Lars Plate

Also affiliated with Vanderbilt University Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 35 papers. Top paper: “Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming”.

Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming

Nature Chemical Biology(2020)10.1038/s41589-020-0584-z

N/A

0.784DataRank · unranked

185 citations

Aparajita Madhavan, Lauren Čech, Bryan O. Seguinot, Ryan J Paxman, Emery Smith +8 more

Benchmarking AlphaFold2 on peptide structure prediction

Structure(2022)10.1016/j.str.2022.11.012

N/A

0.749DataRank · unranked

146 citations

Taylor Jones, Lars Plate, Jens Meiler, Alican Gulsevin, Eli Fritz McDonald

Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing

ACS Chemical Biology(2019)10.1021/acschembio.9b00134

N/A

0.672DataRank · unranked

87 citations

Lars Plate, Richard I. Morimoto, Michael J. Bollong, Evan T. Powers, R. Luke Wiseman +1 more

Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants

PLoS ONE(2024)10.1371/journal.pone.0297560

N/A

0.538DataRank · unranked

35 citations

Kathryn E. Oliver, Jonathan P. Schlebach, Jens Meiler, Lars Plate, Eli Fritz McDonald

General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants

Cell chemical biology(2023)10.1016/j.chembiol.2023.05.001

N/A

0.524DataRank · unranked

32 citations

Eli Fritz McDonald, Wesley D. Penn, Charles P. Kuntz, Karen Noguera, Laura M. Chamness +6 more

BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2305092120

N/A

0.509DataRank · unranked

12 citations

Samantha H. Schaffner, Jonathan P. Davies, Mary Lauren Benton, Lars Plate, Jared T. Nordman +1 more

Structural Comparative Modeling of Multi-Domain F508del CFTR

Biomolecules(2022)10.3390/biom12030471

N/A

0.470DataRank · unranked

22 citations

Hope Woods, Shannon T. Smith, Min‐Soo Kim, Clara T. Schoeder, Lars Plate +2 more

Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation using Targeted RNA-sequencing

10.1101/499046

N/A

0.171DataRank · unranked

2 citations

Lars Plate, Richard I. Morimoto, Michael J. Bollong, Evan T. Powers, R. Luke Wiseman +1 more

Cystic Fibrosis Modulator Therapies: Bridging Insights from CF to other Membrane Protein Misfolding Diseases

Israel Journal of Chemistry(2024)10.1002/ijch.202300152

N/A

0.165DataRank · unranked

2 citations

Lars Plate, Minsoo Kim

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegeneration

Molecular Therapy(2021)10.1016/j.ymthe.2021.01.033

N/A

0DataRank · unranked

42 citations

Denisse Sepúlveda, Paulina Troncoso-Escudero, Paula García-Huerta, Constanza González, Lars Plate +17 more

Control of mammalian brain ageing by the unfolded protein response transcription factor XBP1

Research Square(2020)10.21203/rs.3.rs-83658/v1

N/A

0DataRank · unranked

0 citations

Giovanni Tamburini, Gabriela Martínez, Danilo B. Medinas, Yannis Gerakis, Tim Miedema +19 more

Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging

The EMBO Journal(2022)10.15252/embj.2022111952

N/A

0DataRank · unranked

78 citations

Giovanni Tamburini, Gabriela Martínez, Álvaro O. Ardiles, Danilo B. Medinas, Yannis Gerakis +24 more

Glycosylation Limits Forward Trafficking of the Tetraspan Membrane Protein PMP22

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.18.423452

N/A

0DataRank · unranked

0 citations

Madison T. Wright, Darren R. Heintzman, Lars Plate, Charles R. Sanders, Justin T. Marinko

Identification of replication fork-associated proteins in Drosophila embryos and cultured cells using iPOND coupled to quantitative mass spectrometry

Scientific Reports(2022)10.1038/s41598-022-10821-9

N/A

0DataRank · unranked

9 citations

Madison T. Wright, Dongsheng Han, Reyhaneh Tirgar, Lars Plate, Jared T. Nordman +1 more

Compendium of proteins containing segments that exhibit zero‐tolerance to amino acid variation in humans

Protein Science(2022)10.1002/pro.4408

N/A

0DataRank · unranked

2 citations

Jake N Hermanson, David C. Samuels, Lars Plate, Charles R. Sanders, Adam L. Sanders

Time-Resolved Interactome Profiling Deconvolutes Secretory Protein Quality Control Dynamics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.04.506558

N/A

0DataRank · unranked

8 citations

Bibek Timalsina, Valeria García López, Jake Hermanson, Sarah Garcia, Lars Plate +1 more

Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.14.512300

N/A

0DataRank · unranked

3 citations

Eli Fritz McDonald, Wesley D. Penn, Charles P. Kuntz, Karen Noguera, Laura M. Chamness +6 more

The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.16.508322

N/A

0DataRank · unranked

2 citations

Jonathan P. Davies, Lars Plate, Jared T. Nordman, Reyhaneh Tirgar

Identification of replication fork-associated proteins in Drosophila embryos and cultured cells using iPOND coupled to quantitative mass spectrometry

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.18.476773

N/A

0DataRank · unranked

0 citations

Madison T. Wright, Dongsheng Han, Reyhaneh Tirgar, Lars Plate, Jared T. Nordman +1 more

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.17.387480

N/A

0DataRank · unranked

1 citations

Denisse Sepúlveda, Paulina Troncoso-Escudero, Paula García-Huerta, Constanza González, Lars Plate +16 more

Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.119164

N/A

0DataRank · unranked

4 citations

Paulina Troncoso-Escudero, Di Wu, Arun Thiruvalluvan, Marisol Cisternas, Daniel R. Henríquez +21 more

The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo

PLoS Genetics(2023)10.1371/journal.pgen.1010682

N/A

0DataRank · unranked

10 citations

Jonathan P. Davies, Lars Plate, Jared T. Nordman, Reyhaneh Tirgar

Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.04.527134

N/A

0DataRank · unranked

8 citations

Eli Fritz McDonald, Carleen Mae P. Sabusap, Bibek Timalsina, Disha Joshi, Jeong S. Hong +4 more

Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.05.561147

N/A

0DataRank · unranked

8 citations

Kathryn E. Oliver, Jonathan P. Schlebach, Jens Meiler, Lars Plate, Eli Fritz McDonald

BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.28.534572

N/A

0DataRank · unranked

1 citations

Samantha H. Schaffner, Jonathan P. Davies, Mary Lauren Benton, Lars Plate, Jared T. Nordman +1 more

Site-Specific Crosslinking Reveals Phosphofructokinase-L Inhibition Drives Self-Assembly and Attenuation of Protein Interactions

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.19.558525

N/A

0DataRank · unranked

0 citations

Eli Fritz McDonald, Sydney O. Shuster, Caitlin M. Davis, Lars Plate, Athira Sivadas

Control of mammalian brain aging by the unfolded protein response (UPR)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.13.039172

N/A

0DataRank · unranked

17 citations

Giovani Tamburini, Gabriela Martínez, Danilo B. Medinas, Yannis Gerakis, Tim Miedema +19 more

The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel KV11.1 associated with long QT syndrome

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107465

N/A

0DataRank · unranked

5 citations

Lea A. Barny, Tri Q., Eli Fritz McDonald, Björn C. Knollmann, Lars Plate +1 more

The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.31.574410

N/A

0DataRank · unranked

0 citations

Lea A. Barny, Tri Q., Eli Fritz McDonald, Lars Plate, Björn C. Knollmann +1 more

Recent developments in cystic fibrosis drug discovery: where are we today?

Expert Opinion on Drug Discovery(2025)10.1080/17460441.2025.2490250

N/A

0DataRank · unranked

5 citations

Ashlyn G. Winters, JaNise J Jackson, John A. Olson, Min‐Soo Kim, Kaitlyn V. Ledwitch +7 more

General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR Variants

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.03.647093

N/A

0DataRank · unranked

0 citations

John A. Olson, Minsoo Kim, Catherine Foye, JaNise Jackson, Eli Fritz McDonald +8 more

General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants

eLife(2025)10.7554/elife.107180

N/A

0DataRank · unranked

0 citations

John A. Olson, Minsoo Kim, Catherine Foye, JaNise J Jackson, Eli Fritz McDonald +8 more

Revealing functional insights into ER proteostasis through proteomics and interactomics

Experimental Cell Research(2020)10.1016/j.yexcr.2020.112417

N/A

0DataRank · unranked

12 citations

Lars Plate, Madison T. Wright

Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100719

N/A

0DataRank · unranked

28 citations

Madison T. Wright, Jonathan P. Schlebach, Katherine R. Clowes, Darren R. Heintzman, Lars Plate +2 more

Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

Acta Neuropathologica(2020)10.1007/s00401-020-02183-1

N/A

0DataRank · unranked

72 citations

Paulina Troncoso-Escudero, Di Wu, Arun Thiruvalluvan, Marisol Cisternas-Olmedo, Daniel R. Henríquez +22 more