Alexandre Reuben

The University of Texas MD Anderson Cancer Center

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Supplemental Tables from Expansion of Candidate HPV-Specific T Cells in the Tumor Microenvironment during Chemoradiotherapy Is Prognostic in HPV16+ Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/2326-6066.22544087.v1

Top 100%

0DataRank

Top 100%0 citations

Molly B. El, Erica J. Lynn, Julianna Bronk, Tatiana V. Karpinets, Xiaogang Wu +40 more

Papers

Driven by 48 papers — median percentile 0. Top paper: “Identification of bacteria-derived HLA-bound peptides in melanoma”.

Identification of bacteria-derived HLA-bound peptides in melanoma

Nature(2021)10.1038/s41586-021-03368-8

N/A

7.4DataRank · unranked

444 citations

Adi Nagler, Deborah Nejman, Michal Alon, Chaya Barbolin, Eilon Barnea +48 more

Programmed Death-Ligand 1 Heterogeneity and Its Impact on Benefit From Immune Checkpoint Inhibitors in NSCLC

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.04.026

N/A

6.8DataRank · unranked

195 citations

Marcelo V. Negrão, Seyedeh Dibaj, Runzhe Chen, Alexandre Reuben, Jadi M. Bohac +32 more

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

Science(2018)10.1126/science.aan4236

N/A

1.3DataRank · unranked

4585 citations

C. N. Spencer, Luigi Nezi, Alexandre Reuben, Miles C. Andrews, Tatiana V. Karpinets +89 more

B cells and tertiary lymphoid structures promote immunotherapy response

Nature(2020)10.1038/s41586-019-1922-8

N/A

1.2DataRank · unranked

2719 citations

Sangeetha M. Reddy, Jianjun Gao, Shaojun Zhang, Rafet Başar, Rohit Thakur +55 more

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

Cancer Discovery(2016)10.1158/2159-8290.cd-15-1545

N/A

1.0DataRank · unranked

1012 citations

Whijae Roh, Alexandre Reuben, Zachary A. Cooper, Christine N. Spencer, Peter A. Prieto +39 more

Immunogenomic profiling of lung adenocarcinoma reveals poorly differentiated tumors are associated with an immunogenic tumor microenvironment

Lung Cancer(2022)10.1016/j.lungcan.2022.08.007

N/A

0.935DataRank · unranked

23 citations

Jiexin Zhang, Erin M. Bayley, Meredith Frank, Shin‐Heng Chiou, Carmen Behrens +21 more

Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance

Nature Medicine(2023)10.1038/s41591-023-02371-y

N/A

0.933DataRank · unranked

501 citations

Enyu Dai, Yating Li, Guangchun Han, Guangsheng Pei, Davis R. Ingram +39 more

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Nature Medicine(2021)10.1038/s41591-021-01406-6

N/A

0.910DataRank · unranked

429 citations

Connie P. M. Duong, Vancheswaran Gopalakrishnan, Valerio Iebba, W. S. Chen, Lisa Derosa +66 more

Deep learning-based prediction of the T cell receptor–antigen binding specificity

Nature Machine Intelligence(2021)10.1038/s42256-021-00383-2

N/A

0.857DataRank · unranked

301 citations

Ze Zhang, James Zhu, Yunguan Wang, Peixin Jiang, Xue Xiao +8 more

Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-002891

N/A

0.854DataRank · unranked

296 citations

Ferdinandos Skoulidis, Meagan Montesion, Katja Schulze, Ilze Bāra, Vincent K. Shen +33 more

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-1824

N/A

0.807DataRank · unranked

216 citations

Melissa Burgess, Ruth Salazar, Edwin R. Parra, Jaime Rodrigues-Canales, Vanessa Bolejack +18 more

Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer

Annals of Oncology(2021)10.1016/j.annonc.2021.09.021

N/A

0.739DataRank · unranked

137 citations

Daniel J. McGrail, Salah-Eddine Bentebibel, Cara Haymaker, Angelo Ravelli, Marie‐Andrée Forget +31 more

Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.12.010

N/A

0.727DataRank · unranked

126 citations

Marcelo V. Negrão, Alexandre Reuben, Lorenzo Federico, Lixia Diao, Daniel J. McGrail +34 more

Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-1744

N/A

0.641DataRank · unranked

71 citations

Jianjun Zhang, Jiayin Wang, Alexandre Reuben, Wei Xu, Xin Yi +23 more

Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2020-000960

N/A

0.619DataRank · unranked

61 citations

Kathryn Bollin, Mariana Petaccia de Macêdo, Fernando C. L. Carapeto, Kevin B. Kim, Jason Roszik +12 more

Addition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma (EXTEND): A Multicenter, Randomized Phase II Trial

Journal of Clinical Oncology(2024)10.1200/jco.24.00081

N/A

0.619DataRank · unranked

61 citations

Alexander D. Sherry, Bryan M. Fellman, Suyu Liu, Tharakeswara Bathala, Cara Haymaker +25 more

Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer

Nature Communications(2021)10.1038/s41467-021-26821-8

N/A

0.598DataRank · unranked

53 citations

Runzhe Chen, Ying Jin, Jun Li, Xin Hu, Jiexin Zhang +40 more

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

Cancers(2021)10.3390/cancers13102293

N/A

0.554DataRank · unranked

11 citations

Booyeon J. Han, Alyssa Williams, Katherine M. Jackson, R. Todd Jewell, Alexander Chacon +7 more

Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention

Gastroenterology(2024)10.1053/j.gastro.2024.01.016

N/A

0.515DataRank · unranked

30 citations

Fahriye Düzağaç, Nan Deng, Laura Reyes-Uribe, Kyle Chang, Wenhui Wu +14 more

High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC

Journal for ImmunoTherapy of Cancer(2024)10.1136/jitc-2024-008950

N/A

0.515DataRank · unranked

13 citations

Ruoxing Li, Ziyi Li, Runzhe Chen, Ajay Sheshadri, Hai T. Tran +12 more

Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception

Cancer Cell(2025)10.1016/j.ccell.2025.04.003

N/A

0.505DataRank · unranked

28 citations

Pingjun Chen, Muhammad Aminu, Jiànróng Lǐ, Junya Fujimoto, Yanhua Tian +47 more

Single-cell and spatial proteo-transcriptomic profiling reveals immune infiltration heterogeneity associated with neuroendocrine features in small cell lung cancer

Cell Discovery(2024)10.1038/s41421-024-00703-x

N/A

0.483DataRank · unranked

24 citations

Yuefeng Wu, Alexandre Reuben, Liang Zhu, Carl M. Gay, Qingzhe Wu +13 more

Expansion of Candidate HPV-Specific T Cells in the Tumor Microenvironment during Chemoradiotherapy Is Prognostic in HPV16+ Cancers

Cancer Immunology Research(2022)10.1158/2326-6066.cir-21-0119

N/A

0.406DataRank · unranked

14 citations

Molly B. El, Erica J. Lynn, Julianna Bronk, Tatiana V. Karpinets, Xiaogang Wu +40 more

A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma

Neuro-Oncology(2025)10.1093/neuonc/noaf079

N/A

0.394DataRank · unranked

9 citations

Andrea G. Manzanera, Caroline Duault, Edgar Gonzalez‐Kozlova, Lenika Lopez, Stuart A. Grossman +50 more

Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf -mutated melanoma

OncoImmunology(2021)10.1080/2162402x.2021.1992880

N/A

0.385DataRank · unranked

12 citations

Robert Szczepaniak‐Sloane, Russell G. Witt, Alexandre Reuben, Pierre Olivier Gaudreau, Miles C. Andrews +27 more

Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes

Cancer Innovation(2024)10.1002/cai2.112

N/A

0.330DataRank · unranked

8 citations

Runzhe Chen, Yang Liu, Junya Fujimoto, Lingzhi Hong, Alexandre Reuben +20 more

Phase I/II Study of the Aurora Kinase A Inhibitor Alisertib and Pembrolizumab in Refractory, Rb-Deficient Head and Neck Squamous Cell Carcinomas

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-2290

N/A

0.330DataRank · unranked

8 citations

Madison P. O’Hara, Laçin Yapindi, Peixin Jiang, Hai T. Tran, Alexandre Reuben +8 more

Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma

Journal of Experimental & Clinical Cancer Research(2022)10.1186/s13046-022-02361-x

N/A

0.312DataRank · unranked

7 citations

Jun Li, Junya Fujimoto, Lingzhi Hong, Xin Hu, Kelly Quek +18 more

Intratumoral neutrophil-to-lymphocyte ratio is mirrored by circulating neutrophil-to-lymphocyte ratio in non-small cell lung cancer

Journal for ImmunoTherapy of Cancer(2025)10.1136/jitc-2025-011458

N/A

0.302DataRank · unranked

6 citations

Young‐Hee Lee, Nathaniel Deboever, Marcelo V. Negrão, Hai T. Tran, Edwin Parra +17 more

Spontaneous tumor regression and immunotherapy response demonstrate clonal T-cell expansion in Merkel cell carcinoma

npj Precision Oncology(2025)10.1038/s41698-025-00987-6

N/A

0.165DataRank · unranked

2 citations

John W Roman, Mairead Baker, Natasha T. Hill, Jennifer L. Marté, James L. Gulley +5 more

STEGG: Structural TCR-pMHC ensemble generator and gallery

Journal of Molecular Biology(2026)10.1016/j.jmb.2026.169762

N/A

0DataRank · unranked

0 citations

Alexander W. Bock, Mauricio Menegatti Rigo, Chengxuan Zou, Alexandre Reuben, Lydia E. Kavraki +1 more

Genomic and TCR Repertoire Intratumor Heterogeneity of Small-cell Lung Cancer and its Impact on Survival

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.30.180844

N/A

0DataRank · unranked

0 citations

Runzhe Chen, Ying Jin, Jun Li, Jiexin Zhang, Junya Fujimoto +32 more

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

Frontiers in Immunology(2021)10.3389/fimmu.2021.659625

N/A

0DataRank · unranked

17 citations

Patrick K. Reville, Xianli Jiang, Hui Yang, Alexandre Reuben, Jin S. Im +6 more

Genomic and TCR Repertoire Intratumor Heterogeneity of Small-cell Lung Cancer and its Impact on Survival

Research Square(2021)10.21203/rs.3.rs-148314/v1

N/A

0DataRank · unranked

0 citations

Runzhe Chen, Ying Jin, Jun Li, Jiexin Zhang, Junya Fujimoto +36 more

Candidate HPV-Specific T-Cells Expand in the Tumor Microenvironment During Chemoradiotherapy

Research Square(2021)10.21203/rs.3.rs-105933/v1

N/A

0DataRank · unranked

0 citations

Molly B. El Alam, Erica J. Lynn, Julianna K. Edwards, Tatiana V. Karpinets, Xiaogang Wu +39 more

Immunogenomic Intertumor Heterogeneity Across Primary and Metastatic Sites in a Patient With Lung Adenocarcinoma

Research Square(2021)10.21203/rs.3.rs-970663/v1

N/A

0DataRank · unranked

0 citations

Jun Li, Junya Fujimoto, Xin Hu, Kelly Quek, Ming Tang +17 more

Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma

medRxiv(2021)10.1101/2021.08.01.21260883

N/A

0DataRank · unranked

0 citations

Jun Li, Junya Fujimoto, Xin Hu, Kelly Quek, Ming Tang +17 more

Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1248

N/A

0DataRank · unranked

80 citations

Donastas Sakellariou-Thompson, Marie‐Andrée Forget, Emi Sei, Tara G. Hughes, Alexandre Reuben +15 more

