🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Richard V. Pearse

Brigham and Women's Hospital

ORCID: 0000-0003-3972-1457

Also affiliated with Harvard University

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile
2.4Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain

Nature Genetics(2024)10.1038/s41588-024-01685-y
Top 9%
2.3DataRank
Top 9%179 citations

Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C. White, Bernard Ng +22 more

Papers

Driven by 18 papers — median percentile 60. Top paper: “Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain”.

Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain

Nature Genetics(2024)10.1038/s41588-024-01685-y
Top 9%
2.3DataRank
Top 9%179 citations

Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C. White, Bernard Ng +22 more

Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.07.515446
N/A
0.808DataRank · unranked
35 citations

Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C. White, Bernard Ng +22 more

CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density

Neuron(2025)10.1016/j.neuron.2025.03.034
N/A
0.698DataRank · unranked
41 citations

Elyssa F L Grogan, Courtney R. Benoit, Richard V. Pearse, Sarah E. Heuer, Tain Luquez +14 more

INPP5D regulates inflammasome activation in human microglia

Nature Communications(2023)10.1038/s41467-023-42819-w
N/A
0.652DataRank · unranked
76 citations

Richard V. Pearse, Aimee J. Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioğlu +12 more

Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1

Cell Reports(2023)10.1016/j.celrep.2023.112994
N/A
0.593DataRank · unranked
51 citations

Aimee J. Aylward, Richard V. Pearse, Alexandra M Lish, Yi‐Chen Hsieh, Zachary M. Augur +17 more

Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late‐Onset Alzheimer's Disease

Glia(2025)10.1002/glia.24677
N/A
0.525DataRank · unranked
19 citations

Richard V. Pearse, Alexandra M Lish, Cheryl Pan, Zachary M. Augur, Gizem Terzioğlu +12 more

Association of AK4 Protein From Stem Cell–Derived Neurons With Cognitive Reserve

Neurology(2022)10.1212/wnl.0000000000201120
N/A
0.495DataRank · unranked
10 citations

Yi‐Chen Hsieh, Richard V. Pearse, Yanling Wang, Vladislav Petyuk, Julie A. Schneider +6 more

Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures

Cell Reports(2025)10.1016/j.celrep.2025.115777
N/A
0.483DataRank · unranked
24 citations

Nancy Ashour, Richard V. Pearse, Paige C. Galle, Gwendolyn A Orme, Sarah E. Heuer +10 more

Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity

Molecular Neurodegeneration(2022)10.1186/s13024-022-00558-4
N/A
0.483DataRank · unranked
24 citations

Joseph Negri, Amy He, Richard V. Pearse, Lei Liu, Duc M. Duong +5 more

Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer’s disease risk gene SORL1

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.25.530017
N/A
0.220DataRank · unranked
3 citations

Aimee J. Aylward, Richard V. Pearse, Yi‐Chen Hsieh, Zachary M. Augur, Courtney R. Benoit +13 more

A proteogenomic tool uncovers protein markers for human microglial states

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.03.31.646212
Top 70%
0.165DataRank
Top 70%2 citations

Alex R. Bautista, John F. Tuddenham, Victoria Marshe, Rebecca Chiu, Yunduo Liu +36 more

INPP5D/SHIP1 regulates inflammasome activation in human microglia

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.25.530025
N/A
0DataRank · unranked
10 citations

Seeley B. Fancher, Richard V. Pearse, Hyo Lee, Matti Lam, Nicholas T. Seyfried +5 more

Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons

Alzheimer s & Dementia(2024)10.1002/alz.13680
N/A
0DataRank · unranked
24 citations

Zachary M. Augur, Mason R. Arbery, Nancy Ashour, Katharine Barrett, Richard V. Pearse +8 more

Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease

Communications Biology(2023)10.1038/s42003-023-04791-5
N/A
0DataRank · unranked
19 citations

Kuixi Zhu, Marc Henrion, Syed Shujaat Ali Zaidi, Branden Lau, Sara Moein +7 more

Predictive Network Analysis Identifies JMJD6 and Other Novel Key Drivers in Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.19.512949
N/A
0DataRank · unranked
0 citations

Kuixi Zhu, Marc Henrion, Syed Shujaat Ali Zaidi, Branden Lau, Sara Moein +7 more

Mosaic loss of Chromosome Y in aged human microglia

Genome Research(2022)10.1101/gr.276409.121
N/A
0DataRank · unranked
39 citations

Richard V. Pearse, Tracy L. Young‐Pearse, Sara Mostafavi, Michael Vermeulen

POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population

Brain(2025)10.1093/brain/awaf221
N/A
0DataRank · unranked
3 citations

Lilia B Sattler, Aimee J. Aylward, Olivia Pembridge, Bella Kim, Christina Muratore +9 more

RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons

Progress in Neurobiology(2022)10.1016/j.pneurobio.2022.102316
N/A
0DataRank · unranked
46 citations

Jacqueline Gerritsen, Mei-Chen Liao, Joanna Widomska, Richard V. Pearse, Forest M. White +4 more