Markus Schirle

Also affiliated with Berkeley College, Novartis (China), Novartis (United States), Novartis (Ireland)

Biochemistry, Genetics and Molecular BiologyChemistryMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “Rational Chemical Design of Molecular Glue Degraders”.

Rational Chemical Design of Molecular Glue Degraders

ACS Central Science(2023)10.1021/acscentsci.2c01317

N/A

0.785DataRank · unranked

187 citations

James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Andreas O. Frank, Matthew J. Hesse +13 more

Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC

Cell chemical biology(2020)10.1016/j.chembiol.2020.09.001

N/A

0.764DataRank · unranked

162 citations

Alexander G. Cioffi, Felix C. Majewski, Jennifer Co, Nathaniel J. Henning, Michael D. Jones +6 more

Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB

(2023)10.1016/j.chembiol.2023.02.008

N/A

0.692DataRank · unranked

100 citations

Yoo Jin Cho, Nathan S. Hsu, Dustin Dovala, Jeffrey M. McKenna, John A. Tallarico +3 more

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

Journal of the American Chemical Society(2022)10.1021/jacs.2c04039

N/A

0.557DataRank · unranked

40 citations

Audrey G. Reeves, Annika C. S. Page, Patrick J. Moon, E. F. Miller, Katia Coulonval +17 more

Chemoproteomics-Enabled Discovery of a Covalent Molecular Glue Degrader Targeting NF-κB

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.18.492542

N/A

0.385DataRank · unranked

12 citations

Yoo Jin Cho, Dustin Dovala, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

Targeted Protein Degradation via a Covalent Reversible Degrader Based on Bardoxolone

ChemRxiv(2020)10.26434/chemrxiv.12055935.v1

N/A

0.373DataRank · unranked

11 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Angewandte Chemie International Edition(2025)10.1002/anie.202508518

N/A

0.360DataRank · unranked

10 citations

Kelvin Li, Christian E. Stieger, Erin L. Li, Brynne Currier, Scott M. Brittain +10 more

Targeted Protein Degradation through E2 Recruitment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.19.520812

N/A

0.312DataRank · unranked

7 citations

Dustin Dovala, Matthew J. Hesse, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.09.531918

N/A

0.241DataRank · unranked

4 citations

Danny Q. Thach, Yangzhi Wang, Belen E. Altamirano Poblano, Dustin Dovala, John A. Tallarico +5 more

Deubiquitinase-targeting chimeras for targeted protein stabilization

Nature Chemical Biology(2022)10.1038/s41589-022-00971-2

N/A

0DataRank · unranked

323 citations

Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Gang Liu, Erika Zhang +19 more

Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

Journal of the American Chemical Society(2022)10.1021/jacs.1c03980

N/A

0DataRank · unranked

214 citations

Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Erika Zhang, Jeffrey M. McKenna +5 more

PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer

Cell Death and Disease(2022)10.1038/s41419-021-04495-w

N/A

0DataRank · unranked

32 citations

Alexandria N. Young, Andrew C. Huntsman, Melissa R. Pergande, Melissa A. Korkmaz, Rathnayake A. Rathnayake +13 more

Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design

Chemical Science(2022)10.1039/d2sc00426g

N/A

0DataRank · unranked

31 citations

Spencer O. Scholz, Katherine E. Near, Jessica N. Spradlin, Bridget P. Belcher, Scott M. Brittain +6 more

Rational Chemical Design of Molecular Glue Degraders

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.04.512693

N/A

0DataRank · unranked

9 citations

James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Lynn M. McGregor, Matthew J. Hesse +5 more

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

ChemRxiv(2022)10.26434/chemrxiv-2022-9p94z

N/A

0DataRank · unranked

2 citations

Angel Gonzalez-Valero, Patrick J. Moon, Edward Y. Miller, Katia Coulonval, Steven W. M. Crossley +16 more

Activation of human STING by a molecular glue-like compound

Nature Chemical Biology(2023)10.1038/s41589-023-01434-y

N/A

0DataRank · unranked

72 citations

Stephen M. Canham, Hua Wu, Martin Hénault, Lihao Chen, Guoxun Liu +30 more

Targeted Protein Degradation through E2 Recruitment

ACS Chemical Biology(2023)10.1021/acschembio.3c00040

N/A

0DataRank · unranked

56 citations

Dustin Dovala, Matthew J. Hesse, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells

ACS Chemical Biology(2024)10.1021/acschembio.4c00064

N/A

0DataRank · unranked

9 citations

Danny Q. Thach, Zhouyang Zhu, Yangzhi Wang, Belen E. Altamirano Poblano, Dustin Dovala +6 more

Light‐Activated Reactivity of Nitrones with Amino Acids and Proteins

Angewandte Chemie International Edition(2024)10.1002/anie.202415976

N/A

0DataRank · unranked

4 citations

Maximilian Iglhaut, Qian Shao, F. García, Bo‐Yang Huang, Scott M. Brittain +5 more

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Angewandte Chemie(2025)10.1002/ange.202508518

N/A

0DataRank · unranked

0 citations

Kelvin Li, Christian E. Stieger, Erin L. Li, Brynne Currier, Scott M. Brittain +10 more

Bardoxolone conjugation enables targeted protein degradation of BRD4

Scientific Reports(2020)10.1038/s41598-020-72491-9

N/A

0DataRank · unranked

140 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Manumycin polyketides act as molecular glues between UBR7 and P53

Nature Chemical Biology(2020)10.1038/s41589-020-0557-2

N/A

0DataRank · unranked

134 citations

Mikiko Okumura, Lynn M. McGregor, Scott M. Brittain, Michael D. Jones, Xiaoyou Liang +8 more

A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.02.022541

N/A

0DataRank · unranked

12 citations

Jessica N. Spradlin, Luiz F. T. Novaes, Erika Zhang, Xirui Hu, Malte Moeller +8 more

Targeted Protein Degradation via a Covalent Reversible Degrader Based on Bardoxolone

ChemRxiv(2020)10.26434/chemrxiv.12055935

N/A

0DataRank · unranked

2 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Deubiquitinase-Targeting Chimeras for Targeted Protein Stabilization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.30.441959

N/A

0DataRank · unranked

32 citations

Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Bridget P. Belcher, Scott M. Brittain +8 more

Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.15.439993

N/A

0DataRank · unranked

22 citations

Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Jeffrey M. McKenna, John A. Tallarico +4 more

Donor-Acceptor Pyridinium Salts for Photo-Induced Electron Transfer Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes using Visible Light

Figshare(2021)10.33774/chemrxiv-2021-r2nd2

N/A

0DataRank · unranked

3 citations

Francisco Serradilla, Akash Mamon Sarkar, Nicholas Kuehl, David T. Barkan, Nicole Collins +5 more

Donor-Acceptor Pyridinium Salts for Photo-Induced Electron Transfer Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes using Visible Light

ChemRxiv(2021)10.26434/chemrxiv-2021-r2nd2

N/A

0DataRank · unranked

2 citations

Francisco Serradilla, Akash Mamon Sarkar, Nicholas Kuehl, David T. Barkan, Nicole Collins +5 more