Shainnel O. Eans

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity”.

Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.9b01924

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0DataRank · unranked

48 citations

Ariana C. Brice‐Tutt, Shainnel O. Eans, Heather M. Stacy, Guqin Shi, Ranjala Ratnayake +7 more

Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

Molecules(2020)10.3390/molecules25173999

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19 citations

Sanjeewa N. Senadheera, Michelle L. Ganno, Shainnel O. Eans, Tanvir Khaliq, Thomas F. Murray +3 more

Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide cyclo[Pro-Sar-Phe-d-Phe]: A Mixed Opioid Receptor Agonist–Antagonist Following Oral Administration

ACS Chemical Neuroscience(2020)10.1021/acschemneuro.0c00086

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19 citations

Ariana C. Brice‐Tutt, Jeremy S. Coleman, Grant G. Simpson, Lisa Wilson, Shainnel O. Eans +5 more

A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01273

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0DataRank · unranked

75 citations

Jeffrey F. DiBerto, Abdelfattah Faouzi, Sarah M. Bernhard, Anna M. Gutridge, Steven Ramsey +19 more

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

eLife(2021)10.7554/elife.56519

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0DataRank · unranked

66 citations

Tao Che, Saheem A. Zaidi, Steven G. Grinnell, Balázs R. Varga, Abdelfattah Faouzi +19 more

Binge ethanol consumption-associated behavioral impairments in male mice using a gelatin-based drinking-in-the dark model

Alcohol(2021)10.1016/j.alcohol.2021.05.001

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7 citations

Jasmin Tawfic, Aziza Abrorkhujaeva, Sam Sowell, Sara Wu, Shainnel O. Eans +5 more

A novel mitragynine analog with low efficacy mu-opioid receptor agonism displays antinociception with attenuated adverse effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.22.440994

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6 citations

Jeffrey F. DiBerto, Abdelfattah Faouzi, Sarah M. Bernhard, Anna M. Gutridge, Steven Ramsey +19 more

Structure-based design of bitopic ligands for the µ-opioid receptor

Nature(2022)10.1038/s41586-022-05588-y

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0DataRank · unranked

128 citations

Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu +21 more

SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice

Neuropharmacology(2022)10.1016/j.neuropharm.2022.109239

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22 citations

Pamela M. Quizon, Yingying Wang, Charles Adeniran, Matthew J. Strauss, Ana Catya Jiménez-Torres +17 more

Solid-Phase Synthesis of the Bicyclic Peptide OL-CTOP Containing Two Disulfide Bridges, and an Assessment of Its In Vivo μ-Opioid Receptor Antagonism after Nasal Administration

Molecules(2023)10.3390/molecules28041822

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8 citations

Annika Tiller, Shahayra A. Majumder, Heather M. Stacy, Shainnel O. Eans, Aleksandra Nedovic +3 more

Tryptophan Substitution in CJ-15,208 (cyclo[Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Extinguished Cocaine-Conditioned Place Preference

Pharmaceuticals(2023)10.3390/ph16091218

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4 citations

Shainnel O. Eans, Jéssica Medina, Sanjeewa N. Senadheera, Tanvir Khaliq, Thomas F. Murray +3 more

SRI-30827, a novel allosteric modulator of the dopamine transporter, alleviates HIV-1 Tat-induced potentiation of cocaine conditioned place preference in mice

NeuroImmune Pharmacology and Therapeutics(2023)10.1515/nipt-2023-0022

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0 citations

Shainnel O. Eans, Thomas J. Cirino, Subramaniam Ananthan, Ana Catya Jiménez-Torres, Jun Zhu +2 more

Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR

ACS Central Science(2024)10.1021/acscentsci.4c00525

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0DataRank · unranked

13 citations

Nokomis Ramos‐Gonzalez, Qiongyu Li, Briana L. Sobecks, Deniz Aydın, Alexander S. Powers +14 more

Impact of HIV-1 tat protein on methamphetamine-induced inhibition of vesicular monoamine transporter2-mediated dopamine transport and methamphetamine conditioned place preference in HIV-1 tat transgenic mice

European Journal of Pharmacology(2024)10.1016/j.ejphar.2024.177030

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6 citations

Abagail Brenda Cirincione, Matthew J. Strauss, Sarah E. Davis, Shainnel O. Eans, Danielle K Tribbitt +3 more

Structure-Guided Design of Partial Agonists at an Opioid Receptor

Research Square(2024)10.21203/rs.3.rs-4664764/v1

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0DataRank · unranked

0 citations

Balázs R. Varga, Sarah M. Bernhard, Amal El Daibani, Saheem A. Zaidi, Jordy Homing Lam +12 more

Structure-guided design of partial agonists at an opioid receptor

Nature Communications(2025)10.1038/s41467-025-57734-5

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14 citations

Sarah M. Bernhard, Amal El Daibani, Saheem A. Zaidi, Jordy Homing Lam, Jhoan Aguilar +16 more

Total synthesis and biological activity of “carbamorphine”: O-to-CH 2 replacement in the E-ring of the morphine core structure

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2425438122

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3 citations

Rohini S. Ople, Alexander Kremsmair, Nokomis Ramos‐Gonzalez, Thomas Nedungadan, Brandon J. Kennedy +9 more

Synthesis and Pharmacology of a Morphinan-Derived Dual Mu–Kappa Opioid Receptor Agonist Analgesic

ACS Chemical Neuroscience(2025)10.1021/acschemneuro.5c00312

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2 citations

Rajendra Uprety, Barnali Paul, Alois Knoll, Nokomis Ramos‐Gonzalez, Kevin Appourchaux +26 more

Dual Opioid–Neuropeptide FF Small Molecule Ligands Demonstrate Analgesia with Reduced Tolerance Liabilities

Molecules(2025)10.3390/molecules30132851

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0DataRank · unranked

0 citations

V. Blair Journigan, Samuel Obeng, Victoria L.C. Pallares, Christophe Mѐsangeau, Coco N. Kapanda +12 more

Optimization of the Macrocyclic Tetrapeptide [D-Trp]CJ-15,208 to Prevent Stress-Induced Relapse of Cocaine-Seeking Behavior

Molecules(2025)10.3390/molecules30193993

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0DataRank · unranked

0 citations

Dmitry Yakovlev, Jeremy S. Coleman, Sanjeewa N. Senadheera, Heather M. Stacy, Shainnel O. Eans +4 more