T. Kendall Harden

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “Structure−Activity Relationships of Uridine 5‘-Diphosphate Analogues at the Human P2Y 6 Receptor”.

Structure−Activity Relationships of Uridine 5‘-Diphosphate Analogues at the Human P2Y 6 Receptor

UNC Libraries(2020)10.17615/tfjc-9573

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0DataRank · unranked

7 citations

Hyojin Ko, T. Kendall Harden, Pedro Besada, Gilles Gosselin, Savitri Maddileti +5 more

Aberrant Receptor Internalization and Enhanced FRS2-dependent Signaling Contribute to the Transforming Activity of the Fibroblast Growth Factor Receptor 2 IIIb C3 Isoform

UNC Libraries(2020)10.17615/zagr-k882

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0DataRank · unranked

5 citations

Channing J. Der, Y. Jiyoung, Savitri Maddileti, Natalia Mitin, T. Kendall Harden

Structure−Activity Relationship of Uridine 5‘ - Diphosphoglucose Analogues as Agonists of the Human P2Y 14 Receptor

UNC Libraries(2020)10.17615/xb5c-w853

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0DataRank · unranked

5 citations

Kenneth A. Jacobson, Hyojin Ko, Andrei A. Ivanov, T. Kendall Harden, Ingrid Fricks

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists

UNC Libraries(2020)10.17615/savq-8g88

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4 citations

Sonia de Castro, Mario Grifantini, Serge Van Calenbergh, T. Kendall Harden, Hyojin Ko +8 more

Human P2Y 6 Receptor: Molecular Modeling Leads to the Rational Design of a Novel Agonist Based on a Unique Conformational Preference

Figshare(2020)10.17615/c3bm-j883

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2 citations

Kenneth A. Jacobson, Víctor E. Márquez, Bhalchandra V. Joshi, Liaman Mamedova, Stefano Costanzi +3 more

Human P2Y 1 Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites

UNC Libraries(2020)10.17615/wq9x-z036

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0DataRank · unranked

2 citations

Emidio Camaioni, Stefano Moro, José L. Boyer, Kenneth A. Jacobson, Danping Guo +1 more

Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen

UNC Libraries(2020)10.17615/ev6p-yt94

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0DataRank · unranked

1 citations

John Sondek, Nicole Hajicek, Matthew O. Barrett, Qisheng Zhang, Stephanie C. Hicks +2 more

Functionalized Congeners of P2Y 1 Receptor Antagonists: 2-Alkynyl ( N )-Methanocarba 2′-Deoxyadenosine 3′,5′-Bisphosphate Analogues and Conjugation to a Polyamidoamine (PAMAM) Dendrimer Carrier

UNC Libraries(2020)10.17615/ked8-2s69

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0DataRank · unranked

1 citations

Stefano Costanzi, S. Michael Kilbey, T. Kendall Harden, Béatrice Hechler, Garth G. Brown +5 more

[ 32 P]2-iodo- N 6 -methyl-( N )-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([ 32 P]MRS2500), a novel radioligand for quantification of native P2Y 1 receptors

UNC Libraries(2020)10.17615/44e8-xn58

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1 citations

Dayle Houston, T. Kendall Harden, M. Ohno, Kenneth A. Jacobson, Robert A. Nicholas

Acireductone Dioxygenase 1 (ARD1) Is an Effector of the Heterotrimeric G Protein Subunit in Arabidopsis

UNC Libraries(2020)10.17615/d271-d660

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1 citations

Aditi Deshpande, Erin J. Friedman, Thomas C. Pochapsky, Helen X. Wang, Alan M. Jones +5 more

Enhanced Potency of Nucleotide−Dendrimer Conjugates as Agonists of the P2Y 14 Receptor: Multivalent Effect in G Protein-Coupled Receptor Recognition

Figshare(2020)10.17615/wtck-5m29

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1 citations

Kenneth A. Jacobson, Rhonda L. Carter, Andrei A. Ivanov, Arijit Das, T. Kendall Harden +1 more

The Role of Amino Acids in Extracellular Loops of the Human P2Y 1 Receptor in Surface Expression and Activation Processes

UNC Libraries(2020)10.17615/trtx-es56

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1 citations

Stefano Moro, T. Kendall Harden, Robert A. Nicholas, Kenneth A. Jacobson, Carsten Hoffmann

Ligand and structure-based methodologies for the prediction of the activity of G protein-coupled receptor ligands

UNC Libraries(2020)10.17615/bka0-qh43

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0 citations

Kenneth A. Jacobson, Stefano Costanzi, T. Kendall Harden, Irina G. Tikhonova

Ser352 and Ser354 in the carboxyl terminus of the human P2Y1 receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells: Phosphorylation and internalization of P2Y1 receptors

UNC Libraries(2020)10.17615/r2qs-6t42

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0DataRank · unranked

0 citations

Robert A. Nicholas, T. Kendall Harden, Dayle Houston‐Cohen, Ai Dong Qi, Isabella Naruszewicz

Molecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5′-diphosphoglucose

UNC Libraries(2020)10.17615/gcez-6m23

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0DataRank · unranked

0 citations

Hyojin Ko, Jan Hajduch, Andrei A. Ivanov, Artem Melman, Arijit Das +8 more

Structure of Gαi1 Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide Exchange

UNC Libraries(2020)10.17615/dy5d-v834

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0 citations

Mark R. Jezyk, David P. Siderovski, T. Kendall Harden, Francis S. Willard, Val J. Watts +7 more

UDP-glucose promotes neutrophil recruitment in the lung

UNC Libraries(2020)10.17615/qb3w-2y38

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0DataRank · unranked

0 citations

Juliana I. Sesma, Scott H. Donaldson, Alessandra Livraghi-Butrico, Hong Dang, Clarissa D. Weitzer +4 more

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

UNC Libraries(2020)10.17615/wx0p-ch21

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0DataRank · unranked

0 citations

Daeho Park, Scott F. Walk, Kodi S. Ravichandran, Norbert Leitinger, Marina Ostankovich +9 more

A comparison of calcium-activated potassium channel currents in cell- attached and excised patches

UNC Libraries(2020)10.17615/4y5x-rx38

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0DataRank · unranked

0 citations

Scott A. Oglesby, T. Kendall Harden, B S Pallotta, John R. Hepler

Quantification of recombinant and platelet P2Y1 receptors utilizing a [125I]-labeled high-affinity antagonist 2-iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([125I]MRS2500)

UNC Libraries(2020)10.17615/wkxc-5d94

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0DataRank · unranked

0 citations

Garth G. Brown, Christian Gachet, Sonia de Castro, Philippe Ohlmann, T. Kendall Harden +1 more

Crystal structure of the multifunctional Gβ5–RGS9 complex

UNC Libraries(2020)10.17615/y9kb-4m80

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0 citations

Svetlana Gershburg, Jason T. Snyder, Matthew L. Cheever, John Sondek, T. Kendall Harden +1 more

Evidence that the epidermal growth factor receptor and non-tyrosine kinase hormone receptors stimulate phosphoinositide hydrolysis by independent pathways

UNC Libraries(2020)10.17615/n8e1-cf59

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0 citations

RA Jeffs, H. Shelton Earp, SG Rhee, WR Huckle, JR Hepler +2 more

General and Versatile Autoinhibition of PLC Isozymes

UNC Libraries(2020)10.17615/24g1-3q92

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0 citations

Mark R. Jezyk, John Sondek, Svetlana Gershburg, Jason P. Seifert, T. Kendall Harden +1 more

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

UNC Libraries(2020)10.17615/a4jv-yy19

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0DataRank · unranked

0 citations

Savitri Maddileti, Adam Shutes, Rudolph L. Juliano, Channing J. Der, T. Kendall Harden +5 more

Synthesis and P2Y receptor activity of nucleoside 5′-phosphonate derivatives

UNC Libraries(2020)10.17615/3bdc-7914

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0DataRank · unranked

0 citations

T. Kendall Harden, Serge Van Calenbergh, Bhalchandra V. Joshi, Hyojin Ko, Liesbet Cosyn +2 more

Pyrimidine Ribonucleotides with Enhanced Selectivity as P2Y 6 Receptor Agonists: Novel 4-Alkyloxyimino, (S)-Methanocarba, and 5′-Triphosphate γ-Ester Modifications †

UNC Libraries(2020)10.17615/9vwt-ya70

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0 citations

Barkın Berk, Kenneth A. Jacobson, Рамачандран Баласубраманиан, Dilip K. Tosh, Hiroshi Maruoka +6 more

Dual Activation of Phospholipase C-ϵ by Rho and Ras GTPases

UNC Libraries(2020)10.17615/qh8z-ct27

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0 citations

Jason P. Seifert, Stephanie N. Hicks, Yixing Zhou, John Sondek, T. Kendall Harden

Fluorescent Phosphatidylinositol 4,5-Bisphosphate Derivatives with Modified 6-Hydroxy Group as Novel Substrates for Phospholipase C

INDIGO (University of Illinois at Chicago)(2020)10.17615/abyj-e230

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0DataRank · unranked

0 citations

Qisheng Zhang, Matthew O. Barrett, John Sondek, Xiaoyang Wang, T. Kendall Harden

Mechanism of Phosphorylation-induced Activation of Phospholipase C-γ Isozymes

UNC Libraries(2020)10.17615/xnkc-9f07

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0 citations

Aurélie Gresset, John Sondek, Stephanie N. Hicks, T. Kendall Harden

Membrane-induced Allosteric Control of Phospholipase C-β Isozymes

UNC Libraries(2020)10.17615/m9k7-j936

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0DataRank · unranked

0 citations

Matthew O. Barrett, John Sondek, T. Kendall Harden, Gary L. Waldo, Weigang Huang +2 more

