Christine E. Brown

Also affiliated with City of Hope, Beckman Research Institute

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 47 papers. Top paper: “Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial”.

Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial

Nature Medicine(2024)10.1038/s41591-024-02875-1

N/A

3.8DataRank · unranked

308 citations

Jonathan Hibbard, Darya Alizadeh, M. Suzette Blanchard, Heini M. Natri, Dongrui Wang +25 more

Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma

Neuro-Oncology(2022)10.1093/neuonc/noac024

N/A

3.2DataRank · unranked

145 citations

Analiz Rodriguez, Joycelynne Palmer, Julie R. Ostberg, Araceli Naranjo, Jamie R. Wagner +18 more

CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

Cancer Discovery(2020)10.1158/2159-8290.cd-20-1243

N/A

0.784DataRank · unranked

185 citations

Briana C. Prager, Ryan C. Gimple, Brenda Aguilar, Darya Alizadeh, Hongzhen Tang +14 more

Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2020-002181

N/A

0.713DataRank · unranked

115 citations

Edbert D Lu, O. Badillo, Shokoufeh Karimi, Eric V Liu, Whitney Tamaki +19 more

Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression

Nature Communications(2022)10.1038/s41467-022-31340-1

N/A

0.706DataRank · unranked

110 citations

Syed Mohd Faisal, Patrick Dunn, Anna E. Argento, Todd Hollon, Wajd N. Al‐Holou +13 more

Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables

Frontiers in Immunology(2023)10.3389/fimmu.2023.1115536

N/A

0.529DataRank · unranked

33 citations

Agata Xella, Ryan T. Woodall, Vikram Adhikarla, Heyrim Cho, Margarita Gutova +3 more

Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma

Neoplasia(2022)10.1016/j.neo.2022.100801

N/A

0.483DataRank · unranked

24 citations

Lihong Weng, Dina Awabdeh, Yubo Zhai, Renate Starr, Massimo D’Apuzzo +6 more

Modeling interaction of Glioma cells and CAR T-cells considering multiple CAR T-cells bindings

ImmunoInformatics(2023)10.1016/j.immuno.2023.100022

N/A

0.457DataRank · unranked

20 citations

Prativa Sahoo, Dongrui Wang, Qixuan Wang, Christine E. Brown, Russell C. Rockne +2 more

Expansion of endogenous T cells in CSF of pediatric CNS tumor patients undergoing locoregional delivery of IL13R⍺2-targeting CAR T cells: an interim analysis

Research Square(2023)10.21203/rs.3.rs-3454977/v1

N/A

0.425DataRank · unranked

16 citations

Angela Taravella Oill, M.J. Blanchard, Melody Wu, Jonathan Hibbard, Sean Sepulveda +30 more

Antibody-based redirection of universal Fabrack-CAR T cells selectively kill antigen bearing tumor cells

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2021-003752

N/A

0.345DataRank · unranked

9 citations

Cheng-Fu Kuo, Kurt J. Jenkins, Alfur Fu-Hsin Hung, Wen-Chung Chang, Miso Park +6 more

Structural and practical identifiability of contrast transport models for DCE-MRI

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012106

N/A

0.330DataRank · unranked

8 citations

Ryan T. Woodall, Margarita Gutova, Bihong T. Chen, Mark S. Shiroishi, Christine E. Brown +3 more

CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.23.634499

N/A

0.292DataRank · unranked

6 citations

Agata Xella, Ryan T. Woodall, Kevin A. Cassady, Sergio Branciamore, Christine E. Brown +2 more

Overcoming myeloid-driven resistance to CAR T therapy by targeting SPP1

10.1101/2025.04.01.646202

N/A

0.269DataRank · unranked

5 citations

Heini M. Natri, Yuqi Zhao, Shengchao Xu, Maryam Aftabizadeh, Begonya Comin-Anduix +18 more

Label-free in-line characterization of immune cell culture using quantitative phase imaging

npj Regenerative Medicine(2025)10.1038/s41536-025-00442-x

N/A

0.208DataRank · unranked

3 citations

Viswanath Gorti, Paloma Casteleiro Costa, Aaron D. Silva Trenkle, Bharat Kanwar, Bryan Wang +14 more

Chlorotoxin Redirects Chimeric Antigen Receptor T Cells for Specific and Effective Targeting of Glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.24.918888

N/A

0.165DataRank · unranked

2 citations

Renate Starr, Wen-Chung Chang, Brenda Aguilar, Darya Alizadeh, Sarah Wright +12 more

Phase I Trial Evaluating Locoregionally-delivered IL13Rα2-targeting CAR T Cells in High-Grade Glioma

