Lei Zheng

Also affiliated with Johns Hopkins Medicine, Sidney Kimmel Cancer Center, Sidney Kimmel Comprehensive Cancer Center

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.459Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial

iScience(2024)10.1016/j.isci.2024.111569

Top 41%

0.459DataRank

Top 41%15 citations

Jacob T. Mitchell, Joseph A. Tandurella, Eric S. Christenson, Ludmila Danilova, Atul Deshpande +29 more

Papers

Driven by 41 papers — median percentile 59. Top paper: “Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism”.

Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00769-z

N/A

2.2DataRank · unranked

95 citations

Xingyi Pan, Kenji Fujiwara, Noelle R. Jurcak, Stephen Muth, Jiaojiao Zhou +6 more

A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma

Nature Communications(2023)10.1038/s41467-023-39196-9

N/A

1.4DataRank · unranked

87 citations

Carol Judkins, Keyu Li, Su Jin Lim, Jessica Hoare, Rose Parkinson +24 more

Neoantigen-based EpiGVAX vaccine initiates antitumor immunity in colorectal cancer

JCI Insight(2020)10.1172/jci.insight.136368

N/A

1.1DataRank · unranked

35 citations

Xingyi Pan, Kevin C. Soares, Nilofer S. Azad, Nita Ahuja, Christopher Gamper +6 more

Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial–Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma

Cancer Research(2024)10.1158/0008-5472.can-23-1660

N/A

0.867DataRank · unranked

44 citations

Benedict Kinny‐Köster, Joseph A. Tandurella, Jacob T. Mitchell, Dimitrios N. Sidiropoulos, Melanie Loth +29 more

Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy

Cancer Cell(2022)10.1016/j.ccell.2022.10.001

N/A

0.778DataRank · unranked

178 citations

Joseph A. Tandurella, Jessica Gai, Qingfeng Zhu, Su Jin Lim, Dwayne L. Thomas +26 more

Tumor Mutational Burden, Toxicity, and Response of Immune Checkpoint Inhibitors Targeting PD(L)1, CTLA-4, and Combination: A Meta-regression Analysis

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-0458

N/A

0.705DataRank · unranked

109 citations

Su Jin Lim, Aleksandra Popović, Nilofer S. Azad, Daniel A. Laheru, Lei Zheng +4 more

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-3841

N/A

0.704DataRank · unranked

108 citations

Samantha Guinn, Filippo Birocchi, Adam Kuo, Yi Sun, Rebecca C. Larson +34 more

Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-4165

N/A

0.677DataRank · unranked

90 citations

Jacquelyn W. Zimmerman, Reecha Suri, Haley Zlomke, Gabriel D. Ivey, Annamária Szabolcs +17 more

Vaccine-Induced Intratumoral Lymphoid Aggregates Correlate with Survival Following Treatment with a Neoadjuvant and Adjuvant Vaccine in Patients with Resectable Pancreatic Adenocarcinoma

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-2974

N/A

0.655DataRank · unranked

78 citations

Ding Ding, Barish H. Edil, Carol Judkins, Jennifer N. Durham, Dwayne L. Thomas +32 more

Dual Stromal Targeting Sensitizes Pancreatic Adenocarcinoma for Anti-Programmed Cell Death Protein 1 Therapy

Gastroenterology(2022)10.1053/j.gastro.2022.06.027

N/A

0.652DataRank · unranked

76 citations

Jianxin Wang, John Davelaar, Andrew Baker, Keyu Li, Nan Niu +17 more

Cancer-associated fibroblast heterogeneity is associated with organ-specific metastasis in pancreatic ductal adenocarcinoma

Journal of Hematology & Oncology(2021)10.1186/s13045-021-01203-1

N/A

0.612DataRank · unranked

58 citations

Jiaojiao Zhou, Qian Xiao, Kenji Fujiwara, Mengwen Zhang, Guanglan Mo +3 more

CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial

iScience(2024)10.1016/j.isci.2024.111569

Top 41%

0.459DataRank

Top 41%15 citations

Jacob T. Mitchell, Joseph A. Tandurella, Eric S. Christenson, Ludmila Danilova, Atul Deshpande +29 more

Inflammatory Signaling in Pancreatic Cancer Transfers Between a Single-cell RNA Sequencing Atlas and Co-Culture

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.14.500096

N/A

0.360DataRank · unranked

10 citations

Samantha Guinn, Joseph A. Tandurella, Jacob T. Mitchell, Dimitrios N. Sidiropoulos, Melanie Loth +24 more

