Cynthia L. Sears

Also affiliated with Johns Hopkins University, Hawaii Pacific University, Johns Hopkins Medicine, Sidney Kimmel Cancer Center, Sidney Kimmel Comprehensive Cancer Center, University of Baltimore

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.262Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.426044

Top 59%

0.262DataRank

Top 59%3 citations

Eliot T. McKinley, Alan J. Simmons, Marisol Ramirez‐Solano, Xiangzhu Zhu, Austin N. Southard-Smith +23 more

Papers

Driven by 41 papers — median percentile 41. Top paper: “Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies”.

Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies

Gastroenterology(2022)10.1053/j.gastro.2022.06.054

N/A

2.5DataRank · unranked

109 citations

Rong Zhong, Tomotaka Ugai, Melissa Zhao, Koichiro Haruki, Naohiko Akimoto +27 more

Bacterial Genotoxin Accelerates Transient Infection–Driven Murine Colon Tumorigenesis

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0912

N/A

1.4DataRank · unranked

58 citations

Kai Fu, Eric M. Wier, Yifan Lei, Andrea Hodgson, Dongqing Xu +7 more

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Cell(2021)10.1016/j.cell.2021.11.031

N/A

0.871DataRank · unranked

332 citations

Cherie’ R. Scurrah, Eliot T. McKinley, Alan J. Simmons, Marisol A. Ramirez-Solano, Xiangzhu Zhu +48 more

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1273

N/A

0.741DataRank · unranked

139 citations

Jie Chen, Nicholas O. Markham, Reece J. Knippel, Jada C. Domingue, Ada Tam +26 more

Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0770

N/A

0.677DataRank · unranked

90 citations

James R. White, Liam Chung, Alyssa Wenzel, Jessica Hicks, Ada Tam +17 more

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

Communications Biology(2021)10.1038/s42003-021-02014-3

N/A

0.581DataRank · unranked

47 citations

Payam Fathi, W. Brian Dalton, Ben Park, Xinqun Wu, David L. Huso +10 more

A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-4834

N/A

0.581DataRank · unranked

47 citations

James R. White, Joell J. Gills, Taiki Hakozaki, Corentin Richard, Bertrand Routy +10 more

Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer

npj Biofilms and Microbiomes(2025)10.1038/s41522-025-00717-7

N/A

0.571DataRank · unranked

44 citations

Zam Cing, Hana Minsky, Asmita Nandi, Taylor Southward, Jacqueline Ferri +10 more

The Microbiome Colorectal Cancer Puzzle: Initiator, Propagator, and Avenue for Treatment and Research

Journal of the National Comprehensive Cancer Network(2021)10.6004/jnccn.2021.7062

N/A

0.545DataRank · unranked

13 citations

Cynthia L. Sears, Reece J. Knippel

Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin‐induced colon epithelial cell signaling

The FASEB Journal(2020)10.1096/fj.202001669r

N/A

0.524DataRank · unranked

32 citations

Jawara Allen, Isabella Posey, Jeremy J.P. Shaw, Pedro Costa‐Pinheiro, Susan J. Walker +8 more

Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors

Cancer Immunology Immunotherapy(2022)10.1007/s00262-022-03169-6

N/A

0.515DataRank · unranked

30 citations

Joell J. Gills, Fuad Mohammad, James R. White, Courtney Stevens, Hua Ding +15 more

An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk

Gastroenterology(2024)10.1053/j.gastro.2024.07.040

N/A

0.477DataRank · unranked

23 citations

Chun‐Han Lo, Raaj S. Mehta, Long H. Nguyen, Yiqing Wang, Wenjie Ma +21 more

Fecal Microbiome Composition Correlates with Pathologic Complete Response in Patients with Operable Esophageal Cancer Treated with Combined Chemoradiotherapy and Immunotherapy

Cancers(2024)10.3390/cancers16213644

N/A

0.360DataRank · unranked

10 citations

Seoho Lee, James R. White, Yujie Zhao, Jacqueline T. Ferri, Gavin Pereira +21 more

Longitudinal Bile Acid Composition Changes Following Faecal Microbiota Transplantation for Clostridioides difficile Infection in Children With and Without Underlying Inflammatory Bowel Disease

