Brian G. Pierce

Also affiliated with National Institute of Standards and Technology, Advanced Bioscience Laboratories (United States), Institute for Bioscience and Biotechnology Research, University of Maryland, College Park

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

8.3Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

CoV3D: a database of high resolution coronavirus protein structures

Nucleic Acids Research(2020)10.1093/nar/gkaa731

Top 8%

2.7DataRank

Top 8%81 citations

Johnathan D. Guest, Rui Yin, Jared Adolf‐Bryfogle, William R. Schief, Brian G. Pierce +1 more

Papers

Driven by 49 papers — median percentile 79. Top paper: “CoV3D: a database of high resolution coronavirus protein structures”.

CoV3D: a database of high resolution coronavirus protein structures

Nucleic Acids Research(2020)10.1093/nar/gkaa731

Top 8%

2.7DataRank

Top 8%81 citations

Johnathan D. Guest, Rui Yin, Jared Adolf‐Bryfogle, William R. Schief, Brian G. Pierce +1 more

Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment

Proteins Structure Function and Bioinformatics(2021)10.1002/prot.26222

Top 9%

2.3DataRank

Top 9%127 citations

Guillaume Brysbaert, Théo Mauri, Nurul Nadzirin, Sameer Velankar, Raphaël A. G. Chaleil +95 more

Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment

Proteins Structure Function and Bioinformatics(2023)10.1002/prot.26609

Top 11%

1.9DataRank

Top 11%81 citations

Guillaume Brysbaert, Nessim Raouraoua, Paul A. Bates, Marco Giulini, Rodrigo V. Honorato +95 more

Benchmarking AlphaFold for protein complex modeling reveals accuracy determinants

Protein Science(2022)10.1002/pro.4379

N/A

0.885DataRank · unranked

365 citations

Brandon Y. Feng, Amitabh Varshney, Brian G. Pierce, Rui Yin

TCR3d 2.0: expanding the T cell receptor structure database with new structures, tools and interactions

Nucleic Acids Research(2024)10.1093/nar/gkae840

Top 30%

0.664DataRank

Top 30%26 citations

Melyssa Cheung, Ragul Gowthaman, M A Eisenberg, Brian M. Baker, Brian G. Pierce +1 more

Impact of AlphaFold on Structure Prediction of Protein Complexes: The CASP15-CAPRI Experiment

Utrecht University Repository (Utrecht University)(2023)10.22541/au.168888815.53957253/v1

Top 36%

0.540DataRank

Top 36%17 citations

Guillaume Brysbaert, Nessim Raouraoua, Paul A. Bates, Marco Giulini, Rodrigo V. Honorato +95 more

Structural Features of Antibody-Peptide Recognition

Frontiers in Immunology(2022)10.3389/fimmu.2022.910367

N/A

0.510DataRank · unranked

29 citations

Rui Yin, Gilad Ofek, Brian G. Pierce, Jessica H. Lee

Preexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy

Cancer Discovery(2024)10.1158/2159-8290.cd-23-0798

N/A

0.505DataRank · unranked

28 citations

Yue Zhang, Oscar E. Ospina, Matt D. Nichols, Victoria A. Chu, Álvaro de Mingo Pulido +31 more

Structure-Based and Rational Design of a Hepatitis C Virus Vaccine

Viruses(2021)10.3390/v13050837

N/A

0.483DataRank · unranked

24 citations

Brian G. Pierce, Johnathan D. Guest

Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants

Frontiers in Immunology(2022)10.3389/fimmu.2022.995412

N/A

0.442DataRank · unranked

18 citations

Fiachra Humphries, Roxie C. Girardin, Aaron Wallace, Monir Ejemel, Alla Amcheslavsky +17 more

Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development

Viruses(2021)10.3390/v13061027

N/A

0.360DataRank · unranked

10 citations

Andrezza Campos Chagas, Brian G. Pierce, Thomas R. Fuerst, Eric A. Toth

Evaluation of AlphaFold modeling for elucidation of nanobody–peptide epitope interactions

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110268

N/A

0.324DataRank · unranked

6 citations

Swarnali Roy, Shubhra Jyoti Saha, Gengxiang Zhao, Rashmi Kumariya, Brendan A. Creemer +5 more

T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes

Genes(2021)10.3390/genes12060852

N/A

0.312DataRank · unranked

7 citations

Laura Cort, Zhijun Liu, Ryan Eberwine, Elizabeth P. Blankenhorn, Brian G. Pierce +1 more

Exploring the potential of structure-based deep learning approaches for T cell receptor design

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012489

N/A

0.269DataRank · unranked

5 citations

Gabriel Ernesto Jara, João Victor da Silva Guerra, Melyssa Cheung, Nathaniel Felbinger, José Geraldo de Carvalho Pereira +3 more

Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers

Communications Biology(2025)10.1038/s42003-025-08239-w

N/A

0.241DataRank · unranked

4 citations

S.S. Karade, S. Saif Hasan, Rui Yin, Liqun Jiang, Yanxin Liu +9 more

Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

Preprints.org(2024)10.20944/preprints202403.1439.v1

N/A

0.208DataRank · unranked

3 citations

Nathaniel Felbinger, Mathew Metcalf, Eric A. Toth, Gilad Ofek, Thomas R. Fuerst +1 more

CoV3D: A database and resource for high resolution coronavirus protein structures

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.12.091983

Top 71%

0.133DataRank

Top 71%1 citations

Johnathan D. Guest, Rui Yin, Jared Adolf-Bryfogle, William R. Schief, Brian G. Pierce +1 more

RNA Helicase DDX3 Interacts with the Capsid Protein of Hepatitis E Virus and Plays a Vital Role in the Viral Replication

Pathogens(2025)10.3390/pathogens14020177

N/A

0.104DataRank · unranked

1 citations

Bhargava Teja Sallapalli, Peixi Chang, Jia He, Étienne Coyaud, Brian G. Pierce +2 more

Structural basis for recognition of two HLA-A2-restricted SARS-CoV-2 spike epitopes by public and private T cell receptors

Research Square(2021)10.21203/rs.3.rs-726298/v1

N/A

0.104DataRank · unranked

1 citations

A. V. Kolesnikov, Rui Yin, Johnathan D. Guest, Ragul Gowthaman, Anton Shmelev +5 more

SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors

Nature Communications(2023)10.1038/s41467-023-42430-z

N/A

0DataRank · unranked

18 citations

Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lü, Daichao Wu +33 more

A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs

Nature Communications(2023)10.1038/s41467-023-44076-3

N/A

0DataRank · unranked

16 citations

Enya Qing, Yanan He, Yihong Chen, Benjamin C. Jennings, Whitaker Cohn +10 more

Evaluation of AlphaFold Antibody-Antigen Modeling with Implications for Improving Predictive Accuracy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.05.547832

N/A

0DataRank · unranked

25 citations

Brian G. Pierce, Rui Yin

Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

Viruses(2024)10.3390/v16050803

N/A

0DataRank · unranked

14 citations

Nathaniel Felbinger, Matthew C. Metcalf, Eric A. Toth, Gilad Ofek, Thomas R. Fuerst +1 more

Proscan: a structure-based proline design web server

Nucleic Acids Research(2024)10.1093/nar/gkae408

N/A

0DataRank · unranked

6 citations

Helder Veras Ribeiro Filho, Brian G. Pierce, Nathaniel Felbinger

Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers

Science Advances(2024)10.1126/sciadv.adk8157

N/A

0DataRank · unranked

2 citations

Jonathan J. Du, Maria W. Flowers, Athir Farhan Ali, Jeremy C. Hunn, Nina Vijayvargiya +9 more

A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

Structure(2025)10.1016/j.str.2025.04.016

N/A

0DataRank · unranked

5 citations

Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani, Christine C. Siska, Rutilio H. Clark, Woo Chi +41 more

Structural insights into clonal restriction and diversity in T cell recognition of two immunodominant SARS-CoV-2 nucleocapsid epitopes

Nature Communications(2025)10.1038/s41467-025-66322-6

N/A

0DataRank · unranked

2 citations

Guodong Chen, Yukun Li, Xichun Liu, Shayana Saravanakumar, Jianfeng Zhao +9 more

AlphaFold and Docking Approaches for Antibody–Antigen and Other Targets: Insights From CAPRI Rounds 47–55

Proteins Structure Function and Bioinformatics(2025)10.1002/prot.26801

N/A

0DataRank · unranked

3 citations

Minjae Park, Rui Yin, Johnathan D. Guest, Brian G. Pierce, Ragul Gowthaman

Dynamic S -acylation of GSDMA regulates pyroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.16.682910

N/A

0DataRank · unranked

0 citations

Ritesh Thakare, Melyssa Cheung, Jianan Zhang, Xin Chen, Xiaodi Hu +4 more

Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas

Nature Communications(2020)10.1038/s41467-020-15572-7

N/A

0DataRank · unranked

100 citations

Peter Doukas, Maria E. Martínez Escala, Kimberly G. Ringbloom, David Shih, Jingyi Yang +19 more

Engineering HIV antibodies with enhanced breadth and potency of neutralization through multistate affinity maturation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.22.684031

N/A

0DataRank · unranked

0 citations

Swastik Phulera, Monica L. Fernández‐Quintero, Johannes R. Loeffler, Collin Joyce, Jordan L. Woehl +26 more

