Li Gan

Also affiliated with MIND Research Institute, Weill Cornell Medicine

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.5Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

Nature Genetics(2023)10.1038/s41588-023-01572-y

Top 14%

1.5DataRank

Top 14%84 citations

Ziyu Lu, Jasper Lee, Gábor Bányai, Sonya Anderson, Abdulraouf Abdulraouf +12 more

Papers

Driven by 43 papers — median percentile 86. Top paper: “Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration”.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Cell(2022)10.1016/j.cell.2021.12.041

N/A

5.7DataRank · unranked

346 citations

Jesús Madero‐Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konràd +25 more

A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states

Nature Neuroscience(2022)10.1038/s41593-022-01131-4

N/A

4.1DataRank · unranked

252 citations

Sydney M. Sattler, Cindy Huang, Olivia M. Teter, Kun Leng, Sayed Hadi Hashemi +14 more

Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue

Nature Biotechnology(2022)10.1038/s41587-022-01231-3

N/A

2.8DataRank · unranked

133 citations

Wen Hu, Anoushka Joglekar, Li Fan, Paul Collier, Careen Foord +25 more

A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

eLife(2020)10.7554/elife.51796

N/A

2.5DataRank · unranked

82 citations

Li Fan, Lay Kodama, Peter Sohn, Man Ying Wong, Gergey Alzaem Mousa +4 more

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

Nature Genetics(2023)10.1038/s41588-023-01572-y

Top 14%

1.5DataRank

Top 14%84 citations

Ziyu Lu, Jasper Lee, Gábor Bányai, Sonya Anderson, Abdulraouf Abdulraouf +12 more

Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice

Nature Communications(2021)10.1038/s41467-021-22501-9

N/A

0.808DataRank · unranked

218 citations

Mathieu Bourdenx, Enrique Luengo, Antonio Díaz, Peter Sohn, Xu Chen +16 more

Autophagy prevents microglial senescence

Nature Cell Biology(2023)10.1038/s41556-023-01168-y

N/A

0.807DataRank · unranked

24 citations

Bangyan Liu, Li Gan, Sadaf Amin

Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders

Molecular Neurodegeneration(2023)10.1186/s13024-023-00672-x

N/A

0.754DataRank · unranked

151 citations

Bangyan Liu, Subhash C. Sinha, Sadaf Amin, Li Gan, Yige Huang

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Molecular Neurodegeneration(2020)10.1186/s13024-019-0354-0

N/A

0.708DataRank · unranked

111 citations

Yaqiao Li, Chao Wang, Yinyan Tang, Sue‐Ann Mok, Richard Tsai +9 more

Functional characterization of Alzheimer’s disease genetic variants in microglia

Nature Genetics(2023)10.1038/s41588-023-01506-8

N/A

0.654DataRank · unranked

77 citations

Jia Wen, Han Yang, Ian Rees Jones, Xiaodong Zhu, Weifang Liu +22 more

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

Cell(2024)10.1016/j.cell.2024.03.015

N/A

0.654DataRank · unranked

77 citations

Alice Maria Giani, Jesus Madero-Perez, Zeping Zhao, Yuansong Wan, Avi J. Samelson +24 more

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

Neuron(2024)10.1016/j.neuron.2024.09.006

N/A

0.624DataRank · unranked

63 citations

Li Fan, Nessa Foxe, Kendra Norman, Man Ying Wong, Daphne Zhu +25 more

Tlr7 drives sex differences in age- and Alzheimer’s disease–related demyelination

Science(2024)10.1126/science.adk7844

N/A

0.571DataRank · unranked

44 citations

Lay Kodama, Li Fan, Daphne Zhu, Jingjie Zhu, Man Ying Wong +15 more

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.16.545386

N/A

0.561DataRank · unranked

41 citations

Nabeela Ariqat, Justin McKetney, Gita Rohanitazangi, C Bravo, Rudra Bose +22 more