Journal of Crohn s and Colitis(2023)10.1093/ecco-jcc/jjad057

N/A

0.360DataRank · unranked

10 citations

Maria Oliva‐Hemker, Arielle Radin, Melissa Weidner, Brynn O’Laughlin, Cynthia L. Sears +3 more

Fecal transplant from vaginally seeded infants decreases intraabdominal adiposity in mice

Gut Microbes(2024)10.1080/19490976.2024.2353394

N/A

0.305DataRank · unranked

5 citations

Curtis Tilves, Hua Ding, Shaoguang Wu, Jada C. Domingue, Camilo A. Ruiz-Bedoya +12 more

Microbial Diagnostics for Cancer: A Step Forward but Not Prime Time Yet

Cancer Cell(2020)10.1016/j.ccell.2020.04.010

N/A

0.269DataRank · unranked

5 citations

Steven L. Salzberg, Cynthia L. Sears

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.426044

Top 59%

0.262DataRank

Top 59%3 citations

Eliot T. McKinley, Alan J. Simmons, Marisol Ramirez‐Solano, Xiangzhu Zhu, Austin N. Southard-Smith +23 more

Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.01.462481

N/A

0.241DataRank · unranked

4 citations

Daniel R. Monaco, Athena Chen, Thiagarajan Venkataraman, Sahana Jayaraman, Cristian Valencia +20 more

Epidemiology of bacterial biofilms on polyps and normal tissues in a screening colonoscopy cohort

Gut Microbes(2025)10.1080/19490976.2025.2452233

N/A

0DataRank · unranked

2 citations

Samara Rifkin, Madison McMann, Sara Glass, Emma Spence, Caroline R. Wensel +26 more

Gut microbiome features associate with immune checkpoint inhibitor response in individuals with non-melanoma skin cancers: an exploratory study

Microbiology Spectrum(2025)10.1128/spectrum.02559-24

N/A

0DataRank · unranked

1 citations

Jacqueline T. Ferri, James R. White, Megan D. Schollenberger, Kim Peloza, Cynthia L. Sears +3 more

Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2024.12.30.630810

N/A

0DataRank · unranked

2 citations

Zam Cing, Hana Minsky, Asmita Nandi, Taylor Southward, Jacqueline Ferri +10 more

Murine gut microbiota dysbiosis via enteric infection modulates the foreign body response to a distal biomaterial implant

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.13.632473

N/A

0DataRank · unranked

1 citations

Natalie Rutkowski, Anna Ruta, Elise Gray-Gaillard, David R. Maestas, Sean H. Kelly +19 more

Antibiotic-induced microbiota depletion impairs the pro-regenerative response to a biological scaffold in mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.23.661121

N/A

0DataRank · unranked

1 citations

Brenda Yang, Elise Gray-Gaillard, Anna Ruta, Joscelyn C. Mejías, Michael Patatanian +9 more

Cooperation Between Genotoxic Bacteria Accelerates Tumorigenesis in a Mouse Model of Colon Carcinogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.18.649375

N/A

0DataRank · unranked

0 citations

Alix Piessevaux, Urvija Rajpal, Jeremy Fisher, Matthew P. Spindler, Zhihua Li +16 more

Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

JCI Insight(2020)10.1172/jci.insight.140978

N/A

0DataRank · unranked

58 citations

Azra Frkatović-Hodžić, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu +10 more

Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps

Cancer Prevention Research(2021)10.1158/1940-6207.capr-20-0664

N/A

0DataRank · unranked

12 citations

Samara Rifkin, Julia L. Drewes, Gerard E. Mullin, Emma Spence, Linda M. Hylind +7 more

Meta‐analysis methods for multiple related markers: Applications to microbiome studies with the results on multiple α‐diversity indices

Statistics in Medicine(2021)10.1002/sim.8940

N/A

0DataRank · unranked

6 citations

Susan Tuddenham, Cynthia L. Sears, Ni Zhao, Hyunwook Koh

Next-generation sequencing: insights to advance clinical investigations of the microbiome

