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Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization

Arthritis & Rheumatology(2023)10.1002/art.42538Source: DataRank Database

Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization is a research paper published in Arthritis & Rheumatology (2023). On theSindex it has a DataRank of 0. It has been cited 40 times.

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Enrichment:Funding (61 grants)Impact (FWCI 8.59)OA: hybridTopics (34)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Authors (37)

Eleanor Wheeler ORCID,Maik Pietzner ORCID,Till F. M. Andlauer ORCID,Michelle S. Yau ORCID,April Hartley ORCID

Live enrichment

PubMed:37096546 PMC:PMC10586470 OpenAlex:https://openalex.org/W4366990889

European Research Area Network on Cardiovascular Diseases

Grant: 01KL1802

National Heart, Lung, and Blood Institute

Grant: R01‐HL‐105756

National Heart, Lung, and Blood Institute

Grant: R01‐HL‐146860

National Heart, Lung, and Blood Institute

Grant: R01‐HL‐142809

National Heart, Lung, and Blood Institute

Grant: R01‐HL‐159514

National Key Research and Development Program of China

Grant: 2022YFC2505203

Wellcome Trust

Grant: WT092830M

Wellcome Trust

Grant: WT088806

Wellcome Trust

Grant: WT102215/2/13/2

Wellcome Trust

Grant: 20378/Z/16/Z

UK Medical Research Council

Grant: G1001357

The menopausal transition and healthy ageing and wellbeing

NIH

Grant: N01‐AR‐2‐2258

NIH

Grant: N01‐AR‐2‐2259

NIH

Grant: N01‐AR‐2‐2260

NIH

Grant: N01‐AR‐2‐2261

NIH

Grant: N01‐AR‐2‐2262

NIH

Grant: R01‐AR‐075356

NIH

Grant: P30‐DK‐072488

National Health and Medical Research Council

Grant: GNT1177938

Horizon 2020

Grant: grant agreement ID 848146

American Heart Association

Grant: 18TPA34230025

Medical Research Council

Grant: G9815508

NIAMS NIH HHS

Grant: P30 AR072571

NHLBI NIH HHS

Grant: R01 HL105756

Medical Research Council

Grant: MC_PC_19009

NHLBI NIH HHS

Grant: R01 HL142809

Medical Research Council

Grant: MC_UU_00006/1

Novo Nordisk Fonden

Grant: NNF14OC0010513

Novo Nordisk Fonden

Grant: NNF19OC0055250

NIAMS NIH HHS

Grant: R01 AR075356

Medical Research Council

Grant: MC_PC_15018

NIH HHS

Grant: N01-AR-2-2260

NIH HHS

Grant: N01-AR-2-2262

Novo Nordisk Fonden

Grant: NNF13OC0005785

NIDDK NIH HHS

Grant: P30 DK072488

NHLBI NIH HHS

Grant: R01 HL146860

NHLBI NIH HHS

Grant: R01 HL159514

Medical Research Council

Grant: MC_UU_00032/1

NIH HHS

Grant: N01-AR-2-2261

Novo Nordisk Fonden

Grant: NNF18OC0033898

Novo Nordisk Fonden

Grant: NNF22OC0078421

NHLBI NIH HHS

Grant: R01 HL148239

Wellcome Trust

Grant: 102215

The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019.

NIH HHS

Grant: N01-AR-2-2259

Wellcome Trust

Grant: WT102215

Wellcome Trust

Grant: 217065/Z/19/Z

Medical Research Council

Grant: MC_UU_00011/1

Mendelian randomization to hypothesis-free causal inference

NIH HHS

Grant: N01-AR-2-2258

NHLBI NIH HHS

Grant: R01 HL162928

European Commission

Grant: 848146

A high-dimensional approach for unwinding immune-metabolic causes of cardiovascular disease-depression multimorbidities

National Institutes of Health

Grant: 5R01HL146860-02

Whole-genome sequencing analysis of coronary atherosclerosis and related traits

Wellcome Trust

Grant: 088806

Genome-wide association study of maternal pregnancy phenotypes and later-life maternal and offspring vascular and metabolic phenotypes.

Wellcome Trust

Grant: 092830

The relationship of the menopausal transition to healthy aging and chronic disease risk.

National Institutes of Health

Grant: 5P30DK072488-02

CORE--ADIPOSE TISSUE BIOLOGY AND BASIC MECHANISMS

National Institutes of Health

Grant: 5R01HL159514-03

Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction

National Institutes of Health

Grant: 2R01HL105756-07

CHARGE consortium: gene discovery for CVD and aging phenotypes

National Institutes of Health

Grant: 3R01HL142809-03S1

The Role of Histone Deacetylase 9 in Vascular Calcification

National Institutes of Health

Grant: 5R01AR075356-03

Systemic contribution of age-associated epigenetic mechanisms to osteoarthritis

University of Bristol

Wellcome Trust

FWCI

8.59

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42538

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42538

publisherhttps://acrjournals.onlinelibrary.wiley.com/doi/pdf/10.1002/art.42538

journalhttps://doi.org/10.1002/art.42538

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37096546

Fields of Study

Bone health and osteoporosis researchGenetic Associations and EpidemiologyParathyroid Disorders and Treatments03 medical and health sciences0302 clinical medicineHumansGenome-Wide Association StudyDiabetes Mellitus, Type 2Mendelian Randomization AnalysisAtherosclerosisMyocardial InfarctionRisk FactorsHypertensionPolymorphism, Single Nucleotide

MeSH Terms

Diabetes Mellitus, Type 2HumansHypertensionMyocardial InfarctionRisk FactorsPolymorphism, Single NucleotideAtherosclerosisGenome-Wide Association StudyMendelian Randomization Analysis

Keywords

Mendelian randomizationSclerostinMedicineInternal medicineBioinformaticsGeneticsBiologyGeneGenetic variantsWnt signaling pathwayGenotype

Sustainable Development Goals

SDG 0: Good health and well-being