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Small‐Molecule Sarco/Endoplasmic Reticulum Ca 2+ ‐ATPase Activators Reverse Methylglyoxal‐Induced Inhibition through Nonantioxidant Mechanisms

ChemMedChem(2025)10.1002/cmdc.202500968Source: DataRank Database

Small‐Molecule Sarco/Endoplasmic Reticulum Ca 2+ ‐ATPase Activators Reverse Methylglyoxal‐Induced Inhibition through Nonantioxidant Mechanisms is a research paper published in ChemMedChem (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (6 grants)OA: hybridTopics (21)IDs (PubMed, PMC)

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Authors (5)

Silvia Micháliková ORCID,Petronela Rezbáriková ORCID,L. Michel Espinoza‐Fonseca ORCID,Jana Viskupičová ORCID,Carlos Cruz‐Cortés ORCID

Live enrichment

PubMed:41319342 PMC:PMC12716067

Open Mobility Program grant

Grant: Open-Mob-2024-11

NHLBI NIH HHS

Grant: R01 HL176212

NIH grants

Grant: R01HL148068

Slovak Grants

Grant: VEGA 2/0063/22

Slovak Grants

Grant: APVV-24-0186

Slovak Grants

Grant: VEGA 2/0127/25

hybridLicense: cc-by

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cmdc.202500968

publisherhttps://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202500968

publisherhttps://chemistry-europe.onlinelibrary.wiley.com/doi/full-xml/10.1002/cmdc.202500968

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12716067/

Europe_PMChttps://europepmc.org/articles/PMC12716067

MeSH Terms

AnimalsHumansCalciumPyruvaldehydeEnzyme ActivatorsEnzyme InhibitorsAntioxidantsMolecular StructureStructure-Activity RelationshipDose-Response Relationship, DrugSarcoplasmic Reticulum Calcium-Transporting ATPasesSmall Molecule Libraries

Keywords

CalciumEndoplasmic reticulumLipid PeroxidationDPPHDiabetesactivatorsMethylglyoxalAbtsSarco/endoplasmic Reticulum Ca2+‐atpase