Journal of Clinical Investigation(2022)10.1172/jci154944

N/A

0DataRank · unranked

418 citations

Jennifer L. Pluznick, Steven L. Salzberg, Cynthia L. Sears, Caroline R. Wensel

Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models

mBio(2022)10.1128/mbio.02991-21

N/A

0DataRank · unranked

58 citations

Jada C. Domingue, James R. White, Courtney Stevens, Barath Udayasuryan, Tam T. D. Nguyen +12 more

Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses

Immunity(2022)10.1016/j.immuni.2022.05.002

N/A

0DataRank · unranked

42 citations

Daniel R. Monaco, Athena Chen, Thiagarajan Venkataraman, Sahana Jayaraman, Cristian Valencia +22 more

Adult-Attained Height and Colorectal Cancer Risk: A Cohort Study, Systematic Review, and Meta-Analysis

Cancer Epidemiology Biomarkers & Prevention(2022)10.1158/1055-9965.epi-21-0398

N/A

0DataRank · unranked

11 citations

Lin Wang, Celina N. Santiago, Julie Nanavati, Samara Rifkin, Emma Spence +10 more

The Role of the Gut Microbiome in Cancer: A Review, With Special Focus on Colorectal Neoplasia and Clostridioides difficile

Clinical Infectious Diseases(2023)10.1093/cid/ciad640

N/A

0DataRank · unranked

24 citations

Cynthia L. Sears, Sean M. Anderson

Unraveling the Link between Periodontitis and Inflammatory Bowel Disease: Challenges and Outlook

arXiv (Cornell University)(2023)10.48550/arxiv.2308.10907

N/A

0DataRank · unranked

9 citations

Jeba Mercy Gnanasekaran, Devon L. Allison, Ling-Shiang Chuang, Xuesong He, Mario Aimetti +10 more

Data from A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors

(2023)10.1158/1078-0432.c.6530814

N/A

0DataRank · unranked

0 citations

James R. White, Joell J. Gills, Taiki Hakozaki, Corentin Richard, Bertrand Routy +10 more

Data from A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors

(2023)10.1158/1078-0432.c.6530814.v1

N/A

0DataRank · unranked

0 citations

James R. White, Joell J. Gills, Taiki Hakozaki, Corentin Richard, Bertrand Routy +10 more

Data from Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy

(2023)10.1158/2159-8290.c.6549334.v1

N/A

0DataRank · unranked

0 citations

James R. White, Liam Chung, Alyssa Wenzel, Jessica Hicks, Ada Tam +17 more

Data from Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy

(2023)10.1158/2159-8290.c.6549334

N/A

0DataRank · unranked

0 citations

James R. White, Liam Chung, Alyssa Wenzel, Jessica Hicks, Ada Tam +17 more

Unravelling the Oral–Gut Axis: Interconnection Between Periodontitis and Inflammatory Bowel Disease, Current Challenges, and Future Perspective

Journal of Crohn s and Colitis(2024)10.1093/ecco-jcc/jjae028

N/A

0DataRank · unranked

59 citations

Jeba Mercy Gnanasekaran, Devon L. Allison, Ling-Shiang Chuang, Xuesong He, Mario Aimetti +10 more

Colorectal Cancer in Inflammatory Bowel Disease: A Review of the Role of Gut Microbiota and Bacterial Biofilms in Disease Pathogenesis

Journal of Crohn s and Colitis(2024)10.1093/ecco-jcc/jjae061

N/A

0DataRank · unranked

24 citations

Cynthia L. Sears, Joanna Melia, David A. Muñiz Pedrogo

Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma

Clinical Microbiology and Infection(2024)10.1016/j.cmi.2024.01.013

N/A

0DataRank · unranked

19 citations

Hidetaka Kawamura, Kazuo Okadome, Satoko Ugai, Koichiro Haruki, Kota Arima +10 more

HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis

Journal of Clinical Investigation(2025)10.1172/jci184442

N/A

0DataRank · unranked

6 citations

Jung‐Hyun Kim, Iliana Herrera, Shaoguang Wu, Xinqun Wu, Seong‐Sik Park +15 more

Cynthia L. Sears

Indexed papers

Top data-sharing exemplar

Papers