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Synergistic Effects of Riluzole and Sodium Butyrate on Barrier Function and Disease Progression of Amyotrophic Lateral Sclerosis Through the Gut‐Neuron Axis

Comprehensive physiology(2025)10.1002/cph4.70009Source: DataRank Database

Synergistic Effects of Riluzole and Sodium Butyrate on Barrier Function and Disease Progression of Amyotrophic Lateral Sclerosis Through the Gut‐Neuron Axis is a research paper published in Comprehensive physiology (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 6.00)OA: hybridTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

KaReisha Robinson,Yinglin Xia ORCID,Jun Sun ORCID,Yongguo Zhang ORCID

Live enrichment

PubMed:40176466 PMC:PMC11966087 OpenAlex:https://openalex.org/W4409148466

National Institutes of Health

Grant: R01DK114126

National Institutes of Health

Grant: R01DK105118

National Institutes of Health

Grant: R01DK134343

U.S. Department of Veterans Affairs

Grant: I01BX004824‐06

BLRD VA

Grant: I01 BX004824

U.S. Department of Veterans Affairs

Grant: I01BX004824-06

National Institutes of Health

Grant: 5R01DK114126-04

How Vitamin D Receptor Influences Intestinal Barrier Functions

National Institutes of Health

Grant: 5R01DK105118-05

Vitamin D Receptor Regulation of Microbiota in Intestinal Epithelia

National Institutes of Health

Grant: 5I01BX004824-04

Microbiome and intestinal barrier in ALS therapy

National Institutes of Health

Grant: 5R01DK134343-03

Vitamin D Receptor Regulation of Microbiota in Intestinal Epithelia

FWCI

6.00

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cph4.70009

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cph4.70009

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/cph4.70009

journalhttps://doi.org/10.1002/cph4.70009

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40176466

Fields of Study

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration MechanismsNeurological diseases and metabolism03 medical and health sciences0302 clinical medicine

MeSH Terms

Superoxide Dismutase-1Amyotrophic Lateral SclerosisAnimalsDisease Models, AnimalDrug SynergismMaleMice, TransgenicNeuronsDisease ProgressionNeuroprotective AgentsRiluzoleButyric AcidMice

Keywords

RiluzoleSodium butyrateAmyotrophic lateral sclerosisPharmacologyChemistryButyrateMedicineInternal medicineBiochemistryDiseaseNeuronInflammationBBBTight junctionsBarrier FunctionZo‐1Gut‐brain AxisClaudin‐5MaleNeuronsMice, TransgenicDrug SynergismMiceDisease Models, AnimalNeuroprotective AgentsSuperoxide Dismutase-1Disease ProgressionAnimalsButyric AcidResearch Article

Sustainable Development Goals

SDG 0: Clean water and sanitation