Neoadjuvant and adjuvant antitumor vaccination alone or combination with PD1 blockade and CD137 agonism in patients with resectable pancreatic adenocarcinoma.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.4_suppl.558

N/A

0.345DataRank · unranked

9 citations

Carol Judkins, Su Jin Lim, Hao Wang, Rose Parkinson, Jessica Gai +15 more

Somatic loss of ATM is a late event in pancreatic tumorigenesis

The Journal of Pathology(2023)10.1002/path.6136

N/A

0.293DataRank · unranked

4 citations

Zhengdong Jiang, Danielle Hutchings, Valentyna Kryklyva, Christian Gauthier, Kohei Fujikura +18 more

Preliminary translational immune and stromal correlates in a randomized phase II trial of pembrolizumab with or without defactinib for resectable pancreatic ductal adenocarcinoma (PDAC).

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.4024

N/A

0.292DataRank · unranked

6 citations

John Davelaar, Jessica Gai, Zachariah Brown, Abrahm Levi, Sheila Linden +15 more

The impact of KRAS mutations on the clinical outcome and immune response following immunotherapy for pancreatic cancer

Annals of Pancreatic Cancer(2024)10.21037/apc-24-2

N/A

0.251DataRank · unranked

4 citations

Raymond Yu, Jessica Gai, Hao Wang, Ming Lei, Lei Zheng +1 more

In vivo bioluminescence tomography-guided system for pancreatic cancer radiotherapy research

Biomedical Optics Express(2024)10.1364/boe.523916

N/A

0.208DataRank · unranked

3 citations

Xiangkun Xu, Hamid Dehghani, Juvenal Reyes, Lei Zheng, Phuoc T. Tran +2 more

CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer

Gastroenterology(2023)10.1053/j.gastro.2023.06.037

N/A

0DataRank · unranked

25 citations

Juan Fu, MacKenzie Henderson, Fei Lee, Noelle R. Jurcak, Anja Henn +20 more

Engineered TCR T-cell therapy targeting mass spectrometry-identified natural epitope in PDAC

Cancer Letters(2023)10.1016/j.canlet.2023.216366

N/A

0DataRank · unranked

13 citations

Tengyi Zhang, Pan Li, Jessica Gai, Sophia Y. Chen, G. A. Espinoza +7 more

Reducing Ophthalmic Health Disparities Through Transfer Learning: A Novel Application to Overcome Data Inequality

Translational Vision Science & Technology(2023)10.1167/tvst.12.12.2

N/A

0DataRank · unranked

5 citations

Gadi Wollstein, Chisom T. Madu, Andrew Wronka, Lei Zheng, Ronald Zambrano +3 more

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity

Nature Biomedical Engineering(2023)10.1038/s41551-023-01131-0

N/A

0DataRank · unranked

108 citations

Jingyao Ma, Ruochen Shen, Jinghan Lin, Shuyi Li, Xiaoya Lu +25 more

Battling pancreatic cancer: the role of Chinese surgeons

Annals of Pancreatic Cancer(2022)10.21037/apc-2022-3

N/A

0DataRank · unranked

0 citations

Lei Zheng

Tumor- and Nerve-Derived Axon Guidance Molecule Promotes Pancreatic Ductal Adenocarcinoma Progression and Metastasis through Macrophage Reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.24.563862

N/A

0DataRank · unranked

3 citations

Vanessa Funes, Sanjana Davuluri, Hector E. Ibanez, Wei‐Chih Sun, Juan Fu +14 more

Data from Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response

(2023)10.1158/1078-0432.c.6532688

N/A

0DataRank · unranked

0 citations

Jacquelyn W. Zimmerman, Reecha Suri, Haley Zlomke, Gabriel D. Ivey, Annamária Szabolcs +17 more

Data from ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism

(2023)10.1158/1078-0432.c.6527265.v1

N/A

0DataRank · unranked

0 citations

Jingxuan Yang, Yuqing Zhang, Zhijun Zhou, Xiaobo Cui, Liyang Zhang +17 more

Data from Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response

(2023)10.1158/1078-0432.c.6532688.v1

N/A

0DataRank · unranked

0 citations

Jacquelyn W. Zimmerman, Reecha Suri, Haley Zlomke, Gabriel D. Ivey, Annamária Szabolcs +17 more

