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Mitochondrial Transplantation Promotes Protective Effector and Memory CD4 + T Cell Response During Mycobacterium Tuberculosis Infection and Diminishes Exhaustion and Senescence in Elderly CD4 + T cells

Advanced Science(2024)10.1002/advs.202401077Source: DataRank Database

Mitochondrial Transplantation Promotes Protective Effector and Memory CD4 + T Cell Response During Mycobacterium Tuberculosis Infection and Diminishes Exhaustion and Senescence in Elderly CD4 + T cells is a research paper published in Advanced Science (2024). On theSindex it has a DataRank of 0. It has been cited 14 times.

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Open Access14 citations

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Enrichment:Funding (18 grants)OA: goldTopics (41)IDs (PubMed)SDGs (1)

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Authors (10)

Shalini Gautam ORCID,Angélica M. Olmo-Fontánez ORCID,Andreu Garcia‐Vilanova ORCID,Varun Dwivedi ORCID,Alyssa Schami ORCID

Live enrichment

PubMed:39039808

National Heart, Lung, and Blood Institute

Grant: 1T32HL098049

National Institutes of Health

Grant: 1P30AI168439-01

Interdisciplinary NexGen TB research Advancement Center (IN-TRAC)

National Institutes of Health

Grant: 1F99AG079802-01

Elucidate the adverse impact of mitochondria-induced oxidative stress in molecular and cellular determinants in the aging lung, driving susceptibility to Mycobacterium tuberculosis infection

National Institutes of Health

Grant: 1S10OD028653-01

BD FACSymphony

National Institutes of Health

Grant: 1T32HL098049-01A1

Mechanisms in Innovation in Vascular Disease

National Institutes of Health

Grant: 3P01AG051428-05S1

Downstream sample analyses from 3 NHP species infected with SARS-CoV-2.

The Burroughs Wellcome Fund Postdoctoral Diversity Enrichment Program

Grant: 1069497

Texas Biomedical Research Institute Interdisciplinary NexGen TB Research Advancement Center (IN-TRAC), an NIH-funded program

Grant: P30-AI168439

NIH HHS

Grant: S10 OD028653

NIA NIH HHS

Grant: F99 AG079802

National Institute on Aging of the National Institutes of Health

Grant: P01AG051428

NIAID NIH HHS

Grant: P30 AI168439

NHLBI NIH HHS

Grant: T32 HL098049

NIH HHS

Grant: P51 OD011133

Douglass Foundation Graduate Student Fellowship

Stanford University Propel Post-Doctoral Fellowship

The Texas Biomed Research Institute Post-Doctoral Forum Grant

Wellcome Trust

goldLicense: cc-by

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/advs.202401077

publisherhttps://advanced.onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202401077

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11423092/pdf/ADVS-11-2401077.pdf

https://doi.org/10.1002/advs.202401077

Fields of Study

03 medical and health sciences0302 clinical medicineCD4-Positive T-LymphocytesHumansMiceAnimalsMitochondriaMycobacterium tuberculosisTuberculosisDisease Models, AnimalAgedCellular SenescenceMaleFemaleMice, Inbred C57BLAging

MeSH Terms

CD4-Positive T-LymphocytesHumansMiceAnimalsMitochondriaMycobacterium tuberculosisTuberculosisDisease Models, AnimalAgedCellular SenescenceMaleFemaleMice, Inbred C57BLAging

Keywords

CD4+ T CellsT cell exhaustionT cell senescencecellular reprogrammingimmune agingimmunometabolismmitochondrial dysfunctionmitochondrial reprogrammingmitochondrial transplantationoxidative stresstuberculosis

Sustainable Development Goals

SDG 3: 3. Good health