Lingyin Li

Also affiliated with Palo Alto Institute, Stanford University

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP”.

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP

Molecular Cell(2020)10.1016/j.molcel.2020.10.021

N/A

0.789DataRank · unranked

191 citations

Rachel E. Mardjuki, Xianlan Wen, Gaelen T. Hess, Christopher Ritchie, Jacqueline A. Carozza +5 more

ENPP1 is an innate immune checkpoint of the anticancer cGAMP–STING pathway in breast cancer

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2313693120

N/A

0.646DataRank · unranked

73 citations

Volker Böhnert, Alby J. Joseph, Valentino Sudaryo, Gemini Skariah, Jason Swinderman +9 more

Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

Molecular Cell(2023)10.1016/j.molcel.2023.11.026

N/A

0.596DataRank · unranked

52 citations

Yu Xiao, Erin Huiting, Xujun Cao, Dong Li, Jie Ren +8 more

Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint

Cell Reports(2024)10.1016/j.celrep.2024.114209

N/A

0.550DataRank · unranked

38 citations

Songnan Wang, Jacqueline A. Carozza, Bahar Zirak, Vishvak Subramanyam, Gita C. Abhiraman +4 more

Discovery of VH domains that allosterically inhibit ENPP1

Nature Chemical Biology(2023)10.1038/s41589-023-01368-5

N/A

0.477DataRank · unranked

23 citations

Colton J. Bracken, Jacqueline A. Carozza, Haoqing Wang, Elizabeth P. Young, Alon Wellner +5 more

Cysteine allostery and autoinhibition govern human STING oligomer functionality

Nature Chemical Biology(2025)10.1038/s41589-025-01951-y

N/A

0.406DataRank · unranked

14 citations

Xujun Cao, Sabrina L. Ergun, Evert Njomen, Stephen R. Lynch, Christopher Ritchie +3 more

Probing pathophysiology of extracellular cGAMP with substrate-selective ENPP1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.04.442665

N/A

0.165DataRank · unranked

2 citations

Anthony F. Cordova, Yasmeen AlSaif, Volker Böhnert, Gemini Skariah, Lingyin Li +1 more

Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway

Annual Review of Biochemistry(2022)10.1146/annurev-biochem-040320-101629

N/A

0DataRank · unranked

122 citations

Jacqueline A. Carozza, Lingyin Li, Christopher Ritchie

ENPP1’s regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2119189119

N/A

0DataRank · unranked

105 citations

Anthony F. Cordova, Jenifer A. Brown, Yasmeen AlSaif, Volker Böhnert, Xujun Cao +5 more

Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment

Cancer Research(2023)10.1158/0008-5472.can-23-0046

N/A

0DataRank · unranked

46 citations

Vignesh Viswanathan, Hongbin Cao, Weiruo Zhang, Li Guan, Manish Chamoli +11 more

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.01.543353

N/A

0DataRank · unranked

10 citations

Volker Böhnert, Alby J. Joseph, Valentino Sudaryo, Jason Swinderman, Feiqiao B. Yu +7 more

Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.01.543220

N/A

0DataRank · unranked

7 citations

Yu Xiao, Erin Huiting, Xujun Cao, Dong Li, Jie Ren +6 more

STING activation of IRF3 is tuned by PELI2 to suppress basal activation and reinforce the anti-viral response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.15.537029

N/A

0DataRank · unranked

3 citations

Lingyin Li, Christopher Ritchie

PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection

Molecular Cell(2024)10.1016/j.molcel.2024.06.001

N/A

0DataRank · unranked

12 citations

Lingyin Li, Christopher Ritchie

A cGAMP‐Containing Hydrogel for Prolonged SARS‐CoV‐2 Receptor‐Binding Domain Subunit Vaccine Exposure Induces a Broad and Potent Humoral Response

Advanced NanoBiomed Research(2024)10.1002/anbr.202400077

N/A

0DataRank · unranked

5 citations

Emily C. Gale, Lauren J. Lahey, Jerry Yan, Abigail E. Powell, Ben S. Ou +4 more

Identification of extracellular membrane protein ENPP3 as a major cGAMP hydrolase, cementing cGAMP’s role as an immunotransmitter

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.12.575449

N/A

0DataRank · unranked

10 citations

Songnan Wang, Jacqueline A. Carozza, Gita C. Abhiraman, Xuchao Lyu, Lingyin Li +1 more

Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.21.614248

N/A

0DataRank · unranked

3 citations

Dayanne R. Carvalho, J. Michelle Lee, Jacqueline A. Carozza, Xujun Cao, Anthony F. Cordova +2 more

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102336

N/A

0DataRank · unranked

5 citations

Randolph M. Johnson, Jacqueline A. Carozza, Daniel Fernández, Jan Scicinski, Neil A. Verity +7 more

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.18.654655

N/A

0DataRank · unranked

1 citations

Songnan Wang, Jacqueline A. Carozza, Daniel Fernández, Jan Scicinski, Neil A. Verity +6 more

Extracellular cGAMP is a cancer-cell-produced immunotransmitter involved in radiation-induced anticancer immunity

Nature Cancer(2020)10.1038/s43018-020-0028-4

N/A

0DataRank · unranked

338 citations

Volker Böhnert, Khanh Cong Nguyen, Gemini Skariah, Kelsey E. Shaw, Jenifer A. Brown +7 more

Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP

Cell chemical biology(2020)10.1016/j.chembiol.2020.07.007

N/A

0DataRank · unranked

109 citations

Jenifer A. Brown, Volker Böhnert, Daniel Fernández, Yasmeen AlSaif, Rachel E. Mardjuki +3 more

The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.13.948273

N/A

0DataRank · unranked

11 citations

Xianlan Wen, Rachel E. Mardjuki, Volker Böhnert, Gaelen T. Hess, Christopher Ritchie +5 more

Structure-aided development of small molecule inhibitors of ENPP1, the extracellular phosphodiesterase of the immunotransmitter cGAMP

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.30.125534

N/A

0DataRank · unranked

7 citations

Jenifer A. Brown, Volker Böhnert, Daniel Fernández, Yasmeen AlSaif, Rachel E. Mardjuki +3 more

Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes

ACS Central Science(2021)10.1021/acscentsci.1c00440

N/A

0DataRank · unranked

147 citations

Christopher Ritchie, Volker Böhnert, Lingyin Li, Anthony F. Cordova

Therapeutic Interventions Targeting Innate Immune Receptors: A Balancing Act

Chemical Reviews(2021)10.1021/acs.chemrev.1c00716

N/A

0DataRank · unranked

23 citations

Anthony F. Cordova, Lingyin Li, Xujun Cao