Ralph H. Hruban

Also affiliated with Johns Hopkins Medicine

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

10.5Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Papers

Driven by 55 papers — median percentile 95. Top paper: “Proteogenomic characterization of pancreatic ductal adenocarcinoma”.

Proteogenomic characterization of pancreatic ductal adenocarcinoma

Cell(2021)10.1016/j.cell.2021.08.023

N/A

7.9DataRank · unranked

606 citations

Chen Huang, Daniel Cui Zhou, Yingwei Hu, T. Mamie Lih, Sara R. Savage +95 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

Science(2011)10.1126/science.1206923

N/A

1.1DataRank · unranked

1689 citations

Mitchell J. Frederick, Curtis R. Pickering, Chetan Bettegowda, Kyle Chang, Ryan J. Li +29 more

Altered Telomeres in Tumors with ATRX and DAXX Mutations

Science(2011)10.1126/science.1207313

N/A

1.0DataRank · unranked

1064 citations

Roeland F. de Wilde, Yuchen Jiao, Alison P. Klein, Barish H. Edil, Chanjuan Shi +20 more

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

Science(2020)10.1126/science.abb9601

N/A

0.977DataRank · unranked

673 citations

Adam H. Buchanan, Isaac Kinde, Andrew Warren, Ashley Honushefsky, Ariella Cohain +35 more

Exploration of Global Gene Expression Patterns in Pancreatic Adenocarcinoma Using cDNA Microarrays

The American Journal of Pathology(2003)10.1016/s0002-9440(10)63911-9

N/A

0.925DataRank · unranked

475 citations

Anirban Maitra, Mari Olsen, Anson W. Lowe, N. Tjarda Van Heek, Christophe Rosty +18 more

CODA: quantitative 3D reconstruction of large tissues at cellular resolution

Nature Methods(2022)10.1038/s41592-022-01650-9

N/A

0.782DataRank · unranked

183 citations

Alicia M. Braxton, Mia P. Grahn, Kyu Sang Han, Jaanvi Mahesh Babu, Rebecca Reichel +14 more

The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer

Cancer Discovery(2023)10.1158/2159-8290.cd-21-1252

N/A

0.772DataRank · unranked

171 citations

Christopher Douville, Yuxuan Wang, Maria Popoli, Janine Ptak, Natalie Silliman +18 more

Machine learning to detect the SINEs of cancer

Science Translational Medicine(2024)10.1126/scitranslmed.adi3883

N/A

0.767DataRank · unranked

22 citations

Kamel Lahouel, Albert Kuo, Haley Grant, Bracha Erlanger Avigdor, Samuel D. Curtis +33 more

Genomic characterization of malignant progression in neoplastic pancreatic cysts

Nature Communications(2020)10.1038/s41467-020-17917-8

N/A

0.744DataRank · unranked

142 citations

Noushin Niknafs, Catherine G. Fischer, Wenzel M. Hackeng, Violeta Beleva Guthrie, Waki Hosoda +33 more

The Evolutionary Origins of Recurrent Pancreatic Cancer

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1508

N/A

0.732DataRank · unranked

131 citations

Marc A. Attiyeh, Jeffrey M. Gerold, Alvin P. Makohon-Moore, Akimasa Hayashi, Jungeui Hong +17 more

Assessing aneuploidy with repetitive element sequencing

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1910041117

N/A

0.663DataRank · unranked

82 citations

Joshua D. Cohen, Janine Ptak, Maria Popoli, Joy Schaefer, Natalie Silliman +17 more

Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms

The Journal of Pathology(2020)10.1002/path.5515

N/A

0.581DataRank · unranked

47 citations

María A. Trujillo, Kohei Fujikura, Miao‐Zhen Qiu, Fei Chen, Matthäus Felsenstein +14 more

A mucus production programme promotes classical pancreatic ductal adenocarcinoma

Gut(2024)10.1136/gutjnl-2023-329839

N/A

0.533DataRank · unranked

34 citations

Georgi N. Yordanov, Yuan Hao, Astrid Deschênes, Juliene Hinds, Pascal Belleau +10 more

