Helen E. Scharfman

Nathan Kline Institute for Psychiatric Research

Also affiliated with New York University

NeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 41 papers. Top paper: “Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy”.

Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy

Neuron(2022)10.1016/j.neuron.2022.07.020

N/A

0.661DataRank · unranked

81 citations

John J. LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A. Siegelbaum +2 more

Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105637

N/A

0.637DataRank · unranked

69 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Advances in understanding hilar mossy cells of the dentate gyrus

Cell and Tissue Research(2018)10.1007/s00441-017-2750-5

N/A

0.621DataRank · unranked

62 citations

Helen E. Scharfman

High‐frequency oscillations ( 250–500 Hz ) in animal models of Alzheimer's disease and two animal models of epilepsy

Epilepsia(2022)10.1111/epi.17462

N/A

0.590DataRank · unranked

50 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Is Plasticity of GABAergic Mechanisms Relevant to Epileptogenesis?

Advances in Experimental Medicine and Biology(2014)10.1007/978-94-017-8914-1_11

N/A

0.578DataRank · unranked

46 citations

Amy R. Brooks-Kayal, Helen E. Scharfman

New Insights and Methods for Recording and Imaging Spontaneous Spreading Depolarizations and Seizure-Like Events in Mouse Hippocampal Slices

Frontiers in Cellular Neuroscience(2021)10.3389/fncel.2021.761423

N/A

0.373DataRank · unranked

11 citations

Helen E. Scharfman, Yiling Lu

Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

eLife(2024)10.7554/elife.89889.4

N/A

0.330DataRank · unranked

8 citations

Karim S. Elayouby, Paige Leary, John J. LaFrancois, David Alcantara‐Gonzalez, Swati Jain +5 more

Increasing adult-born neurons protects mice from epilepsy

eLife(2023)10.7554/elife.90893

N/A

0.269DataRank · unranked

5 citations

John J. LaFrancois, Kasey Gerencer, Justin J. Botterill, Meghan Kennedy, Chiara Criscuolo +2 more

Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.09.579729

N/A

0.171DataRank · unranked

2 citations

Meghan Kennedy, Chiara Criscuolo, Justin J. Botterill, Helen E. Scharfman, David Alcantara‐Gonzalez

Increasing adult-born neurons protects mice from epilepsy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.08.548217

N/A

0.165DataRank · unranked

2 citations

John J. LaFrancois, Kasey Gerencer, Justin J. Botterill, Meghan Kennedy, Chiara Criscuolo +2 more

Evidence that cholinergic mechanisms contribute to hyperexcitability at early stages in Alzheimer’s disease

Frontiers in Dementia(2025)10.3389/frdem.2025.1513144

N/A

0.165DataRank · unranked

2 citations

Korey Kam, Áine Duffy, John J. LaFrancois, Paige Leary, Elissavet Chartampila +3 more

Dentate Gyrus Granule Cells Show Stability of BDNF Protein Expression in Mossy Fiber Axons with Age, and Resistance to Alzheimer’s Disease Neuropathology in a Mouse Model

eNeuro(2023)10.1523/eneuro.0192-23.2023

N/A

0.165DataRank · unranked

2 citations

Elissavet Chartampila, Stephen D. Ginsberg, Helen E. Scharfman, Chiara Criscuolo

Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer’s Disease

Journal of Neuroscience(2025)10.1523/jneurosci.0049-25.2025

N/A

0.104DataRank · unranked

1 citations

Jin Park, Umberto Tosi, Francisco A. Blanco, Manuel Silva‐Pérez, Kavitha Muralidharan +9 more

Enhanced excitability of the hippocampal CA2 region and its contribution to seizure generation in a mouse model of temporal lobe epilepsy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.02.478736

N/A

0.104DataRank · unranked

1 citations

John J. LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A. Siegelbaum +2 more

Interictal Spikes in Alzheimer’s Disease: Preclinical Evidence for Dominance of the Dentate Gyrus and Cholinergic Control by Medial Septum

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.24.537999

N/A

0DataRank · unranked

0 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer’s disease neuropathology in a mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.07.539742

N/A

0DataRank · unranked

0 citations

Elissavet Chartampila, Stephen D. Ginsberg, Helen E. Scharfman, Chiara Criscuolo

Reviewer #2 (Public Review): Increasing adult neurogenesis protects mice from epilepsy

(2023)10.7554/elife.90893.1.sa0

N/A

0DataRank · unranked

0 citations

John J. LaFrancois, Kasey Gerencer, Justin J. Botterill, Meghan Kennedy, Chiara Criscuolo +2 more

Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions

Frontiers in Neuroscience(2020)10.3389/fnins.2020.00472

N/A

0DataRank · unranked

22 citations

Chia-Hsuan Fu, Corey P. St. Romain, Yi Zheng, Justin J. Botterill, Helen E. Scharfman +3 more

Towards an Understanding of the Dentate Gyrus Hilus

Hippocampus(2024)10.1002/hipo.23677

N/A

0DataRank · unranked

8 citations

Helen E. Scharfman

Increasing adult-born neurons protects mice from epilepsy

eLife(2024)10.7554/elife.90893.3

N/A

0DataRank · unranked

2 citations

John J. LaFrancois, Kasey Gerencer, Justin J. Botterill, Meghan Kennedy, Chiara Criscuolo +2 more

Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

eLife(2024)10.7554/elife.89889

N/A

0DataRank · unranked

5 citations

Karim S. Elayouby, Paige Leary, John J. LaFrancois, David Alcantara‐Gonzalez, Swati Jain +5 more

Field EPSPs of Dentate Gyrus Granule Cells Studied by Selective Optogenetic Activation of Hilar Mossy Cells in Hippocampal Slices

Hippocampus(2024)10.1002/hipo.23652

N/A

0DataRank · unranked

2 citations

Yiling Lu, Justin J. Botterill, Áine Duffy, John J. LaFrancois, Helen E. Scharfman +1 more

eLife Assessment: On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy

(2024)10.7554/elife.101859.1.sa4

N/A

0DataRank · unranked

0 citations

Helen E. Scharfman

Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer’s disease

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01747-1

N/A

0DataRank · unranked

4 citations

Meghan Kennedy, Chiara Criscuolo, Justin J. Botterill, Helen E. Scharfman, David Alcantara‐Gonzalez

Opposing interictal dynamics in Alzheimer’s disease and epilepsy

Progress in Neurobiology(2025)10.1016/j.pneurobio.2025.102844

N/A

0DataRank · unranked

3 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats

Cell Reports(2025)10.1016/j.celrep.2025.115952

N/A

0DataRank · unranked

1 citations

John J. LaFrancois, Vanessa A. Skucas, Daniel J. Friedman, André A. Fenton, Dino Dvořák +3 more

Adenosine Makes a Scene

Epiliepsy currents/Epilepsy currents(2025)10.1177/15357597251323126

N/A

0DataRank · unranked

0 citations

Helen E. Scharfman

Increasing adult neurogenesis protects mice from epilepsy

(2023)10.7554/elife.90893.1

N/A

0DataRank · unranked

0 citations

John J. LaFrancois, Kasey Gerencer, Justin J. Botterill, Meghan Kennedy, Chiara Criscuolo +2 more

Endocrine Insights into the Pathophysiology of Autism Spectrum Disorder

The Neuroscientist(2020)10.1177/1073858420952046

N/A

0DataRank · unranked

23 citations

Carolyn Elaine Creighton, Helen E. Scharfman, Elena Choleris, Neil J. MacLusky, Hayley A. Wilson

WITHDRAWN: Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.06.137844

N/A

0DataRank · unranked

6 citations

Yiling Lu, Paige Leary, Swati Jain, John J. LaFrancois, Clay Lacefield +3 more

Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer’s disease neuropathology and atypical effects of the cholinergic antagonist atropine

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.30.321646

N/A

0DataRank · unranked

2 citations

Elissavet Chartampila, Helen E. Scharfman, David Alcantara‐Gonzalez

Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice

Journal of Neuroscience(2021)10.1523/jneurosci.1724-20.2021

N/A

0DataRank · unranked

63 citations

K. Yaragudri Vinod, Kathleen J. Gerencer, Cátia M. Teixeira, John J. LaFrancois, Helen E. Scharfman +1 more

Dorsal and ventral mossy cells differ in their axonal projections throughout the dentate gyrus of the mouse hippocampus

Hippocampus(2021)10.1002/hipo.23314

N/A

0DataRank · unranked

61 citations

Kathleen J. Gerencer, K. Yaragudri Vinod, David Alcantara‐Gonzalez, Helen E. Scharfman, Justin J. Botterill

Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine

Neurobiology of Disease(2021)10.1016/j.nbd.2021.105274

N/A

0DataRank · unranked

30 citations

Elissavet Chartampila, Chiara Criscuolo, Helen E. Scharfman, David Alcantara‐Gonzalez

Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.28.450253

N/A

0DataRank · unranked

9 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

High Frequency Oscillations (250-500Hz) in Animal Models of Alzheimer’s Disease and Two Animal Models of Epilepsy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.30.498284

N/A

0DataRank · unranked

3 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Assessments of dentate gyrus function: discoveries and debates

Nature reviews. Neuroscience(2023)10.1038/s41583-023-00710-z

N/A

0DataRank · unranked

140 citations

Steve Ramirez, Alessandro Treves, Inah Lee, Helen E. Scharfman, Craig E.L. Stark +3 more

Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum

Neurobiology of Disease(2023)10.1016/j.nbd.2023.106294

N/A

0DataRank · unranked

26 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras

Reduced Cholecystokinin-Expressing Interneuron Input Contributes to Disinhibition of the Hippocampal CA2 Region in a Mouse Model of Temporal Lobe Epilepsy

Journal of Neuroscience(2023)10.1523/jneurosci.2091-22.2023

N/A

0DataRank · unranked

13 citations

Bina Santoro, Anastasia Barnett, Christos Panagiotis Lisgaras, Helen E. Scharfman, Steven A. Siegelbaum +1 more

Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.12.540428

N/A

0DataRank · unranked

1 citations

Karim S. Elayouby, Paige Leary, John J. LaFrancois, David Alcantara‐Gonzalez, Swati Jain +5 more

High Frequency Oscillations (>250Hz) Outnumber Interictal Spikes in Preclinical Studies of Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.30.564797

N/A

0DataRank · unranked

1 citations

Helen E. Scharfman, Christos Panagiotis Lisgaras