Charles Karan

Biochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.6Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1020

Top 20%

1.0DataRank

Top 20%43 citations

Filemon S. Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Allison R. Rainey +50 more

Papers

Driven by 26 papers — median percentile 74. Top paper: “The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies”.

The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies

eLife(2020)10.7554/elife.52707

N/A

1.4DataRank · unranked

41 citations

Mehmet Eren Ahsen, Thomas Schaffter, Xintong Chen, Ronald Realubit, Charles Karan +4 more

A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1020

Top 20%

1.0DataRank

Top 20%43 citations

Filemon S. Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Allison R. Rainey +50 more

A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.21.423514

Top 32%

0.625DataRank

Top 32%20 citations

Robert J. Allaway, Bence Szalai, Wenyu Wang, Tingzhong Tian, Adrià Fernández‐Torras +23 more

TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-0312

N/A

0.345DataRank · unranked

9 citations

Junfei Zhao, Lu Wang, Subhas Mukherjee, Daniel Y. Zhang, Víctor A. Arrieta +23 more

Discovering Venom-Derived Drug Candidates Using Differential Gene Expression

Toxins(2023)10.3390/toxins15070451

N/A

0.312DataRank · unranked

7 citations

Hai Li, Tanya Napolitano, Ronald Realubit, Charles Karan, Mandë Holford +2 more

Systematic Elucidation and Pharmacological Targeting of Tumor-Infiltrating Regulatory T Cell Master Regulators

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.22.481404

N/A

0.292DataRank · unranked

6 citations

Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Christopher M. Jackson +10 more

Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.15.528736

N/A

0.241DataRank · unranked

4 citations

Wenxue Li, Mikko Turunen, Jing He, Prem S. Subramaniam, Sergey Pampou +8 more

Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.11.617898

N/A

0.104DataRank · unranked

1 citations

Heeju Noh, Lorenzo Tomassoni, Danting Cao, Yizhou Zhou, Ke Xiao +8 more

A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection

Communications Biology(2022)10.1038/s42003-022-03663-8

N/A

0DataRank · unranked

8 citations

Megan L. Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Patricio Doldan +11 more

OncoLoop: A network-based precision cancer medicine framework

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.11.479456

N/A

0DataRank · unranked

3 citations

Min Zou, Juan Martín Arriaga, Francisca Nunes de Almeida, Eugene F. Douglass, Maho Shibata +15 more

A Model for Network-Based Identification and Pharmacological Targeting of Aberrant, Replication-Permissive Transcriptional Programs Induced by Viral Infection

Research Square(2022)10.21203/rs.3.rs-1287631/v1

N/A

0DataRank · unranked

0 citations

Megan L. Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Patricio Doldan +11 more

Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators

Cancer Cell(2023)10.1016/j.ccell.2023.04.003

N/A

0DataRank · unranked

58 citations

Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Alina C. Iuga +16 more

A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529581

N/A

0DataRank · unranked

3 citations

Athanassios Dovas, Michael Argenziano, Wenting Zhao, Henar Cuervo, Dominique Higgins +20 more

Compound Mechanism of Action and Polypharmacology can be Elucidated by Large-Scale Perturbational Profile Analysis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.08.561457

N/A

0DataRank · unranked

1 citations

Tal Hirschhorn, Eugene F. Douglass, Diana Murray, Stephen J. Trudeau, Mikko Turunen +13 more

A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

The EMBO Journal(2024)10.1038/s44318-024-00176-4

N/A

0DataRank · unranked

26 citations

Athanassios Dovas, Michael Argenziano, Wenting Zhao, Colin Sperring, Henar Cuervo +25 more

Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis

Nature Communications(2024)10.1038/s41467-024-47957-3

N/A

0DataRank · unranked

12 citations

Wenxue Li, Mikko Turunen, Jing He, Prem S. Subramaniam, Sergey Pampou +8 more

Multiwell-based G0-PCC assay for radiation biodosimetry

Scientific Reports(2024)10.1038/s41598-024-69243-4

N/A

0DataRank · unranked

2 citations

Igor Shuryak, Brian Ponnaiya, Mikhail Repin, Sergey Pampou, Charles Karan +4 more

Identification and targeting of regulators of SARS-CoV-2–host interactions in the airway epithelium

Science Advances(2025)10.1126/sciadv.adu2079

N/A

0DataRank · unranked

1 citations

Heeju Noh, Lorenzo Tomassoni, Dianbo Cao, Yizhuo Zhou, Xiangyi Ke +8 more

Systematic elucidation and pharmacologic targeting of non-oncogene dependencies in imatinib-resistant gastrointestinal stromal tumor

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.12.681609

N/A

0DataRank · unranked

0 citations

Adina Grunn, Arsenije Kojadinovic, Charles Karan, Ronald Realubit, Cristina I. Caescu +9 more

The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.12.091256

N/A

0DataRank · unranked

19 citations

Gideon Bosker, Xiaoyun Sun, Yao Shen, Eugene F. Douglass, Charles Karan +5 more

Pre-clinical validation of an RNA-based precision oncology platform for patient-therapy alignment in a diverse set of human malignancies resistant to standard treatments

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.03.462951

N/A

0DataRank · unranked

7 citations

Filemon S. Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Allison R. Rainey +48 more

Network-based identification and pharmacological targeting of host cell master regulators induced by SARS-CoV-2 infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.03.451001

N/A

0DataRank · unranked

0 citations

Megan L. Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Patricio Doldan +11 more

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Nature Communications(2022)10.1038/s41467-022-29413-2

N/A

0DataRank · unranked

96 citations

Sho Iketani, Arie Zask, Nisha Khanizeman, Eva Bednářová, F. Forouhar +27 more

A community challenge for a pancancer drug mechanism of action inference from perturbational profile data

Cell Reports Medicine(2022)10.1016/j.xcrm.2021.100492

N/A

0DataRank · unranked

69 citations

Robert J. Allaway, Bence Szalai, Wenyu Wang, Tingzhong Tian, Adrià Fernández‐Torras +23 more

OncoLoop: A Network-Based Precision Cancer Medicine Framework

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0342

N/A

0DataRank · unranked

36 citations

Juan Martín Arriaga, Francisca Nunes de Almeida, Min Zou, Eugene F. Douglass, Florencia Picech +19 more

Validation of a High-Throughput Dicentric Chromosome Assay Using Complex Radiation Exposures

Radiation Research(2022)10.1667/rade-22-00007.1

N/A

0DataRank · unranked

10 citations

Mikhail Repin, Adayabalam S. Balajee, Igor Shuryak, Sergey Pampou, Charles Karan +8 more

Charles Karan

Indexed papers

Top data-sharing exemplar

Papers