Serge Gauthier

Montreal Neurological Institute and Hospital

Also affiliated with Douglas Mental Health University Institute, Texas Instruments (France), Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean, Alzheimer’s Disease Neuroimaging Initiative, Cognitive Neuroimaging Lab, Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal, McGill University

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.7Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer’s disease progression and heterogeneity

Science Advances(2022)10.1126/sciadv.abo6764

Top 13%

1.7DataRank

Top 13%98 citations

Quadri Adewale, Ahmed Faraz Khan, Simon Ducharme, Pedro Rosa‐Neto, Kieran J. O’Donnell +6 more

Papers

Driven by 59 papers — median percentile 87. Top paper: “Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease”.

Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease

Annals of Neurology(2022)10.1002/ana.26511

N/A

1.8DataRank · unranked

44 citations

Jorge J. Llibre‐Guerra, Yan Li, Austin McCullough, Carsten Hofmann, Jakub Wojtowicz +49 more

Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer’s disease progression and heterogeneity

Science Advances(2022)10.1126/sciadv.abo6764

Top 13%

1.7DataRank

Top 13%98 citations

Quadri Adewale, Ahmed Faraz Khan, Simon Ducharme, Pedro Rosa‐Neto, Kieran J. O’Donnell +6 more

Diagnosis of Alzheimer’s disease using plasma biomarkers adjusted to clinical probability

Nature Aging(2024)10.1038/s43587-024-00731-y

N/A

1.5DataRank · unranked

95 citations

Shorena Janelidze, Andréa Lessa Benedet, Nicholas J. Ashton, Javier Arranz Martínez, Armand González‐Escalante +51 more

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial

The Lancet Neurology(2025)10.1016/s1474-4422(25)00024-9

N/A

1.2DataRank · unranked

41 citations

Yan Li, Eric McDade, Jorge J. Llibre‐Guerra, David B. Clifford, Alireza Atri +62 more

Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease

JAMA Neurology(2024)10.1001/jamaneurol.2024.0991

N/A

1.0DataRank · unranked

29 citations

Haiyan Liu, Guoqiao Wang, Xinyu Shi, Tobias Bittner, Marzia A. Scelsi +94 more

A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease

Nature Medicine(2021)10.1038/s41591-021-01369-8

N/A

0.885DataRank · unranked

365 citations

Martin R. Farlow, Eric McDade, David B. Clifford, Guoqiao Wang, Jorge J. Llibre‐Guerra +61 more

Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease

Nature Medicine(2023)10.1038/s41591-023-02380-x

N/A

0.865DataRank · unranked

318 citations

Guilherme Povala, Pâmela C.L. Ferreira, João Pedro Ferrari‐Souza, Douglas Teixeira Leffa, Firoza Z Lussier +28 more

Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity

JAMA(2025)10.1001/jama.2025.7817

N/A

0.846DataRank · unranked

52 citations

Fiona Heeman, Sheelakumari Raghavan, Alejandro Costoya‐Sánchez, Martijn van Essen, Ismini Mainta +95 more

Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease

European Journal of Nuclear Medicine and Molecular Imaging(2023)10.1007/s00259-023-06209-0

N/A

0.765DataRank · unranked

24 citations

Austin McCullough, Brian A. Gordon, Nelly Joseph‐Mathurin, Shaney Flores, Nicole S. McKay +48 more

The neurophysiological brain-fingerprint of Parkinson’s disease

EBioMedicine(2024)10.1016/j.ebiom.2024.105201

N/A

0.760DataRank · unranked

27 citations

Alex I. Wiesman, Justine Y Hansen, Bratislav Misic, Sylvain Baillet, John Breitner +94 more

Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease

Molecular Psychiatry(2022)10.1038/s41380-022-01716-2

N/A

0.752DataRank · unranked

149 citations

Pâmela C.L. Ferreira, Bruna Bellaver, Cécile Tissot, Yi-Ting Wang, Douglas Teixeira Leffa +28 more

Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer’s disease

Brain(2020)10.1093/brain/awaa342

N/A

0.718DataRank · unranked

119 citations

Antoine Leuzy, Tharick A. Pascoal, Nicholas J. Ashton, Sulantha Mathotaarachchi, Mélissa Savard +12 more

APOEε4 potentiates the relationship between amyloid-β and tau pathologies

Molecular Psychiatry(2020)10.1038/s41380-020-0688-6

N/A

0.705DataRank · unranked

109 citations

Andréa Lessa Benedet, Tharick A. Pascoal, Sulantha Mathotaarachchi, Mélissa Savard, Mira Chamoun +13 more

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Nature Communications(2021)10.1038/s41467-021-25492-9

N/A

0.698DataRank · unranked

104 citations

Alex T. Baria, Alexa Pichet Binette, Brian A. Gordon, Jasmeer P. Chhatwal, Carlos Cruchaga +94 more

Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer’s disease

Molecular Psychiatry(2020)10.1038/s41380-020-0818-1

N/A

0.593DataRank · unranked

51 citations

Arturo Aliaga, Monica Shin, Sulantha Mathotaarachchi, Andréa Lessa Benedet, Tharick A. Pascoal +16 more

Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical Research

Neurology(2024)10.1212/wnl.0000000000209753

N/A

0.510DataRank · unranked

29 citations

Wagner S. Brum, Wyllians Vendramini Borelli, Joseph Therriault, Marco Antônio De Bastiani, Amanda Gressler Moreira +17 more

Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials

Neurology(2023)10.1212/wnl.0000000000207115

N/A

0.505DataRank · unranked

28 citations

João Pedro Ferrari‐Souza, Cécile Tissot, Bruna Bellaver, Douglas Teixeira Leffa, Firoza Z Lussier +19 more

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease

Nature Neuroscience(2025)10.1038/s41593-025-02103-0

N/A

0.494DataRank · unranked

26 citations

Guilherme Povala, Nesrine Rahmouni, Bruna Bellaver, Pâmela C.L. Ferreira, Marco Antônio De Bastiani +27 more

Identification of late-stage tau accumulation using plasma phospho-tau217

EBioMedicine(2024)10.1016/j.ebiom.2024.105413

N/A

0.483DataRank · unranked

24 citations

Joseph Therriault, Erin M. Jonaitis, Rachael E. Wilson, Rebecca E. Langhough, Nesrine Rahmouni +27 more

Plasma levels of phosphorylated tau 181 are associated with cerebral metabolic dysfunction in cognitively impaired and amyloid-positive individuals

Brain Communications(2021)10.1093/braincomms/fcab073

N/A

0.477DataRank · unranked

23 citations

Andréa L. Benedet, Joseph Therriault, Tharick A. Pascoal, Cécile Tissot, Mira Chamoun +16 more

Impact of long- and short-range fibre depletion on the cognitive deficits of fronto-temporal dementia

eLife(2022)10.7554/elife.73510

N/A

0.416DataRank · unranked

15 citations

Tharick A Pascoal, Stijn Servaes, Thijs Dhollander, Yasser Iturria‐Medina, Min Su Kang +8 more

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial

medRxiv(2024)10.1101/2024.10.29.24316289

N/A

0.351DataRank · unranked

6 citations

Yan Li, Eric McDade, Jorge J. Llibre‐Guerra, David B. Clifford, Alireza Atri +63 more

Functional brain age prediction suggests accelerated aging in preclinical familial Alzheimer’s disease, irrespective of fibrillar amyloid-beta pathology

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.06.076745

N/A

0.292DataRank · unranked

6 citations

Alex T. Baria, Alexa Pichet Binette, Brian A. Gordon, Jasmeer P. Chhatwal, Carlos Cruchaga +15 more

Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease

Acta Neuropathologica(2025)10.1007/s00401-025-02890-7

N/A

0.292DataRank · unranked

6 citations

Erin Franklin, Yan Li, Nelly Joseph‐Mathurin, Aime Burns, Diana A. Hobbs +93 more

Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials

The Journal of Prevention of Alzheimer s Disease(2024)10.14283/jpad.2024.61

N/A

0.283DataRank · unranked

4 citations

Jonathan Li, Ellen Ziegemeier, Sarah F. Adams, Eric McDade, David B. Clifford +34 more

Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer’s Disease: Synthesis of Evidence from Observational and Interventional Trials

CNS Drugs(2026)10.1007/s40263-025-01251-y

N/A

0.208DataRank · unranked

3 citations

P. Murali Doraiswamy, John A. Hey, Duygu Tosun, Frederik Barkhof, Jerome Barakos +24 more

Interactive rather than independent effect of APOE and sex potentiates tau deposition in women

Figshare(2023)10.32920/24438049.v1

N/A

0.208DataRank · unranked

3 citations

Tharick A. Pascoal, Joseph Therriault, Min-Su Kang, Andréa Lessa Benedet, Mélissa Savard +8 more

Potential utility of plasma p-tau and NfL as surrogate biomarkers for preventive clinical trials

medRxiv(2022)10.1101/2022.08.17.22278853

N/A

0.104DataRank · unranked

1 citations

João Pedro Ferrari‐Souza, Cécile Tissot, Bruna Bellaver, Douglas Teixeira Leffa, Firoza Z Lussier +19 more

Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer’s disease pathology

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2502674122

N/A

0DataRank · unranked

4 citations

Christine Tardif, Ilana R. Leppert, Giulia Baracchini, Colleen Hughes, Jennifer Tremblay‐Mercier +37 more

Drug repurposing for Alzheimer’s disease: a Delphi consensus and stakeholder consultation

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01895-4

N/A

0DataRank · unranked

3 citations

Janet Sultana, Kate Stych, Roger Mills, Jeff Cummings, Gareth Williams +16 more

Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN‐TU‐001 trial

Alzheimer s & Dementia(2025)10.1002/alz.70347

N/A

0DataRank · unranked

4 citations

Charles D. Chen, Brian A. Gordon, Nelly Joseph‐Mathurin, Clifford R. Jack, Robert Koeppe +47 more

Optimized atlas for early tau-PET staging via native space segmentations

Neurobiology of Aging(2025)10.1016/j.neurobiolaging.2025.11.002

N/A

0DataRank · unranked

5 citations

Brandon J. Hall, Tevy Chan, Lydia Trudel, Gleb Bezgin, Seyyed Ali Hosseini +14 more

Agitation and impulsivity in mid and late life as possible risk markers for incident dementia

Alzheimer s & Dementia Translational Research & Clinical Interventions(2020)10.1002/trc2.12016

N/A

0DataRank · unranked

42 citations

Sascha Gill, Sophie Hu, Erin D. Foster, Myuri Ruthirakuhan, Allis F. Sellek +13 more

Non-Amyloid Approaches to Disease Modification for Alzheimer's Disease: An EU/US CTAD Task Force Report

The Journal of Prevention of Alzheimer s Disease(2020)10.14283/jpad.2020.18

N/A

0DataRank · unranked

25 citations

Paul Aisen, Jeffrey L. Cummings, Michael J. Detke, Frank M. Longo, Rema Raman +8 more

Impact of long- and short-range fiber depletion on the cognitive deficits of fronto-temporal dementia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.01.064576

N/A

0DataRank · unranked

2 citations

Tharick A. Pascoal, Thijs Dhollander, Yasser Iturria‐Medina, Paolo Vitali, Joseph Therriault +6 more

Plasma Levels of Phosphorylated Tau 181 Are Associated With Cerebral Metabolic Dysfunction in Cognitively Impaired Individuals

