Larry J. Friedman

Also affiliated with Massachusetts Institute of Technology, Brandeis University

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7”.

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

eLife(2021)10.7554/elife.65471

N/A

0.561DataRank · unranked

41 citations

Larry J. Friedman, Marko Lõoke, Christian Ramsoomair, Jeff Gelles, Stephen P. Bell +1 more

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221484120

N/A

0.457DataRank · unranked

20 citations

Shalini Gupta, Larry J. Friedman, Jeff Gelles, Stephen P. Bell, Audra L. Amasino

Single-molecule analysis of transcription activation: dynamics of SAGA co-activator recruitment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.07.552353

N/A

0.208DataRank · unranked

3 citations

Larry J. Friedman, Hogyu David Seo, Oluwatobi A. Adeleke, Bria Graham, Emily F Patteson +3 more

Changing protein-DNA interactions promote ORC binding site exchange during replication origin licensing

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.16.545300

N/A

0.165DataRank · unranked

2 citations

Larry J. Friedman, Jeff Gelles, Stephen P. Bell, Annie Zhang

A Helicase-tethered ORC Flip Enables Bidirectional Helicase Loading

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.06.463322

N/A

0DataRank · unranked

3 citations

Larry J. Friedman, Jeff Gelles, Stephen P. Bell, Shalini Gupta

Single molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.20.449130

N/A

0DataRank · unranked

2 citations

Larry J. Friedman, Jeff Gelles, Stephen Buratowski, Inwha Baek

Single‐Molecule Analysis of in vivo DNA Replication Origin Licensing Stoichiometry

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5092

N/A

0DataRank · unranked

0 citations

Johnson Chung, Larry J. Friedman, Jeff Gelles, Nick Rhind

Changing protein–DNA interactions promote ORC binding-site exchange during replication origin licensing

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2305556120

N/A

0DataRank · unranked

15 citations

Larry J. Friedman, Jeff Gelles, Stephen P. Bell, Annie Zhang

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.02.522488

N/A

0DataRank · unranked

3 citations

Shalini Gupta, Larry J. Friedman, Jeff Gelles, Stephen P. Bell, Audra Amasino

A mechanism of synergistic Mediator recruitment in RNA polymerase II transcription activation revealed by single-molecule fluorescence

Molecular Cell(2025)10.1016/j.molcel.2025.10.009

N/A

0DataRank · unranked

3 citations

Jongcheol Jeon, Nida Farheen, Larry J. Friedman, Jané Kondev, Stephen Buratowski +2 more

Single-molecule analysis of transcription activation: dynamics of SAGA coactivator recruitment

Nature Structural & Molecular Biology(2025)10.1038/s41594-024-01451-y

N/A

0DataRank · unranked

4 citations

Larry J. Friedman, Daniel J. Zhou, Hogyu David Seo, Oluwatobi A. Adeleke, Bria Graham +4 more

Mechanism of client loading from BiP to Grp94 and its disruption by select inhibitors

Nature Communications(2025)10.1038/s41467-025-58658-w

N/A

0DataRank · unranked

2 citations

Jiaqi Han, Erin E. Deans, Bin Huang, Reyal S. Hoxie, Larry J. Friedman +3 more

An Orc6 tether mediates ORC binding-site switching during replication origin licensing

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2510685122

N/A

0DataRank · unranked

2 citations

Larry J. Friedman, Jeff Gelles, Stephen P. Bell, D. D. Driscoll

Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.01.127969

N/A

0DataRank · unranked

4 citations

Inwha Baek, Larry J. Friedman, Yoo Jin Joo, Stephen Buratowski, Jeff Gelles +1 more

An Orc6 tether mediates ORC binding site switching during replication origin licensing

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.09.652650

N/A

0DataRank · unranked

1 citations

Larry J. Friedman, Jeff Gelles, Stephen P. Bell, D. D. Driscoll

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.09.417428

N/A

0DataRank · unranked

2 citations

Larry J. Friedman, Christian Ramsoomair, Jeff Gelles, Stephen P. Bell, Lorraine De Jesús-Kim

Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes

Molecular Cell(2021)10.1016/j.molcel.2021.07.025

N/A

0DataRank · unranked

64 citations

Larry J. Friedman, Jeff Gelles, Stephen Buratowski, Inwha Baek

Bayesian machine learning analysis of single-molecule fluorescence colocalization images

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.30.462536

N/A

0DataRank · unranked

3 citations

Larry J. Friedman, Jeff Gelles, Douglas L. Theobald, Yerdos Ordabayev