Molecular Modeling of the Human P2Y2 Receptor and Design of a Selective Agonist, 2′-Amino-2′-deoxy-2-thio-UTP

UNC Libraries(2020)10.17615/9mzk-sp93

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0DataRank · unranked

0 citations

Stefano Costanzi, Andrei A. Ivanov, Ingrid Fricks, Serge Van Calenbergh, Kenneth A. Jacobson +5 more

Phospholipase C isozymes as effectors of Ras superfamily GTPases

UNC Libraries(2020)10.17615/9yv7-e338

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0DataRank · unranked

0 citations

T. Kendall Harden, Stephanie N. Hicks, John Sondek

Agonist Versus Antagonist Action of ATP at the P2Y 4 Receptor Is Determined by the Second Extracellular Loop

UNC Libraries(2020)10.17615/3a4v-zn14

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0 citations

Ai Dong Qi, Robert A. Nicholas, Christopher L. Herold, T. Kendall Harden

Potent and Selective Peptide-based Inhibition of the G Protein Gαq

UNC Libraries(2020)10.17615/yq12-cq22

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0DataRank · unranked

0 citations

Brian D. Strahl, Krzysztof Krajewski, Gary L. Waldo, Thomas H. Charpentier, T. Kendall Harden +3 more

Molecular dynamics simulation of the P2Y14 receptor. Ligand docking and identification of a putative binding site of the distal hexose moiety

UNC Libraries(2020)10.17615/m7gg-5z22

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Andrei A. Ivanov, Kenneth A. Jacobson, T. Kendall Harden, Ingrid Fricks

Polyamidoamine (PAMAM) Dendrimer Conjugates of “Clickable” Agonists of the A 3 Adenosine Receptor and Coactivation of the P2Y 14 Receptor by a Tethered Nucleotide

UNC Libraries(2020)10.17615/wk9d-zk24

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0 citations

Zhan Gao, Matthew O. Barrett, Kenneth A. Jacobson, T. Kendall Harden, Ingrid Fricks +5 more

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5′-triphosphate analogues at the human P2Y2 and P2Y4 receptors

UNC Libraries(2020)10.17615/2w5x-0707

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0 citations

Zhan‐Guo Gao, T. Kendall Harden, Andrei A. Ivanov, Stefano Costanzi, Kenneth A. Jacobson +3 more

Constitutive Release of ATP and Evidence for Major Contribution of Ecto-nucleotide Pyrophosphatase and Nucleoside Diphosphokinase to Extracellular Nucleotide Concentrations

UNC Libraries(2021)10.17615/dddg-bj46

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4 citations

T. Kendall Harden, Eduardo R. Lazarowski, Richard C. Boucher

Human P2Y 14 Receptor Agonists: Truncation of the Hexose Moiety of Uridine-5′-Diphosphoglucose and Its Replacement with Alkyl and Aryl Groups

Figshare(2021)10.17615/gnkz-fx16

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1 citations

Lauren E. Burianek, Kenneth A. Jacobson, T. Kendall Harden, M. Barrett, Hyojin Ko +1 more

Dominant-negative Inhibition of Pheromone Receptor Signaling by a Single Point Mutation in the G Protein α Subunit

UNC Libraries(2021)10.17615/ne7k-s595

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0 citations

Yuh-Lin Wu, Henrik Dohlman, T. Kendall Harden, Shelley B. Hooks

RhoA Activates Purified Phospholipase C-ϵ by a Guanine Nucleotide-dependent Mechanism

UNC Libraries(2021)10.17615/91b8-gp61

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0 citations

Svetlana Gershburg, Michele R. Wing, Jason P. Seifert, Jason T. Snyder, T. Kendall Harden +1 more

Role of Isoprenoid Lipids on the Heterotrimeric G Protein γ Subunit in Determining Effector Activation

UNC Libraries(2021)10.17615/zedg-9576

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0 citations

Wendy W. Liu, T. Kendall Harden, James C. Garrison, Hiroshi Yasuda, Chang Seon Myung

Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ 13

UNC Libraries(2021)10.17615/vjg3-b325

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0 citations

Douglas A. Bayliss, Qiubo Lei, Rebecca A. Morris, Jennie R. Hillmann, Richard J. Miller +6 more

Charged residues in the C-terminus of the P2Y1 receptor constitute a basolateral-sorting signal

UNC Libraries(2021)10.17615/bx3a-7034

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0 citations

Robert A. Nicholas, Ai Dong Qi, T. Kendall Harden, Samuel C. Wolff

Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.03.013

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0DataRank · unranked

9 citations

Tasha N. Blatt, Tomohiro Kawano, Emily G. Clark, Nigel Mackman, Sebastian Murcia +6 more

Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro

UNC Libraries(2025)10.17615/g5hd-0m20

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0 citations

Sebastian Murcia, Tomohiro Kawano, David S. Paul, Wolfgang Bergmeier, Nigel Mackman +7 more