Sara J. Buhrlage

Also affiliated with Boston VA Research Institute, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism”.

Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism

Scientific Reports(2020)10.1038/s41598-020-62076-x

N/A

3.0DataRank · unranked

127 citations

Xiaoxi Liu, Robert S. Magin, Laura M. Doherty, Wai Cheung Chan, Scott B. Ficarro +22 more

SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas

Blood Cancer Journal(2020)10.1038/s41408-020-0277-6

N/A

1.4DataRank · unranked

48 citations

Xia Liu, Jiaji G. Chen, Lian Xu, Nickolas Tsakmaklis, Maria Demos +19 more

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma

Journal of Clinical Investigation(2022)10.1172/jci151666

N/A

1.0DataRank · unranked

32 citations

Susan Klaeger, Phuong M. Le, Keegan Korthauer, Jingwei Cheng, Varsha Ananthapadmanabhan +41 more

Akkermansia muciniphila phospholipid induces homeostatic immune responses

Nature(2022)10.1038/s41586-022-04985-7

N/A

0.899DataRank · unranked

400 citations

Chelsi D. Cassilly, Xiaoxi Liu, Sung‐Moo Park, Betsabeh Khoramian Tusi, Xiangjun Chen +10 more

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

eLife(2022)10.7554/elife.72879

N/A

0.590DataRank · unranked

50 citations

Caitlin E. Mills, Sarah A. Boswell, Xiaoxi Liu, Charles Tapley Hoyt, Benjamin M. Gyori +3 more

Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors

Cell chemical biology(2020)10.1016/j.chembiol.2020.09.005

N/A

0.564DataRank · unranked

42 citations

Katherine A. Donovan, Nathan J. Schauer, Xiaoxi Liu, Wanyi Hu, Anthony C. Varca +3 more

The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance

Blood(2021)10.1182/blood.2021011405

N/A

0.505DataRank · unranked

28 citations

Jinhua Wang, Li Tan, Manit Munshi, Xia Liu, Amanda Kofides +17 more

A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas

Blood Advances(2022)10.1182/bloodadvances.2021006147

N/A

0.416DataRank · unranked

15 citations

Xia Liu, Amanda Kofides, Nickolas Tsakmaklis, Maria Luisa Guerrera, Zachary R. Hunter +18 more

Identification of deubiquitinase inhibitors via high-throughput screening using a fluorogenic ubiquitin-rhodamine assay

STAR Protocols(2021)10.1016/j.xpro.2021.100896

N/A

0.360DataRank · unranked

10 citations

Dominick Casalena, Douglas S. Auld, Sara J. Buhrlage, Anthony C. Varca

Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas

Neuro-Oncology Advances(2022)10.1093/noajnl/vdac049

N/A

0.241DataRank · unranked

4 citations

Alexander Brown, Emily Addleson, Clara Ives, Ella Trumper, Kristine Pelton +9 more

Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.108223

N/A

0.104DataRank · unranked

1 citations

Isabella Jaen Maisonet, Kwangwoon Lee, Sara J. Buhrlage, Philip A. Cole, Reina Iwase

Expanding the HDAC druggable landscape beyond enzymatic activity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.07.519454

N/A

0.104DataRank · unranked

1 citations

Soon Gang Choi, Salvador Sierra, Tina O’Grady, Mario de la Fuente Revenga, Florent Laval +45 more

Strategies for Competitive Activity‐Based Protein Profiling in Small Molecule Inhibitor Discovery and Characterization

Israel Journal of Chemistry(2023)10.1002/ijch.202200113

N/A

0DataRank · unranked

4 citations

Mona Sharafi, Wei Pin Teh, Ariana S. Bratt, Sara J. Buhrlage, Jarrod A. Marto +1 more

Synergy between BRD9- and IKZF3-Targeting as a Therapeutic Strategy for Multiple Myeloma

Cancers(2024)10.3390/cancers16071319

N/A

0DataRank · unranked

8 citations

Swati Garg, Wei Ni, Martin Sattler, Dana Sanchez, Chengcheng Meng +8 more

Open-source electrophilic fragment screening platform to identify chemical starting points for UCHL1 covalent inhibitors

SLAS DISCOVERY(2024)10.1016/j.slasd.2024.100198

N/A

0DataRank · unranked

0 citations

Zachary H Marto, Nicholas M. Girardi, De‐Yao Deng, Isabella Jaen Maisonet, Guillaume Adelmant +10 more

Pharmacologic interrogation of USP28 cellular function in p53 signaling

Cell chemical biology(2025)10.1016/j.chembiol.2025.08.002

N/A

0DataRank · unranked

3 citations

Susan Kilgas, Maria I. Tarazona Guzman, Robert S. Magin, Isabella Jaen Maisonet, Cara Ann Starnbach +12 more

Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7)

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2510496122

N/A

0DataRank · unranked

3 citations

Mona Sharafi, Emilie J. Korchak, Andres Salazar‐Chaparro, Ariana S. Bratt, Tvesha Parikh +9 more