Defining a minimum number of examined lymph nodes improves the prognostic value of lymphadenectomy in pancreas ductal adenocarcinoma

HPB(2020)10.1016/j.hpb.2020.08.016

N/A

0.489DataRank · unranked

25 citations

Shanshan Gao, Ross M. Beckman, Ding Ding, Michael Wright, Zhiyao Chen +15 more

Comprehensive DNA Methylation Analysis Indicates That Pancreatic Intraepithelial Neoplasia Lesions Are Acinar-Derived and Epigenetically Primed for Carcinogenesis

Cancer Research(2023)10.1158/0008-5472.can-22-4052

N/A

0.477DataRank · unranked

23 citations

Brian M. Mears, H. Carlo Maurer, Adrian Idrizi, Kasper D. Hansen, Elizabeth D. Thompson +5 more

Downregulation of 5‐hydroxymethylcytosine is an early event in pancreatic tumorigenesis

The Journal of Pathology(2021)10.1002/path.5682

N/A

0.449DataRank · unranked

19 citations

Zainab I. Alruwaii, Michael C. Haffner, María A. Trujillo, Nicholas J. Roberts, Seung‐Mo Hong +10 more

3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.03.606493

N/A

0.357DataRank · unranked

8 citations

Cristina Almagro-Pérez, Valentina Matos, André Forjaz, Alicia M. Braxton, Lucie Dequiedt +14 more

Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.27.525553

N/A

0.330DataRank · unranked

8 citations

Ashley Kiemen, Mia P. Grahn, André Forjaz, Jaanvi Mahesh Babu, Lily Zheng +36 more

Somatic loss of ATM is a late event in pancreatic tumorigenesis

The Journal of Pathology(2023)10.1002/path.6136

N/A

0.293DataRank · unranked

4 citations

Zhengdong Jiang, Danielle Hutchings, Valentyna Kryklyva, Christian Gauthier, Kohei Fujikura +18 more

Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma

Clinical Proteomics(2022)10.1186/s12014-022-09373-x

N/A

0.241DataRank · unranked

4 citations

Yingwei Hu, Lijun Chen, Michael Schnaubelt, Daniel Cui Zhou, Yize Li +15 more

Minimizing and quantifying uncertainty in AI-informed decisions: Applications in medicine

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2424203122

N/A

0.241DataRank · unranked

4 citations

Sambit Panda, Adam Li, Haoyin Xu, Yuhang Bai, Itsuki Ogihara +29 more

identifying cancer patients from GC-patterned fragment ends of cell-free DNA

medRxiv(2022)10.1101/2022.08.02.22278319

N/A

0.222DataRank · unranked

3 citations

Mahmoud Summers, Joshua D. Cohen, Yuxuan Wang, Nadine Nehme, Maria Popoli +17 more

Islands of genomic stability in the face of genetically unstable metastatic cancer

PLoS ONE(2024)10.1371/journal.pone.0298490

N/A

0.185DataRank · unranked

2 citations

Jiaying Lai, Alyza Skaist, Yan Zhang, Selina Shiqing K. Teh, Nicholas J. Roberts +8 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer

Histopathology(2022)10.1111/his.14839

N/A

0DataRank · unranked

16 citations

Young Geun Choi, Alicia M. Braxton, Cristina Almagro Pérez, Sarah E. Graham, Mia P. Grahn +7 more

Endoplasmic stress‐inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: A case‐control study and meta‐analysis

International Journal of Cancer(2021)10.1002/ijc.33883

N/A

0DataRank · unranked

25 citations

Shiro Kohi, Toshiya Abe, Mohamad Dbouk, Anne M. Macgregor‐Das, Chiho Koi +9 more

A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pancreatic Cysts

Annals of Surgery(2023)10.1097/sla.0000000000005904

N/A

0DataRank · unranked

58 citations

Abigail I. Wald, Daniel M. Spagnolo, Melissa A. Melan, Maria Grupillo, Yi-Tak Lai +49 more