Bayesian Hierarchical Quantile Regression with Application to Characterizing the Immune Architecture of Lung Cancer

Biometrics(2022)10.1111/biom.13774

N/A

0DataRank · unranked

2 citations

Christine B. Peterson, Yang Ni, Alexandre Reuben, Jiexin Zhang, Jianjun Zhang +3 more

A novel statistical method for decontaminating T-cell receptor sequencing data

Briefings in Bioinformatics(2023)10.1093/bib/bbad230

N/A

0DataRank · unranked

3 citations

Mehmet Altan, Alexandre Reuben, Ruitao Lin, John V. Heymach, Hai T. Tran +6 more

Data from Expansion of Candidate HPV-Specific T Cells in the Tumor Microenvironment during Chemoradiotherapy Is Prognostic in HPV16+ Cancers

(2023)10.1158/2326-6066.c.6550526

N/A

0DataRank · unranked

0 citations

Molly B. El, Erica J. Lynn, Julianna Bronk, Tatiana V. Karpinets, Xiaogang Wu +40 more

Supplemental Tables from Expansion of Candidate HPV-Specific T Cells in the Tumor Microenvironment during Chemoradiotherapy Is Prognostic in HPV16+ Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/2326-6066.22544087.v1

Top 100%

0DataRank

Top 100%0 citations

Molly B. El, Erica J. Lynn, Julianna Bronk, Tatiana V. Karpinets, Xiaogang Wu +40 more

Supplementary Figure from Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer

(2023)10.1158/2159-8290.22541815

Top 100%

0DataRank

Top 100%0 citations

Donastas Sakellariou-Thompson, Marie‐Andrée Forget, Emi Sei, Tara G. Hughes, Alexandre Reuben +15 more

Adding Metastasis-Directed Therapy to Standard-of-Care Systemic Therapy for Oligometastatic Breast Cancer (EXTEND): A Multicenter, Randomized Phase 2 Trial

International Journal of Radiation Oncology*Biology*Physics(2024)10.1016/j.ijrobp.2024.10.030

N/A

0DataRank · unranked

21 citations

Alexander D. Sherry, Bryan Fellman, Suyu Liu, Tharakeswara Bathala, Cara Haymaker +19 more

Continuous Androgen Deprivation Therapy with or Without Metastasis-directed Therapy for Oligometastatic Prostate Cancer: The Multicenter Phase 2 Randomized EXTEND Trial

European Urology(2025)10.1016/j.eururo.2025.07.006

N/A

0DataRank · unranked

24 citations

Bilal A. Siddiqui, Cara Haymaker, Bryan Fellman, Marina Nayeli Medina-Rosales, Tharakeswara Bathala +26 more

STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures

Computational and Structural Biotechnology Journal(2025)10.1016/j.csbj.2025.09.004

N/A

0DataRank · unranked

7 citations

Minying Zhang, Peixin Jiang, Amanda Kay Montoya, Emily Bontekoe, Barbara Nassif Rausseo +3 more

TCR-pMHC Binding Specificity Prediction From Structure Using Graph Neural Networks

IEEE Transactions on Computational Biology and Bioinformatics(2025)10.1109/tcbbio.2024.3504235

N/A

0DataRank · unranked

12 citations

Anja Conev, Maurício Rigo, Alexandre Reuben, Lydia E. Kavraki, Jared K. Slone

Rapid laser ablation-based fabrication of high-density polymer microwell arrays for high-throughput cellular studies

Lab on a Chip(2025)10.1039/d4lc01058b

N/A

0DataRank · unranked

2 citations

Kavya L. Singampalli, Amit S. Niyogi, Amanda Kay Montoya, Alexandre Reuben, Peter B. Lillehoj +1 more

Alexandre Reuben

Indexed papers

Top data-sharing exemplar

Papers