Research Square(2023)10.21203/rs.3.rs-3117663/v1

N/A

0.104DataRank · unranked

1 citations

Jonathan Hibbard, Darya Alizadeh, M.J. Blanchard, Heini M. Natri, Dongrui Wang +21 more

Favorable Activity and Safety Profile of Memory-Enriched CD19-Targeted Chimeric Antigen Receptor T-Cell Therapy in Adults with High-Risk Relapsed/Refractory ALL

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-2038

N/A

0DataRank · unranked

57 citations

Samer K. Khaled, Xiuli Wang, Joycelynne Palmer, Yan Wang, Jamie R. Wagner +17 more

Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapy

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2112006119

N/A

0DataRank · unranked

26 citations

Sharareh Gholamin, Ignacio Moraga, Xin Yang, Supraja Saravanakumar, Joseph R. Cohen +10 more

Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy

PLoS Computational Biology(2022)10.1371/journal.pcbi.1009504

N/A

0DataRank · unranked

23 citations

Xin Yang, Eric Ma, Margarita Gutova, Christine E. Brown, Russell C. Rockne +1 more

Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.01.462697

N/A

0DataRank · unranked

2 citations

Xin Yang, Eric Ma, Margarita Gutova, Christine E. Brown, Russell C. Rockne +1 more

Loss of SIRT1 inhibits hematopoietic stem cell aging and age-dependent mixed phenotype acute leukemia

Communications Biology(2022)10.1038/s42003-022-03340-w

N/A

0DataRank · unranked

18 citations

Chunxiao Zhang, Charles Warden, Zheng Liu, Yate‐Ching Yuan, Chao Guo +12 more

Inclusion of 4-1BB Costimulation Enhances Selectivity and Functionality of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells

Cancer Research Communications(2022)10.1158/2767-9764.crc-22-0185

N/A

0DataRank · unranked

12 citations

Brenda Aguilar, Diana Gumber, Madeleine Maker, Stephanie M. Huard, Dongrui Wang +10 more

CAR T cell therapy drives endogenous locoregional T cell dynamics in a responding patient with glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.460392

N/A

0DataRank · unranked

6 citations

Raymond T. Ng, Natalie Dullerud, Robyn A. Wong, Jonathan Hibbard, Dongrui Wang +8 more

A phase 1 study to evaluate chimeric antigen receptor (CAR) T cells incorporating a chlorotoxin tumor-targeting domain for patients with MMP2+ Recurrent or progressive glioblastoma (NCT04214392).

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.tps2662

N/A

0DataRank · unranked

9 citations

Michael E. Barish, Ammar Chaudhry, Massimo D’Apuzzo, Stephen J. Forman, Jana Portnow +10 more

Repeatability of tumor perfusion kinetics from dynamic contrast-enhanced MRI in glioblastoma

Neuro-Oncology Advances(2021)10.1093/noajnl/vdab174

N/A

0DataRank · unranked

12 citations

Prativa Sahoo, Yujie Cui, Bihong T. Chen, Mark S. Shiroishi, Cristina Lavini +6 more

Donor-derived CD19-targeted chimeric antigen receptor T cells in adult transplant recipients with relapsed/refractory acute lymphoblastic leukemia

Blood Cancer Journal(2023)10.1038/s41408-023-00881-z

N/A

0DataRank · unranked

4 citations

Samer K. Khaled, Yan Wang, Xiuli Wang, Joycelynne Palmer, Mary C. Clark +6 more

Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy

Frontiers in Immunology(2021)10.3389/fimmu.2021.635173

N/A

0DataRank · unranked

91 citations

Seigmund Wai Tsuen Lai, Christine E. Brown, Mingye Feng, Siqi Chen

Data from Recognition and Killing of Brain Tumor Stem-Like Initiating Cells by CD8+ Cytolytic T Cells

(2023)10.1158/0008-5472.c.6499980.v1

N/A

0DataRank · unranked

0 citations

Renate Starr, Catalina Martinez, Brenda Aguilar, Massimo D’Apuzzo, Иван Тодоров +6 more

Data from The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma

(2023)10.1158/2326-6066.c.6550309

N/A

0DataRank · unranked

0 citations

Christian Huynh, Ryan Urak, Lihong Weng, Miriam Walter, Laura Lim +21 more

Data from CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

(2023)10.1158/2159-8290.c.6549389.v1

N/A

0DataRank · unranked

0 citations

Briana C. Prager, Ryan C. Gimple, Brenda Aguilar, Darya Alizadeh, Hongzhen Tang +14 more

Data from The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma

(2023)10.1158/2326-6066.c.6550309.v1

N/A

0DataRank · unranked

0 citations

Christian Huynh, Ryan Urak, Lihong Weng, Miriam Walter, Laura Lim +21 more

Supplementary Table 2 from CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