Research Square(2020)10.21203/rs.3.rs-69968/v1

N/A

0DataRank · unranked

2 citations

Andréa L. Benedet, Joseph Therriault, Tharick A. Pascoal, Cécile Tissot, Mira Chamoun +15 more

Differential early subcortical involvement in genetic FTD within the GENFI cohort

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102646

N/A

0DataRank · unranked

66 citations

Emily Todd, Georgia Peakman, David M. Cash, Rhian S. Convery, Lucy L. Russell +95 more

Biomarker modeling of Alzheimer’s disease using PET-based Braak staging

Nature Aging(2022)10.1038/s43587-022-00204-0

N/A

0DataRank · unranked

309 citations

Tharick A. Pascoal, Firoza Z Lussier, Cécile Tissot, Mira Chamoun, Gleb Bezgin +17 more

[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease

Nature Communications(2022)10.1038/s41467-022-30653-5

N/A

0DataRank · unranked

40 citations

Mira Chamoun, Elad Lax, Hsiao‐Ying Wey, Monica Shin, Kok Pin Ng +32 more

The Association of Age-Related and Off-Target Retention with Longitudinal Quantification of [ 18 F]MK6240 Tau PET in Target Regions

Journal of Nuclear Medicine(2022)10.2967/jnumed.122.264434

N/A

0DataRank · unranked

27 citations

Stijn Servaes, Firoza Z Lussier, João Pedro Ferrari‐Souza, Joseph Therriault, Pâmela C.L. Ferreira +27 more

A Neuropsychological Perspective on Defining Cognitive Impairment in the Clinical Study of Alzheimer’s Disease: Towards a More Continuous Approach

Journal of Alzheimer s Disease(2022)10.3233/jad-215098

N/A

0DataRank · unranked

30 citations

Louisa Thompson, Sietske A.M. Sikkes, Paul Maruff, José Luis Molinuevo, Henrik Zetterberg +8 more

Therapeutic Targets for Alzheimer's Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report

The Journal of Prevention of Alzheimer s Disease(2022)10.14283/jpad.2022.29

N/A

0DataRank · unranked

13 citations

Adam L. Boxer, D. S. Knopman, Jonathan T. Sims, Rachelle S. Doody, P. Aisen +4 more

Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer’s disease

Brain Communications(2022)10.1093/braincomms/fcac085

N/A

0DataRank · unranked

13 citations

Jacob W Vogel, Thomas Funck, Vladimir Hachinski, Serge Gauthier, Jonathan Vöglein +8 more

Stage-dependent differential influence of metabolic and structural networks on memory across Alzheimer’s disease continuum

eLife(2022)10.7554/elife.77745

N/A

0DataRank · unranked

4 citations

Xing Qian, Kwun Kei Ng, Fang Ji, Pedro Rosa‐Neto, Serge Gauthier +4 more

Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease

medRxiv(2022)10.1101/2022.01.25.22269841

N/A

0DataRank · unranked

6 citations

Pâmela C.L. Ferreira, Bruna Bellaver, Cécile Tissot, Yi-Ting Wang, Douglas Teixeira Leffa +28 more

Stage dependent differential influence of metabolic and structural networks on memory across Alzheimer’s disease continuum

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.28.482280

N/A

0DataRank · unranked

1 citations

Xing Qian, Kwun Kei Ng, Fang Ji, Pedro Rosa‐Neto, Serge Gauthier +4 more

Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease

Alzheimer s & Dementia(2023)10.1002/alz.13026

N/A

0DataRank · unranked

161 citations

Stijn Servaes, Cécile Tissot, Nesrine Rahmouni, Nicholas J. Ashton, Andréa Lessa Benedet +23 more

APOE ε4 associates with microglial activation independently of Aβ plaques and tau tangles

Science Advances(2023)10.1126/sciadv.ade1474

N/A

0DataRank · unranked

80 citations

Firoza Z Lussier, Douglas Teixeira Leffa, Joseph Therriault, Cécile Tissot, Bruna Bellaver +31 more