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

Immunity(2025)10.1016/j.immuni.2025.05.023

N/A

0.483DataRank · unranked

24 citations

Chloe Lopez-Lee, Eileen Ruth S. Torres, Se-In Lee, Jingjie Zhu, Daphne Zhu +20 more

Novel avenues of tau research

Alzheimer s & Dementia(2024)10.1002/alz.13533

N/A

0.434DataRank · unranked

17 citations

Gal Bitan, Kathryn R. Bowles, Mirosław Bryś, Luc Buée, Mahmoud Bukar Maina +31 more

REV-ERBα regulates brain NAD+ levels and tauopathy via an NFIL3–CD38 axis

Nature Aging(2025)10.1038/s43587-025-00950-x

N/A

0.345DataRank · unranked

9 citations

Ryeonghwa Kang, Sohui Park, Ibrahim Olabayode Saliu, Maarten J. van Son, Jaymie R. Voorhees +11 more

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

学術講演梗概集. C-1, 構造III, 木質構造, 鉄骨構造, 鉄骨鉄筋コンクリート構造(2023)10.1101/2023.06.19.544278

N/A

0.330DataRank · unranked

8 citations

Alice Maria Giani, Jesús Madero‐Pérez, Zeping Zhao, Avi J. Samelson, Man Ying Wong +17 more

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.24.577107

N/A

0.312DataRank · unranked

7 citations

Li Fan, Nessa Foxe, Kendra Norman, Pearly Ye, Man Ying Wong +18 more

A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain

Cell Reports(2025)10.1016/j.celrep.2025.116198

N/A

0.295DataRank · unranked

6 citations

Wen Hu, Li Fan, Anoushka Joglekar, Yi He, Careen Foord +25 more

iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death

Molecular and Cellular Neuroscience(2024)10.1016/j.mcn.2024.103954

N/A

0.269DataRank · unranked

5 citations

Chao Wang, David Butler, Dulce Ovando Morales, Cathrine Petersen, Andrew J. Ambrose +13 more

DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity

Research Square(2023)10.21203/rs.3.rs-3454358/v1

N/A

0.241DataRank · unranked

4 citations

Hao Chen, Li Fan, Qi Guo, Man Ying Wong, Fangmin Yu +15 more

DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice

Molecular Neurodegeneration(2025)10.1186/s13024-025-00903-3

N/A

0.208DataRank · unranked

3 citations

Li Fan, Qi Guo, Man Ying Wong, Jingjie Zhu, Nessa Foxe +17 more

Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC-induced neurons with the V337M MAPT mutation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.08.425912

N/A

0.208DataRank · unranked

3 citations

Chao Wang, David Butler, Dulce Ovando Morales, Cathrine Petersen, Brian Chin +12 more

Pathogenic tau inhibits synaptic plasticity by blocking eIF4B-mediated local protein synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.11.675671

N/A

0.208DataRank · unranked

3 citations

Doyle Lokitiyakul, Ivy Tsz-Lo Wong, Kevin Schneider, Varun Sridhar, Durai Sellegounder +14 more

Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD

Communications Biology(2025)10.1038/s42003-025-08368-2

N/A

0.165DataRank · unranked

2 citations

Li Fan, Rowan Saloner, Jon Iker Etchegaray, Chad R. Altobelli, Sally Salomonsson +24 more

Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.17.448349

N/A

0.104DataRank · unranked

1 citations

Jesús Madero‐Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konràd +20 more

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

Journal of Clinical Investigation(2024)10.1172/jci169064

N/A

0DataRank · unranked

26 citations

Kristeen A. Pareja‐Navarro, Lei Yao, Jackson H. Chen, Ivy Tsz-Lo Wong, Rowan Saloner +15 more

Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury

Molecular Neurodegeneration(2024)10.1186/s13024-024-00733-9

N/A

0DataRank · unranked

22 citations

Karen Krukowski, Sarah Barker, Chao Wang, Yaqiao Li, Li Fan +13 more

Early life high fructose exposure disrupts microglia function and impedes neurodevelopment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.14.553242

