Avner Schlessinger

Biochemistry, Genetics and Molecular BiologyComputer ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.483Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A web portal for exploring kinase-substrate interactions

npj Systems Biology and Applications(2024)10.1038/s41540-024-00442-5

Top 50%

0.353DataRank

Top 50%5 citations

Yan Chak Li, Avner Schlessinger, Gaurav Pandey, John A. P. Sekar

Papers

Driven by 37 papers — median percentile 15. Top paper: “Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set”.

Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Genome Medicine(2023)10.1186/s13073-023-01261-9

N/A

0.999DataRank · unranked

50 citations

Meltem Ece Kars, Yiming Wu, Çiğdem Sevim Bayrak, Peter D. Stenson, D.N. Cooper +3 more

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009302

N/A

0.911DataRank · unranked

16 citations

Minji Jeon, Robert J. Allaway, Jaewoo Kang, Donghyeon Park, Jinhyuk Lee +17 more

Crowdsourced mapping of unexplored target space of kinase inhibitors

Nature Communications(2021)10.1038/s41467-021-23165-1

N/A

0.675DataRank · unranked

89 citations

Balaguru Ravikumar, Robert J. Allaway, Fang Wan, Sung‐Joon Park, Olexandr Isayev +94 more

Targeting SLC transporters: small molecules as modulators and therapeutic opportunities

Trends in Biochemical Sciences(2023)10.1016/j.tibs.2023.05.011

N/A

0.657DataRank · unranked

79 citations

Nicole Zatorski, Keino Hutchinson, Claire Colas, Avner Schlessinger

Rational design of ASCT2 inhibitors using an integrated experimental-computational approach

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104093118

N/A

0.624DataRank · unranked

63 citations

Elias Ndaru, Alisa A. Garaeva, Yueyue Shi, Laura Zielewicz, Paul Zakrepine +6 more

Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.10.007

N/A

0.612DataRank · unranked

58 citations

David Stein, Aayushee Jain, Kumardeep Chaudhary, Girish N. Nadkarni, Tielman Van Vleck +8 more

Identification of a G-Protein-Independent Activator of GIRK Channels

Cell Reports(2020)10.1016/j.celrep.2020.107770

N/A

0.553DataRank · unranked

39 citations

Peter M.U. Ung, Gergely Zahoránszky-Köhalmi, Alexey Zakharov, Natalia J. Martinez, Anton Simeonov +6 more

Crowdsourced mapping extends the target space of kinase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2019.12.31.891812

N/A

0.552DataRank · unranked

11 citations

Balaguru Ravikumar, Robert J. Allaway, Sung‐Joon Park, Fang Wan, Olexandr Isayev +22 more

Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2210247119

N/A

0.538DataRank · unranked

35 citations

Gregory McInnes, Julia E. H. Brown, Neil Thomas, Keino Hutchinson, Marcus Y. Chin +8 more

Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score

Nature Communications(2024)10.1038/s41467-024-53333-y

N/A

0.385DataRank · unranked

12 citations

Áine Duffy, Ben Omega Petrazzini, Ha My T. Vy, David Stein, Matthew Mort +8 more

A web portal for exploring kinase-substrate interactions

npj Systems Biology and Applications(2024)10.1038/s41540-024-00442-5

Top 50%

0.353DataRank

Top 50%5 citations

Yan Chak Li, Avner Schlessinger, Gaurav Pandey, John A. P. Sekar

Expanding the utility of variant effect predictions with phenotype-specific models

Nature Communications(2025)10.1038/s41467-025-66607-w

N/A

0.292DataRank · unranked

6 citations

Meltem Ece Kars, Baptiste Milisavljevic, Matthew Mort, Peter D. Stenson, Jean-Laurent Casanova +6 more

Mavacamten improves symptoms in obstructive hypertrophic cardiomyopathy patients

Trends in Pharmacological Sciences(2023)10.1016/j.tips.2023.02.005

N/A

0.269DataRank · unranked

5 citations

Eric A. Sobie, Avner Schlessinger, Nicole Zatorski

Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer

iScience(2024)10.1016/j.isci.2024.110640

N/A

0.165DataRank · unranked

2 citations

Yifei Sun, Christian Dallago, Timothy Karl, David Stein, Burkhard Rost +6 more

KinAce: a web portal for exploring kinase-substrate interactions

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.08.570875

Top 71%

0.130DataRank

Top 71%1 citations

Yan Chak Li, Avner Schlessinger, Gaurav Pandey, John A. P. Sekar

Structural Analysis of Genomic and Proteomic Signatures Reveal Dynamic Expression of Intrinsically Disordered Regions in Breast Cancer and Tissue

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.23.529755

N/A

0.104DataRank · unranked

1 citations

Yifei Sun, Abdülkadir Elmas, Christian Dallago, Timothy Karl, David Stein +5 more

KinAce web portal and dataset of kinase-substrate interactions

Zenodo (CERN European Organization for Nuclear Research)(2023)10.5281/zenodo.10212986

Top 100%

0DataRank

Top 100%0 citations

Yan Chak Li, Avner Schlessinger, Gaurav Pandey, John A. P. Sekar

Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications

Nature Genetics(2024)10.1038/s41588-023-01609-2

N/A

0DataRank · unranked

32 citations

Ben Omega Petrazzini, David Stein, Joshua K. Park, Iain S. Forrest, Kyle Gibson +12 more