Pancreatic Cancer Imaging: A New Look at an Old Problem

Current Problems in Diagnostic Radiology(2020)10.1067/j.cpradiol.2020.08.002

N/A

0DataRank · unranked

33 citations

Seyoun Park, Satomi Kawamoto, Alan Yuille, Ralph H. Hruban, Elliot K. Fishman +1 more

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

JCI Insight(2023)10.1172/jci.insight.169868

N/A

0DataRank · unranked

17 citations

Qizhi Zheng, Jessica Hicks, Levent Trabzonlu, Büşra Özbek, Tracy Jones +13 more

Detection of Pancreatic Ductal Adenocarcinoma-Associated Proteins in Serum

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100687

N/A

0DataRank · unranked

16 citations

Liwei Cao, Parham Minoo, Gilbert S. Omenn, Ralph H. Hruban, Daniel W. Chan +3 more

RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase–associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas

Gastroenterology(2023)10.1053/j.gastro.2023.02.006

N/A

0DataRank · unranked

9 citations

Ralph H. Hruban, Lodewijk A.A. Brosens, Vincenzo Condello, Marina N. Nikiforova, Aatur D. Singhi +23 more

Three‐dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding

The Journal of Pathology(2020)10.1002/path.5474

N/A

0DataRank · unranked

34 citations

Seung‐Mo Hong, DongJun Jung, Michaël Noë, Ashley Kiemen, Pei‐Hsun Wu +5 more

Pancreatic acinar cell carcinomas and mixed acinar-neuroendocrine carcinomas are more clinically aggressive than grade 1 pancreatic neuroendocrine tumours

Pathology(2020)10.1016/j.pathol.2020.01.437

N/A

0DataRank · unranked

18 citations

Jacqueline A. Brosnan‐Cashman, Jiyoon Kim, Soyeon An, Kyoung Bun Lee, Haeryoung Kim +7 more

Intraductal pancreatic cancer is less responsive than cancer in the stroma to neoadjuvant chemotherapy

Modern Pathology(2020)10.1038/s41379-020-0572-6

N/A

0DataRank · unranked

19 citations

Danielle Hutchings, Alicia M. Braxton, Qingfeng Zhu, Daniel A. Laheru, Ralph H. Hruban +3 more

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.20.529259

N/A

0DataRank · unranked

5 citations

Qizhi Zheng, Jessica Hicks, Levent Trabzonlu, Büşra Özbek, Tracy Jones +13 more

Simultaneous CRISPR-Cas9-induced double strand breaks are lethal in models of pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.03.535384

N/A

0DataRank · unranked

4 citations

Akhil Kotwal, Alexis Bennett, Eitan Halper‐Stromberg, Laura Morsberger, Saum Zamani +14 more

Data from An In vivo Platform for Translational Drug Development in Pancreatic Cancer

(2023)10.1158/1078-0432.c.6518317.v1

Top 100%

0DataRank

Top 100%0 citations

Antonio Jimeno, George Cusatis, Xianfeng Zhang, Christine A. Iacobuzio–Donahue, Collins Karikari +18 more

Data from Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas

(2023)10.1158/1078-0432.c.6520064.v1

N/A

0DataRank · unranked

0 citations

Noriyuki Omura, Audrey Vincent, Ang Li, Spencer Knight, Jun Yu +3 more

Medullary Pancreatic Carcinoma Due to Somatic POLE Mutation

Pancreas(2020)10.1097/mpa.0000000000001588

N/A

0DataRank · unranked

26 citations

Esther ter Linden, Leonie I. Kroeze, Richarda M. de Voer, Berit Kolk, Martijn W.J. Stommel +8 more

Performance of explainable artificial intelligence in guiding the management of patients with a pancreatic cyst

Pancreatology(2024)10.1016/j.pan.2024.09.001

N/A

0DataRank · unranked

8 citations

Felipe Oviedo, Caleb Robinson, Linda C. Chu, Satomi Kawamoto, Elham Afghani +13 more

CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers

NAR Cancer(2024)10.1093/narcan/zcae028

N/A

0DataRank · unranked

7 citations

Kirsten Bowland, Eitan Halper‐Stromberg, Akhil Kotwal, Alexis Bennett, Alyza Skaist +14 more

Detection of Circulating Tumor DNA in Patients with Pancreatic Cancer Using Digital Next-Generation Sequencing

Journal of Molecular Diagnostics(2020)10.1016/j.jmoldx.2020.02.010

N/A

0DataRank · unranked

21 citations

Jun Yu, Koji Tamura, Toshiya Abe, Masaya Suenaga, Koji Shindo +17 more

Reversible chemoresistance of pancreatic cancer grown as spheroids

Journal of Chemotherapy(2024)10.1080/1120009x.2024.2402177

N/A

0DataRank · unranked

1 citations

Alexis L. Norris, Yi Zhong, Asma Begum, Hong Liang, Marija Debeljak +11 more

Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0133

N/A

0DataRank · unranked

130 citations

Lindsey A. Baker, Astrid Deschênes, Benno Traub, Giuseppina Caligiuri, Dennis Plenker +22 more

Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression

Cancer Cell(2025)10.1016/j.ccell.2025.08.001

N/A

0DataRank · unranked

12 citations

T. Mamie Lih, Jae W. Lee, Takao Ohtsuka, Yuto Hozaka, Mari Mino–Kenudson +20 more

Prognostic Features in Surgically Resected Well-Differentiated Pancreatic Neuroendocrine Tumors: an Analysis of 904 Patients with 7882 Person-Years of Follow-Up

Endocrine Pathology(2025)10.1007/s12022-025-09866-z

N/A

0DataRank · unranked

8 citations

Eric D. Young, Amanda L. Blackford, Pengfei Wu, Richard A. Burkhart, William R. Burns +14 more

Recurrent BEND2 Fusion Genes Identified by Whole Transcriptome Sequencing of Nonfunctional Pancreatic Neuroendocrine Tumors Correlate With Poor Patient Prognosis

Modern Pathology(2025)10.1016/j.modpat.2025.100863

N/A

0DataRank · unranked

5 citations

Craig Nichols, Danielle Hutchings, Diana Bell, Abigail I. Wald, Katelyn Smith +50 more

Recent Trends in the Incidence and Survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results Analysis

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa004

N/A

0DataRank · unranked

261 citations

Marcia Irene Canto, Alison P. Klein, Ralph H. Hruban, Michael Goggins, Amanda L. Blackford

Mild Dilatation of the Main Pancreatic Duct Is a Risk Factor for Progression to Pancreatic Cancer in High-Risk Individuals

Gastro Hep Advances(2025)10.1016/j.gastha.2025.100802

N/A

0DataRank · unranked

2 citations

Helena Saba, Amanda L. Blackford, Mohamad Dbouk, Linda C. Chu, Jin He +5 more

High-Sensitive Spatial Proteomics for Pancreatic Cancer Progression Analysis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.01.651678

N/A

0DataRank · unranked

1 citations

Zhenyu Sun, Yingwei Hu, Trung Hoàng, Decapite Christine, Smith Katelyn +7 more

Prognostic Features in Surgically Resected Well-Differentiated Pancreatic Neuroendocrine Tumors: An Analysis of 904 Patients with 7882 Person-Years of Follow-Up

medRxiv(2025)10.1101/2025.04.01.25325055

N/A

0DataRank · unranked

0 citations

Eric D. Young, Amanda L. Blackford, Pengfei Wu, Richard A. Burkhart, William R. Burns +14 more

TP53/KRAS variant allele frequency ratio predicts advanced disease in mucin-producing cystic neoplasms of the pancreas

American Journal of Clinical Pathology(2025)10.1093/ajcp/aqaf133

N/A

0DataRank · unranked

0 citations

Elham Afghani, Marcia Irene Canto, Jing Zhu, Syed Z. Ali, Laura D. Wood +5 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

Ralph H. Hruban

Indexed papers

Top data-sharing exemplar

Papers