 citations

Eranga R. Balasooriya, Dejan Juric, Kai Liu, Qin Xu, Haley Ellis +8 more

Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

RePEc: Research Papers in Economics(2020)10.17615/aj6w-2b53

N/A

0DataRank · unranked

12 citations

Grit S. Herter-Sprie, Xiaoen Wang, Kwok‐Kin Wong, Carla F. Kim, Anil K. Rustgi +29 more

A human liver cell-based system modeling a clinical prognostic liver signature combined with single cell RNA-seq for discovery of novel liver disease therapeutics

Journal of Hepatology(2020)10.1016/s0168-8278(20)30611-5

N/A

0DataRank · unranked

0 citations

Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Xiaochen Sun +62 more

SAR Studies around the SULT1A1-Activated Alkylator YC-1 as Cytotoxic Agents against Biliary Tract Cancer Cells

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00489

N/A

0DataRank · unranked

0 citations

Wei Zhao, Jonathan H. Shrimp, Marius Vava, Rohan Sinha, Shweta Sharma +17 more

NRF2 activation induces NADH-reductive stress providing a metabolic vulnerability in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.31.506025

N/A

0DataRank · unranked

13 citations

Maolin Ge, Addriaan de Groot, Alexander Carlin, Magdy Gohar, Hannah Fischer +18 more

IFNA pathway drives the more aggressive phenotype of KRAS G12D -mutant pancreatic ductal adenocarcinomas via IFNAR1/STAT3 activation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.29.497540

N/A

0DataRank · unranked

0 citations

Daniel H. Schanne, Aya Matsui, Pin‐Ji Lei, Sebastian Klein, Shuichi Aoki +20 more