🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Zachary T. Schug

The Wistar Institute

ORCID: 0000-0003-4197-8227
Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile
1.8Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Racial disparities in triple negative breast cancer: toward a causal architecture approach

Breast Cancer Research(2022)10.1186/s13058-022-01533-z
Top 12%
1.8DataRank
Top 12%40 citations

Madeline M. Brooks, Shannon M. Lynch, Jennifer Sims‐Mourtada, Zachary T. Schug, Frank C. Curriero +1 more

Papers

Driven by 19 papers — median percentile 88. Top paper: “Racial disparities in triple negative breast cancer: toward a causal architecture approach”.

Racial disparities in triple negative breast cancer: toward a causal architecture approach

Breast Cancer Research(2022)10.1186/s13058-022-01533-z
Top 12%
1.8DataRank
Top 12%40 citations

Madeline M. Brooks, Shannon M. Lynch, Jennifer Sims‐Mourtada, Zachary T. Schug, Frank C. Curriero +1 more

Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+ uniporter

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101436
N/A
0.985DataRank · unranked
24 citations

Zachary T. Schug, David M. Booth, David I Yule, Katsuhiko Mikoshiba, György Hajnóczky +2 more

Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma

Nature Cancer(2021)10.1038/s43018-020-00160-x
N/A
0.725DataRank · unranked
125 citations

Takeshi Fukumoto, Jianhuang Lin, Timothy Nacarelli, Yemin Wang, Dionzie Ong +16 more

Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer

Nature Cancer(2023)10.1038/s43018-023-00636-6
N/A
0.719DataRank · unranked
120 citations

Seamus O’Connor, Katherine Pniewski, Toshitha Kannan, Reyes Acosta, Gauri Mirji +15 more

Targeting cancer metabolism in the era of precision oncology

Nature Reviews Drug Discovery(2021)10.1038/s41573-021-00339-6
N/A
0DataRank · unranked
1205 citations

Zachary T. Schug, Joseph M. Salvino, Chi V. Dang, Zachary E. Stine

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Cancer Research(2021)10.1158/0008-5472.can-20-1847
N/A
0DataRank · unranked
99 citations

Katherine Pniewski, Caroline Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco‐Silva +9 more

Metabolic Alterations and Therapeutic Opportunities in Rare Forms of Melanoma

Trends in cancer(2021)10.1016/j.trecan.2021.05.005
N/A
0DataRank · unranked
30 citations

Zachary T. Schug, Andrew E. Aplin, Anna Han

A Population Health Assessment in a Community Cancer Center Catchment Area: Triple-Negative Breast Cancer, Alcohol Use, and Obesity in New Castle County, Delaware

Cancer Epidemiology Biomarkers & Prevention(2021)10.1158/1055-9965.epi-21-1031
N/A
0DataRank · unranked
17 citations

Madeline M. Brooks, Jennifer Sims-Mourtada, Zachary T. Schug, Dawn J. Leonard, Nicholas J. Petrelli +2 more

Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2021)10.1038/s41388-021-01645-4
N/A
0DataRank · unranked
2 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

Racial Disparities in Triple Negative Breast Cancer: Toward a Causal Architecture Approach

Research Square(2021)10.21203/rs.3.rs-1177963/v1
N/A
0DataRank · unranked
2 citations

Madeline M. Brooks, Shannon M. Lynch, Jennifer Sims‐Mourtada, Zachary T. Schug, Frank C. Curriero +1 more

Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth

Cell Metabolism(2022)10.1016/j.cmet.2022.04.006
N/A
0DataRank · unranked
69 citations

Mariam Fokra, Alona Feldman, Boris Sarvin, Nikita Sarvin, Keren Nevo‐Dinur +6 more

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma

Oncogene(2022)10.1038/s41388-021-02154-0
N/A
0DataRank · unranked
16 citations

Vivian Chua, Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Emily Hunter +7 more

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth

Cancers(2023)10.3390/cancers15133451
N/A
0DataRank · unranked
10 citations

Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia +15 more

Data from Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

(2023)10.1158/0008-5472.c.6512743.v1
N/A
0DataRank · unranked
0 citations

Katherine Pniewski, Caroline E. Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco‐Silva +9 more

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0329
N/A
0DataRank · unranked
153 citations

Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera +17 more

ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

Cell Reports(2024)10.1016/j.celrep.2024.114988
N/A
0DataRank · unranked
25 citations

Kelsey Salcido, Katherine Pniewski, Dzmitry Mukha, Weili Ma, Toshitha Kannan +8 more

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

British Journal of Cancer(2020)10.1038/s41416-019-0711-3
N/A
0DataRank · unranked
86 citations

Caroline Perry, Adam Cohen‐Nowak, Katelyn D. Miller, Johan Vande Voorde, Qifeng Zhang +18 more

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2020)10.1038/s41388-020-01554-y
N/A
0DataRank · unranked
48 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

eLife(2020)10.7554/elife.55994
N/A
0DataRank · unranked
15 citations

Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V. Lee +10 more