Grant A. Challen

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Spatial Mapping of Hematopoietic Clones in Human Bone Marrow”.

Spatial Mapping of Hematopoietic Clones in Human Bone Marrow

Blood Cancer Discovery(2024)10.1158/2643-3230.bcd-23-0110

N/A

0.487DataRank · unranked

8 citations

Hannah C. Davis, Maggie J. Cox, Tyler M. Parsons, Samantha C. Burkart, Diane E. Bender +4 more

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow

Oncotarget(2020)10.18632/oncotarget.27564

N/A

0.457DataRank · unranked

20 citations

Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang +6 more

Dnmt3a is essential for hematopoietic stem cell differentiation

UNC Libraries(2020)10.17615/nj45-sr35

N/A

0.104DataRank · unranked

1 citations

Yue Lu, Jonathan S. Berg, Jaroslav Jelı́nek, Wei Li, Yuanxin Xi +13 more

Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling

Cell stem cell(2021)10.1016/j.stem.2021.03.002

N/A

0DataRank · unranked

320 citations

Katie A. Matatall, Duy T. Le, Bailee Kain, Xiaochen Long, Paweł Kuś +5 more

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Cancer Research(2021)10.1158/0008-5472.can-20-3761

N/A

0DataRank · unranked

52 citations

Bac Viet Le, Margaret Nieborowska-Skorska, Konstantin Golovine, Katherine Sullivan-Reed, Wangisa M.B. Dunuwille +30 more

LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1353

N/A

0DataRank · unranked

46 citations

Praveen Suraneni, Hamza Celik, Andrew Volk, Qiang Wen, Te Ling +20 more

A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1652

N/A

0DataRank · unranked

32 citations

Ethan Krug, Christine R. Zhang, Wentao Han, Nancy Issa, Won Kyun Koh +12 more

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.27.449656

N/A

0DataRank · unranked

14 citations

Angelo B. A. Laranjeira, Kangning Yang, Daniel A.C. Fisher, LaYow Yu, Anthony Z. Wang +8 more

Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a -Mutant Clonal Hematopoiesis

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0086

N/A

0DataRank · unranked

92 citations

Elizabeth Eudy, Matthew A. Loberg, Kira Young, Jayna J. Mistry, Kristina D. Mujica +5 more

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

Nature Cancer(2022)10.1038/s43018-022-00486-8

N/A

0DataRank · unranked

40 citations

Angelo B. A. Laranjeira, Kangning Yang, Daniel A.C. Fisher, LaYow Yu, Laure Poittevin De La Frégonnière +10 more

Txnip Enhances Fitness of Dnmt3a -Mutant Hematopoietic Stem Cells via p21

Blood Cancer Discovery(2022)10.1158/2643-3230.bcd-21-0132

N/A

0DataRank · unranked

22 citations

Elizabeth L. Ostrander, Ostap Kukhar, Cates Mallaney, Jiameng Sun, Emily Haussler +6 more

Effect of Clonal Hematopoiesis on Cardiovascular Disease in People Living with HIV

Experimental Hematology(2022)10.1016/j.exphem.2022.07.304

N/A

0DataRank · unranked

16 citations

Tyler M. Parsons, Samantha C. Burkart, Andrew L. Young, Kristine M. Erlandson, Katherine Tassiopoulos +6 more

Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a -Mutant Clonal Hematopoiesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.03.498502

N/A

0DataRank · unranked

1 citations

Elizabeth Eudy, Matthew A. Loberg, Kira Young, Jayna J. Mistry, Logan S. Schwartz +4 more

KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress

Research Square(2022)10.21203/rs.3.rs-2251777/v1

N/A

0DataRank · unranked

0 citations

Hassan Bjeije, Elisabeth Wilson, Aishwarya Krishnan, Wangisa Dunuwille, Tyler M. Parsons +11 more

KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress

Leukemia(2023)10.1038/s41375-023-01853-9

N/A

0DataRank · unranked

16 citations

Hassan Bjeije, Elisabeth R. Wilson, Aishwarya Krishnan, Wangisa M.B. Dunuwille, Tyler M. Parsons +11 more