INDIGO (University of Illinois at Chicago)(2023)10.1158/2159-8290.22540475.v1

N/A

0DataRank · unranked

0 citations

Briana C. Prager, Ryan C. Gimple, Brenda Aguilar, Darya Alizadeh, Hongzhen Tang +14 more

Structural and practical identifiability of contrast transport models for DCE-MRI

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.19.572294

N/A

0DataRank · unranked

0 citations

Ryan T. Woodall, Margarita Gutova, Bihong T. Chen, Mark S. Shiroishi, Christine E. Brown +3 more

Spatiotemporal analysis of glioma heterogeneity reveals Col1A1 as an actionable target to disrupt tumor mesenchymal differentiation, invasion and malignancy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.404970

N/A

0DataRank · unranked

2 citations

Syed Mohd Faisal, Patrick Dunn, Anna E. Argento, Todd Hollon, Wajd N. Al‐Holou +13 more

Targeting Wnt signaling for improved glioma immunotherapy

Frontiers in Immunology(2024)10.3389/fimmu.2024.1342625

N/A

0DataRank · unranked

19 citations

Jonathan Hibbard, Eric Ma, Heini M. Natri, Vikram Adhikarla, Nyam‐Osor Chimge +13 more

Systemic Anti–PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid

JAMA Oncology(2020)10.1001/jamaoncol.2020.4508

N/A

0DataRank · unranked

45 citations

Dongrui Wang, M. Suzette Blanchard, Vivi Tran, Darya Alizadeh, Renate Starr +10 more

CAR macrophages with built-In CD47 blocker combat tumor antigen heterogeneity and activate T cells via cross-presentation

Nature Communications(2025)10.1038/s41467-025-59326-9

N/A

0DataRank · unranked

37 citations

Yingyu Wang, Jessica Dang, Nuozi Song, X Chen, Jinhui Wang +7 more

Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence

Cancer Cell(2025)10.1016/j.ccell.2025.11.006

N/A

0DataRank · unranked

19 citations

Benjamin Oberlton, Mikaela Ribi, Ke Xuan Leow, Jolene S. Ranek, Inna Averbukh +35 more

Multimodal glioma immunotherapy combining TLR9-targeted STAT3 antisense oligodeoxynucleotides with PD1 immune checkpoint blockade

Neuro-Oncology(2025)10.1093/neuonc/noaf099

N/A

0DataRank · unranked

15 citations

Elaine Kang, Karol Jacek, Chunsong Yu, Xiaowei Zhang, Yicheng Zhu +10 more

Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102302

N/A

0DataRank · unranked

7 citations

Maryam Aftabizadeh, Jonathan Hibbard, M. Suzette Blanchard, Julie R. Ostberg, Jamie R. Wagner +15 more

CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma

Mathematical Biosciences(2025)10.1016/j.mbs.2025.109531

N/A

0DataRank · unranked

3 citations

Agata Xella, Ryan T. Woodall, Kevin A. Cassady, Sergio Branciamore, Christine E. Brown +2 more

The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma

Cancer Immunology Research(2020)10.1158/2326-6066.cir-20-0236

N/A

0DataRank · unranked

46 citations

Christian Huynh, Ryan Urak, Lihong Weng, Miriam Walter, Laura Lim +21 more

Chimeric Antigen Receptor T-Cell Therapy: Updates in Glioblastoma Treatment

Neurosurgery(2020)10.1093/neuros/nyaa584

N/A

0DataRank · unranked

17 citations

Christine E. Brown, Behnam Badie, Lisa Feldman

Whole-Proteome Screening and Multi-Modal Profiling of Antigen-Specific CD4+ T Cells at Single-Cell Resolution

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.21.649828

N/A

0DataRank · unranked

0 citations

Qi Jin, Michaela McKasson, Jongchan Choi, Vanessa Gutiérrez, Conor Brennan +35 more

Study of combination CAR T-cell treatment for glioblastoma using mathematical modeling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.04.657886

N/A

0DataRank · unranked

0 citations

Michael E. Barish, Margarita Gutova, Christine E. Brown, Russell C. Rockne, Heyrim Cho +1 more

3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells

Cell stem cell(2022)10.1016/j.stem.2022.02.009

N/A

0DataRank · unranked

139 citations

Helen P. McWilliams-Koeppen, Hernan Reza, Julie R. Ostberg, Wuyang Chen, Xiuli Wang +17 more

Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data

Journal of The Royal Society Interface(2020)10.1098/rsif.2019.0734

N/A

0DataRank · unranked

114 citations

Xin Yang, Daniel Abler, Davide Maestrini, Vikram Adhikarla, David Frankhouser +9 more