N/A

0DataRank · unranked

6 citations

Allie Lipshutz, Zong-Lin Liu, Alissa Trzeciak, Isabella C. Miranda, Celia Martinez de la Torre +16 more

Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models

Neurobiology of Disease(2023)10.1016/j.nbd.2023.106263

N/A

0DataRank · unranked

39 citations

Wenjie Mao, Yuliya Voskobiynyk, Deanna Necula, Irene Lew, Cathrine Petersen +9 more

Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience

Nature Neuroscience(2023)10.1038/s41593-023-01315-6

N/A

0DataRank · unranked

290 citations

Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S. Torres, Gillian Carling +24 more

Early life high fructose impairs microglial phagocytosis and neurodevelopment

Nature(2025)10.1038/s41586-025-09098-5

N/A

0DataRank · unranked

25 citations

Allie Lipshutz, Celia Martinez de la Torre, Alissa Trzeciak, Zong-Lin Liu, Isabella C. Miranda +21 more

Familial natural short sleep mutations reduce Alzheimer pathology in mice

iScience(2022)10.1016/j.isci.2022.103964

N/A

0DataRank · unranked

23 citations

Nicholas W. Gentry, Thomas McMahon, Maya Yamazaki, Lorena Benitez-Rivera, Tammy Wang +4 more

Identification and development of cGAS inhibitors and their uses to treat Alzheimer's disease

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00536

N/A

0DataRank · unranked

14 citations

Ravi Kumar Nagiri, Li Gan, Subhash C. Sinha, Jazmín Alarcón‐Espósito

Sex Differences in Neurodegeneration: The Role of the Immune System in Humans

Biological Psychiatry(2021)10.1016/j.biopsych.2021.01.002

N/A

0DataRank · unranked

66 citations

Lay Kodama, Li Gan, Chloe Lopez-Lee

Astrocyte senescence promotes glutamate toxicity in cortical neurons

PLoS ONE(2020)10.1371/journal.pone.0227887

N/A

0DataRank · unranked

182 citations

Tal Oron, Fatouma Alimirah, Albert R. Davalos, Tara E. Tracy, Li Gan +3 more

Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia

Scientific Reports(2020)10.1038/s41598-020-70534-9

N/A

0DataRank · unranked

20 citations

Kai Liu, Faten A. Sayed, Jon Iker Etchegaray, Min Xie, Lihong Zhan +8 more

Functional characterization of Alzheimer’s disease genetic variants in microglia

UNC Libraries(2025)10.17615/jm1j-1y96

N/A

0DataRank · unranked

0 citations

Yang Sun, Xiaoyu Yang, Mirunalini Ravichandran, Han Yang, Jia Wen +22 more

Dopamine receptor 1-expressing cells in the ventral hippocampus encode cocaine-context associations

Research Square(2025)10.21203/rs.3.rs-8079719/v1

N/A

0DataRank · unranked

0 citations

Veronika Kondev, Arthur Godino, Brian T. Kipp, Evelyn Hennigan, Clara Casey +15 more

Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer’s disease

Cell Reports Medicine(2024)10.1016/j.xcrm.2023.101379

N/A

0DataRank · unranked

57 citations

Fei Wang, Jian Tang, Yadi Zhou, Zhimin Fu, Pengyue Zhang +8 more

Mechanisms of sex differences in Alzheimer’s disease

Neuron(2024)10.1016/j.neuron.2024.01.024

N/A

0DataRank · unranked

332 citations

Eileen Ruth S. Torres, Gillian Carling, Li Gan, Chloe Lopez-Lee

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.12.543777

N/A

0DataRank · unranked

4 citations

Kristeen A. Pareja‐Navarro, Lei Yao, Jackson H. Chen, Ivy Tsz-Lo Wong, Rowan Saloner +15 more

Li Gan

Indexed papers

Top data-sharing exemplar

Papers