Structural basis of VCP-VCPIP1-p47 ternary complex in Golgi maintenance

Nature Communications(2025)10.1038/s41467-025-63161-3

N/A

0DataRank · unranked

3 citations

Moritz Hunkeler, Ariana S. Bratt, Hong Yue, Isabella Jaen Maisonet, Eric S. Fischer +2 more

Functional spectrum of USP7 pathogenic variants in Hao–Fountain syndrome: Insights into the enzyme’s activity, stability, and allosteric modulation

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2510252122

N/A

0DataRank · unranked

4 citations

Mona Sharafi, Isabella Jaen Maisonet, Andres Salazar‐Chaparro, И. В. Семенова, Hamza Khan +6 more

Repurposing of Kinase Inhibitors for Treatment of COVID-19

Pharmaceutical Research(2020)10.1007/s11095-020-02851-7

N/A

0DataRank · unranked

153 citations

Alexander Parent, Priscilla L. Yang, Martin Sattler, Qingsong Liu, Qingwang Liu +6 more

Dual CARM1-and IKZF3-targeting: A novel approach to multiple myeloma therapy

Molecular Therapy Oncology(2025)10.1016/j.omton.2025.200952

N/A

0DataRank · unranked

0 citations

Swati Garg, Basudev Chowdhury, Martin Sattler, Dana Sanchez, Chengcheng Meng +13 more

Inhibition of the deubiquitinase USP10 induces degradation of SYK

British Journal of Cancer(2020)10.1038/s41416-020-0731-z

N/A

0DataRank · unranked

33 citations

Chengcheng Meng, Ellen Weisberg, Abigail E. Case, Ilaria Lamberto, Robert S. Magin +9 more

Effects of the multi‐kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia

Journal of Cellular and Molecular Medicine(2020)10.1111/jcmm.14927

N/A

0DataRank · unranked

28 citations

Chengcheng Meng, Abigail E. Case, Hong L. Tiv, Prafulla C. Gokhale, Sara J. Buhrlage +9 more

Discovery of a Selective, Covalent IRAK1 Inhibitor with Antiproliferative Activity in MYD88 Mutated B-Cell Lymphoma

ACS Medicinal Chemistry Letters(2020)10.1021/acsmedchemlett.0c00378

N/A

0DataRank · unranked

28 citations

Guang Yang, Li Wang, Scott B. Ficarro, Sara J. Buhrlage, Hao Wu +4 more

Chemoproteomic methods for covalent drug discovery

Chemical Society Reviews(2021)10.1039/d1cs00231g

N/A

0DataRank · unranked

77 citations

Shabnam Sharifzadeh, Sara J. Buhrlage, Jarrod A. Marto, Wai Cheung Chan

Targeting oncoproteins with a positive selection assay for protein degraders

Science Advances(2021)10.1126/sciadv.abd6263

N/A

0DataRank · unranked

47 citations

Leslie Duplaquet, Benjamin L. Lampson, Adam C. Wang, Amin H. Sabet, Mette Ishoey +21 more

Small molecules as tools for functional assessment of deubiquitinating enzyme function

Cell chemical biology(2021)10.1016/j.chembiol.2021.04.021

N/A

0DataRank · unranked

16 citations

Xiaoxi Liu, Alejandra Felix, Ariana S. Bratt, Wai Cheung Chan, Sara J. Buhrlage +1 more

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.06.455458

N/A

0DataRank · unranked

2 citations

Caitlin E. Mills, Sarah A. Boswell, Xiaoxi Liu, Charles Tapley Hoyt, Benjamin M. Gyori +3 more

On-Chip Preconcentration Microchip Capillary Electrophoresis Based CE-PRM-LIVE for High-Throughput Selectivity Profiling of Deubiquitinase Inhibitors

Analytical Chemistry(2022)10.1021/acs.analchem.2c01337

N/A

0DataRank · unranked

6 citations

J. Scott Mellors, Wai Cheung Chan, J. Will Thompson, Scott B. Ficarro, Isidoro Tavares +7 more

Accelerating inhibitor discovery for deubiquitinating enzymes

Nature Communications(2023)10.1038/s41467-023-36246-0

N/A

0DataRank · unranked

81 citations

Xiaoxi Liu, Robert S. Magin, Nicholas M. Girardi, Scott B. Ficarro, Wanyi Hu +15 more

Proteomic approaches to study ubiquitinomics

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms(2023)10.1016/j.bbagrm.2023.194940

N/A

0DataRank · unranked

23 citations

He Zhu, Sara J. Buhrlage, Jarrod A. Marto, Indrajit Sahu

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle

Journal of Virology(2023)10.1128/jvi.01763-22

N/A

0DataRank · unranked

7 citations

Praneet Sandhu, Jason P. Wong, Aadra P. Bhatt, Xiaoxi Liu, Sara J. Buhrlage +4 more