A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012302

N/A

0DataRank · unranked

18 citations

Yan Chak Li, David Stein, Gaurav Pandey, Avner Schlessinger, Noah B. Herrington

A critical residue mediates proper assembly and gating of GIRK2 channels

The Journal of General Physiology(2025)10.1085/jgp.202513817

N/A

0DataRank · unranked

1 citations

Jonathan Mount, Keino Hutchinson, Yihan Zhao, Yulin Zhao, Ian W. Glaaser +4 more

Genetic evidence informs the direction of therapeutic modulation in drug development

npj Drug Discovery.(2025)10.1038/s44386-025-00027-0

N/A

0DataRank · unranked

2 citations

Áine Duffy, Joshua K. Park, David Stein, Avner Schlessinger, Yuval Itan +6 more

Development of a genetic priority score to predict drug side effects using human genetic evidence

Nature Communications(2025)10.1038/s41467-025-63762-y

N/A

0DataRank · unranked

1 citations

Robert Chen, David Stein, Joshua K. Park, Matthew Mort, Marie Verbanck +7 more

Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions

Medicinal Research Reviews(2020)10.1002/med.21764

N/A

0DataRank · unranked

415 citations

Avner Schlessinger, Daniel Wacker, H. Ümit Kanıskan, Jian Jin, Ming‐Ming Zhou +2 more

Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity

Nature Communications(2020)10.1038/s41467-020-18396-7

N/A

0DataRank · unranked

51 citations

Rayees Rahman, Jens Hansen, Alan D. Stern, Jaehee V. Shim, Arjun S. Yadaw +12 more

Ligand discovery from a dopamine D3 receptor homology model and crystal structure

UNC Libraries(2020)10.17615/e45z-q037

N/A

0DataRank · unranked

0 citations

Avner Schlessinger, Brian K. Shoichet, Hao Fan, Jens Carlsson, John J. Irwin +4 more

An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters

Frontiers in Pharmacology(2021)10.3389/fphar.2021.722889

N/A

0DataRank · unranked

71 citations

Tabea Wiedmer, Álvaro Inglés‐Prieto, Patrick Altermatt, Helena Batoulis, Felix Bärenz +26 more

Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1351

N/A

0DataRank · unranked

65 citations

Tamer A. Ahmed, Maxwell R. Tucker, Peter M.U. Ung, Min Xiao, Zoi Karoulia +12 more

Protein structure–based gene expression signatures

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2014866118

N/A

0DataRank · unranked

8 citations

Nicole Zatorski, Jens Hansen, Yuguang Xiong, J. G. Coen van Hasselt, Eric A. Sobie +5 more

Type II Binders Targeting the “GLR-Out” Conformation of the Pseudokinase STRADα

Biochemistry(2021)10.1021/acs.biochem.0c00714

N/A

0DataRank · unranked

7 citations

Z.M. Khan, Peter M.U. Ung, Alex P. Scopton, Lisa Silber, Seshat M. Mack +4 more

Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations

Biophysical Journal(2022)10.1016/j.bpj.2022.11.001

N/A

0DataRank · unranked

15 citations

Dina Buitrago Silva, Joshua Bohlke, Chase Clausen, Allen A. Thomas, Massimiliano Bonomi +2 more

Alanine serine cysteine transporter (ASCT) substrate binding site properties probed with hydroxyhomoserine esters

Journal of Physical Organic Chemistry(2022)10.1002/poc.4347

N/A

0DataRank · unranked

6 citations

Laura Zielewicz, Yueyue Shi, Keino Hutchinson, Rachel‐Ann A. Garibsingh, Avner Schlessinger +2 more

Structural signatures: a web server for exploring a database of and generating protein structural features from human cell lines and tissues

Database(2022)10.1093/database/baac053

N/A

0DataRank · unranked

3 citations

David Stein, Rayees Rahman, Ravi Iyengar, Avner Schlessinger, Nicole Zatorski

Substrate Binding and Inhibition of the Anion Exchanger 1 Transporter

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.11.480130

N/A

0DataRank · unranked

4 citations

Shifan Yang, Stone AC, Sezen Vatansever, Gregory Zilberg, Yamuna Kalyani Mathiharan +8 more

Substrate binding and inhibition of the anion exchanger 1 transporter

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-01085-6

N/A

0DataRank · unranked

31 citations

Shifan Yang, Stone AC, Sezen Vatansever, Gregory Zilberg, Yamuna Kalyani Mathiharan +9 more

Conserved allosteric inhibition mechanism in SLC1 transporters

eLife(2023)10.7554/elife.83464

N/A

0DataRank · unranked

16 citations

Jiali Wang, Rachel‐Ann A. Garibsingh, Keino Hutchinson, Yueyue Shi, Gilad Eisenberg +4 more

Data from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

(2023)10.1158/2159-8290.c.6549364

N/A

0DataRank · unranked

1 citations

Tamer A. Ahmed, Maxwell R. Tucker, Peter M.U. Ung, Min Xiao, Zoi Karoulia +12 more

KinAce web portal and dataset of kinase-substrate interactions

Zenodo (CERN European Organization for Nuclear Research)(2023)10.5281/zenodo.10212985

Top 100%

0DataRank

Top 100%0 citations

Yan Chak Li, Avner Schlessinger, Gaurav Pandey, John A. P. Sekar

Avner Schlessinger

Indexed papers

Top data-sharing exemplar

Papers