Plasma p‐tau231 and p‐tau217 inform on tau tangles aggregation in cognitively impaired individuals

Alzheimer s & Dementia(2023)10.1002/alz.13393

N/A

0DataRank · unranked

52 citations

Joseph Therriault, Cécile Tissot, João Pedro Ferrari‐Souza, Andréa Lessa Benedet, Guilherme Povala +27 more

APOEε4 potentiates amyloid β effects on longitudinal tau pathology

Nature Aging(2023)10.1038/s43587-023-00490-2

N/A

0DataRank · unranked

41 citations

Bruna Bellaver, Pâmela C.L. Ferreira, Andréa Lessa Benedet, Guilherme Povala, Firoza Z Lussier +34 more

Health System Change for Alzheimer’s Disease-Modifying Therapies in Canada: Beginning the Discussion

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques(2023)10.1017/cjn.2023.322

N/A

0DataRank · unranked

8 citations

Zahinoor Ismail, Melanie Wilson, Serge Gauthier, Louis Verret, Ging‐Yuek Robin Hsiung +2 more

Dynamic Amyloid and Metabolic Signatures of Delayed Recall Performance within the Clinical Spectrum of Alzheimer’s Disease

Brain Sciences(2023)10.3390/brainsci13020232

N/A

0DataRank · unranked

2 citations

Tharick A. Pascoal, Joseph Therriault, Jared Rowley, Sara Mohaddes, Monica Shin +7 more

Interactive rather than independent effect of APOE and sex potentiates tau deposition in women

(2023)10.32920/24438049

N/A

0DataRank · unranked

0 citations

Tharick A. Pascoal, Joseph Therriault, Min-Su Kang, Andréa Lessa Benedet, Mélissa Savard +8 more

Hormone therapy is associated with lower Alzheimer’s disease tau biomarkers in post-menopausal females -evidence from two independent cohorts

Alzheimer s Research & Therapy(2024)10.1186/s13195-024-01509-5

N/A

0DataRank · unranked

19 citations

Joseph Therriault, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur C. Macedo +12 more

Neurobehavioral Mechanisms Influencing the Association Between Generativity, the Desire to Promote Well-Being of Younger Generations, and Purpose in Life in Older Adults at Risk for Alzheimer’s Disease

The Journals of Gerontology Series B(2024)10.1093/geronb/gbae060

N/A

0DataRank · unranked

6 citations

Linda Li, Giulia Baracchini, Jennifer Tremblay‐Mercier, R. Nathan Spreng, Paul Aisen +93 more

Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease

European Journal of Neurology(2024)10.1111/ene.16255

N/A

0DataRank · unranked

8 citations

Joseph Therriault, Antonio Aliaga, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni +21 more

Remote cognitive and behavioral assessment: Report of the Alzheimer Society of Canada Task Force on dementia care best practices for COVID‐19

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12111

N/A

0DataRank · unranked

135 citations

Megan E. O’Connell, John D. Fisk, Serge Gauthier, Richard Camicioli, Zahinoor Ismail +2 more

Uncovering atrophy progression pattern and mechanisms in individuals at risk of Alzheimer's disease

Brain Communications(2025)10.1093/braincomms/fcaf099

N/A

0DataRank · unranked

4 citations

Shady Rahayel, Alexandre Pastor‐Bernier, Frédéric St‐Onge, Andrew Vo, François Rheault +93 more

Tau profiling across Alzheimer’s disease staging reveals vulnerability to disease pathophysiology

European Journal of Nuclear Medicine and Molecular Imaging(2025)10.1007/s00259-025-07257-4

N/A

0DataRank · unranked

4 citations

Tharick A. Pascoal, Joseph Therriault, Firoza Z Lussier, Stijn Servaes, Min Su Kang +30 more

Serge Gauthier

Indexed papers

Top data-sharing exemplar

Papers