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TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics

Angewandte Chemie International Edition(2020)10.1002/anie.202006280Source: DataRank Database

TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics is a research paper published in Angewandte Chemie International Edition (2020). On theSindex it has a DataRank of 0. It has been cited 73 times.

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Open Access73 citations

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Enrichment:Funding (7 grants)OA: hybridTopics (31)IDs (PubMed, PMC)Annotations (1)

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Authors (21)

Marco Potowski,Mohammad Akbarzadeh,Mateja Klika Škopić,Denise dos Santos Smith,Lukas Arendt

Live enrichment

PubMed:32537835 PMC:PMC7689693

Deutsche Forschungsgemeinschaft

Grant: BR 5049/3-1

European Commission

Grant: H2020-MSCA-ITN-2015

National Institutes of Health

Grant: 2R01GM097082-05

Real-time discovery of inhibitors among billion compounds for preview and download

Hartstichting

Grant: ESCAPE-HF, 2018B012

NIGMS NIH HHS

Grant: R01 GM097082

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

European Commission

Grant: 675179

Targeted small-molecule Stabilisation of Protein-Protein Interactions

hybridLicense: CC BY

publisherhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.202006280

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202006280

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/anie.202006280

Europe_PMChttps://europepmc.org/articles/PMC7689693

Europe_PMChttps://europepmc.org/articles/PMC7689693?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansIndolesTranscription FactorsDNAProtein BindingProto-Oncogene Proteins c-mdm2Peptidomimetics

Keywords

combinatorial chemistryPeptidomimeticsUgi ReactionProtein-protein Interaction InhibitionDna-encoded Library570Indolesinfo:eu-repo/classification/ddc/540protein–protein interaction inhibitionDESIGNHumansinfo:eu-repo/classification/ddc/570HIPPO PATHWAYProto-Oncogene Proteins c-mdm2DNA540CommunicationsPROTEIN-PROTEIN INTERACTIONDISCOVERYProtein BindingTranscription Factors