The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia

Cancer Cell(2024)10.1016/j.ccell.2024.03.009

N/A

0DataRank · unranked

142 citations

Yu Ren, Zhijun Zhou, Jingxuan Yang, Xiuhui Shi, Yang Cai +12 more

CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma

The Journal of Experimental Medicine(2022)10.1084/jem.20211631

N/A

0DataRank · unranked

65 citations

May Tun Saung, Keyu Li, Juan Fu, Kenji Fujiwara, Nan Niu +17 more

The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients

Nature Cancer(2024)10.1038/s43018-023-00697-7

N/A

0DataRank · unranked

87 citations

Ognjen Nikolic, Arkadiusz Gertych, Sarah J. Parker, Andrew Hendifar, Pranav Singh +9 more

Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses

Journal of Hematology & Oncology(2022)10.1186/s13045-022-01253-z

N/A

0DataRank · unranked

73 citations

Keyu Li, Nan Niu, Yingkuan Shao, Ding Ding, Dwayne L. Thomas +13 more

Overcome the challenge for intratumoral injection of STING agonist for pancreatic cancer by systemic administration

Journal of Hematology & Oncology(2024)10.1186/s13045-024-01576-z

N/A

0DataRank · unranked

20 citations

Junke Wang, Rui Zhang, Jiawei Zhou, Birginia Espinoza, Nan Niu +18 more

Giant obscurin regulates migration and metastasis via RhoA-dependent cytoskeletal remodeling in pancreatic cancer

Cancer Letters(2021)10.1016/j.canlet.2021.11.016

N/A

0DataRank · unranked

30 citations

Daniel J. Shea, Bin Sheng Wong, Talia Guardia, Se Jong Lee, Christopher L. Yankaskas +4 more

Spinal cord stimulation attenuates paclitaxel-induced gait impairment and mechanical hypersensitivity via peripheral neuroprotective mechanisms in tumor-bearing rats

Regional Anesthesia & Pain Medicine(2024)10.1136/rapm-2024-105433

N/A

0DataRank · unranked

9 citations

Kimberly Stephens, Karla R. Sanchez, Vivian N Liu, Lei Zheng, Vasudha Goel +3 more

Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2019-000351

N/A

0DataRank · unranked

38 citations

May Tun Saung, Hao Jing, Brian Herbst, MacKenzie Zarecki, Stephen Muth +13 more

Pancreatic ductal adenocarcinoma immune microenvironment and immunotherapy prospects

Chronic Diseases and Translational Medicine(2020)10.1016/j.cdtm.2020.01.002

N/A

0DataRank · unranked

70 citations

Jia‐Long Yuan, Diego Trafton, Jianxin Wang, Nan Niu, Chunhui Yuan +3 more

Comparison of Shared Class I HLA-Bound Noncanonical Neoepitopes between Normal and Neoplastic Tissues of Pancreatic Adenocarcinoma

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-2251

N/A

0DataRank · unranked

1 citations

Betul Celiker, Yingkuan Shao, Jessica Gai, C. Mark Hill, Chunyu Wang +2 more

Clinical development of immuno-oncology therapeutics

Cancer Letters(2025)10.1016/j.canlet.2025.217616

N/A

0DataRank · unranked

44 citations

Qi Chen, Qiang Shan, Tingbo Liang, Patrick M. Forde, Lei Zheng +1 more

Distinct response to IL-1β blockade in liver- and lung-specific metastasis mouse models of pancreatic cancer with heterogeneous tumor microenvironments

Experimental Hematology and Oncology(2025)10.1186/s40164-025-00607-w

N/A

0DataRank · unranked

7 citations

Heng‐Chung Kung, Birginia Espinoza, India Washington, Kai Chen, Kaiyi Mu +7 more

A nanoparticle platform for the co-delivery of multiple antigen epitope peptides and STING agonist to lymph nodes for cancer immunotherapy

International Journal of Pharmaceutics(2025)10.1016/j.ijpharm.2025.125757

N/A

0DataRank · unranked

3 citations

Brady A. Campbell, Xiaoya Lu, Betul Celiker, Lei Zheng, May Tun Saung +2 more

ASO Visual Abstract: Survival Outcomes and Genetic Characteristics of Resected Pancreatic Acinar Cell Carcinoma

Annals of Surgical Oncology(2025)10.1245/s10434-024-16439-7

N/A

0DataRank · unranked

0 citations

Shannon N. Radomski, Joanne F. Chou, Mengyuan Liu, Thomas Clark Howell, Wungki Park +18 more

Lei Zheng

Indexed papers

Top data-sharing exemplar

Papers