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Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease

Alzheimer s & Dementia(2022)10.1002/alz.12813Source: DataRank Database

Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease is a research paper published in Alzheimer s & Dementia (2022). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (21 grants)Impact (FWCI 0.61)OA: hybridTopics (64)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (26)

Yihan Li ORCID,Christopher Fowler ORCID,James D. Doecke ORCID,Yen Ying Lim ORCID,Candace Drysdale

Live enrichment

PubMed:36349985 PMC:PMC10166765 OpenAlex:https://openalex.org/W4308607521

National Health and Medical Research Council

Grant: 1048082

P2X7 mediated phagocytosis of apoptotic cells: a common mechanism underlies neurological and eye disorders

National Health and Medical Research Council

Grant: 1061419

The role of purines in Age Related Macular Degeneration

National Health and Medical Research Council

Grant: 1120095

The role of reduced phagocytosis in the pathogenesis of Age-related Macular Degeneration

National Health and Medical Research Council

Grant: 110178

Bethlehem Griffiths Research Foundation

Grant: BGRF1901

National Institutes of Health

Grant: AG058252

National Institutes of Health

Grant: AG073979

National Institutes of Health

Grant: AG051848

NIA NIH HHS

Grant: P30 AG066530

NIA NIH HHS

Grant: U24 AG057437

NIA NIH HHS

Grant: R01 AG051848

NIA NIH HHS

Grant: RF1 AG073979

NIA NIH HHS

Grant: P30 AG062429

NIA NIH HHS

Grant: R01 AG058252

NIA NIH HHS

Grant: U01 AG010483

NIA NIH HHS

Grant: R01 AG073979

National Institutes of Health

Grant: 1R01AG058252-01

A Blood Test for Screening Into Alzheimer's Prevention Trials

National Institutes of Health

Grant: 5R01AG051848-02

A Proinflammatory Endophenotype to Predict NSAID Treatment Response Alzheimer's Disease Clinical Trials

Australian Research Council (ARC)

Grant: FT120100581

The role of P2X7 and P2X4 receptor mediated innate phagocytosis in pathogenesis and treatment of neurodegenerative diseases

National Institutes of Health

Grant: 1R01AG073979-01

Precision Medicine for Inflammatory Treatment for Alzheimer's Disease in Down Syndrome

National Institute on Aging

FWCI

0.61

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

hybridLicense: cc-by-nc-nd

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12813

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12813

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12813

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/alz.12813

publisherhttps://alz-journals.onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12813

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsImmune responses and vaccinations

MeSH Terms

Alzheimer DiseaseHumansImmunity, InnateLeukocytesBiomarkersAmyloid beta-Peptides

Keywords

ImmunologyDiseaseInnate immune systemDownregulation and upregulationMedicineAntigenCD163ImmunophenotypingImmunityBiologyImmune systemPathologyPhenotypeGeneAlzheimer's diseaseComplement systemCD59CD91ROC curveReceptor For Advanced Glycation End Products (Rage)Cd11cPeripheral Immune ResponseLeukocyte BiomarkerInnate PhagocytosisAgingBiological PsychologyClinical Sciences610NeurodegenerativeAlternate Format Research ArticlesAlzheimer DiseaseDiagnosisMedicine and Health SciencesAcquired Cognitive ImpairmentLeukocytesPsychology2.1 Biological and endogenous factorsInnateHumansDiagnostic and Therapeutic Techniques and EquipmentAmyloid beta-PeptidesBiomedical and Clinical SciencesPreventionNeurosciencesAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)600Analyticalreceptor for advanced glycation end productsImmunity, InnateBrain Disorders4.1 Discovery and preclinical testing of markers and technologiesGeriatricsNeurologicalDementiaBiomarkers

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being