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

Nature Communications(2020)10.1038/s41467-020-16755-y

N/A

0DataRank · unranked

78 citations

D. Travis Gallagher, Ragul Gowthaman, Brian G. Pierce, Roy A. Mariuzza, Daichao Wu

High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides

Bioinformatics(2020)10.1093/bioinformatics/btaa1050

N/A

0DataRank · unranked

22 citations

Brian G. Pierce, Thom Vreven, Brian M. Baker, Zhiping Weng, Tyler Borrman

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.044073

N/A

0DataRank · unranked

3 citations

Zhen–Yong Keck, Ruixue Wang, Patrick Lau, Kyle Garagusi, Khadija Elkholy +12 more

RNA Helicase DDX3 Interacts with the Capsid Protein of Hepatitis E Virus and Plays an Indispensable Role in the Viral Replication

Preprints.org(2020)10.20944/preprints202012.0557.v1

N/A

0DataRank · unranked

3 citations

Peixi Chang, Jia He, Étienne Coyaud, Brian G. Pierce, Yan‐Jin Zhang +1 more

Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

UNC Libraries(2020)10.17615/35z7-9284

N/A

0DataRank · unranked

0 citations

Thom Vreven, Şefik Kerem Ovalı, Jacob E. Corn, Eva‐Maria Strauch, Julie C. Mitchell +27 more

An expanded benchmark for antibody-antigen docking and affinity prediction reveals insights into antibody recognition determinants

Structure(2021)10.1016/j.str.2021.01.005

N/A

0DataRank · unranked

125 citations

Thom Vreven, Jing Zhou, Iain H. Moal, Jeliazko R. Jeliazkov, Jeffrey J. Gray +3 more

An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development

Gastroenterology(2021)10.1053/j.gastro.2021.10.005

N/A

0DataRank · unranked

43 citations

Richard A. Urbanowicz, Johnathan D. Guest, Nicole Frumento, Alexis Figueroa, Kaitlyn E. Clark +14 more

Structural and energetic profiling of SARS-CoV-2 receptor binding domain antibody recognition and the impact of circulating variants

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009380

N/A

0DataRank · unranked

16 citations

Johnathan D. Guest, Ghazaleh Taherzadeh, Ragul Gowthaman, Ipsa Mittra, Jane Quackenbush +2 more

Benchmarking AlphaFold for protein complex modeling reveals accuracy determinants

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.23.465575

N/A

0DataRank · unranked

25 citations

Brandon Y. Feng, Amitabh Varshney, Brian G. Pierce, Rui Yin

An Extended Motif in the SARS-CoV-2 Spike Modulates Binding and Release of Host Coatomer in Retrograde Trafficking

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.03.458953

N/A

0DataRank · unranked

2 citations

Suruchi Singh, S. Khan, Matthew F. Martin, Nicholas Schnicker, Lokesh Gakhar +3 more

Structural basis for recognition of two HLA-A2-restricted SARS-CoV-2 spike epitopes by public and private T cell receptors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.28.454232

N/A

0DataRank · unranked

2 citations

A. V. Kolesnikov, Rui Yin, Johnathan D. Guest, Ragul Gowthaman, Anton Shmelev +5 more

Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors

Nature Communications(2022)10.1038/s41467-021-27669-8

N/A

0DataRank · unranked

45 citations

A. V. Kolesnikov, Rui Yin, Johnathan D. Guest, Ragul Gowthaman, Anton Shmelev +6 more

An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking

Communications Biology(2022)10.1038/s42003-022-03063-y

N/A

0DataRank · unranked

26 citations

Suruchi Singh, S. Khan, Matthew F. Martin, Nicholas Schnicker, Lokesh Gakhar +3 more

Evaluation of AlphaFold antibody–antigen modeling with implications for improving predictive accuracy

Protein Science(2023)10.1002/pro.4865

N/A

0DataRank · unranked

132 citations

Brian G. Pierce, Rui Yin

TCRmodel2: high-resolution modeling of T cell receptor recognition using deep learning

Nucleic Acids Research(2023)10.1093/nar/gkad356

N/A

0DataRank · unranked

107 citations

Helder Veras Ribeiro Filho, Valerie C. L. Lin, Ragul Gowthaman, Melyssa Cheung, Brian G. Pierce +1 more

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Nature Communications(2023)10.1038/s41467-023-39659-z

N/A

0DataRank · unranked

34 citations

Benjamin M. Janus, Rui Yin, Ruixue Wang, Johnathan D. Guest, Edwin Pozharski +7 more

Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity

Frontiers in Immunology(2023)10.3389/fimmu.2023.1303304

N/A

0DataRank · unranked

25 citations

Daichao Wu, Brian G. Pierce, Roy A. Mariuzza

Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor diversity

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103035

N/A

0DataRank · unranked

20 citations

Grigory A. Efimov, A. V. Bogolyubova, Brian G. Pierce, Roy A. Mariuzza, Daichao Wu

Brian G. Pierce

Indexed papers

Top data-sharing exemplar

Papers