🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Irene T. Weber

Ruhr University Bochum

ORCID: 0000-0003-4876-7393
MedicineImmunology and MicrobiologyMaterials ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 13 papers. Top paper: “Narrow Substrate Specificity and Sensitivity toward Ligand-binding Site Mutations of Human T-cell Leukemia Virus Type 1 Protease”.

Narrow Substrate Specificity and Sensitivity toward Ligand-binding Site Mutations of Human T-cell Leukemia Virus Type 1 Protease

Journal of Biological Chemistry(2004)10.1074/jbc.m401868200
N/A
0.584DataRank · unranked
48 citations

Irene T. Weber, Péter Bagossi, Gabriella Miklóssy, Péter Boross, Stephen Oroszlan +2 more

Proton transfer and drug binding details revealed in neutron diffraction studies of wild-type and drug resistant HIV-1 protease

Methods in enzymology on CD-ROM/Methods in enzymology(2020)10.1016/bs.mie.2019.12.002
N/A
0DataRank · unranked
7 citations

Oksana Gerlits, Kaira Beltran, Kevin L. Weiss, David A. Keen, Matthew P. Blakeley +3 more

HIV Protease: Historical Perspective and Current Research

Viruses(2021)10.3390/v13050839
N/A
0DataRank · unranked
98 citations

Yuan‐Fang Wang, Robert W. Harrison, Irene T. Weber

Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PRS17

Biochemical and Biophysical Research Communications(2021)10.1016/j.bbrc.2021.05.094
N/A
0DataRank · unranked
8 citations

Daniel W. Kneller, Arun K. Ghosh, Irene T. Weber, Johnson Agniswamy

Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17

Journal of Molecular Graphics and Modelling(2021)10.1016/j.jmgm.2021.108005
N/A
0DataRank · unranked
3 citations

Daniel W. Kneller, Yuan‐Fang Wang, Andrey Kovalevsky, Irene T. Weber, S.H. Burnaman

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase

Archives of Biochemistry and Biophysics(2021)10.1016/j.abb.2021.109100
N/A
0DataRank · unranked
2 citations

Renata A.G. Reis, Johnson Agniswamy, Irene T. Weber, Giovanni Gadda, Archana Iyer

Evolution of drug resistance in HIV protease

BMC Bioinformatics(2020)10.1186/s12859-020-03825-7
N/A
0DataRank · unranked
32 citations

Christopher B. Freas, Irene T. Weber, Robert W. Harrison, Dhara Shah

Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands

ChemMedChem(2022)10.1002/cmdc.202200058
N/A
0DataRank · unranked
6 citations

Satish Kovela, Ashish Sharma, Dana Shahabi, Ajay K. Ghosh, Denver R. Hopkins +11 more

HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics

Journal of Molecular Graphics and Modelling(2022)10.1016/j.jmgm.2022.108315
N/A
0DataRank · unranked
6 citations

Yuan-Fang Wang, Daniel W. Kneller, Andrey Kovalevsky, Arun K. Ghosh, Robert W. Harrison +2 more

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129168
N/A
0DataRank · unranked
8 citations

Dana Shahabi, Maya Kipfmiller, Ajay K. Ghosh, Megan Johnson, Yuan-Fang Wang +5 more

Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115385
N/A
0DataRank · unranked
5 citations

Jennifer L. Mishevich, Satish Kovela, Ryan Shaktah, Ajay K. Ghosh, Megan Johnson +9 more

Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies

Organic & Biomolecular Chemistry(2024)10.1039/d4ob00506f
N/A
0DataRank · unranked
2 citations

Daniel Lee, Ashish Sharma, Megan Johnson, Ajay K. Ghosh, Yuan-Fang Wang +6 more

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Chemical Communications(2022)10.1039/d2cc04541a
N/A
0DataRank · unranked
24 citations

Irene T. Weber, Hiroaki Mitsuya, Arun K. Ghosh