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Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

Angewandte Chemie International Edition(2025)10.1002/anie.202524718Source: DataRank Database

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines is a research paper published in Angewandte Chemie International Edition (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Enrichment:Funding (11 grants)OA: hybridTopics (11)IDs (PubMed, PMC)Annotations (3)

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Authors (8)

L. Zhao ORCID,Shengchun Wang ORCID,Huichong Liu,Yu Zhang ORCID,Binh Khanh Mai

Live enrichment

PubMed:41451513 PMC:PMC12834331

National Institutes of Health

Grant: R35GM147387

National Science Foundation

Grant: CHE‐2400087

National Science Foundation

Grant: OAC‐2117681

National Science Foundation

Grant: OAC‐2138259

National Science Foundation

Grant: OAC-2138259

National Science Foundation

Grant: CHE-2400087

Alfred P. Sloan Research Fellow

Grant: FG-2024-22244

National Science Foundation

Grant: OAC-2117681

Camille Dreyfus Teacher-Scholar

Grant: TC-25-084

David & Lucile Packard Fellow

Grant: 2023-76169

Howard Hughes Medical Institute

hybridLicense: cc-by-nc-nd

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.202524718

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202524718

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/anie.202524718

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12834331/

Europe_PMChttps://europepmc.org/articles/PMC12834331

MeSH Terms

Aspergillus nidulansNitrogenOxidoreductasesNonheme Iron ProteinsDirected Molecular EvolutionStereoisomerismBiocatalysis

Keywords

Amino acidsAsymmetric synthesisBiocatalysisNonheme Fe Enzyme

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

FAIR Checklist

Authors (8)

Funding (11 grants)

Open Access

Topics

Annotations (Europe PMC)