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Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential

Advanced Science(2025)10.1002/advs.202404260Source: DataRank Database

Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential is a research paper published in Advanced Science (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)Impact (FWCI 0.42)OA: goldTopics (59)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (23)

Marie Arlotto ORCID,Justin M. Overhulse ORCID,Tuan‐Anh Dinh,Yingsheng Zhou,Nathan J. Dupper

Live enrichment

PubMed:39821709 PMC:PMC11904993 OpenAlex:https://openalex.org/W4406485143

National Institutes of Health

Grant: GM147537

Agence Nationale de la Recherche

Grant: ANR‐14‐CE16‐0027

Agence Nationale de la Recherche

Grant: ANR‐18‐CE18‐0007

Agence Nationale de la Recherche

Grant: ANR‐21‐CE18‐0041

NIGMS NIH HHS

Grant: T32 GM118289

Agence Nationale de la Recherche

Grant: ANR-21-CE18-0041

Developing fungal bromodomain inhibitors as a potential new class of antifungal drugs

Agence Nationale de la Recherche

Grant: ANR-18-CE18-0007

Developing BET proteins inhibitors as a novel class of antifungal drugs

Agence Nationale de la Recherche

Grant: ANR-14-CE16-0027

Investigating a potential new anti-fungal drug target: Structure, function and inhibition of fungal BET bromodomains

NIGMS NIH HHS

Grant: R01 GM147537

French National Research Agency (ANR)

Grant: ANR-17-EURE-0003

National Institutes of Health

Grant: 5R01GM147537-03

Efficient synthon-based modular screening of Giga-to-Terra-scale virtual libraries

French National Research Agency (ANR)

Grant: ANR-10-INBS-0005

National Institutes of Health

Grant: 5T32GM118289-05

CBI: Chemistry Biology Interface

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

LABoratoires d'EXcellence GRAL

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Fondation Innovations en Infectiologie

Fondation Innovations en Infectiologie (FINOVI)

Université Grenoble Alpes

LABoratoires d'EXcellence GRAL

Fondation Innovations en Infectiologie

Université Grenoble Alpes

Fondation Innovations en Infectiologie (FINOVI)

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

FWCI

0.42

Citation Percentile

0.5%

Citation Trend

2025

goldLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/advs.202404260

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/advs.202404260

publisherhttps://advanced.onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202404260

journalhttps://doi.org/10.1002/advs.202404260

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39821709

Fields of Study

Protein Degradation and InhibitorsPeptidase Inhibition and AnalysisPlant Virus Research Studies0301 basic medicine03 medical and health sciencesAntifungal AgentsHumansCandidaTranscription FactorsFungal ProteinsCandida glabrataDrug DiscoveryAnimals

MeSH Terms

AnimalsAntifungal AgentsCandidaFungal ProteinsHumansMicrobial Sensitivity TestsTranscription FactorsCandida glabrataDrug Discovery

Keywords

BromodomainAntifungalBRD4Candida glabrataComputational biologyBiologyYeastChemistryMicrobiologyGeneticsGeneEpigeneticsCandidaBet InhibitionBdf1Antifungal Agents[SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM][CHIM.THER] Chemical Sciences/Medicinal ChemistryScienceMolecular Biology/Biochemistry [q-bio.BM]610[SDV.BBM.BS]Life Sciences [q-bio]/BiochemistryFungal Proteins[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesDrug DiscoveryHumansAnimals[SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM][SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/MycologyMolecular Biology/Structural Biology [q-bio.BM]Q[SDV.MP.MYC] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology620[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesResearch ArticleTranscription Factors

Sustainable Development Goals

SDG 0: Life in Land