Droplet Digital PCR for Oncogenic KMT2A Fusion Detection

Journal of Molecular Diagnostics(2023)10.1016/j.jmoldx.2023.09.006

N/A

0DataRank · unranked

6 citations

Hannah C. Davis, Grant A. Challen, Andrew L. Young

Data from TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

(2023)10.1158/0008-5472.c.6513157.v1

N/A

0DataRank · unranked

0 citations

Bac Viet Le, Margaret Nieborowska-Skorska, Konstantin Golovine, Katherine Sullivan-Reed, Wangisa M.B. Dunuwille +30 more

RSK1 dependency in FLT3-ITD acute myeloid leukemia

Blood Cancer Journal(2024)10.1038/s41408-024-01187-4

N/A

0DataRank · unranked

9 citations

Angelo B. A. Laranjeira, Christopher T. Letson, LaYow Yu, Fan He, Aarthi Jayanthan +5 more

BIRC5 upregulation enhances DNMT3A-mutant T-ALL cell survival and pathogenesis

Blood Neoplasia(2024)10.1016/j.bneo.2024.100040

N/A

0DataRank · unranked

1 citations

William C. Wilson, Hassan Bjeije, Nancy Issa, Wentao Han, Tyler M. Parsons +12 more

DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.15.613155

N/A

0DataRank · unranked

0 citations

Umeshkumar Vekariya, Monika M. Toma, Margaret Nieborowska-Skorska, Marie‐Christine Caron, Malgorzata Gozdecka +20 more

Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis

Nature Communications(2025)10.1038/s41467-025-57238-2

N/A

0DataRank · unranked

28 citations

Mohsen Hosseini, Jayna J. Mistry, Claudia Morganti, Taylor Mills, Xiurong Cai +16 more

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia

Nature Communications(2025)10.1038/s41467-024-55643-7

N/A

0DataRank · unranked

17 citations

Angelo B. A. Laranjeira, Christopher T. Letson, LaYow Yu, Shuyang Lin, Jared S. Fowles +20 more

Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity

Cell stem cell(2025)10.1016/j.stem.2025.06.010

N/A

0DataRank · unranked

6 citations

Won Kyun Koh, Jessica J. Harrison, Christine Zhang, Barbara Soares, Roberta Amato +10 more

Parallel Evolution of Leukemic Clones in Myeloproliferative Neoplasms

Research Square(2025)10.21203/rs.3.rs-8097141/v1

N/A

0DataRank · unranked

1 citations

Tyler M. Parsons, Aishwarya Krishnan, Infencia Xavier Raj, Andrew L. Young, David R O’Leary +4 more

JARID2 Inhibition Reprograms Human Hematopoietic Progenitor Cells To Enhance Bone Marrow Transplantation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.03.672211

N/A

0DataRank · unranked

0 citations

Hassan Bjeije, Hamza Celik, Michael P. Rettig, Nancy Issa, Andrew L. Young +11 more

Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness

Stem Cell Reports(2020)10.1016/j.stemcr.2020.02.011

N/A

0DataRank · unranked

94 citations

Ashley C. Kramer, Cates Mallaney, Hamza Celik, Won Kyun Koh, Jake Fairchild +4 more

JAK2 V617F Myeloproliferative Neoplasms Support Parallel Evolution of Independent Leukemic Clones

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.23.678057

N/A

0DataRank · unranked

0 citations

Aishwarya Krishnan, Infencia Xavier Raj, Andrew L. Young, David R O’Leary, Jason Arand +4 more

Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma

Retrovirology(2020)10.1186/s12977-020-00535-z

N/A

0DataRank · unranked

16 citations

Sydney L. Olson, John C. S. Harding, Hemalatha Sundaramoorthi, Youngsoo Kim, Tianyuan Zhou +4 more

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

Cell Reports(2020)10.1016/j.celrep.2020.108221

N/A

0DataRank · unranked

30 citations

Paulina Podszywalow‐Bartnicka, Silvia Maifrede, Katherine Sullivan-Reed, Margaret Nieborowska-Skorska, Konstantin Golovine +21 more