🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Fostering Data Sharing

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Chris J. Frangieh

Chris J. Frangieh

Massachusetts Institute of Technology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.3Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A molecular single-cell lung atlas of lethal COVID-19

Nature(2021)10.1038/s41586-021-03569-1

Top 4%

5.3DataRank

Top 4%737 citations

Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore +39 more

Papers

Driven by 13 papers — median percentile 96. Top paper: “A molecular single-cell lung atlas of lethal COVID-19”.

A molecular single-cell lung atlas of lethal COVID-19

Nature(2021)10.1038/s41586-021-03569-1

Top 4%

5.3DataRank

Top 4%737 citations

Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore +39 more

Scalable genetic screening for regulatory circuits using compressed Perturb-seq

Nature Biotechnology(2023)10.1038/s41587-023-01964-9

N/A

2.2DataRank · unranked

96 citations

Loic Binan, Jon Bezney, Brooke Simonton, Jahanara Freedman, Chris J. Frangieh +8 more

Compressed Perturb-seq: highly efficient screens for regulatory circuits using random composite perturbations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.525200

N/A

0.505DataRank · unranked

9 citations

Loic Binan, Jon Bezney, Brooke Simonton, Jahanara Freedman, Chris J. Frangieh +8 more

Single cell RNA-seq by mostly-natural sequencing by synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.29.493705

N/A

0.399DataRank · unranked

1 citations

Gila Lithwick-Yanai, Xian Adiconis, Florian Oberstrass, Nika Iremadze, Kathryn Geiger-Schuller +11 more

Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing

Nature Biotechnology(2022)10.1038/s41587-022-01452-6

N/A

0DataRank · unranked

53 citations

Gila Lithwick‐Yanai, Xian Adiconis, Florian C. Oberstrass, Nika Iremadze, Kathryn Geiger-Schuller +9 more

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.21.485049

N/A

0DataRank · unranked

10 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Shivem B. Shah, Zachary Walsh +21 more

The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Cancer Cell(2023)10.1016/j.ccell.2023.05.014

N/A

0DataRank · unranked

96 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah +28 more

Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription

Science(2023)10.1126/science.adg7883

N/A

0DataRank · unranked

74 citations

Chris J. Frangieh, Rhiannon K. Macrae, Feng Zhang, Max E. Wilkinson

Scalable generation and functional classification of genetic variants in inborn errors of immunity to accelerate clinical diagnosis and treatment

Cell(2025)10.1016/j.cell.2025.05.037

N/A

0DataRank · unranked

12 citations

Chris J. Frangieh, Neeharika Kothapalli, Jay A. Levy, Clarissa Heck, Johannes C. Melms +11 more

Massively scalable generation, discovery, and clinical (re-)classification of inborn errors of immunity using cutting-edge genome engineering 4011

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1746

N/A

0DataRank · unranked

0 citations

Chris J. Frangieh, Clarissa Heck, Sarah Grauman, Jared Pollard, Lei Huang +5 more

A portable single-sided magnetic-resonance sensor for the grading of liver steatosis and fibrosis

Nature Biomedical Engineering(2020)10.1038/s41551-020-00638-0

N/A

0DataRank · unranked

29 citations

Chris J. Frangieh, Siavash Raigani, Jeremy Sogo, Roderick T. Bronson, Korkut Uygun +4 more

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.267211

N/A

0DataRank · unranked

5 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn R. Geiger-Schuller, Patricia Ho, Adrienne Luoma +15 more

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Nature Genetics(2021)10.1038/s41588-021-00779-1

N/A

0DataRank · unranked

271 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Patricia Ho, Adrienne Luoma +17 more